A new drug delivery system has been developed using nanoparticles embedded in liposomes that can be triggered by non-invasive electromagnetic fields. The system can control the rate and extent of drug release, with a quick release in just 30-40 minutes.
A new study by Stanford University climate scientists predicts that exceptionally long heat waves and hot events will be frequent in the US by 2039, posing risks to agriculture and human health. The researchers used climate models to project a 1.8-degree Fahrenheit increase in global temperature, leading to more intense heat extremes.
The Fogarty International Center of the NIH has awarded a five-year, $3.6 million grant to an international AIDS training and research program to continue training foreign researchers in developing countries. The program supports established research training programs in India, Cambodia, the Philippines, and Kenya, and will also focus ...
Researchers found teenage mothers more likely to have premature babies due to biological immaturity and social factors. The study highlights the importance of antenatal care and post-natal contraception for pregnant teenagers.
McMaster University researchers have made a breakthrough in understanding the molecular mechanisms of hereditary colorectal cancers. They discovered how a specific protein, MutL, works within cells to repair DNA errors, paving the way for alternative cancer treatments and assessment tools.
A new dinosaur species with a heart-shaped frill has been discovered in Canada's Alberta and Saskatchewan provinces, named Mojoceratops perifania. The species is related to Triceratops but appeared 10 million years earlier, survived for only one million years.
Researchers discovered a chemical that promotes brain cell growth, potentially leading to new treatments for Alzheimer's and neurodegenerative diseases. The substance protects newborn neurons from dying off, giving them better odds of becoming functional cells.
A study found that perfusion CT can detect hemodynamic changes in liver tissue, indicating drug-induced hepatic damage. The research team correlated perfusion CT parameters with ALT levels and treatment cycles, revealing increased HPI and MTT in patients undergoing chemotherapy.
A study found that corporate press releases are not associated with positive or negative company performance, as companies with negative results also use these releases to improve their image. The researchers suggest cultural and financial factors contribute to this phenomenon.
Researchers discovered a specific microRNA sequence, microRNA-212, that protects rats from cocaine addiction by regulating CREB signaling. This finding suggests microRNAs may play a crucial role in vulnerability to addiction, offering new promise for anti-addiction medications.
The new standards provide information on organizational policies, staffing ratios, intake screening, and suicide prevention. They are designed to help correctional professionals develop effective rehabilitation programs for mentally ill individuals.
The foundation named 18 new Damon Runyon Fellows for their innovative cancer research, including studies on gene regulation, immune response, and tumor development. The recipients will receive $156,000 each to pursue novel ideas.
Radha Charan Gupta will be the first Indian to receive the prize for his contributions to the history of mathematics, specifically work on trigonometry in India.
JILA team finds similar behavior in ultracold atomic gases and high-temperature superconductors, supporting the idea that studying superfluidity in atomic gases can help understand complicated superconductors. The discovery lends support to the concept of a 'pseudo-gap region' where atom pairing occurs above critical temperature.
A new study published in Applied Research in Quality of Life found that positive emotions and life satisfaction are strong predictors of physical health in teenagers. Researchers analyzed data from 401 students aged 12-14 and found that subjective well-being was a significant unique predictor of physical health outcomes.
Researchers use mesoporous silica nanoparticles to store and deliver chemotherapeutic drugs, effectively suppressing tumors in mice. The treatment led to significant tumor regression and minimal toxicity.
Geologists found a lower density fault zone in the 2004 Sumatra earthquake, allowing it to slip over a longer segment and reach closer to the seafloor, generating larger tsunami waves. The study's findings could help improve hazard assessment and mitigation for this region.
The National Institute of Allergy and Infectious Diseases has funded 10 international centers for excellence in malaria research, with a focus on cutting-edge research in endemic areas. The program aims to generate critical knowledge, tools, and evidence-based strategies to support intervention and control programs in regions most affe...
A University of Oklahoma researcher is developing a novel therapy for Alzheimer's disease by targeting the toxic plaque in the brain. The therapy uses biopharmaceutical proteases that can degrade thousands of plaque molecules, potentially delivering a catalytic benefit even if only small amounts pass through the cell barrier.
The University of California, San Diego will lead a seven-year, $9.2 million NIH grant-funded effort to study and understand the complete disease cycle of malaria in the Amazon basin. The goal is to comprehensively address the ongoing public health problem of malaria, which affects over 3 billion people worldwide.
A MSU-led research team will use the grant to create new prevention and control strategies for malaria in Malawi, focusing on identifying factors contributing to the disease's incidence and prevalence. The team aims to tailor strategies to specific seasons and locations.
Researchers have discovered a monoclonal antibody that is effective against multiple strains of influenza, including Avian H5N1, seasonal H1N1, and the 2009 Swine H1N1 influenza. The antibody targets a conserved region of the viral coat protein, providing broad-spectrum protection against various flu strains.
Physicists at NIST have demonstrated an ion trap with a built-in optical fiber, enabling the measurement of quantum information stored in ions. The device simplifies quantum computer design and paves the way for swapping information between matter and light in future quantum networks.
Experts warn that failure to meet universal access pledge and budget cuts to prevention and treatment programs will deliver a major setback. Many African countries face depleting stocks of antiretroviral medications and reduced treatment coverage goals, increasing the risk of HIV drug resistance.
Patients with stage IV flat foot deformity experience improved alignment, reduced arthritis, and enhanced mobility after a new surgery developed at Hospital for Special Surgery. The study shows promising results, including the maintenance of correction nine years post-surgery.
Researchers are developing an EHR system to improve nursing care coordination and advance technology use in long-term care. The goal is to integrate clinical information systems with passive monitoring data to enhance clinical decision-making and patient outcomes.
Poor problem-solving skills are a significant predictor of both bullying and being a victim, according to new research. The study found that boys bully more than girls, and individuals with academic troubles are more likely to become bullies.
A Tel Aviv University biologist challenges the idea that islands have unique evolutionary patterns, citing research that shows no extraordinary effects of isolation. He found that evolutionary processes on islands are not different from those on mainland ecosystems, contradicting popular myths about island-bred creatures.
Researchers identified Musashi 2 as a predictive marker for prognosis in AML and CML patients. High levels of Musashi 2 associated with increased cell proliferation, decreased maturation, and aggressive cancer behavior.
Researchers have discovered that vitamin B3 can inhibit the growth of Candida albicans and Aspergillus fumigatus, two major human pathogens. The study found that nicotinamide, a form of vitamin B3, can reduce virulence in both normal and drug-resistant strains of C. albicans.
A simple diagnostic tool predicts type 2 diabetes in Vietnamese individuals based on high systolic blood pressure and waist-to-hip ratio. The prevalence of undiagnosed diabetes is estimated to be around 11% for men and 12% for women, with approximately 350,000 people affected in Ho Chi Minh City.
A new study finds that endoscopic ultrasound (EUS) is associated with improved outcomes in patients with localized pancreatic cancer. EUS evaluation was found to improve overall survival, possibly due to earlier cancer detection and more selective surgery. The study analyzed a large population-based cancer registry and demonstrated the...
Research suggests that SE5-OH containing Natural S-equol can help alleviate hot flushes and other menopausal symptoms. Additionally, studies have found that soy-based diets may help prevent bone loss in postmenopausal women.
A study found individuals with high resting heart rates and low beat-to-beat heart rate variability have a higher risk of developing kidney disease. The autonomic nervous system's behavior may be a sentinel marker for late-stage kidney disease.
A team of scientists reveals that microRNAs (miRNAs) can be secretly packaged by cells and delivered to target cells, regulating their functions. This discovery expands our understanding of miRNA's role in mediating intercellular/interorgan communication.
Researchers found that social interaction and a richer living environment significantly reduced tumor mass and volume in mice with cancer. The study suggests that low-stress, mentally stimulating environments may be beneficial for cancer treatment.
Researchers have discovered a connection between giant gas clouds and the formation of active galactic nuclei, which power the bright centers of some galaxies. The study suggests that gas clouds can either be consumed by supermassive black holes or give birth to new stars, leading to increased activity.
A 30-minute massage on cervical trigger points improves autonomic nervous system regulation in patients with chronic tension headaches. This leads to a better psychological state and reduced stress and anxiety. Patients also report relief from symptoms within 24 hours after the massage.
The European Society for Medical Oncology (ESMO) has published updated clinical practice guidelines for cancer care, providing vital information on diagnosis, treatment plans, and follow-up. The new guidelines cover various tumor types and include expanded sections on cardiotoxicity and fertility considerations.
Researchers found a compound called P7C3 that improves newborn neuron survival and reduces programmed cell death in the brain's memory hub. This discovery offers new hope for treating Alzheimer's disease by targeting the underlying neuroprotective mechanism.
Researchers found that ferns in the northern end of the redwood forest ecosystem are better equipped to absorb fog water than those in the southern region. This has important implications for the structure of plant communities and how ecosystems function during drought periods. The study suggests that native ferns may be able to acclim...
Median incomes for U.S. IEEE members in electrotechnology and information technology increased by 4.9% to $116,000 in 2008, more than doubling the previous year's rise of 2.4%. The survey results provide valuable insights for employers seeking to attract and retain skilled professionals.
Tulane University will establish an International Center of Excellence in Malaria Research for West and Central Africa, aiming to achieve malaria control in the region. The seven-year project will involve 48 investigators from 10 institutions, including four African partners.
A community-based study found HPV DNA testing to be over 50% more sensitive than cytology testing for detecting precancers and cervical cancers. The study involved 50,000 women and revealed a significant reduction in precancer rates among HPV DNA-positive women.
Researchers at UT Southwestern Medical Center discovered a compound called P7C3 that preserves newly created brain cells and boosts learning and memory in animal studies. The study found that P7C3 protects newborn neurons from dying, restoring normal structure and function of the hippocampus in knockout mice.
Researchers discovered an alternative form of evolution that helps Drosophila flies defend against nematode parasites. This finding has significant implications for developing treatments for serious human diseases like river blindness.
A study of 1,329 healthy children found that approximately one in five will have a psychiatric disorder with impairment upon entering formal schooling. Sociodemographic risk factors such as poverty and limited parental education were associated with an increased risk of mental health issues.
An international team of scientists studied two Sumatra earthquakes, finding differences in sediment composition between the rupture areas. This difference may have contributed to a larger tsunami in the 2004 event, highlighting the potential for high tsunami hazards in this region.
Researchers developed a technique to isolate specific cancer proteins using a synthetic nanopolymer. The polymer-based metal-ion affinity capture (PolyMAC) method isolated phosphorylated proteins, which are highly associated with cancer, from a sea of other proteins. This breakthrough may aid in the development of new cancer drugs.
Researchers at the University of Pittsburgh School of Medicine have identified a biochemical pathway regulating blood pressure, involving nitric oxide signaling and proteins thrombospondin-1 (TSP1) and CD47. Blocking this pathway could lead to novel blood pressure-regulating drugs.
A new study found that patients with hypertension who monitor their blood pressure at home and adjust their medication can experience greater falls in blood pressure. The TASMINH2 trial showed significant reductions in systolic blood pressure after 6 months, with no increase in side effects.
Scientists at Johns Hopkins University create method for pinpoint delivery of molecules to individual cells, enabling targeted cancer treatment. The technique uses gold nanowires coated with tumor necrosis factor-alpha, which triggers specific cellular responses without affecting surrounding cells.
Barrow scientist A.D. Bud Craig is leading the global conversation about the insula, a hidden lobe of the brain involved in virtually every human emotion and behavior. The latest research indicates that the insula plays a crucial role in conditions such as addiction, anxiety, depression, and schizophrenia.
NASA's six-week GRIP mission will study the creation and rapid intensification of hurricanes, analyzing factors such as cloud droplet concentrations, air temperature, and wind speed. The mission aims to better understand how tropical storms form and develop into major hurricanes.
A genetically reprogrammed herpes virus and an anti-vascular drug combination shrinks spreading distant sarcomas in mice, with significant tumor reduction and improved survival rates. Researchers achieved these results by using the virus systemically via injection, overcoming a major stumbling block in previous cancer treatments.
Research features standardized approaches to measure and compare tumor size in lung cancer. The use of precise quantitation tools may allow for more rapid evaluation of the success or failure of drug candidates in clinical trials.
Researchers at UMass Medical School have discovered a new DAF-16 isoform that collaborates with other isoforms to regulate longevity and stress response in C. elegans. The newly found isoform, DAF-16d/f, works in concert with DAF-16a to promote organismal life span.
Researchers at Gladstone Institutes establish a connection between brain circuits and Parkinson's disease symptoms, identifying a potential treatment strategy. By activating specific pathways, they can mimic Parkinson's-like symptoms and even restore motor function in mice with dopamine deficiency.
A study found that genetic ancestry data correlates to physiologic measures, providing new evidence for personalized medicine. The research used genetic tools to estimate individual genetic ancestry and found a significant association between ancestry and lung function.
A decline in international medical graduates is creating a shortage of general surgeons, threatening patient access to quality surgical care. The study found that rural areas are particularly affected, with a 40% decline in the number of rural surgeons and a projected shortage of 1,875 general surgeons by 2020.