Researchers have identified specific brain areas that interact to compute confidence in decisions, allowing individuals to assess their choices. The study used fMRI to measure activity in the brains of volunteers while they made food choice decisions.
Researchers have made significant breakthroughs in optimizing stem cells and transplant approaches to treat patients with blood disorders. A new study has shown that the addition of vorinostat to standard therapy can safely reduce the incidence and severity of graft-versus-host disease, a life-threatening complication associated with h...
A new study by Nayuta Brand and Michel Chapuisat found that queen sweat bees restrict the amount of food provided to their first brood, resulting in smaller female workers. This 'choosing' behavior ensures that daughters become workers rather than queens.
Researchers block DNA repair pathway in leukemia stem cells by targeting protein RAD52, which is crucial for fixing genetic mistakes. This approach may lead to a new strategy to overcome drug resistance in cancer patients.
Researchers found high concentrations of gold in termite mounds, indicating a larger deposit underneath. These insects bring up small particles containing gold from the deposit's fingerprint and stockpile it in their mounds.
A new study finds that a reduced intensity conditioning regimen before marrow transplant significantly boosts disease-free survival rates among older AML patients. With a rate of 39%, this approach outperforms traditional methods in preventing relapse and improving patient outcomes.
Researchers present promising results from a Phase II study on quizartinib, a targeted therapy that may turn treatment-resistant leukemia into manageable conditions. The study shows great potential in turning fatal disease subtypes into chronic conditions with regular treatment.
Exposure to second-hand smoke significantly increases the risk of invasive meningococcal disease in children, with doubled risks at home and tripled risks for those born to smoking mothers. The study estimates an extra 630 cases of childhood invasive meningococcal disease per year.
Researchers report success of gene transfer therapy to turn patients' immune cells into cancer-fighting weapons. Three patients remain in full remission over two years after treatment, marking first successful demonstration of the approach.
A Phase II clinical trial found that over a third of high-risk leukemia patients responded to the experimental new drug quizartinib, experiencing complete remission and potentially life-saving bone marrow transplants. Many participants who did well with the drug had failed to respond to prior therapies.
In pre-clinical experiments, Angiocidin reduced acute myeloid leukemia (AML) cells by almost two-thirds, demonstrating its potential as a safer treatment alternative to standard-of-care chemotherapy agents like Ara-C. The protein also stimulated maturation in affected white cells, causing them to behave like normal cells.
Researchers at Children's Hospital of Philadelphia use bioengineered T cells to destroy leukemia cells, achieving a complete response in a 7-year-old girl. The treatment, known as CTL019, also stimulates an immune response and can be combined with immunomodulating drugs to reduce side effects.
A team of researchers at Georgia Institute of Technology has developed a low-temperature method to dope graphene films using self-assembled monolayers. This technique allows for the creation of p-n junctions with minimal disruption to the material's lattice structure and significant electron/hole mobility.
A new class of drugs has been shown to reduce the risk of graft-vs.-host disease, a deadly side effect of lifesaving bone marrow transplants, by half. The study used vorinostat, a cancer drug with anti-inflammatory effects, and found it safe and tolerable for patients undergoing reduced-intensity bone marrow transplants.
Scientists at UCSF have identified a specific nerve cell subset and protein called NOMPC responsible for sensing gentle touch in fruit flies. The discovery sheds light on the fundamental sense of gentle touch and its role in human experience.
Researchers have identified two strains of Clostridium difficile responsible for the global epidemic, highlighting the ease and rapidity of transmission across continents. The study shows that fluoroquinolone resistance played a key role in the spread of these strains.
A new study found that playing violent video games for three consecutive days led to increases in aggressive behavior and hostile expectations. In contrast, players of nonviolent games showed no significant changes. The study suggests a cumulative effect of repeated exposure to violent games on aggression.
Researchers at Emory University School of Medicine have obtained a detailed molecular picture that shows how glucocorticoid hormones shut off key immune system genes. The finding could help guide drug discovery efforts aimed at finding new anti-inflammatory drugs with fewer side effects.