A Northwestern University study finds that having a purpose in life is associated with improved sleep quality, reduced sleep apnea, and restless leg syndrome in older adults. The research suggests that cultivating purpose through mindfulness therapies could be an effective drug-free strategy to improve sleep.
Scientists from the University of Plymouth have discovered that cellular prion protein is over-produced in schwannoma cells, contributing to tumor growth and patient prognosis. The study identified existing drugs that could manage this protein overproduction and potentially lead to an effective therapy for neurofibromatosis 2 patients.
A study reveals that individuals with Complex Regional Pain Syndrome (CRPS) process visual information from the affected side of their body more slowly than the unaffected side. This suggests a possible change in brain mechanisms that normally allow us to process information at different locations.
Researchers developed FAST - a fast whole-brain imaging system that can visualize individual cells and subcellular structures in the entire brain. This technique allows for faster comparison of multiple brains to gain new insights into brain diseases.
Researchers at Osaka University have developed a new catalyst for amide hydrogenation that operates under mild conditions, allowing for the efficient conversion of amides to amines. The catalyst enables sustainable pharmaceutical production with minimal by-products and high selectivity.
Researchers from Virginia Tech and University of Pittsburgh School of Medicine have developed a new method to study the role of biomechanical forces in diseased pathologies. The technique, called nanonet force microscopy (NFM), measures single cell-fiber forces under both passive conditions and disease conditions.
Researchers discovered that endothelial cells lining blood vessels are not as effective at removing invading bacteria via xenophagy, a process used by epithelial cells. The study suggests that targeting the ubiquitination pathway could lead to new approaches for fighting infections like GAS.
Researchers at KAUST have developed a systematic method for comparing the accuracy of different types of simulation models for predicting extreme events. The study found that nonparametric methods are more flexible but limited to small dimensions, while parametric methods can handle higher-dimensional problems but are sensitive to errors.
The study sheds light on the functions of sweat gland components, revealing key roles for myoepithelial cells and nerve interactions. The findings have implications for treating disorders of the perspiratory system and could lead to new treatments for heatstroke.