Researchers at MIT have developed a continuous manufacturing process to produce long strips of high-quality graphene. The team's results are the first demonstration of an industrial, scalable method for manufacturing high-quality graphene suitable for membrane applications.
A new neuropathy measurement tool has been developed and found effective in quantifying symptoms and treatment efficacy. Minor revisions can improve its validity and universality for adoption in clinics and research settings.
The study reveals that a slight change in the substrate can practically stop an enzyme reaction. Computational design of a new variant was successfully produced and tested, demonstrating the method's accuracy and potential for future research.
Researchers uncover how bacterial 'gene swapping' fuels emergence and spread of infectious diseases, including antimicrobial resistance crisis.
The USPSTF recommends exercise, such as supervised classes and physical therapy, for adults 65+ at increased risk of falling. This intervention can help prevent falls-related injuries and deaths among older adults.
The Brazilian chip SAMPA will upgrade the detection system in ALICE at the Large Hadron Collider, enabling the detection of thousands of particles per second. The new system will increase the collision rate by a factor of 100, from 500 to 50,000 collisions per second.
Lehigh University has launched a long-term collaboration with the National Synchrotron Light Source II at Brookhaven National Lab to explore cutting-edge materials and biomedical research. The partnership aims to foster collaboration among researchers from academia, government labs, and industry.
Researchers present studies on community health workers using mini-malaria clinics and new bednets, finding high treatment success rates. Alternative solutions, such as insecticide-treated housing and blankets, are also being explored to fight malaria in conflict zones.
A new migraine treatment, erenumab, has shown significant promise in reducing headache frequency by over 50% in nearly a third of participants. The study found that erenumab reduced monthly migraine headaches by more than 50% for those who had tried up to four other preventative treatments without success.
The US FDA approved the combination of ipilimumab and nivolumab for metastatic kidney cancer patients. The treatment led to a 37% improvement in survival compared to sunitinib and durable responses in 42% of patients.
A study published in the Genes & Development journal reveals that tumor cells can survive even without Ras genes if Erf is also lost, casting doubt on the effectiveness of potential treatments. The researchers found that eliminating ERF allows mouse stem cells to grow and differentiate in the absence of RAS genes.
A new bacterial species, Listeria costaricensis, has been identified in Costa Rica, increasing the knowledge of Listeria's pathogenic potential. The discovery was made through a three-year research project that sampled water from an industrial drainage area, revealing the biodiversity of Costa Rican soils.
A line of strong storms, including an EF-2 tornado that killed one person and a tornado near Lynchburg, Virginia, were captured by NASA's GPM. The storm system was spawned by a deep trough of low pressure west of the Appalachians.
Researchers deciphered the chemistry behind lithium fluoride's formation in SEI, discovering a new method to monitor hydrogen fluoride concentration. This monitoring capability is crucial for future basic science studies and commercial applications.
Regular testing and treatment of pre-school children for snail fever could reduce the spread of the disease while promoting childhood health and development. Infected children can develop symptoms within three months and may experience stunted growth, learning difficulties, and increased risk of malnutrition.
Researchers at UC San Diego have developed a gene drive system targeting the invasive spotted-wing drosophila, a fruit fly causing millions of dollars in damage. The Medea system dramatically biases inheritance rates with near-perfect efficiency, allowing for potential control of populations.
Researchers analyzed 40,000 speeches from the National Constituent Assembly to track word-use patterns and find that the revolution's principles emerged and evolved over time. Committees played a significant role in proposing and disposing legislation, reducing the effectiveness of charisma in direct debate.
A new study found that microgravity during spaceflights has a more significant negative impact on skeletal muscle than low oxygen environments. Researchers suggest that therapeutic and rehabilitative interventions should focus on correcting inactivity rather than hypoxia.
Researchers at MIT's CSAIL have developed RoadTracer, an automated method to build road maps that is 45 percent more accurate than existing approaches. The system uses data from aerial images and creates maps step-by-step, tracing out roads one step at a time.
At the American Physiological Society's President's Symposium Series, top researchers discuss the biology and pathophysiology of exosomes, as well as their use in diagnostic and therapeutic tools. Exosome expert Leland Hartwell concludes the series with a Nobel Prize lecture on the importance of lifelong learning.
Researchers found that a transcription factor protein called Runx3 plays a critical role in directing T cells towards memory cells, which can live for decades. This discovery may lead to the development of drugs that improve immune responses to vaccines and treatments for chronic diseases such as cancer.
The American Physiological Society honors four distinguished physiologists with Distinguished Lectureships. Ole H. Petersen presents on pancreatic physiology and pathophysiology, while Yatrik M. Shah discusses oxygen sensing pathways and their link to cancer. Merry L. Lindsey shares her top five mentoring tips in her lecture.
Scientists at Ruhr-University Bochum successfully converted CO2 into an alcohol through a two-step reaction, facilitated by copper and rhodium catalysts. The process achieved a 40% recycling rate for the base, paving the way for industrial-scale applications.
Researchers at IRB Barcelona have found covalently linked beta-amyloid dimers in the brains of patients with Alzheimer's disease. These dimers are preserved during tissue extraction and could serve as new biomarkers for early detection.
Scientists have developed a method to modify graphene without destroying it, creating a stable structure called 'polymer carpets'. When exposed to light, these carpets generate current, making them suitable for use in solar batteries and flexible electronics.
A recent study published in Communications Chemistry found that tungsten accumulates in specific regions of the bone, particularly in bone marrow and cancellous bone tissue. This accumulation raises concerns over the element's safety for human exposure, especially among young individuals.
A new study found that scientific models used to determine which species and habitats to protect lack critical information, leading to ineffective conservation efforts. The research highlights the need for more accurate species distribution models to target conservation efforts in areas with the most impact.
PolyU has won several prizes at the International Exhibition of Inventions of Geneva, including the Grand Prize for its Defocus Incorporated Multiple Segments (DIMS) Spectacle Lens for Myopia Control. The lens can slow down myopia progression in children by 60% and provides clear vision.
The University of Surrey has developed a new algorithm that can compress large amounts of data from bridge monitoring systems, reducing the storage requirements for authorities. The K-SVD method achieves near-lossless reconstruction with less than 0.1% data loss, compared to other methods which require up to 50% of the original data.
Research reveals huge variation in gluten-free food prescribing practice in England, with the most deprived areas having the lowest rates. The study found that factors such as clinical commissioning group policies and deprivation levels play a significant role in determining prescribing patterns.
Geneticists at Martin Luther University Halle-Wittenberg deciphered a central signalling pathway that encodes and controls the synchronisation of multiple processes during germ cell development in C. elegans. This process involves RNA-binding proteins and a MAP kinase signalling pathway, optimising germ cell production.
The project, led by Pacific Northwest National Lab, aims to develop a new method for producing and harvesting seaweed for biofuels. The team plans to deploy a three-mile-long recycled carbon fiber cable adrift in the open ocean to cultivate macroalgae.
A Chapman University study reveals men are more likely to punish others to advance their interests. The research found that men will impose greater costs on others and destroy groups to rise in the hierarchy.
Naloxone has been shown to reduce brain inflammation and improve neurological function in rats after a stroke, with a potential new treatment avenue for stroke patients. Further study is warranted to investigate naloxone's effectiveness in humans.
Research suggests that bone cells can release signals driving prostate cancer progression and growth, especially when cancer metastasizes to bone. A study found that inhibiting BMP signaling in myeloid cells could restrict cancer cell production and tumor growth.
Endocrine-disrupting chemicals like DES can cause developmental effects in mouse seminal vesicles, affecting gene expression and DNA methylation. The study also reveals that estrogen receptor alpha plays a key role in mediating these effects.
Janardan K. Reddy, a world-renowned pathologist, has been awarded the ASIP Gold-Headed Cane Award for his significant research contributions to liver biology, particularly peroxisomes and carcinogenesis. He is also recognized for his exceptional teaching and mentoring skills.
The Technical University of Munich (TUM) has developed an adaptive algorithm called ALES+, which can accurately measure sea levels in both open and ice-covered ocean areas. This improvement enables researchers to track changes in sea level and ocean currents, crucial for understanding climate change.
Researchers at Karolinska Institutet have created a new disease model for neurodegenerative diseases like ALS and MS using the TGF-β protein. This model shows that monocytes can transform into microglia-like cells in response to TGF-β, which could lead to the development of new immunotherapies for these devastating diseases.
Michigan State University researchers discovered that having a blended mix of married and unmarried bandmates boosts creative success and innovation. Similarly, MBA students benefited from marital diversity, with its impact growing over time. This study highlights the benefits of lifestyle diversity in various groups.
A NYU Dentistry study found that a comprehensive cavity prevention program with primary and secondary prevention strategies significantly lowers the rate of new and untreated cavities compared to traditional molar sealant programs. Both school-based programs reduced the risk of untreated decay over time.
Researchers at the University of Basel have developed a method to generate stable cartilage tissue from adult human mesenchymal stem cells by inhibiting specific signaling pathways. This breakthrough has significant implications for the treatment of joint diseases and injuries.
The British Journal of Pharmacology has published updated guidance for authors on designing experiments, analyzing data, and presenting results. The editorials aim to improve reproducibility and transparency in preclinical research by providing approaches to data presentation and checklists for immunoblotting and immunohistochemistry.
Researchers have discovered a way to create superconducting materials that carry 'spin' currents, improving efficiency in high-performance computing. By aligning electron spins, they can generate pure spin supercurrents, which could use significantly less energy than current silicon-based electronics.
A new study found the Epstein-Barr virus is linked to seven serious diseases, including systemic lupus erythematosus (SLE), multiple sclerosis (MS), and type 1 diabetes. The virus affects nearly 8 million people in the US, highlighting a common cause of chronic illness.
The anthology explores dementia-associated apathy research, neural system effects on late-life depression, and adopting new models of care. It also proposes solutions to accelerate change in science, practice, training, and public policy.
A multicenter database study of adults undergoing spinal deformity surgery found that daily opioid users had longer ICU stays and more severe postop disability compared to non-opioid users. The study highlights the need for preoperative counseling and alternative pain management strategies for patients at risk of daily narcotic use.
A study found that tumors may overcome immunotherapy by increasing TIM3 and regulatory T cells, which inactivate immune killer T cells. Adding a TIM3 inhibitor to radiotherapy/immunotherapy increased response duration, but tumors still relapsed. Researchers also discovered that Tregs contribute to cancer regrowth.
Researchers at Indiana University have discovered a new and potentially toxic flame retardant, TTBP-TAX, in the environment. The chemical was found in dust and air samples from an electronic waste facility and 70% of household dust samples collected from homes in Bloomington, Indiana.
A systematic review of 49 randomized trials involving 23,098 participants found that various self-regulation interventions were effective in promoting emotional control, social skills, and learning. The review suggests that these programs can help maintain health and well-being throughout life.
Researchers found that combining anti-CTLA-4 and anti-PD-1 immunotherapies enhances response rates and generates more memory T cells, leading to better tumor control. This combination may help prevent relapse in patients with therapies targeting CTLA-4 and PD-1 checkpoints.
A study by Sina Esteky found that people at higher elevations are more willing to take financial risks and engage in sensory risks. This effect is subconscious and disappears when participants are informed or unable to see their floor level.
Research found that having an evening preference is linked to a higher BMI among people with Type 2 diabetes. Participants with late breakfast times had a BMI of 28.4 kg/m^2, compared to those who ate earlier, who had a lower BMI by 0.37 kg/m^2.
A recent study found that women are consistently less intensively treated with high-intensity statins after a heart attack, even when prescribed, and across various patient characteristics. This underutilization can lead to preventable vascular events, emphasizing the need for clinicians to communicate the benefits of these medications.
A new study from Stockholm University shows that prescribed burning in southern Ethiopia's tree heather heathlands maintains biodiversity and habitats for alpine plant species. The practice, which has been used for at least 2000 years, is recommended to be maintained but regulated to protect local ecosystems and societies.
A Portland State University research team published an interactive diagram and web-based presentation in Frontiers in Neurology, revealing the complex nature of mild traumatic brain injury (TBI). The causal-loop diagram shows how specific variables interact to influence concussion recovery.
Researchers at Lund University discovered a new approach to treat severe epilepsy by targeting a specific brain area, reducing seizure activity. This breakthrough method, using chemogenetics, may pave the way for improved treatment options for thousands of people in Sweden affected by the disease.
Researchers at the University of Copenhagen have identified a new protein shield called Shieldin that helps repair damaged DNA and affects resistance to PARP inhibitor drugs used for breast cancer treatment. This discovery may contribute to making decisions for treating cancer patients and understanding mechanisms of resistance.
Researchers at Duke University Medical Center have developed man-made aptamers that target prostate cancer cells, killing them while leaving healthy tissue unscathed. The findings suggest that these molecules could form the basis of new cancer therapies if further studies bear out.
Researchers used single-cell imaging to study how melanoma cells evade drug action and acquire resistance to BRAF-inhibitor dabrafenib. The study found that 10% of treated cells reactivated the MAPK signaling pathway within 2-3 days, allowing them to signal through the pathway even in the presence of BRAF inhibition.