Researchers propose a practical approach to understanding interplay between social and ecological spheres using causal chains. Causal chains can help break cycles of degradation and promote sustainable development goals.
A randomized trial of PHAT Life, a role-playing intervention, found that teens on probation reported a reduction in number of sexual partners and an increase in consistent condom use. The program showed promise in reducing sexual risk-taking among high-risk youth.
Researchers found that Zika virus infection causes death of glioblastoma cells, a common and aggressive type of brain tumor. The study suggests that genetically modifying Zika virus to produce the digoxin molecule could be an alternative treatment for glioblastoma.
Researchers found that the northern Galápagos Islands have been warming by almost 0.4 degrees F per decade, with temperatures increasing overall by about 1.1 degrees F since the 1970s. This finding is significant because it suggests that the region's reefs are more vulnerable to climate change than previously thought.
Researchers propose that cave art may have played a role in the development of human language, citing acoustic properties and visual representations. The study suggests that early humans used sound echoes to convey symbolic thinking, which eventually led to the creation of language.
Researchers found that mature cells in different organs activate the same genes and undergo similar processes when dividing again, leading to potential new targets for cancer treatment. This discovery could support using universal strategies to treat or prevent cancer in various organs.
The Russian National Technological Initiative aims to intensify heat transfer using nanomodified composite materials and nanostructures, aiming to remove high-density heat fluxes at low temperature differences.
A total of 1.8 million young people between ten and 24 years old are estimated to develop tuberculosis (TB) annually, with 20-24-year-olds at the greatest risk. Young adults with TB may face disruptions in education, employment, or family responsibilities due to their illness.
The Clinical Epidemiology Database aims to facilitate collaboration among researchers by providing a standardized platform for accessing and exploring complex clinical data. The database, launched by the University of Pennsylvania, introduces an intuitive interface and provides documentation of study design and background.
Researchers identified elevated tissue iron as a critical factor in fungal infection risks for lung transplant recipients. Elevated iron levels prompted Aspergillus invasion into transplanted tissue, suggesting a potential new approach to curb these life-threatening infections.
A team of researchers developed a soft robot that uses kirigami to achieve locomotion, gripping the ground like snakeskin. The robot's surface transforms into a textured surface as it stretches, allowing it to crawl without rigid components.
Researchers used fMRI to study brain activity while watching Memento, finding repeating patterns in the brain that correspond to key scenes. These 'neural fingerprints' help viewers piece together the storyline, revealing insights into how the brain processes narratives and memory.
Researchers discovered that glial cells increase the acidity of the extracellular environment when exposed to ATP, leading to a massive release of acid. This triggers a feedback loop that prevents over-excitability of neurons by inhibiting neurotransmitter release.
Dr Gisela Kopp, a biologist at the University of Konstanz's Max Planck Institute, will receive a five-year fellowship to explore unusual research questions and new avenues of thought. The award aims to support early career researchers from MINT disciplines with innovative and interdisciplinary approaches.
A study published in PNAS found that a protein called neuregulin 3 suppresses the release of glutamate, a neurotransmitter essential for learning, in people with schizophrenia. The researchers used genetic and biochemical techniques to investigate how neuregulin 3 controls neurotransmitters in the brain.
Research by Candice Odgers highlights both positive and negative uses of smartphones among teens. While moderate usage is linked to no negative impact on mental well-being, increased screen time among low-income teens correlates with more physical fights, arguments, and school troubles.
Researchers used historic and modern plant genomes to measure the rate of evolution in a wild plant. They found that Arabidopsis had been introduced to North America by Europeans around 1600, with new mutations appearing over the past 400 years. These findings provide insights into the genetic paradox of invasion.
The NIH has released datasets for rheumatoid arthritis and systemic lupus erythematosus disease tissue, providing clues about potential research targets. Researchers can access the data to explore new approaches to understanding autoimmunity and developing medicines.
A UTSW study found that inhibiting glucagon action has potent anti-diabetic effects, reducing negative fat tissue impacts and improving cardiac function. The research may advance understanding of diabetes drugs' benefits for heart health.
Researchers have discovered how Xanthomonas bacteria manipulate nutrient supply and hormonal balance in plants. The study found that a specific protein, XopH, targets phosphorus supplies inside plant cells, weakening plant defences and allowing bacteria to multiply.
A new study on attacker motives identifies successful phishing strategies, including authoritative tone and shared interest, which can be used to develop detection tools. The study also found that incentives, such as quicker and larger rewards, motivate attackers to apply more effort in constructing persuasive emails.
Scientists at Whitehead Institute have developed a modified CRISPR/Cas9 system to remove methylation tags from the FMR1 gene, restoring its expression and rescuing neurons from fragile X syndrome. This approach may prove useful for other diseases caused by abnormal methylation.
The international team's roadmap outlines research directions to boost human radioresistance through gene therapy, radioprotective mechanisms, and regenerative technologies. This could extend the healthspan of spacefarers and enable safe long-term space colonization.
Scientists have developed CONTISOL, a solar reactor that can run day and night using concentrated solar power. The reactor uses air as the heat transfer medium and achieves stable temperatures round the clock.
Researchers found that a simple walking test can accurately diagnose idiopathic normal pressure hydrocephalus (iNPH) and progressive supranuclear palsy (PSP) by assessing participants' gait while performing dual tasks. The study revealed that the test improved diagnostic accuracy to 97% when combined with other assessments.
The study confirmed two major migrations through southeastern Europe, with early farmers from Anatolia spreading westward and a steppe population replacing northern Europe's population. The region remained a genetic contact zone between East and West until the Bronze Age.
Researchers at the University of Michigan discovered that fruit flies use external temperature to regulate their sleep cycles, which may provide insights into human sleep patterns. Mild changes in temperature have physiological effects on clock neurons that control sleep timing.
Researchers create a new approach to machine learning using a single-layer neural network that can analyze images with limited training data. The algorithm, called MS-D, requires far fewer parameters than traditional methods and has the ability to learn from a remarkably small set of images.
The Estée Lauder Companies presents research on new anti-aging compounds, including hydroxypinacolone retinoate (HPR) that improves skin appearance without irritation. Caffeine enhances epidermal hydration by increasing the transepithelial electric potential and electro-osmosis.
A team of researchers from Ruhr-University Bochum has discovered that the bacterium Streptomyces chartreusis produces 1,044 different substances, exceeding expectations. Many of these substances have pharmaceutical potential and could lead to new treatments for patients who suffer from iron overdose or aluminium toxicity.
Researchers at UNC and NC State developed a biodegradable hydrogel scaffold system to release combination chemo-immunotherapeutic drugs, significantly inhibiting cancer recurrence after primary tumor removal. The approach could work in other tissue types and has shown promising results in animal models.
A new study using ancient DNA analysis has found that human populations have been migrating and mixing extensively throughout history, with the Yamnaya people from Central Asia expanding rapidly to Europe, Britain, and beyond. The research also reveals a biased genetic exchange between farmers and hunter-gatherers in northern Europe.
Researchers created a composite material combining natural rubber with nanocarbons derived from compost, demonstrating improved electrical resistivity and potential applications as sealants and sensors. The study provides an eco-friendly alternative to carbon black fillers, which are commonly used in rubber products.
A UT Dallas team has addressed a long-standing problem in scanning tunneling microscopes, preventing tip crashes that can damage samples and forfeit valuable time. The breakthrough enables atomically precise manufacturing, leading to innovations in materials science, medicine, and computing.
Computer scientists and materials researchers developed a more accurate and objective method for classifying steel microstructures. The method uses machine learning to analyze microscope images and achieve accuracy of around 93%, surpassing conventional methods which only achieved 50% correct classification.
A phase 1/2 trial of larotrectinib found that three-quarters of patients with advanced cancers responded to the treatment, which targets a specific genetic mutation. The therapy has shown promise in treating pediatric patients with TRK-positive cancer, including infantile fibrosarcoma, and offers a potential cure for some cases.
Researchers discovered five new regions in the human genome associated with increased pancreatic cancer risk, including variants in genes that regulate cell growth and tumor suppression. The findings may lead to more targeted treatments and early detection screening for pancreatic cancer.
A new study by Queen Mary University of London aims to develop a 'beetroot pill' that could reduce the risk of kidney failure in patients undergoing coronary angiography. The research seeks to harness the antioxidant properties of dietary nitrate found in beetroot to prevent contrast-induced nephropathy, a common complication of the pr...
Researchers used CT technology to scan 13 Tasmanian tiger joey specimens, creating high-resolution 3D digital models that reveal the species' growth and development. The study sheds light on the evolution of the Tasmanian tiger's unique appearance, which resembles that of dogs and wolves.
A new study shows that a creative couples' intervention significantly improves communication in people with Alzheimer's and their caregivers. The 10-week program increased facilitative communication in caregivers and sociable communication in care receivers, leading to better understanding, intimacy, and reduced conflict.
A study found a strong correlation between midwife integration and better birth outcomes, with higher rates of vaginal births and breastfeeding. States with high midwife integration, such as Washington and Oregon, had lower rates of premature births, cesarean deliveries, and newborn deaths.
Physicist Andrea Pocar and his team at UMass Amherst designed a key part of the DarkSide-50 detector, achieving high sensitivity in detecting WIMPs. The detector's double-phase argon technique shows promise in searching for low-mass WIMPs.
A study found that e-cigarette heating coils release potentially hazardous levels of lead and other toxic metals into the aerosols vapers inhale. Chronic exposure to these metals can cause lung, liver, immune, cardiovascular, and brain damage, as well as cancer.
Two novel ocular hypotensive agents, netarsudil and latanoprostene bunod, have been approved for use in humans, reducing intraocular pressure with lasting results. These breakthrough drugs also show promise for treating dry eye disease and delivering ophthalmic drugs via microneedles.
A study published in Food Chemistry shows that reducing water usage for cherry tomato crops by 50% maintains quality and increases carotenoid levels. This technique can be applied to other crops, offering a sustainable solution for farmers and consumers.
Researchers are developing synthetic antimicrobial materials that target toxic bacteria while being biocompatible with healthy mammalian cells. The goal is to create new therapeutic platforms to combat multidrug-resistant bacterial infections.
Clemson University researcher Suyi Li is investigating how origami can be used to create new materials, including floor pads and building foundations that absorb vibrations in earthquakes. His work could lead to the development of new technologies with a range of applications.
A novel 'memtransistor' device developed by Northwestern University's Mark C. Hersam can process information and store memory like the human brain, potentially revolutionizing computing. The memtransistor combines characteristics of a memristor and transistor, operating with multiple terminals similar to neural networks.
A new U.S.-wide report card ranks all 50 states on their maternity care quality, revealing a strong connection between midwifery integration and improved birth outcomes. States with high midwifery integration scores tend to have lower rates of premature births, cesarean deliveries, and newborn deaths.
A recent study published in the Journal of Thrombosis and Thrombolysis found that prolonged TV viewing increases the risk of venous thromboembolism, a potentially fatal condition. The research, which analyzed data from over 15,000 Americans, suggests that even regular exercise is not enough to offset the risks of sedentary behavior.
The new smart contact lens can detect glucose levels in tears using built-in pliable electronics and wireless antenna. It offers a pain-free way to measure blood sugar levels, potentially reducing compliance issues among diabetic patients.
The studies reported an overall response rate of 75 percent for patients ages four months to 76 years with 17 different cancer diagnoses. Larotrectinib had rapid, potent, and durable anti-tumor activity in children and adults with solid tumors and TRK fusions.
Researchers developed a high-resolution nanometer-scale magnetic resonance imaging (MRI) technique, enabling unprecedented views of biological systems. The new method extends traditional MRI capabilities to the nanoscale, providing insights into Parkinson's and Alzheimer's diseases.
Under projected rates of sea level rise, Pacific coast tidal wetlands face devastating loss, with high- and mid-marsh habitats projected to be lost by the end of the century. Only low marsh habitats are likely to survive, even in California and Oregon.
A new study by Brigham and Women's Hospital researchers identifies a novel biomarker for coronary heart disease in women, oxidized lipids that are not associated with traditional risk factors. Women with the highest levels of this marker are 4 times more likely to develop CHD over several years.
A recent study suggests that lay-health workers can significantly reduce hospital readmission rates for high-risk patients after surgery. The study found a 47.7% relative reduction in 30-day hospital readmissions and a 56% decrease in odds of being readmitted within 30-days.
Research reveals that individuals with Alzheimer's disease who die from the condition itself tend to have less hospitalization and ICU stays compared to those who die from other causes. This contrasts with those who receive fewer palliative care services during their final months.
Scientists at Ecole Polytechnique Fédérale de Lausanne have created a method for tracking specific enzymes in cell compartments, helping identify their roles in various cancers. The biosensors reveal compartment-specific distributions of bioactive enzymes, which may aid the development of targeted cancer treatments.
A new study by Potsdam Institute for Climate Impact Research found that delaying global CO2 emission peak by five years between 2020 and 2035 could result in an additional 20 cm of sea-level rise by 2300. The researchers used a combined climate-sea-level model to analyze the impact of delayed mitigation on global sea-level rise.
Researchers found that social role, not causal influence, determines blame distribution in real life. The study tested this assumption in an online experiment with 209 test participants and found that bosses received more criticism than employees even when they didn't make the decision.