A study in mice suggests that altering the gut microbiome via prebiotics or probiotics may be a potential treatment for PCOS. The research found improvements in testosterone levels, ovulation, weight, and insulin resistance in mice with PCOS, linked to changes in gut bacteria composition.
Research suggests that sperm DNA damage in male partners may cause recurrent pregnancy loss (RPL), with affected men having twice as much DNA damage as healthy counterparts. High levels of reactive oxygen species were also found, which can damage cells like sperm.
A new study reveals that long-term opioid users are at risk of hormone deficiencies, including hypogonadism and hypocortisolism. Up to 65% of men using opioids long term have low testosterone levels, leading to symptoms such as erectile dysfunction and infertility.
Researchers have identified new pathways controlling inflammation in the gut and explored diet-based interventions to prevent C. difficile infections. Prebiotics may also help mitigate gastrointestinal toxicity from radiation treatment.
A recent study found that nearly one-fifth of first-time users of a new hybrid closed loop insulin pump stopped using the device due to difficulties meeting technical demands. Patients required calibration between their continuous blood glucose monitor and fingerstick blood tests, leading to frustration.
A large study published in The New England Journal of Medicine found that treating women with thyroid antibodies and normal thyroid function with Levothyroxine did not improve the chances of live birth. The study showed similar outcomes in both groups, with 56.6% and 58.3% becoming pregnant, respectively.
A large study led by the University of Birmingham found that treating women with normal thyroid function and thyroid peroxidase antibodies with Levothyroxine did not increase live-birth rates. The researchers suggested that previous recommendations to use Levothyroxine in these women may have been based on limited evidence.
A new study presented at ENDO 2019 found that the A1c test used to diagnose diabetes tends to underestimate its prevalence. The test missed detecting 73% of diabetes cases compared to the oral glucose tolerance test, highlighting its limitations.
A new study presented at the Endocrine Society's annual meeting suggests that eating later in the day is associated with a higher body mass index and greater body fat. The research used advanced technology to track participants' sleep, physical activity, and eating patterns over a week-long period.
Researchers found that older adults with type 1 diabetes spend more than an hour per day in the hypoglycemic range, increasing their risk of severe complications. This study highlights the need for interventions to reduce the risk of severe hypoglycemia in this age group.
A team of researchers from Tokyo Metropolitan University has demonstrated that the tunable hydrophobic nature of dense siloxane gels strongly correlates with their catalytic activity. The study shows that molecules with different hydrophobicity interact differently with surfaces, leading to increased or decreased catalytic activity.
A meta-analysis of 473 patients found that weight loss reduces headache frequency, pain intensity, and disability in obese migraine sufferers. Weight loss through bariatric surgery or behavioral intervention also shows significant improvements.
Transgender men undergoing testosterone therapy may retain their fertility potential even a year into treatment, according to researchers. The study found preserved ovarian function and unchanged hormone levels, suggesting well-preserved reproductive capabilities.
The Endocrine Society's Clinical Practice Guideline recommends simplifying medication regimens and tailoring glycemic targets to improve compliance and prevent complications in older adults with diabetes. The guideline prioritizes blood glucose targets over hemoglobin A1c tests, aiming to reduce cardiovascular disease outcomes.
Researchers at McMaster University have developed a method to create artificial tumours using magnetic 3D printing, enabling faster and more affordable testing of new treatments. The technique uses magnets to concentrate human cells in a predetermined area, forming 3D cell clusters that mimic human tissues.
A new study suggests that obesity may play a role in reproductive problems in women with type 1 diabetes. Menstrual irregularities were seen in 47% of those with the disease, and polycystic ovary syndrome (PCOS) was found in 14%, increasing the risk of miscarriages and stillbirths.
A study found that sleep quality decreases in the late luteal phase, just before menstruation, with less sleep efficiency, longer wake after sleep onset, and higher sleep fragmentation index. Caloric restriction also negatively affects sleep during this period.
Researchers have developed a new catalyst that can efficiently break down ammonia in the air, converting it into harmless nitrogen gas and water. The catalyst, made of gold nanoparticles on a metal oxide framework, is effective at room temperature and has been shown to reduce gases contaminated with ammonia to undetectable levels.
A new animal study suggests that exposure to dim light at night may contribute to the spread of breast cancer to bones. Researchers created a mouse model of bone metastatic breast cancer and found that mice exposed to a light/dim light cycle had larger tumors and increased bone damage compared to those in a standard light/dark cycle.
A study found that people with diabetes are at a higher risk of fractures, particularly among Caucasians and Hispanics. However, African Americans with diabetes showed little to no increased fracture risk compared to those without diabetes.
A new study by The Endocrine Society found that treating obstructive sleep apnea (OSA) with an overnight CPAP machine can result in more weight loss for adults with obesity who try to lose weight by restricting calories. Patients who received concurrent CPAP treatment lost an average of 5.7 pounds more than those who did not treat thei...
The study found that the percentage of younger women initiating bisphosphonate treatment decreased over the 12-year period, while older women and those with osteopenia or osteoporosis increased. The overall percentage of osteoporosis among white and Asian women also rose.