Researchers found that simultaneous ripple activity occurred in key parts of the brains of epilepsy patients before they recalled memories. The team also discovered that coordinated ripple synchronization triggered electrical activity patterns seen during learning and was associated with correct memory recall.
A recent study found that less than 10% of US doctors' treatment recommendations for heart patients are based on evidence from multiple large, randomized clinical trials. The majority rely on lower-quality data, with only 8.5% supported by Level A evidence.
Researchers discovered a way to regulate the beta-catenin-dependent Wnt signaling pathway using a chemically synthesized compound. The inhibitor reduces AAK1's frequency in endocytosis, blocking arbovirus invasion and potentially treating breast and cervical cancer.
Tropical Cyclone Idai is moving in a westerly direction after making landfall in Mozambique, affecting provinces of Zambézia, Sofala, Manica, Tete, and Inhambane with moderate to strong rains and severe thunderstorms.
Researchers from Virginia Tech and Eastern Washington University are collaborating on a $958,415 NSF grant to study the critical role of the honey bee gut microbiome in health and defense against parasites. The team aims to develop a network of genes from the parasite, microbiome, and host to determine their interactions with each other.
A study of nearly 5,900 older women found that light physical activity, even just 5.6 hours per day, may reduce the risk of coronary heart disease and cardiovascular disease. The researchers suggest replacing sedentary behavior with light physical activity supports previous guidelines.
A Yale study of over four million Medicare patients found that hospitalizations for heart attacks have declined by 38% since the 1990s, while the 30-day mortality rate has dropped to an all-time low of 12%. These gains are attributed to national efforts to prevent heart attacks and improve care.
Kate Smits' team is working with residents and local universities to find environmentally-friendly solutions that respect ancestral ways of life. The goal is to make artisanal and small-scale gold mining safer, cleaner, and more sustainable.
New studies show that catheter ablation is not more effective than drug therapy in preventing strokes and deaths from atrial fibrillation. However, patients who undergo the procedure experience significant improvements in quality of life and symptoms, including reduced hospitalizations and recurrences of the condition.
Researchers found that a repellent odor in a mixture specifically inhibits the perception of an attractive odor in vinegar flies, while geosmin activates only one specific glomerulus. This mechanism could help protect animals from contaminated food and potentially apply to humans as well.
Chronic periodontitis may increase the risk of developing dementia by 6%, according to a recent study published in the Journal of the American Geriatrics Society. The research suggests that preventing and treating periodontitis could lead to a reduced risk of dementia.
The study analyzed 271 genomes from the Iberian Peninsula and found that a group of steppe descendants replaced almost all men 4,000 years ago. The research team also discovered that Basque genetics have hardly changed since the Iron Age, with a high frequency of the Y chromosome R1b.
A recent study using big data analysis has found that catheter ablation is associated with a lower risk of stroke, death, and major bleeding in patients with atrial fibrillation. The research, led by Mayo Clinic, used a large cohort of patients to replicate the results of a clinical trial and provide complementary evidence for clinicians.
Researchers at GW Cancer Center discovered USP15 as a potential biomarker for treatments of breast and pancreatic cancers. The enzyme regulates homologous recombination repair and cancer cell response to PARP inhibitors.
Researchers at Stanford University have developed a new measurement technique that confidently shows the efficiency of quantum dots can compete with single crystals. This breakthrough could lead to the development of new technologies and materials requiring high semiconductor efficiency.
Researchers developed a method to design metamaterial structures with optimum thermal radiation performance, using machine learning and electromagnetic calculations. The new nanostructure demonstrated an exceptionally narrow thermal emission spectral band, exceeding conventional limits.
A University of Texas at Arlington nursing professor has been awarded $6.575 million in grants to combat debilitating musculoskeletal diseases such as sarcopenia and osteoporosis. His research aims to advance discovery of how aging leads to these conditions, with the goal of developing new diagnostics and treatments.
Researchers have discovered autoreactive cells in narcolepsy patients, providing new proof that the sleep disorder is an autoimmune disease. Autoreactivity was found not only in patients but also in healthy individuals, suggesting a trigger for the disease.
Two Boston University School of Medicine students have received a national award for their innovative project, which uses Uber Health to eliminate transportation barriers to healthcare access for urban OBGYN refugee women. The pilot study found significant decreases in patient no-show rates and improved patient satisfaction.
Tropical Cyclone Savannah is a low-pressure system strengthening in the Southern Indian Ocean. It will intensify to 80 knots before weakening over the next few days.
Researchers discovered that muscle stem cells produce proteins MyoD and Hes1 in an oscillatory manner, ensuring a sufficient supply of stem cells. This phenomenon is crucial for muscle regeneration and differentiation. The study aims to develop new therapies for muscular disorders by understanding the oscillation mechanism.
A study published in The Lancet Respiratory Medicine found that the composition of a child's nose microbiome is altered in cases of respiratory infections compared to healthy peers. This difference can predict disease severity, hospital stay duration, and likelihood of recovery without antibiotics.
Researchers at Lobachevsky University discovered that the electrophoretic mobility of red blood cells and buccal epithelium cell analysis can effectively assess stress response severity. These indicators reflect engagement of stress-implementing systems and immune system effectiveness.
NASA research finds that dormant viruses reactivate in over half of crew members on Space Shuttle and International Space Station missions. The reactivation rate increases with spaceflight duration, raising concerns for the success of deep-space missions. Effective prevention and treatment are crucial to safeguarding astronauts.
A recent study by the University of Pennsylvania School of Nursing found that the nursing work environment plays a significant role in how nurses evaluate EHR usability and its impact on quality and safety of care. The study, which analyzed data from over 12,000 nurses, showed that hospitals with better work environments had fewer repo...
A large study of nearly 30,000 adults found that consuming 300 mg of dietary cholesterol per day increases the risk of cardiovascular disease by 17% and death by 18%. The study also linked eating three to four eggs per week to a 6% higher risk of cardiovascular disease and an 8% higher risk of any cause of death.
A pilot study reveals that over a third of middle school kids had abnormal blood sugar or cholesterol levels. Two students were found to have diabetes, highlighting the need for routine screening in this age group.
The discovery of subtypes of atrial fibrillation enables individualized treatment, improving patient care. Novel results shed light on mechanisms and define clinical types based on the main cause.
New research reveals catheter ablation is effective in reducing atrial fibrillation recurrence and improving quality of life for patients, while drug therapy offers no significant benefit. However, the study found that catheter ablation did not reduce death or stroke risk compared to drug therapy.
A study by the USDA Forest Service reveals that more nitrogen from rain and snow reaches streams than previously believed, flowing downstream at a faster rate through US and Canadian forests. This unprocessed nitrate bypasses biological filters, contributing to forest decline and growth of nuisance vegetation.
Researchers found that men with high neuroticism are more likely to experience adverse events after prostate cancer surgery, such as erectile dysfunction and incontinence. The study suggests that personality tests may be a valuable tool for identifying at-risk patients and improving care.
A new interface system using augmented reality technology enables individuals with severe motor impairments to control a humanoid robot, allowing them to perform routine personal care tasks and interact with their environment. The system has shown promising results in improving the quality of life for users.
A new study by University of Central Florida researcher Ramon Hinojosa reveals that veterans are more prone to cardiovascular morbidity and conditions earlier than non-veterans, possibly due to modern warfare, diet changes and increased rates of obesity and mental illness.
Researchers developed a biosensor enhanced with gold nanoparticles for express diagnostics of stress and toxicological pollution. The sensor can detect heavy metals and monitor biomarkers like heat shock proteins 90 to indicate stress and cancer. This breakthrough improves bioluminescent analysis sensitivity.
A large observational study of over 29,000 people found no significant association between dietary cholesterol and the risk of cardiovascular disease or death. Conversely, egg consumption was linked to a higher risk of CVD, suggesting that other factors may contribute to this association.
A new study suggests that short-term strength training can improve liver health and blood sugar regulation in obese mice. The findings indicate that strength training may be a fast and effective strategy for reducing the risk of diabetes and fatty liver disease in obesity. However, further research is needed to confirm these results.
A team of researchers, led by Sungyoung Kim, is developing a comprehensive method to preserve and reconstruct the 'sound signature' of cultural heritage sites. The project focuses on auralization, which simulates unique acoustical environments in virtual or physical spaces, and aims to provide non-expert humanities researchers with dig...
Researchers found that night shift workers reported a higher rate of overactive bladder and poorer quality of life compared to day shift workers. The study highlights the importance of addressing increased urinary frequency in nightshift workers, particularly those under 50 years old.
A study of over 800 medical residents found that standardized training is needed to address the unique clinical needs of LGBTQ patients, who face significant health issues due to discrimination and harassment. Despite improvements in knowledge after online training, resident training years had no impact on baseline scores.
A new study found that 40% of large-scale randomised controlled trials in the UK and US failed to produce any evidence on whether an educational intervention boosts academic attainment. The researchers evaluated 141 trials involving over one million students, which tested various schemes.
Researchers at MIT have developed a new way to measure atomic-scale magnetic fields, not only up and down but also sideways. The technique uses nitrogen-vacancy defects in diamond to detect tiny variations in magnetic fields, providing high precision in multiple dimensions.
Scientists inserted a green-light receptor gene into the eyes of blind mice and, a month later, they regained sight. The researchers aim to develop this therapy for humans within three years, potentially restoring their ability to read or watch video.
A new diagnostic tool has been developed to detect ovarian cancer earlier, with high sensitivity and specificity rates. The test uses liquid biopsy proteomics to identify unique protein signatures in uterine fluid, promising improved detection rates for young women at high risk of developing the disease.
Researchers at the University of Cincinnati have created a continuous-monitoring device that tests sweat as effectively as blood, providing data over time to track health trends. This breakthrough technology holds promise for noninvasive testing and personalized care, paving the way for more accurate diagnosis and treatment.
A new study found that light physical activity can significantly lower the risk of cardiovascular disease among women 63 and older. The study, which involved over 5,800 women, showed a 42% reduction in heart attack or coronary death rates.
A University of East Anglia study found that individuals with a promotion focus tend to engage more in nutrition and exhibit greater knowledge of nutrition. This effect is stronger among high-income consumers, particularly men, suggesting targeted interventions can promote healthier habits.
Researchers at North Carolina State University have developed a microfluidic system that can synthesize perovskite quantum dots across the entire spectrum of visible light. The system drastically reduces manufacturing costs and allows for real-time process monitoring to ensure quality control, enabling mass production of high-quality QDs.
A study analyzing 646 Catholic hospital websites found that many do not disclose their religious identity and health care practices. Some patients may avoid these hospitals due to concerns over restrictive policies on reproductive and end-of-life care, according to the research letter.
A team at Politecnico di Milano has developed an electronic circuit that can solve systems of linear equations in a single operation, accelerating computing by orders of magnitude. The memristor-based circuit boasts superior performance to classical digital computers and even quantum computers, paving the way for AI breakthroughs.
Research has led to increased understanding of genetic changes in cancer, highlighting the potential for personalized care in children with cancer. Genetic profiling can inform prognosis and treatment decisions, providing critical information about tumor progression and response.
Researchers at Brookhaven National Laboratory have identified the causes of capacity fading in nickel-rich layered materials, which could lead to improved battery performance for electric vehicles. The team used multiple research techniques, including synchrotron light sources and machine learning, to pinpoint the problem and provide p...
Researchers used machine learning techniques on MRI brain scans to predict cognitive development in children aged 2. The study found that white matter connections at birth are highly predictive of future cognitive outcomes.
A study of a single male narwhal found that it spends over half its time diving to depths of over 700m in search of halibut, cod, and squid. The whale can also last for several days without eating, using stored energy reserves.
A recent study by Vetmeduni Vienna reveals that wolves and dogs cooperate intensively with humans but differ in their approach. Wolves show more initiative, leading the interaction, while dogs follow human behaviour. The study proposes that dogs' submissive tendencies are a result of domestication, which helped minimize conflicts.
A new paper reviews key theories and methods to study puberty, highlighting its importance in understanding adolescent development and welfare. The review emphasizes the need to integrate sociological and psychological impacts into research models, as current approaches focus solely on biological processes.
A study by the University of Bristol found that non-suicidal self-harm, cannabis use, and exposure to self-harm in friends or family were key predictors of future suicide attempts. The study followed 310 adolescents with suicidal thoughts over five years and found that one in five attempted suicide.
A study of over 1000 adolescents found that bullying roles persist into adulthood, with victims often transitioning out but perpetrators remaining involved. The research sheds light on the evolution of bullying and its long-term consequences.
Researchers have made a breakthrough in understanding antibody-mediated rejection, a major challenge in organ transplantation. They discovered the critical amino acids and binding site of alloantibodies on HLA molecules, providing new avenues for developing therapies to prevent or treat this type of rejection.
Researchers from German Cancer Research Center have successfully reconstructed biomolecules in their mirror-image form. This breakthrough could lead to the creation of mirror-image therapeutic proteins that are protected from biological breakdown and do not provoke immune responses.
Researchers have developed 3D organ-on-a-chip models to test the effects of different levels and types of radiation on human tissues. This technology could lead to more effective therapies with fewer side effects for cancer patients.