Scientists have discovered that bacterial proteins and endotoxin activate the inflammasome, leading to pyroptosis and the release of tissue factor, which initiates blood clotting. This understanding may lead to new treatments for sepsis by targeting inflammatory responses.
Rainer Hedrich's new project aims to investigate the molecular mechanisms underlying frequency-dependent decision making in Dionaea, using mutants with disturbed stimuli transmission. The researcher hopes to determine the cellular basis for counting and decision-making in plants.
Researchers have found that the structure, concentration and interactions of tannins in wine influence dryness perception. Trained sensory panelists perceived Cabernet Sauvignon as dryer due to its higher tannin content, while added tannins didn't change dryness perception in Pinot Noir.
Researchers analyzed 13 honeys from the Czech Republic to identify proteins, revealing a similar ratio of known and previously unreported proteins. The study also shed light on allergens present in honey, which could aid in treating allergies.
A new study published in Nature assesses the location and extent of the planet's remaining free-flowing rivers, finding that only 37% of the world's 246 longest rivers are still unimpeded. The researchers' global assessment highlights severe degradation and offers a method for tracking the status of free-flowing rivers over time.
Researchers from NYU introduce a voltage-controlled topological spin switch (vTOPSS) that reduces heat generated and energy used in computing. The new method enables faster and more secure computing by replacing traditional silicon transistors, increasing functionality and circuit design possibilities.
Researchers at Johns Hopkins Medicine have found that a broccoli sprout compound can restore the brain's glutamate balance, which is linked to schizophrenia. The study suggests that supplementing with sulforaphane, a compound found in broccoli sprouts, may reduce the need for traditional antipsychotic medications.
The collaboration aims to increase metal component production by up to 100 pounds per hour, reducing costs and lead times for US manufacturers. By leveraging data analytics and advanced technologies, ORNL and Lincoln Electric aim to showcase American manufacturing capabilities in the global market.
A new study from Illinois Institute of Technology found that meals including fresh avocado significantly suppressed hunger and increased meal satisfaction in overweight and obese adults. The research also showed that avocados limit insulin and blood glucose excursions, reducing the risk of diabetes and cardiovascular disease.
The Estée Lauder Companies' research focuses on defending skin from environmental stressors and aging, demonstrating the antioxidant benefit of eucalyptus extract. The team discovered that activating sirtuins with key ingredients increases skin fibroblast activity to combat aging.
Research by Dartmouth College and Princeton University researchers finds that creative experts are better at imagining distant experiences due to a unique neural system. They use the dorsal medial system default network, associated with empathy, to think about other people and perspectives.
Athletes consider concussion symptoms' impact on their health, team prospects, and performance culture, influencing their reporting decisions. The study highlights the importance of athlete education and organizational culture in encouraging concussion reporting.
A global study predicts a 53% rise in chemotherapy demand by 2040, with an estimated 15 million patients needing treatment annually. The study recommends expanding the chemotherapy workforce to 100,000 physicians by 2040 to deliver optimal treatment.
Experiments using Hellman's Real Mayonnaise and accelerated conditions confirm the instability of elastic-plastic material is a function of initial conditions. The study provides new insights into the dynamics of materials in extreme environments, relevant to inertial confinement fusion.
Scientists have successfully assembled protein cages that can be readily disassembled yet withstand extreme conditions. The breakthrough uses gold to overcome geometrical and complexity challenges in creating these nanoscale structures.
A new study found that approximately half of former professional athletes with multiple concussions had higher than normal levels of tau protein in their cerebrospinal fluid, linked to chronic traumatic encephalopathy (CTE). The athletes with high tau levels scored lower on cognitive tests and brain scans showed white matter damage.
A study by the Alliance of Bioversity International and the International Center for Tropical Agriculture reveals that Vietnam can achieve significant reductions in greenhouse gas emissions through affordable agricultural practices, increasing productivity, and reducing inputs. Implementing these measures could eliminate up to 51% of p...
Research from the University of South Australia reveals that circus skills programs deliver significant mental health benefits for Australian children, with a 7:1 return on investment. Children participating in these programs showed improvements in stress relief, self-esteem, confidence, and socialization.
University of Kansas researchers have secured a $1.7 million grant to develop an eating disorder screening tool for the military and Veterans Affairs. The project aims to identify organizational barriers to detecting and treating eating disorders, which can have a high mortality rate among mental health disorders.
The article explores quality improvement in cardiovascular imaging, highlighting the importance of consistency in result reporting, patient safety, and efficient care delivery. Successful projects and strategies for teaching QI to medical trainees are also discussed.
The Excellence in Prehospital Injury Care Project has doubled the survival rate of severe traumatic brain injury victims and tripled the survival rate among those who were intubated. First responders are now taught to treat and prevent the
A new study published in Proceedings of the National Academy of Sciences found that people's beliefs about the source of information significantly impact how they process it. Establishing credibility for news sources is crucial to combatting fake news and mitigating its effects on democratic institutions.
The article discusses the practical clinical applications of cardiac computed tomography-derived fractional flow reserve (FFR-CT) in evaluating coronary artery disease (CAD). FFR-CT analysis may help reduce additive functional testing for patients with intermediate stenosis, providing a more efficient and accurate assessment of CAD.
A new framework, secure base provision, predicts infant attachment with greater accuracy than traditional sensitivity-based approaches. Caregivers need only respond correctly 50% of the time to have a positive impact on their baby's development.
A global study of 487 wheat genotypes has mapped the ancestry and genetic diversity of bread wheat, revealing a rich pool of genetic variation that can be used to improve crop resilience. The findings highlight the need for continuous breeding efforts to adapt wheat to changing climates.
Urban trees exhibit accelerated growth but higher mortality rates than rural counterparts, resulting in a net loss of street-tree carbon storage over time. Strategic planting and maintenance initiatives can help maximize urban greening efforts as a climate-mitigation tool.
Researchers at DGIST created a single-layer graphene-based device that can generate and store power, with maximum transparency of 77.4%. The device also features touch-sensing systems and can be self-charged and stored.
A new study published in Neuropsychopharmacology suggests that early life adversity can lead to negative thinking patterns and impairments in reward-related cognition. This can increase the risk of developing depression, particularly as it affects how individuals process emotional information.
A new study by Gregory Erhardt and colleagues found that popular ride-sharing companies like Uber and Lyft increased traffic congestion in San Francisco by 62% between 2010-2016. The analysis also revealed that average speeds decreased by 13%, leading to less reliable travel times.
The American Cancer Society aims to lower overall cancer mortality 40% between 2015 and 2035, primarily through reducing risk factors like smoking and excess body weight. The goal is based on applying favorable cancer mortality trends among college graduates to the entire population.
A new species of Jurassic scansoriopterygid dinosaur with associated feathers and membranous tissues has been discovered, providing new insights into the origin of flight in Dinosauria. The well-preserved skeleton of Ambopteryx longibrachium preserves a unique wing structure supported by a rod-like wrist bone.
A European research project called Just4All is analyzing barriers to access to justice for people with disabilities and providing training to legal professionals. The project also includes an online course, database, and analysis of regulations and case law.
Researchers have developed a new filter to better map the dark universe, cutting through galaxies' messy emissions to provide clearer windows into dark matter and dark energy. The new method uses shearing effects to reduce errors and provides more accurate measurements.
A PSU researcher is working to identify the behavioral health needs of NICU parents and develop a sustainable program to support them. Studies show that parents with babies in the NICU are at higher risk of depression, anxiety, PTSD, and substance abuse.
Researchers found that rural-specific resources are not widely used in introducing innovation, but migrants who use pre-existing contacts and build on previous life experiences are most innovative. Policies should support diversification and acknowledge differences within rural communities.
A new pilot program aims to increase diversity and inclusion in STEM fields by leveraging a successful program model. The program showed promising results, with underrepresented students experiencing higher retention rates and GPAs compared to non-participants.
Researchers developed deformation microscopy to non-invasively probe cell mechanics and understand how physical changes contribute to cell development and disease. The technology reveals intricate structural architectures and dynamic cell deformation, opening new avenues for studying mechanobiology.
Researchers at University of Cologne and Bonn developed a method to visualize fine surface structures using gold-coated samples in computer tomography. This technique allows for detailed analysis of organisms with previously invisible features, with applications in biology, taxonomy, and education.
Researchers used MRI scans to examine the brains of 1,327 individuals with ASD and typically developing individuals, finding that cortical anatomy varies significantly between groups. The study also found that brain differences are more pronounced in girls with ASD, particularly those with lower cognitive ability.
A study characterizes the phenotypic spectrum of individuals with aggrecan gene (ACAN) mutations, revealing common symptoms such as short stature and accelerated bone age. Researchers investigate the efficacy of growth hormone therapy in improving height SDS scores in children with ACAN deficiencies.
Researchers at Uppsala University found that inhibiting ribosome biogenesis can revert aggressive tumors to a non-invasive state, potentially regaining sensitivity to hormonal therapy. The study also showed a marked reduction in lung metastases.
A recent study has found that rural areas are experiencing a faster rate of obesity growth than cities, with an average increase of 2.1 kg/m2 in women and men since 1985. This trend is driven by factors such as increased income, better infrastructure, and changes in food consumption patterns.
Researchers have identified two fast-acting compounds that kill parasite-supporting bacteria after a single dose in mouse models of filarial diseases, potentially eradicating the condition. The standard-of-care treatment is limited by its duration and availability to pregnant women and children.
A new study finds radioactive carbon from nuclear bomb tests has reached the deepest parts of the ocean, contaminating crustaceans' muscle tissues and affecting their longevity. The study suggests human pollution can quickly enter the food web and make its way to the deep ocean.
Eight researchers from the University of Texas M. D. Anderson Cancer Center have been awarded $100,000 fellowships to conduct high-impact cancer research over two years. The Andrew Sabin Family Fellowship Program aims to encourage creativity and innovation in cancer research.
Undergraduate students from DGIST won an international journal publication on their research about MAOA genetic variations and aggression. The study found that individuals with '4.5R alleles' showed a stronger reaction to aggressive-inducing stimuli, suggesting a possible bioscientific interpretation for aggression.
A team of microbiologists and pulmonologists at the University of Pennsylvania have identified a previously unknown viral family, Redondoviridae, which is the second-most common DNA virus in human lung and mouth specimens. The virus is associated with severe critical illness and gum disease, respectively.
Researchers at King's College London have made a groundbreaking discovery that genetic therapy can heal heart damage caused by a heart attack. The study used microRNA-199 to stimulate cardiac regeneration in pigs, resulting in almost complete recovery of cardiac function.
A new analytical tool for ultra-trace ratiometric detection of capsaicinoids has been developed, enabling the quick and reliable quantification of spicy tastes in kimchi. The method uses a combined technology of endogenous fluorescence imaging techniques and total internal reflection fluorescence microscopy.
Researchers at the University of Bath have successfully waterproofed perovskite solar cells using a graphite coating, enabling the direct generation of clean hydrogen fuels from sunlight. This breakthrough could lead to more affordable and sustainable solar energy solutions.
Researchers have found that smokers with COPD have significant unmet mental health care needs, particularly anxiety and depressive symptoms. These symptoms can impact many COPD-related outcomes, including hospital readmissions and exacerbations.
A new study confirms grapefruit juice prolongs the QT interval, posing a risk to patients with congenital long QT syndrome and those taking QT-prolonging medications. The findings call for stronger warnings to protect these patient groups.
A new UTSA study has redefined the role of a cell's cytoskeleton, finding it plays a crucial part in energy transfer and information processing within neurons. This breakthrough challenges traditional views of the cytoskeleton's primary function in supporting cellular structure.
Researchers from Hokkaido University used underwater pressure sensors to measure the volume of icebergs breaking off from a glacier, finding a positive correlation with wave amplitude. The study also revealed that submarine melting caused most of the mass loss at the glacier front.
New research shows that community forest management in Nepal has simultaneously reduced deforestation and poverty. The study found a 37% relative reduction in deforestation and a 4.3% relative reduction in poverty, benefiting over 1.36 million households.
Researchers have identified genes responsible for eucalyptus oil production, enabling the potential use of eucalyptus as a renewable fuel source. This breakthrough could enable faster and more efficient domestication of eucalyptus trees for biofuel production.
Advancements in zero-emission fuel cells could make them economically practical for vehicle power, with improved durability and cost-effectiveness. The new technology has the potential to replace traditional gasoline engines and pave the way for a cleaner transportation system.
A new study suggests that mitochondrial function may explain the link between general intelligence, health, and aging. Chronic stress can damage mitochondria, leading to age-related diseases such as Alzheimer's, highlighting the importance of promoting healthy mitochondria through regular exercise and a balanced diet.
A new survey of over 200 internal medicine residents suggests that better training is needed to increase the prescribing of PrEP, a proven tool to prevent HIV transmission among high-risk individuals. The study's findings highlight the importance of improving residency training programs nationwide.
The study found that Moringa leaves contain 30 times more iron and 100 times more calcium than spinach, making them a rich source of essential nutrients. The tree's roots and stem parts also exhibit anti-inflammatory and antioxidant properties, highlighting its potential as a superfood.