Researchers have developed a new method to visualize protein complexes in their natural environment, revealing the structure of the Arp2/3 complex and its role in cell motility. The study provides insights into the regulation and activity of this important protein complex, which could lead to better understanding of disease mechanisms.
A recent study suggests that pregnant women infected with SARS-CoV-2 during the third trimester are unlikely to pass the virus to their newborns. The study found low levels of protective antibodies in umbilical cord blood, indicating limited transfer of maternal antibodies through the placenta.
Researchers at the NIH have isolated promising nanobodies against SARS-CoV-2 that may prevent infections and detect virus particles. The nanobodies were produced by a llama named Cormac and showed high affinity for blocking the spike protein's interaction with human cells.
Researchers found that surgery in addition to treatments like chemotherapy and radiation therapy increased the length of survival for stage four breast cancer patients. The study, published in Annals of Surgical Oncology, suggests that knowing a cancer's biological subtype can help determine effective treatment plans.
Researchers have created a new composite hydrogel with tantalum particles that can effectively seal off damaged blood vessels, providing rapid and stable bleeding control. The gel exhibits shear-thinning capabilities, allowing for easy deployment using standard catheters.
The European Centre for Disease Prevention and Control (ECDC) has released four COVID-19 vaccination strategies for EU/EEA countries, developed using mathematical modeling to inform prioritization. The strategies prioritize groups at high risk of severe disease and death, highlighting the importance of vaccination of healthcare workers.
A joint Anglo-German research project will analyze the practice of translation in cultural magazines from 1945-1965. The project aims to understand how these magazines used translated texts to forge new European identities, and explore the significance of translation in reconfiguring a vision of Europe after WWII.
A study published in Thorax found that higher intake of advanced glycation end-products (AGEs) from non-seafood meats is associated with increased wheezing in children. Researchers examined data from the National Health and Nutrition Examination Survey and found a significant link between AGE intake and respiratory symptoms.
Researchers at Trinity College Dublin identify genetic mutations linked to ultra-rare condition ALSP, revealing that dysfunctional white blood cells drive brain damage and BBB breakdown. The study's findings may pave the way for targeted therapies for other forms of dementia.
A research team from the University of Helsinki has discovered a tree hyrax in Kenya's Taita Hills that may belong to an unknown species. The 'strangled thwack' calls of the animal have not been described anywhere else, suggesting a possible link to different species.
A modeling study found daily symptom screening with PCR testing in nonhospital care sites significantly reduces COVID-19 infections and lowers healthcare costs. The study associated this intervention with substantial decreases in infections across various epidemic scenarios.
Researchers have created a millimeter-band signal propagation model that can predict wireless signal behavior in industrial environments. The study demonstrates the potential of Wi-Fi technology to replace cabled connections in manufacturing processes, enabling faster and more reliable data transfer.
Researchers developed two new mammogram-based measures of risk, combining them to predict breast cancer risk more effectively than known genetic and breast density factors. The new measures could improve screening, reduce mortality, and make it less stressful for women.
Research at Hebrew University found fenofibrate effective in treating COVID-19 by reducing fat buildup in lung cells. Clinical trials are underway to confirm the findings and explore its potential as a treatment for severe COVID cases.
Scientists have developed a new metallic glass electrode made of thin palladium-based metallic glass films, which are 85% more efficient in oxidizing methanol than platinum-based analogs. The film is also resistant to corrosion and could replace existing materials in the energy sector.
A recent Canadian study revealed that women with Attention Deficit Hyperactivity Disorder (ADHD) are eight times more likely to have attempted suicide compared to their male counterparts. The study also found that adults with ADHD who experienced childhood parental violence had triple the odds of attempting suicide.
A national study found significant sex and age-based differences in nonfatal opioid overdoses among youth, with female youth between 11-16 having a higher incidence. The study highlights specific risk factors that could inform targeted interventions to prevent opioid overdoses in adolescents and young adults.
The article assesses progress in healthcare quality during the COVID-19 pandemic, focusing on system cohesion and organizational capabilities. It highlights key findings on how to improve healthcare systems and enhance patient care.
A majority of European anaesthesiologists and intensive care specialists believe that precious ICU capacity should be shared between nations during international emergencies. The study found that around 60% were in favour of a centralized European institution to distribute such resources.
A study at Columbia University Irving Medical Center found that specific functional units within genes, called exons, can impact autism severity. The researchers analyzed genetic and clinical data from over 2,500 people with autism and discovered that children with truncating mutations in the same exon often exhibit similar symptoms.
Researchers found that rural girls in South Africa rely on peer, parental, and environmental factors to prevent pregnancy and HIV/AIDS, rather than modern contraceptive methods. The study highlights the need for more comprehensive education on sexual health beyond HIV/AIDS prevention.
The US child welfare system has become bogged down in unnecessary investigations and child removals, disproportionately targeting poor African American families. Most reports of neglect are actually about manifestations of poverty, and removing children from their families undermines the ability to focus on providing services.
ETH Zurich researchers use a novel method called KARMA to analyze protein complex assembly, revealing a hierarchical principle and durable scaffold. The technique allows for the reconstruction of precise assembly sequences, opening up new avenues for studying biological processes.
A new drug combination combining a widely used diabetes treatment with an experimental cancer drug has shown significant improvements in blood glucose control and weight loss in mice. The combination treatment enhanced insulin secretion and reduced body weight, paving the way for clinical studies.
Research supports early start to musical training, but underlying reasons are more complex. Familial influences, such as genetic factors and encouraging family environment, play a significant role.
Researchers from the US, China, and Russia have discovered a novel hydrogen hydrate that forms at room temperature and low pressure. The new form of ice has three water molecules per hydrogen molecule, showing promise for cost-effective hydrogen storage solutions.
Cornell University is developing a system to convert cattle manure into methane and other products to meet peak heating demands. The proposed system produces approximately 909 million liters of renewable natural gas per year, providing 97% of the campus's annual peak heating demand.
A collaboration of three clinical trial platforms has paused enrollment for critically ill COVID-19 patients due to the lack of improvement in outcomes with full-dose anticoagulants. Moderately ill hospitalized COVID-19 patients can still be enrolled, and the trials will continue to analyze data.
A novel computational tool called CShaper speeds up the analyzing process from hundreds of hours to a few hours by computer. It can segment and analyze cell images systematically at the single-cell level, enabling biologists to decipher the contents of these images within a few hours.
Researchers found that present-day Mariana Islanders' ancestry is linked to the Philippines, suggesting an Island Southeast Asia origin for the first settlers. The study also suggests a close link between Guam skeletons and early Lapita individuals from Vanuatu and Tonga.
Scientists at Hokkaido University have achieved a record-setting thermoelectric figure of merit for metal oxides, which can be used to enhance thermoelectric power generation. The material exhibits a high ZT value and stability across a range of operating temperatures.
Researchers from NUS have invented a new method of anti-counterfeiting called DeepKey, using 2D-material tags and AI-enabled authentication software. The technology works faster, achieves highly accurate results, and uses durable identification tags that can withstand extreme temperatures and environmental conditions.
A new experiment provides insights into transient atomic states, enabling better understanding of photocatalysis, elementary steps in photosynthesis and radiation damage. The study uses high-resolution electron spectroscopy to capture a snapshot of the short-lived state produced when X-rays interact with neon atoms.
Researchers have created a new adhesive that can be cured using a magnetic field, offering a more efficient alternative to traditional methods. The 'magnetocuring' glue has the potential to revolutionize industries such as sports equipment, automotive and electronics manufacturing.
Functional hydrogel coatings have various functions, including sensing, actuation, drug delivery, and conductivity for neural electrodes. Research directions include optimizing coating methods for mass production, long-term stability, and testing adhesion.
The ACTIV-3 trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), tested LY-CoV555 against placebo in hospitalized COVID-19 patients. The trial found that LY-CoV555 did not provide clinical benefit compared to placebo.
Military personnel who receive lethal means counseling and a cable lock are more likely to use a gun safe and unload firearms before storing, according to a Rutgers study. The combination of these interventions resulted in greater adoption of safe storage methods, reducing the risk of military suicide.
A new study led by US and Indian researchers found that air pollution in India resulted in 1.67 million deaths in 2019, accounting for 17.8 percent of all deaths in the country. The economic loss was $36.8 billion, equivalent to 1.36 percent of GDP.
Researchers found that surgery in addition to treatments like chemotherapy and radiation therapy increased survival for stage four breast cancer patients. Patients with hormone receptor-positive tumors saw a prolonged length of survival when their treatment plan included surgery.
A survey of adults with kidney failure reveals that most own mobile devices and have intermediate or advanced mobile health proficiency. The main reasons for using mobile health include making appointments, communicating with healthcare personnel, and obtaining laboratory results.
A new liquid bandage sensor measures the amount of oxygen reaching transplanted tissue, a crucial measure of its viability, and detected tissue oxygenation as well as the gold standard of an oximeter. The technology eliminates restrictions on patient movements and provides a major advancement over existing methods.
A new study found that COVID-19 mortality rates in hospitals are linked to the number of cases in the surrounding community. Hospitals with high case rates had worse outcomes, while those with declining case rates saw significant improvement over time.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism uses machine learning to predict gestational diabetes in Chinese women. The researchers analyzed nearly 17,000 electronic health records and found that low body mass was associated with an increased risk of gestational diabetes.
A new bio-inspired medical endoscope has been developed to acquire 3D visible light and near-infrared fluorescence images simultaneously, aiding surgeons in pinpointing cancerous tissue. The instrument combines high-resolution 3D imaging with the mantis shrimp's capability to detect multiple wavelengths of light.
Researchers at Rice University developed an optogenetic control system to turn on and off genes in gut bacteria, extending the lifespan of transparent worms by up to 50% by regulating mitochondrial function. The study suggests that gut bacteria directly impact health and disease, and that controlling metabolite production with precisio...
A study by the University of Konstanz found that voluntary motivation to comply with anti-COVID-19 policies is relatively high in Germany, but can be crowded out by enforcement. Measures like limiting contacts and vaccinations showed higher agreement when implemented voluntarily, while wearing masks and travel restrictions had the same...
Chronic pain and emotional pain are intertwined, with opioids making things worse in the long term. Researchers recommend tapering down or switching to buprenorphine for high-dose long-term opioid users without improvement in pain and function.
A newly discovered receptor in Arabidopsis thaliana has helped scientists understand the evolution of the GET pathway, a mechanism that enables membrane protein transport. The receptor's discovery provides crucial insights into the evolution of this pathway across organisms.
Researchers at the University of Ottawa have identified the molecular defects associated with LIC Syndrome, a rare genetic disorder that causes mortality in young children. The study found that small mutations in the NSMCE3 gene affect the Smc5/6 complex's ability to compact DNA, leading to severe defects in DNA repair.
Scientists at Durham University have discovered a new type of brain cell called Vector Trace cells, which can store maps of places we've been and track the distance between objects. This discovery could lead to earlier diagnosis and treatment of Alzheimer's disease.
New research from Northwestern University has found that including all three flavors of neutrinos in a study provides deeper knowledge of dying stars and unravels existing hypotheses. The study reveals that ignoring any flavor can lead to incomplete results, emphasizing the importance of complexity in models.
A study by Brigham and Women's Hospital researchers found that combining mandatory mask-wearing and social distancing policies can prevent 87% of infections among students and faculty. Routine testing is also effective in preventing infections but at a higher cost.
Researchers at HPSTAR have discovered a universal relationship between regulating off-centering distortion and maximizing photoluminescence in halide perovskites. By applying high pressure, they achieved optimal PL performance, ten-fold enhancement, and new paths to high-performance optoelectronic materials.
Researchers used genomics and epidemiology to study how African Salmonella evolved to cause bloodstream infections, killing ~50,000 annually. A new antibiotic-susceptible lineage emerged in Malawi in 2016, linked to changes in antibiotic usage between 2002-2015.
COVID-19 causes lung destruction through the SARS-CoV-2 virus, leading to hypoxemia and inflammation. Pneumolysis can result in irreversible fibrosis and death if not treated with oxygen therapy and anti-inflammatory medication.
Researchers found that deep, slow-slip behaviors beneath subduction zones, such as Cascadia, may control the timing and behavior of megathrust earthquakes. Slow-slip events, which occur at a deeper depth than damaging earthquakes, release energy in different directions, primarily down.
A new study from Oregon State University uses fecal samples from Eastern North Pacific gray whales to assess endocrine levels and establish hormone baselines for stress and reproduction. The findings provide valuable context for understanding how human activities impact whales.
A remarkably preserved 57,000-year-old wolf pup named Zhùr has been uncovered in the Yukon, offering a unique window into the lives of ancient wolves. The mummy's genome analysis revealed that she was descended from wolves from Russia and Siberia, and her diet consisted mainly of aquatic resources like salmon.
A recent study by the University of Colorado Anschutz Medical Campus found that employees in small businesses with strong health and safety climates reported better well-being during the COVID-19 pandemic. The research team distributed a COVID-specific survey to 491 employees from 30 small businesses across Colorado, revealing a positi...
Dr. Tonya Vitova and Professor Laurent Schmalen are awarded ERC Consolidator Grants to study actinide bonds and develop energy-efficient communication technology. Their projects aim to improve the environmental behavior of actinides and reduce complexity and energy consumption in communication systems.