Rutgers scientists expand Darwin's theory of evolution to consider DNA stability as an energy code, enabling analysis of the human genome and explaining long-term survival of species characteristics. The study's findings provide new ways to analyze genomes and potentially improve selection of DNA targets for therapeutics.
The global built environment sector must drastically reduce its climate impact to meet UN sustainability goals. A roadmap presented at the Beyond 2020 World Conference calls for powerful efforts and swift action from institutions, businesses, and urban planners.
Since its 2011 approval, TAVR has become the leading choice for aortic valve replacement in the US, with increasing volumes and improved outcomes. The STS/ACC TVT Registry data show significant reductions in mortality, stroke rates, and length of stay, while pacemaker implantation rates remain stable.
A new optical imaging technology called PANORAMA has been developed to detect and study nanoscale objects as small as 25 nanometers in diameter. This technology uses unscattered light to monitor changes in transmission and determine the target's characteristics, making it possible to view nanoparticles directly without labeling.
A team of scientists has identified a region of the thalamus as a key source of top-down information, which is essential for processing sensory signals in the context of past experiences. This discovery sheds light on how the brain encodes and retrieves memories, particularly in cases of brain disorders such as autism and schizophrenia.
A new study published in the American Journal of Clinical Nutrition found that consuming dairy foods did not directly affect blood sugar levels in people with metabolic syndrome. However, participants on a full-fat dairy diet gained weight and those on low-fat or full-fat diets experienced reduced insulin sensitivity.
A study analyzing snailfish and amphipods from deep-sea trenches found high mercury concentrations, suggesting human activity contributes to ocean pollution. Mercury accumulates in fish consumed by humans, posing a health risk.
Researchers have developed a novel neuroregenerative gene therapy that converts glial cells back into functional neurons, reversing glial scar tissue. This treatment also promotes brain recovery in mouse models of ischemic stroke and Huntington's disease, offering a promising solution to the glial scar problem.
The Sustainable Innovation Fund will provide £191 million in support for industrial research projects focused on decarbonizing buildings. Cranfield University is committed to delivering Net Zero and sees this project as an opportunity to develop renewable cooling and heating systems.
A Portland State University study found that pharmacy dropboxes increase customer awareness of proper drug disposal and reduce improper disposal methods. The study suggests that legislation mandating dropboxes at pharmacies and industry funding for disposal are crucial to addressing this issue.
A study analyzed 18 songbird species and found that postfledging bottlenecks increased the survival rate of at least one offspring, suggesting parental manipulation can harm fledglings. The findings imply that parent-offspring conflict may impact other animals' life transitions.
Researchers reconstructed 3,000 years of storm history in the southern Marshall Islands to find that tropical cyclones were more frequent during the Little Ice Age. Climate change is expected to shift this region's cyclone formation northward, but also decrease its frequency.
A new paper argues that robots designed for older adults can provide essential human values like social interaction, emotional fulfillment, and bodily integrity. The author suggests that Western cultures' narrow view of sex as lust needs to be challenged, and that robots can enable people to experience physical affection and self-respect.
The EA2176 study aims to enroll 205 patients in the US with inoperable advanced squamous cell anal cancer, comparing standard chemotherapy with or without nivolumab. The trial seeks to determine if adding immunotherapy will prolong progression-free survival and reduce symptoms.
Researchers at Virginia Tech prove that the mixture of sodium, chloride, potassium, calcium, urea, and bicarbonates in sweat can clog sweat ducts naturally, replacing metallic salts. A lab experiment demonstrates this concept using artificial sweat and a microchannel, showing a gel-like plug forms to seal the duct.
A recent study on US social mobility found that regions have shifted unevenly over the last century, with some areas scoring high in social mobility while others score low. The study, led by Arizona State University's Dylan Connor, tracked 2 million children from childhood to adulthood and found that urban Midwest areas have struggled ...
Researchers at MUSC discover lysyl oxidase plays key roles in promoting fibrosis in scleroderma, and its levels can be used to monitor treatment response. The findings suggest LOX could be a promising biomarker for assessing fibrosis progression or regression.
Designing and marketing sexbots for older adults with disabilities could promote emotional health and wellbeing, counter ageism and stereotyping. This is based on research showing that sexual desires are fundamental to human dignity and respect, even in older age.
Scientists have confirmed that magnetars, extreme stars with strong magnetic fields, generate fast radio bursts (FRBs). The discoveries were made using four European radio telescopes and provide new insights into the origins of FRBs. The research aims to pin down how these extreme stars create brief blasts of radiation.
Fiber optic sensors have been upgraded with an advanced encoding and decoding system, allowing for faster and more accurate data transmission over wider areas. This technology, developed by EPFL engineers, enables real-time monitoring of hazards such as pipeline cracks and civil engineering deformations.
A study published in PLOS One suggests that a freely available test, known as the UNSW Face Test, is able to rank facial recognition abilities with precision. Researchers argue that this test is perfect for identifying exceptional face recognisers and could lead to breakthroughs in fields such as law enforcement and national security.
A national survey of over 1,000 young US adults finds alarming levels of loneliness associated with significant mental health issues, including depression, anxiety, substance use, and addiction. The study emphasizes the importance of providing access to psychological help and promoting social connectedness to address these problems.
Researchers developed statistical methods to track and forecast wildlife populations across borders, revealing detailed dynamics of entire populations across large spatial scales. The study's findings provide new insights into wildlife management and conservation efforts for species like brown bears, grey wolves, and wolverines.
Research found that people in developing countries consume less bushmeat over time as they migrate to cities, possibly due to increased access to alternative protein sources and changing social norms. Children in urban areas tend to have lower appetites for wild game than their parents.
Dr. Lisa R. Young is recognized for her research and leadership in pediatric pulmonary medicine and rare lung diseases. Her work has led to a greater understanding of these diseases and will drive novel diagnostic and treatment strategies.
A novel engineered C. glutamicum strain can produce high-level glutaric acid from glucose, breaking the record for the highest titer ever reported. The new strategy employs systems metabolic engineering strategies, including introducing Pseudomonas putida genes and optimizing culture conditions.
Researchers argue that introducing carbon pricing now would result in marginally less disruption and help drive greener economic activity. The tax could prompt industries to move away from fossil-fuel intensive practices towards long-term sustainability.
A global clinical trial led by Cleveland Clinic found that rilonacept resolved acute pericarditis episodes and reduced recurrence risk. The study showed 81% of patients on rilonacept reported no symptoms, compared to 25% on placebo.
A Baylor University study finds that cynical hostility may prevent a healthy response to stress over time, leading to increased cardiovascular strain. This type of hostility is characterized by negative beliefs and attitudes towards others' motives and trustworthiness.
A new study by UC San Francisco researchers found that California's Black and Hispanic communities received less benefit from regionalized heart attack care protocols. Despite improved access to PCI-capable hospitals, survival rates remained unchanged for minority groups, whereas whites in non-minority communities showed better outcomes.
A new diagnostic tool has been developed to predict which cancer patients are most likely to benefit from immunotherapy treatments. The tool analyzes the interactions between immune cells and tumor cells, as well as the activation state of immune checkpoints.
A new outpatient procedure has been shown to provide significant pain relief for patients with moderate to severe osteoarthritis in their hip and shoulder joints. Treatment involves the placement of needles where sensory nerves exist, followed by a low-grade current that 'stuns' them, slowing pain transmission to the brain.
Researchers found that severe reactive astrocytes cause irreversible neurodegeneration and cognitive deficits in just 30 days. Mild reactive astrocytes can reverse their reactivity, but excessive oxidative stress transforms them into neurotoxic severe reactive astrocytes.
Researchers discovered that the Chapare virus can spread from person to person in healthcare settings, posing risks of additional outbreaks. The virus was found to be transmitted through bodily fluids and may have been circulating in Bolivia for several years.
A new study found that in-kind payments successfully encouraged farmers to cultivate and conserve rare crops and varieties. The innovative payment scheme, known as Payment for Agrobiodiversity Conservation Services (PACS), has been well-received by farmers and policymakers in four Latin American countries.
Theoretical researchers at the University of Chicago have found a way to make quantum sensors exponentially more sensitive by harnessing a unique physics phenomenon. This breakthrough could lead to improved detection and diagnosis of diseases, prediction of natural disasters, and exploration without digging.
Researchers at the Buck Institute have identified chronic inflammation as a driver of NAD+ decline, a key metabolite central to an efficient and healthy metabolism. Senescent cells activate CD38, which degrades NAD+, leading to age-related diseases. Blocking CD38 activity may offer a new target for therapeutic interventions.
A University of Kansas researcher found that media coverage incorporating emotion can influence how people think about climate change, making it a more significant issue. Non-governmental organizations (NGOs) also play a crucial role in creating resonance with audiences through their social media activism.
Researchers at UC Santa Barbara have developed a new approach to boost NMR signal detection in previously 'invisible' regions. By using dynamic nuclear polarization with transition metal vanadium, they have created hyperfine DNP spectroscopy, which offers a broader frequency range and can analyze local chemistry around transition metals.
Researchers found patients with a particular type of human leukocyte antigen (HLA) B44 were more likely to benefit from immunotherapy in melanoma but not non-small cell lung cancer. The study identified mutations driving the different responses, paving the way for better patient stratification and potential therapy design.
Researchers discovered that short bursts of exercise induce changes in the body's levels of metabolites correlated to improved cardiometabolic, cardiovascular, and long-term health. Favorable shifts in specific metabolites were found to be associated with reduced risk of heart disease, diabetes, and decreased longevity.
A randomized controlled trial comparing laparoscopic and open liver surgery for patients with resectable colorectal liver metastases found no significant difference in 5-year survival outcomes. The study suggests that the laparoscopic approach may provide better short-term outcomes but does not jeopardize oncologic outcomes.
A new study finds that a drug called MVT-602 can improve fertility in women with reproductive health problems by targeting the kisspeptin hormone system. The drug's longer duration of action allows for less frequent dosing, offering improved treatment options for conditions such as polycystic ovary syndrome and hypothalamic amenorrhea.
A research team at Osaka University has discovered a new enzyme that helps make valuable bioactive saponins, including glycyrrhizin, a potent natural sweetener with antiviral properties. The enzyme discovery opens novel routes for producing these high-value products commercially.
A study analyzing data from 559 engineering and computer science students found that women earn less than men due to lower levels of self-efficacy. The authors suggest that career guidance, internships, and hiring practices that deemphasize self-confidence could help address the gender pay gap.
A longitudinal study led by researchers at the University of Central Florida aims to identify modifiable protective factors that may reduce the risk of suicide among young lesbian and bisexual women. The study will focus on experiences during key transitional moments in their lives, such as entering high school or college.
A study of 14,572 children found that antibiotic use during the first two years of life is associated with an increased risk of asthma, respiratory allergies, eczema, obesity and attention deficit hyperactivity disorder. Antibiotic exposure was also linked to metabolic diseases, immunological diseases and cognitive conditions.
A study reveals carbon dioxide from volcanic eruptions likely caused the end-Triassic mass extinction. The apparent increase in light carbon may have been caused by local sea level decline and microbial mats prior to the event.
A new species of Laoennea microsnail was discovered in a cave in Laos, with the species being 1.80 mm tall and named after Louis Renouard. The discovery highlights the importance of exploring biodiversity before it disappears, particularly in underexplored caves.
Researchers investigated COVID-19's effect on respiratory muscles in critically ill patients, comparing with non-COVID-19 cases. Severe COVID-19 was found to cause significant changes in the diaphragm, a crucial factor in patient outcomes.
A team of researchers has discovered a new species of Polynesian sandpiper, the Prosobonia sauli, from fossilized bones found on Henderson Island. The bird is believed to have gone extinct soon after humans arrived on the island, which archaeologists estimate happened no earlier than the eleventh century.
A study assessing US nephrology fellows' perceptions on home dialysis training found moderate preparedness for peritoneal dialysis and low confidence in home hemodialysis. The majority of trainees participated in continuity clinics and education, yet desired more focused teaching on PD and HHD.
A recent NOAA study published in Ecology and Evolution reveals higher interaction rates between spiny dogfish and Atlantic cod than previously observed. The study uses genetic testing to confirm cod presence in dogfish stomachs, finding that small cod are more likely to be well-digested, making identification challenging.
Researchers at the University of Illinois developed a new method that combines machine learning and physics to simulate turbulent flow, allowing for more accurate predictions in aerospace engineering. This method has the potential to improve design efficiency and reduce costs in industries such as air travel and spacecraft development.
The journal Invasive Plant Science and Management has launched a new series on the biology of invasive plants, focusing on emerging threats such as Pyrachantha augustifolia. The series aims to provide practical recommendations for intervening with invasive plant species and alerting biosecurity managers.
Researchers found that high-risk patients recovering from cardiac surgery who wore a continuous cardiac monitor had a 10-fold higher incidence of atrial fibrillation than those with usual care. This suggests that post-operative atrial fibrillation persists even after hospitalization, requiring prompt treatment and surveillance.
Researchers analyzed 16.7 million people's telemedicine and in-person visits during the 2020 COVID-19 pandemic to understand changes in outpatient care delivery. The study found that telemedicine compensated for declining volumes and geographic variation, suggesting a new model for healthcare delivery.
A new study found that rising temperatures make brown dog ticks more likely to choose humans over canines, elevating the risk of Rocky Mountain spotted fever infections. As climate change expands areas with high temperatures, public health authorities must be vigilant for increased disease risks.
A new study found that a Mediterranean diet can enhance stress resilience and slow nervous system aging in animal models. The study showed that the Mediterranean diet reduced sympathetic nervous system activity and cortisol levels compared to a Western diet.
A University of Gothenburg study found that continuous glucose monitoring (CGM) has favorable effects over several years, including a 4 mmol/mol decrease in average blood glucose levels and a 70% reduction in episodes with low blood sugar levels. Patients also reported improved comfort and reduced anxiety.