Researchers have identified a gene variant that contributes to unnecessary bone marrow biopsies in African Americans. The study found that 63% of African Americans carry the variant, which lowers white blood cell levels and is associated with Benign Ethnic Neutropenia.
Scientists have developed a new scheme to generate intense XUV pulses using near-infrared lasers, shrinking the need for large laboratory facilities. The setup produces high-intensity XUV pulses with potential applications in attosecond-pump attosecond-probe spectroscopy and nanoscale imaging.
The University of Massachusetts Lowell has recognized a group of K-12 students from Massachusetts and the Midwest for their artwork on climate change. The students' creations will be displayed on public buses to educate tens of thousands of passengers about extreme weather events.
Researchers found 556 novel markers of colorectal tumors with microsatellite instability, which are differentially expressed genes. These markers were identified by incorporating cell composition into their regression model, indicating a potential role in disease prognosis.
A new computer model has been created to understand plant energy storage, with lab experiments confirming its accuracy. The findings could improve crop resilience in challenging environments and help develop new plants for climate change.
Research shows that relacorilant enhances paclitaxel-driven apoptosis in various cancer cell lines and xenograft models, providing a basis for its potential as an adjunct therapy. The study's findings support clinical benefits observed with relacorilant addition to paclitaxel-containing therapy in ovarian and pancreatic cancers.
The ACTIV (Accelerating COVID-19 Therapeutic Interventions and Vaccines) workgroup has developed nine master protocols to evaluate therapeutic agents for COVID-19. The protocols aim to accelerate drug development and improve treatment outcomes for patients with COVID-19.
Researchers have successfully resurrected the extinct Gould's mouse, a significant finding given the high rate of native rodent extinction in Australia. The study revealed that the species' genetic diversity did not guarantee its survival, underscoring the rapid decline of populations in the face of invasive species, habitat destructio...
A RMIT-led international collaboration has achieved record-high electron doping in a layered ferromagnet, causing magnetic phase transition with significant promise for future electronics. Ultra-high-charge, doping-induced magnetic phase transition in Fe5Ge2 enables promising applications in antiferromagnetic spintronic devices.
A new study published in Chemical Senses found that patients who had their wisdom teeth extracted showed improved tasting abilities decades after surgery. The study challenges the notion that removal of wisdom teeth has only negative effects on taste and represents a significant finding in the field.
West Virginia University has launched a new initiative aimed at bridging the gap between science and policy, with a focus on addressing the state's most pressing water issues. The Bridge Initiative brings together over two dozen faculty researchers to translate their work into actionable policies for policymakers.
A new study by the University of Oxford and Environmental Change Institute found that evidence submitted in 73 climate lawsuits is behind state-of-the-art climate science. The study highlights the need for litigators to use more effective scientific evidence to overcome obstacles to causality.
A team of researchers has identified a protein complex that promotes breast cancer growth, which can be disrupted to hinder tumor development. Non-toxic peptides were developed to prevent the abnormal interaction between RBM39 and MLL1 proteins in breast cancer cells.
Researchers explore connections between preclinical and clinical modeling to develop unique animal-based disease models. Integration of active-targeting ligands and smart materials enhances nanomedicine functionalities, paving the way for new-concept nanoparticle-based drugs.
A new study by NYUAD researchers demonstrates a small molecule protein mimetic can reactivate the tumor suppressor protein p53, which is often mutated and deactivated in cancer. The treatment effectively shrinks tumors and prolongs survival with no noticeable toxicity to healthy tissue.
Researchers reviewed approaches to multi-material multi-photon micro/nano-printing, enabling targeted structures with diverse material properties. Automated systems are rapidly developing for combining multiple primary materials within a single machine tool.
A recent study using REST-meta-PD analyzed brain activity data from 15 PD patient studies, finding that up to 80% of voxels declared significant may not be replicable across datasets. The researchers propose a normative modelling method to improve reproducibility and generalizability.
Researchers from USTC realized the first on-chip valley-dependent quantum interference in silicon photonic crystals using harpoon-shaped beam splitters. The study demonstrates a novel method for topological photonics and its potential applications in complex quantum information processing.
A recent study found that coral reefs in the South China Sea adjust their trophic patterns in response to environmental conditions. By analyzing zooxanthellae density, nutrient levels, and light intensity, researchers discovered that corals can shift from autotrophic to heterotrophic modes of nutrition, enhancing their adaptability to ...
Research reveals that saturated fatty acids play a key role in forming memories, particularly in the amygdala region of the brain. The study found that levels of myristic acid, found in coconut oil and butter, increased significantly as new memories were formed.
Researchers developed sensitive SERS substrates via femtosecond laser processing for real-time sensing in biomedicine and microfluidic chips. Attomolar detection capabilities were achieved through synergistic enhancement effects, opening up new avenues for monitoring and sensing applications.
A recent study found that China's annual mean surface wind speed stopped weakening around 2014 and started strengthening, but stilling persists in certain regions. The reversal was driven by regional and seasonal variations.
The 70th Lindau Nobel Laureate Meeting has opened with a record number of participants, featuring discussions on topical issues such as future pandemics, gene editing, and climate change. The meeting aims to foster dialogue among scientists from around the world and promote sustainable scientific conduct.
Researchers propose a triple-cycle heat treatment system to improve the microstructure and performance of 3D printed titanium-molybdenum alloy human implants, achieving better biocompatibility and mechanical properties matching human bones. This method enables more widespread use of 3D printed implants in the biomedical field.
A new study from Uppsala University reveals that males play a crucial role in maintaining genetic health by eliminating harmful mutations. The research found that selective pressure on males leads to the purging of deleterious mutations, resulting in healthier genes and increased reproductive capacity.
The research team established a single lysosome mass spectrometry platform to analyze the metabolic heterogeneity of various lysosome types in cell aging. They found that each type of lysosomal subset exhibited distinct metabonomics changes, indicating lysosome type specificity in cellular aging.
Researchers at Columbia University School of Engineering and Applied Science have developed a computer vision technique that enables machines to predict human behavior with higher accuracy. The algorithm leverages higher-level associations between people, animals, and objects to make more intuitive predictions about future actions, ope...
A new study reveals that 16 out of 146 health-related APPGs in the UK received over £1 million in payments from pharmaceutical companies between 2012-2018. The researchers argue that a lack of transparency highlights potential conflicts of interests towards public policy, despite no evidence of wrongdoing.
A recent study identified 363 marine invertebrate RNA viruses from 58 samples, revealing high genetic diversity and elasticity. The findings suggest possible virus transmission across different ocean areas and host species, shedding light on the origin of hantaviruses.
Researchers at Tokyo Metropolitan University have discovered that disulfide bonds on certain amino acids stabilize tau protein, leading to its accumulation and triggering neurodegenerative diseases like Alzheimer's. The study suggests that targeting these chemical groups may lead to novel treatments to reduce or prevent tau accumulation.
The study suggests that revenues from emissions pricing should be distributed according to historical emissions, providing the greatest leeway for a consensual ambitious climate policy. This design can help overcome obstacles such as differing country sizes and wealth, ultimately strengthening EU climate policy.
ASU engineering researchers have discovered a new neural stem cell state that could be key to unlocking new methods of brain cancer treatment. The team found that the quiescent Neural G0 state is independent of a tumor's proliferation rate and can potentially be targeted for new drug treatments.
Scientists have created a way to harness discarded plant matter, such as corn stover, into ethanol and plastics with near-industrial efficiency. By helping yeast survive industrial toxins and converting toxic aldehydes into harmless compounds, the system enables low-cost production of biofuels.
LGBTQ youth experience daily stressors related to their multiple stigmatized identities, leading to greater negative emotions and associated mental health issues. The study found that minority stressors are associated with higher levels of negative affect on days when participants experienced more stressors.
Researchers developed a method to identify areas with smoother waters as indicative of microplastic presence, leveraging CYGNSS satellite data. This technique demonstrates the potential for tracking ocean microplastics from space.
A joint research paper by Professor Sungil Kim and Ph.D. student YongKyung Oh has been commended for excellence in the 2021 IISE Annual Conference. The team developed a real-time anomaly detection model using maritime big data, showcasing a technique to quantify uncertainty in anomaly detection.
Researchers created designed and biologically active 2-D and 3-D protein arrays using DNA-based assembly, maintaining structural stability and biological activity. The method has potential applications in structural biology, biomaterials, nanomedicine, and biocatalysis.
Research finds that actively addressing inequalities fosters social change when meeting the psychological needs of both groups. Meeting the needs of disadvantaged groups through empowerment and listening helps to bolster their interest in collective action.
The LIGHT-CAP project aims to develop new nanotechnology-enabled architectures for solar energy conversion and storage. Researchers will apply cutting-edge materials to build systems capable of absorbing sunlight, converting it into electric charges and storing the associated energy in a sustainable way.
Scientists at the University of Southampton have found that TNF receptor activation requires receptor clustering, but smaller clusters with higher density activate receptors better than larger ones. This discovery could guide future development of therapeutic antibodies targeting TNF receptors.
Researchers from Massachusetts General Hospital found that the BCG vaccine significantly lowers blood sugar levels in type 1 diabetics, with faster response times and greater changes in HbA1c for younger patients. The vaccine also restores gene expression in regulatory T cells over three years.
Researchers develop engineered yeast that can convert toxic cellulosic byproducts into ethanol and other chemicals, opening up a wider range of non-food feedstocks. The breakthrough could potentially substitute for 30-50% of petroleum used in transportation.
A new technology has been developed to reduce adverse effects of medical materials in the human body. The material can be loaded with therapeutic cells and deliver them to desired sites, mitigating inflammation and blood clots.
A recent study analyzed hospitalization and death rates related to COVID-19 before and after US states reopened their economies in 2020. The findings showed a significant increase in hospitalizations and deaths following state reopenings, indicating a need for continued public health measures.
A new UC Davis study confirms that SARS-CoV-2 contamination on hospital surfaces is unlikely to be infectious. The research used genome sequencing to detect the virus on surfaces and found that only a small percentage of samples were positive, suggesting that improved cleaning protocols may have reduced transmission.
Researchers found that non-native species are more successful in the less-diverse Pacific, where they outnumber native species by 30%, compared to the more-diverse Atlantic. Predation also played a crucial role in controlling invasive species, particularly in tropical regions.
Researchers from University of Tsukuba found a decrease in COVID-19-related house call services due to lower seasonal flu activity, but an increase in severe cases. Hospital capacity strains during the pandemic contributed to this trend.
Researchers at Tomsk Polytechnic University have successfully synthesized a unique molecule of verdazyl-nitronyl nitroxide triradical, boasting stable structure and high-temperature magnetism. The breakthrough could pave the way for innovative organic magnetic materials with potential applications in MRAM technology.
Researchers developed a low-cost way for backscatter radios to support high-throughput communication and 5G-speed Gb/sec data transfer using only a single transistor. This breakthrough enables scalable communication systems for IoT applications, including energy harvesting, smart home sensors, and agricultural tracking.
A new observational study found that Black and Latino children were significantly affected by COVID-linked multi-system inflammatory syndrome, with cardiac complications more common in critically ill patients. The study also identified distinct cytokine signatures and viral sequencing patterns, shedding light on the disease's demograph...
Antacids have been found to lower HbA1c levels by 0.36% and fasting blood sugar by 10 mg/dl in individuals with diabetes. However, taking antacids had no effect on the risk of developing diabetes in non-diabetic individuals.
Researchers at the University of Texas at Austin have developed a new version of optical tweezer technology that fixes the problem of overheating, making it easier to study biomolecules and diseases. The breakthrough uses cooled materials and thermophoresis to attract particles, protecting them from damage.
A new study uses machine learning to predict over 20,000 unknown virus-mammal associations, expanding our knowledge of zoonotic diseases. The model identifies bats and rodents as key hosts for emerging viruses, highlighting the need for targeted surveillance and mitigation strategies.
A nationwide study evaluates a targeted intervention aimed at transforming e-cigarettes from a maintenance product to a tool for smoking cessation. The research shows that the intervention produced smoking abstinence rates about 5-10 percentage points higher than those who received no intervention.
UNIST students were selected as the final winning team at the 2021 JunctionX Seoul hackathon with their mobile game 'My Running Mate, Zombie'. The team took only three days to build the game from scratch using feedback from embedded motion sensors and cloud computing platforms.
Research reveals that cocoa agroforestry systems can support diverse bird populations by maintaining canopy cover from native trees. Intensified, low-shade cocoa monocultures lead to sharp declines in bird diversity. The study emphasizes the need for sustainable agroforestry practices to conserve habitats and biodiversity.
Researchers at NIST developed a method using radio signals to image hidden and speeding objects, enabling real-time imaging around corners and through walls. The technique has potential applications in public safety, tracking hypersonic objects, and improving space debris detection.
A recent study examined the association between COVID-19-related childcare facility closures and employment status of women and men with children. The research found that childcare closures led to increased unemployment rates for both men and women, but women were more likely to experience a decline in employment opportunities.
Chemists at Scripps Research have developed a new method for adding hydroxyl groups to organic molecules using a shape-shifting catalyst. The breakthrough eases the process of modifying existing molecules for valuable applications such as improving drug potency and duration. The new method has been demonstrated on various existing drug...
A new study found that 82% of Americans support paid maternity leave, similar to 86% in 26 wealthy nations. However, Americans are less supportive of government funding and prefer shorter leave times. Worldwide, people generally want longer leave periods and government funding.