Researchers at Linköping University have developed new resin acid molecules with antiseizure effects, opening a potassium ion channel that can prevent epileptic seizures. The molecules also show less effect on smooth muscle, reducing undesired side effects.
During lockdowns, the 20-40 age group slept more, walked less and felt unhappier compared to older subjects. The study suggests that women were more affected by lockdowns, with increased stress and reduced social interactions.
A recent paper examines the critical period before river regulation began, revealing that erosion of the upper Atchafalaya and dredging of the lower Mississippi contributed to increased water flow. The research aims to better understand river channel dynamics and inform management decisions to preserve Louisiana's coastline.
Researchers at Kennesaw State University investigated how various types of face coverings affect students' understanding of their teachers. They found that some masks performed well acoustically, but not as effectively against virus transmission.
A new global analysis reveals that greenhouse-gas emissions from food systems have long been systematically underestimated, with the equivalent of 16 billion metric tons of carbon dioxide produced in 2018. The study highlights the need for integrating research with efforts to reduce emissions and emphasizes the importance of considerin...
Researchers found a significant increase in mortality rates among rural residents aged 25-64, with a 12.1% rise in age-adjusted mortality rates. Death rates among Black individuals remained higher overall, but the gap with white individuals halved.
CooperVision presented over 20 papers and posters on presbyopia, soft toric lens fitting, and myopia control. The research highlights the importance of patient input, toric lens performance attributes, and children's acceptance of myopia control interventions.
Researchers found associations between COVID-19 infection rates and race/ethnicity, with varying patterns over time. Food insecurity was also linked to increased COVID-19 risk, particularly among vulnerable populations.
A new forecasting method has been developed to improve TC intensity forecast skill, providing more precise 5-7 day forecasts for coastal regions of East Asia. The logistic growth equation-based approach outperforms conventional methods, offering potential for forecasting rapid intensification and weakening.
A recent study found that sleep timing and duration are associated with an increased risk of cannabis use and binge drinking among teens and young adults. Late-night preference predicted a greater likelihood of any cannabis use, while later sleep timing on the weekend predicted more severe binge drinking.
Researchers have identified a potential new treatment for ALS using motor neurons created from ALS patients. The high-throughput platform confirmed two known targets and found an existing class of drugs that could reduce hyperexcitability, a key feature of the disease.
A live-cell screening strategy identified Kv7.2/7.3 as a key target for treating hyperexcitability-induced neurodegeneration in ALS patients. QurAlis' therapeutic candidate QRL-101 (QRA-244) shows promise in decreasing spinal and cortical motor neuron excitability.
A new study at Lund University tracked meteorite flux to Earth over 500 million years, revealing a stable flux contrary to current theories. Researchers analyzed sedimentary rocks and extracted chromium oxide grains from nearly 10,000 meteorites.
Researchers have developed a method for breaking camouflage that allows civilians and military personnel to identify hidden targets with high accuracy, even in complex scenes. The technique has been shown to be effective even when participants are given only a short viewing time.
A systematic review of treatments for depression in people with coronary heart disease suggests that exercise is the most effective short-term treatment. The study also found that combination treatments, including antidepressants and psychotherapy, had stronger effects than other interventions.
A new analysis from Imperial College London suggests that countries investing in new coal mines and exports risk losing billions of dollars as the world shifts away from fossil fuels. Transitioning to a sustainable pathway by 2040 could save $10 billion per year globally, while avoiding job losses and economic instability.
A research team led by the University of Göttingen has created tiny gas bubbles with a radius of a few thousandths of a millimeter using laser pulses, observing their expansion and shockwaves. The team used holographic flash imaging and X-ray laser pulses to capture data and images, providing insights into cavitation processes.
Experts call for global regulation to prevent unproven stem cell treatments from putting patients' lives at risk. The authors propose establishing an advisory committee on regenerative medicine and promoting harmonization among regulatory standards.
A global assessment report by UNESCO's Intergovernmental Oceanographic Commission found that reported Harmful Algal Bloom (HAB) events have increased in some regions, while decreasing or holding steady in others. The study highlights the need for more research on the linkages between HABs and growth of the aquaculture industry.
Most São Paulo state cities have limited capacity to adapt to climate change, with metropolitan areas scoring higher according to the Urban Adaptation Index. Cities must develop strategies to reduce greenhouse gas emissions and contribute to global efforts to mitigate climate change.
A 14-day performing arts program reduced implicit cognitive biases against physical illnesses, according to a University of Barcelona study. The program combined scientific training with theatre performance and showed that participants' reaction times decreased after the experience.
Researchers discovered that hormone biomarkers from the placenta can identify women at risk for pregnancy complications, which affect around one in ten pregnant women. The study found that these biomarkers are present from the first trimester and can lead to earlier diagnosis and treatment.
A population-based study published in JAMA found no association between maternal influenza vaccination during pregnancy and adverse early childhood health outcomes. The study followed over 28,000 children from birth to 3 ½ years old, indicating that flu vaccination during pregnancy does not increase the risk of immune-related or non-im...
Researchers found that during rest, the brain rapidly replays compressed versions of previously practiced activities, strengthening memories and improving subsequent practice sessions. This study suggests that wakeful rest plays a crucial role in learning new skills and may be used to facilitate rehabilitation from stroke.
A study found that maintaining tree diversity can prevent a significant reduction in terrestrial primary productivity, which could have social and economic benefits for communities. Countries with high carbon emissions are incentivized to mitigate climate change by preserving tree diversity.
Rangarajan aims to develop a novel computational framework to understand the molecular level of catalytic transfer hydrogenation, a promising approach for safe and cost-effective biomass conversion. The technique could lead to more compact, modular processes with near-ambient temperatures and pressures.
A new study by Associate Professor Daniel Russo highlights the importance of strengthening developers' social and technical skills for Agile project success. The study also emphasizes the critical role of top management commitment in providing an adequate organizational setting.
A research group at KAIST successfully produced seven natural rainbow colorants, including carotenoids and violacein derivatives, using engineered Escherichia coli strains. The strategies developed can be applied to the efficient production of other industrially important natural products.
Researchers co-led by Professor Wang Xunli discovered a structure link between a glass solid and its crystalline counterpart, finding that both forms share the same building block. The team also concluded that connectivity between clusters distinguishes the crystalline and amorphous states.
A recent study by the University of Cambridge found that individuals who are more concerned about contracting COVID-19 tend to be more disapproving of others' wrongdoings. The researchers suggest that concerns about health and safety shape morality, leading to non-rational judgments.
A new study found that youth with a history of foster care have self-identified dental needs, including issues with pain, and less access to a dentist to address these needs. Approximately 44% of youth with a history of foster care reported at least one dental problem.
A new study by Staffordshire University highlights the devastating impact of COVID-19 on Stoke-on-Trent's residents, with thousands turning to foodbanks for welfare support. The report calls for comprehensive action to address poverty, including benefit take-up campaigns and a Scandinavian-style employment and training model.
Researchers at Virginia Tech have identified a novel gene, Per2AS, that controls the sleep/wake cycle in mice, revealing the importance of non-coding genes in regulating biological processes. The study's findings could lead to breakthroughs in understanding internal body clocks and their role in various diseases.
Plant diseases can spread globally without borders, threatening food security. Researchers call for a One Health approach to safeguard staple crops from pandemic outbreaks.
Researchers found that boat noise significantly reduces communication distance and coordination in duetting toadfish, impacting their mating habits. Human water traffic effectively drowns out their serenades.
A study of over 700,000 TBI patients found that those with sleep disorders had a 25% higher risk of developing dementia. The risk was similar for male and female patients, highlighting the importance of targeted awareness about sleep disorders in TBI patients.
Researchers have developed a technology to manipulate viruses synthetically, allowing for rapid analysis and mapping of new potential virus variants. This innovation enables scientists to mimic natural selection processes safely in a controlled laboratory environment.
En'Urga will design and evaluate a hyperspectral imager to provide spatially and temporally resolved gas concentrations and temperatures in turbulent reacting flows. The technology aims to improve propulsion systems, aero engines, and associated technologies for NASA's John C. Stennis Space Center.
Researchers at ETH Zurich have developed a new approach to prove the robustness conditions of certain quantum-based machine learning models, guaranteeing reliable results. The team's work explores protection against errors and hackers, paving the way for more accurate and trustworthy quantum machine learning applications.
A recent study suggests that improving economic conditions can reduce radicalization efforts, but trying to render people psychologically less susceptible can backfire. Conspiracies have become a powerful tool for far-right groups to manipulate public discourse and drive the growing radicalization of average Americans.
A preclinical study suggests that senolytic drugs can significantly reduce mortality and severe disease in elderly people infected with SARS-CoV-2. The study found that treating older mice with senolytic drugs increased their survival rate from nearly 0% to 50%, reducing cellular senescence and inflammatory markers.
RedHill Biopharma has completed enrollment and randomized the last patient in its global Phase 2/3 study of orally-administered opaganib for treating severe COVID-19. The study captured outcomes such as breathing room air without oxygen support by Day 14, hospital discharge time, and intubation rates.
A new model developed by Rensselaer Polytechnic Institute found that coordinated travel restrictions could have reduced the spread of COVID-19, with some restrictions reducing arrival times by up to 10 days and global infections by 6 million.
Researchers at the University of Cambridge have developed a new technique that enables the creation of ultra-bright, flexible LEDs with improved efficiency and low cost. By swapping one out of every thousand atoms, they tripled the luminescence of halide perovskites, which could be useful for low-cost printable and flexible LED lighting.
Researchers developed classification criteria using machine learning to standardize language and identify characteristics that distinguish each disease. The criteria have been validated with over 90% accuracy within uveitic class.
Researchers at Tel Aviv University discovered a mechanism through which 'good' viruses can target and destroy 'bad' bacteria, using a bacteriophage protein to exploit the bacterial DNA's need for repair. This finding may lead to new tools to combat antibiotic-resistant bacteria.
A study found that women in family-owned businesses are often discouraged from developing leadership skills and pursuing entrepreneurial careers. The research revealed that 78% of sons pursued entrepreneurial careers, while only 7% of daughters gained an entrepreneurial education or started a business.
Two new papers investigate massive plankton blooms with vastly different potential impacts on ecosystems. The studies reveal unexpected productivity hotspots in the Mid-Atlantic Bight, fueled by Gulf Stream water upwelling, and a huge bloom of Phaeocystis pouchetii on the New England continental shelf.
Researchers found dapagliflozin reduced the risk of progressive kidney disease by half in FSGS patients over a 2.4-year period, with good tolerability and safety. The medication stabilizes renal function and improves clinical outcomes in patients with type 2 diabetes and concomitant kidney damage.
A recent study reveals that socially isolated kids face different risks than those who experience peer rejection. The researchers found that socially isolated kids are more likely to exhibit internalizing behaviors like shyness and withdrawal, while those in the rejected group are more prone to aggressive behavior.
Researchers have discovered that pre-trained phages can increase their ability to fight bacterial infections, delaying the onset of antibiotic resistance. This breakthrough uses evolutionary training to improve phage potency against deadly bacteria.
Researchers apply mathematics to real-world data, finding popular people tend to be friends with each other, while less popular people connect with others of similar status. The study reveals around 95% of variation in social networks can be explained by these two factors.
The pandemic led to increased consumption of unhealthy snacks, desserts, and sugary drinks. Many Americans worried about food availability and safety, with lower-income households more concerned. Online grocery shopping became a key trend during the pandemic.
A study found that using ultrasound to monitor lung congestion in hemodialysis patients with high cardiovascular risk improved patient outcomes. The technique reduced episodes of decompensated heart failure and cardiovascular events by 37% and 63%, respectively.
A team of scientists led by Yoshiaki Nakamura successfully reversed male infertility in mice through a new method that artificially tunes the fate of sperm stem cells. The results, published in Cell Stem Cell, show great promise for future applications in regenerating human sperm after cancer treatment and preserving genetic diversity.
A recent study found that non-tiered customer loyalty programs create a more sustainable customer base and reduce customer fall-off and turnover. The program's effectiveness lies in its ability to nurture long-term relationships with customers, rather than increasing frequency or spending.
A new study found that climate warming will increase carbon loss in Canadian peatland by 103 per cent due to changes in soil temperature and photosynthesis. This will lead to a strong positive climate feedback loop, where peatlands release greenhouse gases contributing to further climate warming.
Researchers found evidence of intensive land use for farming and fishing over 3,500 years ago in the Llanos de Mojos region of Bolivia. This discovery counters the often-held notion of a pristine Amazon before Europeans arrived and provides new insights into the history of culturally diverse but understudied cultures.
Physicist Generalized the Measurement Postulate in Quantum Mechanics, explaining state collapse and partial measurement, supported by the WISE interpretation and delayed choice experiment. The paper proposes a new understanding of wavefunction and its relation to the quantum system.
Researchers restored gut microbes missing in early life dysbiosis and prevented colitis in mice by adding a single strain of Bacteroides sp. CL1-UC. This finding highlights the importance of early childhood exposures on health throughout lifetime.