SUTD researchers created a novel modeling technique to reduce risk of permanent device damage in resistive memory devices. The new toolkit can predict current accurately, improving prediction accuracy by around ten times.
Researchers from the University of Groningen and Spain developed a method to train AI systems using distractions to improve image recognition. By analyzing how deep learning systems process images, they found that forcing the system's focus towards secondary characteristics can lead to better performance.
Repurposed drugs for COVID-19 have yielded no effective treatments despite billions spent. Direct-acting antivirals are recommended to avoid false positives and patient risks. The scientific community emphasizes thoroughness in drug screenings, highlighting the importance of structure-activity relationships.
Research from UNSW Sydney found that unexpected uncertainty prompts people to adjust their behavior, even if it's not the best strategy. In contrast, gradual changes in uncertainty do not lead to significant behavioral shifts. The study suggests that understanding how people react to uncertainty can help overcome inertia and promote su...
Researchers mapped the molecular mechanisms of primate hippocampal aging, identifying key cell types and molecules affected by age. The study provides a valuable resource for diagnostic biomarkers and therapeutic targets for neurodegenerative diseases.
Long Covid's chronic symptoms, including extreme fatigue and brain fog, result in considerable socioeconomic disability. The lack of formal recognition and diagnostic criteria for Long Covid hinders our understanding of the syndrome, its potential drivers, and its impact on mental health.
Researchers have discovered that the electrolyte penetrates silicon everywhere, forming pockets of SEI that disrupt electron pathways. A coating approach is proposed to preserve the integrity of silicon in the presence of electrolyte, potentially revolutionizing high-capacity lithium-ion batteries.
The American Heart Association has launched a $20 million research initiative, RESTORE Network, to address health equity in preventing hypertension. The project aims to test multiple strategies to overcome social determinants of health and provide better access to care for Black communities.
Neuroscientists used artificial intelligence to disentangle the relationship between perception and memory in the human brain. A novel computational framework predicts neural responses in the primate visual system, resolving decades-long debates over the role of the medial temporal lobe (MTL) in perception.
Researchers found that longer breaks between learning events lead to more stable activation patterns in the brain, allowing for better memory retention. This study provides insights into the neuronal processes behind the spacing effect, suggesting that taking breaks can slow down learning but improve long-term memory.
Researchers developed a machine learning tool, BoostDM, that evaluates the potential contribution of mutations in genes to cancer development. The tool helps understand how tumors are caused at the molecular level and can facilitate medical decisions regarding therapy.
A high-status Bronze Age woman and her twins were found in a Szigetszentmiklós urnfield cemetery, with remains indicating she was 25-35 years old at death. Strontium analysis suggested she was born elsewhere and moved to Hungary between ages 8-13.
A study from McGill University and France uses AI to identify factors predicting suicidal behavior in students, finding self-esteem as a major predictor. Approximately 17% of students exhibited suicidal behaviors, highlighting the need for large-scale screening tools.
Researchers found that targeted behavioral science messages significantly increased COVID-19 vaccination registration among healthcare workers. The study showed a substantial increase in vaccine uptake after receiving personalized email nudges.
Researchers analyzed Neandertal and Denisovan genomes to identify blood groups, confirming their African origin and Eurasian dispersal. The study also found evidence of low genetic diversity and possible demographic fragility, shedding light on the disappearance of Neandertals.
Researchers found that a protein activator clamps down the active center of GTPase Ran, allowing efficient hydrolysis. This discovery may lead to the development of cancer drugs blocking this process.
Lobular breast cancer patients often experience recurrence or metastasis despite hormonal therapies. CU Cancer Center researcher Matthew Sikora is studying the role of MDC1 in this subtype, finding it linked to estrogen receptor activity and potentially a novel target for treatment.
Researchers discovered that a protein called VDAC2 plays a key role in regulating calcium signaling within heart cells, which can help prevent chronic heart failure. Targeting this protein with drugs or therapeutic treatments may eventually alleviate heart failure.
Researchers developed magnetic, biodegradable nanomaterials that reduced the likelihood of mice fathering pups for at least 30 days. The nanoparticles were non-toxic to cells and gradually eliminated from the body.
Scientists at UCLA Jonsson Comprehensive Cancer Center have discovered that removing the RNA-binding protein IGF2BP3 selectively targets cancer cells while leaving healthy cells alone. This finding holds promise for the development of targeted therapies for cancers with high levels of IGF2BP3.
A new study challenges the effectiveness of current conservation efforts in protected areas, suggesting that 'saving' biodiversity may not be accurately measured. The study's lead author argues that measures such as expanding protected areas and establishing national parks do not necessarily translate to real progress in conservation.
Researchers have found that improved learning processes are associated with reduced symptoms of depression. By using brain imaging and mathematical modeling, the team identified distinct paths to depression symptoms and proposed a new approach for treating clinical depression.
Researchers found that feeding bumble bees caffeine improves their ability to recognize specific flower odors and remember the location of nectar-rich flowers. However, this effect is short-lived, as the bees quickly adapt and lose their preference for caffeinated flowers.
The MIT Press has partnered with Jisc to provide central licensing and invoicing for Direct to Open, a framework that moves books from a market-based model to a library-supported open access model. Libraries committing to D2O before September 30 will earn exclusive benefits, including term access to an archive of gated titles.
A randomized trial found that individually addressed email reminders designed with behavioral science principles increased COVID-19 vaccination registration among healthcare workers, compared to those who did not receive an email. The emails led to more than twice as many registrations within three days.
A group of six leading Alzheimer's experts has made the first recommendations for the appropriate use of aducanumab (Aduhelm), a newly approved treatment for early Alzheimer's disease. The guidelines aim to provide clinicians with greater clarity and specificity in using the new treatment.
Researchers found hybrid electric vehicles have twice the vulnerability to supply chain disruptions as gas-powered models, due to volatile battery prices and scarce materials. Long-term supplier contracts and material substitution can mitigate these risks as manufacturers ramp up EV production.
Studies reveal that chronic viral infections can lead to T cell exhaustion, where immune cells become dysfunctional and unable to respond effectively. Researchers discovered epigenetic scars on exhausted T cells, which may prevent their recovery even after infection clearance.
Researchers at Waseda University have developed a novel mechanism for inducing high-speed bending in thick crystals using the photothermal effect, enabling rapid actuation and simulation. This breakthrough has significant implications for flexible robotics, actuators, and soft robotics.
A team of scientists used hybrid machine learning methods to predict the incidence of heatstroke in Japanese cities. They achieved a high level of accuracy using publicly available information such as demographics and weather forecasts.
A phase 2 study found that riluzole slowed brain metabolic decline and improved cognitive performance in patients with mild Alzheimer's disease. The drug targets glutamate dysregulation thought to contribute to the development of Alzheimer's.
A recent study by the University of Bonn highlights the psychological consequences of Covid-19 in healthcare workers, with over 20% experiencing symptoms of depression or anxiety. The researchers found that a strong sense of coherence and social support were key protective factors against mental strain, emphasizing the importance of ti...
Researchers are exploring autonomous discovery techniques to reduce data required for scientific discovery, enabling faster and more efficient exploration of multi-dimensional parameter spaces. The field is gaining traction across various disciplines, including physics, chemistry, biology, materials science, and more.
Research predicts that climatologically wet regions will get wetter on average, but also swing widely between wet and dry conditions. This increased rainfall variability could lead to more extreme weather events impacting crop yields, river flows, and infrastructure resilience.
This study analyzed the risk of SARS-CoV-2 infection among hospital healthcare workers and found that those with certain underlying conditions were more susceptible. The study also identified specific patient populations at increased risk, highlighting the need for targeted interventions to prevent transmission.
Immunology researchers from The University of Queensland have identified UMAP as a powerful tool for analyzing large patient datasets. This method performed significantly better than PCA in reducing the complexity of big data, enabling accurate patient stratification and clustering. The findings could lead to the adoption of targeted t...
Rice University bioengineers are developing an insulin-producing implant to regulate blood glucose levels in Type 1 diabetics. The implant uses human stem cells and 3D printing to mimic the natural behavior of the pancreas, with the goal of achieving consistent target blood glucose levels.
Researchers have made the first direct observation of light from behind a black hole, confirming a key prediction by Einstein's theory of general relativity. The discovery was made using X-rays emitted by a supermassive black hole at a galaxy 800 million light-years away.
A Cornell-led study reveals that certain metals, like copper oxide-based superconductors, exhibit chaotic electron behavior governed by the Planckian limit. This limit dictates an upper bound on collision rates, which researchers have accurately measured for the first time.
Researchers at the University of Bonn have developed a novel method for fast 3D microscopy, allowing for precise tracking of non-labeled biological structures. This breakthrough enables new insights into cellular dynamics and has potential applications in fields such as bionics and understanding causes of infertility.
A meta-analysis found that people with metabolic syndrome are 46% more likely to have a second stroke than those without, with low HDL cholesterol being an independent risk factor. Additionally, individuals with metabolic syndrome were 27% more likely to die during the study.
Researchers found that farnesol prevents loss of dopamine neurons and reverses behavioral deficits in mice, indicating its potential as a drug treatment for Parkinson's disease. The compound blocks the PARIS protein, which is involved in the progression of the disease.
The number of unemployed people with and without disabilities has stabilized, but at levels higher than pre-pandemic levels, indicating many people have not yet returned to the labor market. Public health concerns, such as the spread of the delta variant, warrant caution and may lead to increased furloughs.
Researchers at the Technion- Israel Institute of Technology have developed a revolutionary imaging technology that breaks through limitations of current single-pixel imaging (SPI) systems. The new technology, which uses an unprecedented high frequency of 2.4 MHz, enables the creation of high-quality images in record time.
A study by Anglia Ruskin University found that younger people with diabetes are significantly more concerned about COVID-19 risks and have a higher likelihood of reporting worries. Social support from family, friends, and healthcare teams plays a crucial role in managing these concerns.
Researchers analyzed country-level health systems capacity and socioeconomic characteristics to understand delays in implementing COVID-19 non-pharmaceutical interventions. Lockdowns significantly reduced physical mobility, while national school closures had no significant impact.
Researchers identified 19 gluten-like proteins in ryegrass, a common weed contaminating gluten-free crops. The study aims to develop tests to detect these proteins in food products.
A new imaging technique developed by the Skala Lab can predict the efficiency of cardiomyocyte differentiation from human pluripotent stem cells, providing a non-invasive quality control method. The technique uses autofluorescence to measure metabolic activity and has been shown to be accurate in predicting outcome with high consistency.
A new study by University of Arizona researchers found that both multicellularity and sexual reproduction helped explain the rapid proliferation of animal, plant, and fungal species. The study suggests that multicellularity is actually more important than sexual production in driving diversity.
A study published in Nature Medicine found that combining different COVID-19 vaccines boosts the immune response by up to ten times. The research team discovered that a combination of AstraZeneca and BioNTech vaccines or double doses of BioNTech vaccination yields better results than a double dose of AstraZeneca vaccine.
Researchers discovered that the majority of the spike protein degrades within 24 hours, providing insights into infection and vaccination processes. The study also shed light on the role of key host factors in cell-to-cell fusion, a crucial aspect of COVID-19 pathology.
Certain floral bacteria can induce pollen germination, allowing them to access nutrients. This discovery could have implications for the biology of pollen digestion and its impact on pollinators.
Researchers use 3D visualization to analyze bioplastic granule accumulation in bacteria, providing insights into sustainable plastic substitutes. The study found distinctive differences in PHA granule density and localization between microorganisms.
Researchers found that mice can make fine visual discriminations between slightly different lines, suggesting a more complex decision-making process than previously thought. The study's findings highlight the importance of considering non-perceptual biases in understanding animal behavior and decision-making strategies.
The study explores how adult women experience acne's influence on their lives, finding it affects self-esteem and relationships. Adult women describe the negative emotional impacts of acne on their daily lives.
A study by the University of Vienna found that attachment style is a key predictor of high relationship quality during times of crisis. Participants with secure attachment styles had higher relationship quality than those with anxious or avoidant styles.
A systematic review and meta-analysis found individuals with preexisting mood disorders are at a higher risk of COVID-19 hospitalization and death. This suggests that those with preexisting mood disorders should be categorized as an at-risk group on the basis of a preexisting condition.
A new study suggests that older adults, particularly women and those in fair or poor health, are more likely to experience worsened mental health symptoms during the pandemic. The study recommends screening for depression, anxiety, and sleep problems and connecting participants to treatment resources.
A study of 692 female surgeons found that nearly half experienced major pregnancy complications, including miscarriages and preterm birth. The researchers call for policy changes to support pregnant surgeons and change the culture surrounding childbearing.
The University of Huddersfield's Centre for Precision Technologies will receive £3m funding to drive advancements in machinery design and performance. The project aims to grow the UK's advanced machinery capability to a £2 billion export capacity within ten years, creating over 30,000 high-value manufacturing sector jobs.