Centivax has entered into a strategic partnership with the US Naval Medical Research Center to develop Centi-B9, a broad-spectrum injectable antibody therapeutic and prophylactic for COVID-19. The Phase I trial aims to demonstrate safety and pharmacokinetics of Centi-B9 in healthy volunteers.
Twice a day, a faint layer of metals sinks down through the atmosphere at 90 miles high above Boulder, Colorado. The discovery provides a window into the high-altitude region where interactions between the sun, earth, and magnetic field can create conditions for surface life to thrive.
Researchers at the University of Bern found that most plastic waste does not end up in open ocean, but instead remains near coastlines or on beaches. The study suggests that regions with large sources of plastic waste, such as Southeast Asia and the Mediterranean, are disproportionately affected.
Researchers from the University of Pittsburgh have developed a new particle-free silver microgrid conductor that surpasses traditional indium tin oxide (ITO) in flexible high-performance transparent electrodes. The microgrids demonstrate better transparency, lower roughness, and mechanical durability.
Researchers discovered that primary miRNA precursor forms are highly expressed in cell-type-specific manner, while mature miRNAs dominate common to all cell types. The study also uncovered microRNA-messenger RNA networks driving cell-type-specific responses.
Researchers discovered hexagonal boron nitride's fracture resistance is about 10 times higher than graphene's, due to slight asymmetries in its atomic structure. This finding opens up new possibilities for fabricating tough mechanical metamaterials through engineered structural asymmetry.
Researchers at NYU Tandon have developed a method to speed up the doping process of perovskite solar cells using carbon dioxide, increasing efficiency by 100 times. This process also captures CO2, making it a potential solution for reducing greenhouse gas emissions in commercial solar cell production.
Scientists at the University of Houston have demonstrated giant flexoelectricity in soft elastomers, paving the way for improved robot movement range and self-powered pacemakers. The breakthrough could also enable human-like robots to perform physical tasks with greater flexibility.
The OSA Foundation and Corning Incorporated have awarded three women graduate students with $5,000 scholarships to support their research in optical communications and networking. The recipients will present their work at the Optical Fiber Communication Conference and Exhibition.
The US Army has partnered with teams led by the University of Maryland to accelerate AI development and deployment for safe and effective capabilities. The collaboration aims to reduce human workload and risk in complex environments, such as search-and-rescue operations.
Researchers at Texas A&M University have developed a new class of hydrogels that can be controlled by light, enabling precise drug delivery and regenerative medicine treatments. The hydrogels are responsive to near-infrared (NIR) light, which has a higher penetration depth than other light sources, allowing for more effective therapy.
A team of researchers has successfully controlled the magnetic state of two-dimensional van der Waals magnets using light, enabling efficient data storage and fast data processing. By inducing 'magnetic anisotropy' with ultrashort pulses of light, the scientists can manipulate the material's magnetic properties on demand.
A new study published in PLOS ONE demonstrates the potential of machine learning to identify high-risk patients with pancreatic cancer up to 2 years before diagnosis. The algorithm achieved high sensitivity and specificity rates, identifying 41% of patients under 60 as high risk and 72% of those diagnosed as having a detectable risk. T...
A study by SMU Associate Professor Rencheng Wang found that short selling reduces opportunistic insider sales by 11% in pilot firms, deterring unethical behavior. This suggests that short sellers can play a positive role in capital market development and governance reforms across different institutional environments.
Researchers at UNIGE create 3D spheroidal tumor models incorporating tumor cells and patient-specific immune cells to test treatment efficacy. This innovative approach enables personalized treatment options, potentially reducing reliance on animal experiments.
A study of university students found that despite optimistic initial expectations, women tended to decrease their expected wages after being informed about the actual wages of similar graduates. In contrast, male students increased their expected wages under the same conditions. The study suggests a persistent gender gap in wage expect...
Researchers discovered a surprising paradox: as emotional expressions increase in intensity, they become more ambiguous to infer meaning from, with maximal intensity leading to decreased legibility. This challenges prevailing theories of emotion and opens new avenues for understanding affective experience and communication.
A study by SMU researchers found that corporate social responsibility (CSR) activities have a positive impact on future operating performance, but only in tangible asset-intensive industries such as manufacturing and utilities. For companies in intangible asset-intensive sectors like technology, there is no significant beneficial effect.
A computer modeling study found that declining fish biodiversity can lead to a decrease in essential nutrients like zinc and iron, exacerbating existing health issues like anemia. The study's findings have significant implications for food security and fisheries sustainability worldwide.
Scientists have developed a new approach to improve hydrogen transport in solids, enabling faster movement of negatively charged hydrogen 'anions' at lower temperatures. The breakthrough could lead to more sustainable sources of energy and practical applications in electrochemical devices.
Experts recommend making COVID-19 jabs free in India to boost uptake and curb the death toll from the infection. The country is facing a critical shortage of hospital beds, ICU beds, medicines, ventilators, oxygen, and healthcare staff due to high infections.
Researchers found COVID-19 risks higher in older, diabetic patients with higher community rates and larger clinics. Risks were lower in clinics with more side rooms and mask policies for asymptomatic patients.
A research team led by Jerica Berge will examine the effectiveness of real-time intervention methods, including ecological momentary intervention and home visiting, to improve family meal quality and reduce childhood obesity disparities. The five-year NIH grant aims to create a new model of treatment for primary care settings.
Researchers analyzed CT scans of nearly every living amphibian genus to reveal that frogs have lost teeth over 20 times during their evolution. The study found a correlation between the absence of teeth in frogs and a specialized diet on small insects.
Researchers tracked mobile phone data from millions of users in US metropolitan areas, finding that lower-income neighborhoods had significantly less time at home during the lockdown. Education level also played a role, with higher-income neighborhoods and those with more college degrees spending more time at home.
Researchers found that selective serotonin reuptake inhibitors can reduce deterioration of intellectual abilities in individuals with a microdeletion of chromosome 22. The study suggests a potential neuroprotective effect and opens up new research possibilities.
A new study led by Kumi Kuroda at RIKEN Center for Brain Science identified the calcitonin receptor as a crucial brain protein driving nurturing behaviors in mice. The research found that this protein motivates mothers to care for their infants, suppressing self-interest and risk-taking behaviors.
Kristin Morell, a UC Santa Barbara Assistant Professor, has received the National Science Foundation's prestigious CAREER award. The award will fund her research on plate tectonics and provide opportunities for underrepresented students to get involved in geoscience through internships and workshops.
Researchers at Children's Hospital of Philadelphia have developed a proof-of-concept treatment that can elevate adult and fetal hemoglobin levels simultaneously. The approach combines two tactics into a single gene therapy vector, which has shown promising results in vitro.
Researchers at NUS have developed a novel technique called solid phase synthesis-flow (SPS-flow) that automates the production of small-molecule pharmaceutical compounds. The method combines continuous-flow synthesis and solid-supported synthesis to produce target molecules with higher yields and structural diversity.
Researchers developed a novel approach to mitigate electromigration in nanoscale electronic interconnects by coating copper metal interconnects with hexagonal boron nitride. This innovation enables further scaling of device density and progression of Moore's Law, leading to improved device efficiency and decreased energy consumption.
A new study by Chinese Academy of Sciences researchers has revealed diverse magnetic field morphologies in Solar-type star-forming cores in the Taurus B213 region. The findings contradict expectations based on theory that magnetic fields regulate star formation.
A major Swedish forest fire in 2014 led to a significant loss of carbon and nutrients in the affected areas. Water quality in watercourses quickly returned to normal, while forested areas continued to lose carbon for many years after the fire.
Researchers found that early risers sleep an average of 1.1 hours longer on morning shifts, while night owls sleep two hours longer on evening shifts. Early risers also took more naps prior to their night shifts, compensating for their shorter nighttime sleep.
Researchers from SWOG presented results on several studies, including S1216 and S1404, which showed promising findings for patients with prostate and melanoma cancers. Additionally, secondary analyses from S0809 and S1200 revealed benefits of adjuvant chemoradiation and acupuncture for certain cancer types.
A mathematical simulation by researchers at UNC Health Care shows that non-pharmaceutical interventions like mask-wearing and physical distancing can help prevent COVID-19 spikes as vaccines are distributed. The study found that widespread vaccine adherence and adherence to precautions can lead to a sustained decline in new cases.
A study found that malaria parasite Plasmodium vivax accumulates in the spleen to a greater extent than its relative P. falciparum after infection. Imaging techniques revealed increased glucose metabolism in the spleen of participants infected with P. vivax.
Researchers found that table corals can recover habitats on the Great Barrier Reef at a rate 14 times higher when abundant, compared to reefs without them. The study highlights the importance of protecting table corals to promote reef recovery and biodiversity.
Researchers discovered that neural activity underlying visual signals can ignite and feed tumors in young children with neurofibromatosis type 1. The study found that raising mice in the dark or treating them with an experimental cancer drug slowed tumor growth, suggesting a key role for controlling neuronal activity.
Scientists create synthetic melanin-like nanoparticles to overcome limitations of current dopamine delivery methods, achieving efficient and controlled release in the brain. The proposed method demonstrates promising results in reversing Parkinson's symptoms with high biocompatibility and non-toxicity.
Researchers have developed a more efficient and environmentally friendly method to produce hydrogen peroxide by using palladium-gold nanoparticles as a catalyst. The new process produces almost 100% hydrogen peroxide with minimal water formation, making it a promising alternative to traditional methods.
The coronavirus pandemic has led to significant changes in human health behavior worldwide. Experts in various fields discussed influencing factors and trends in the virtual panel discussion.
A University of Kentucky team will study the culprit behind thoracic aortic aneurysms with a $5.6 million grant from the NIH. The goal is to find new medical options to prevent surgical intervention.
A new analysis suggests that U.S. climate emissions from meat and dairy production are being understated due to undercounting of methane emissions. Methane emissions from North American livestock may be 39-90% higher than previously estimated, with potential consequences for global warming.
Researchers from Iowa State University discovered radiocarbon dates on rabbit and deer bones that suggest human occupation of the Coxcatlan Cave in Mexico may be up to 20,000 years older than previously thought. The findings could challenge the long-standing theory of human arrival in the Americas via the Bering Land Bridge.
Researchers developed an immunomodulatory approach using custom-made polymer microspheres to deliver magnesium ions directly into compromised bone. This accelerated bone regeneration rates by encouraging the immune system and skeletal system to work in tandem.
Researchers discovered that natural killer cells ramp up aerobic glycolysis about five days before T cells respond, shedding light on their role in mounting a rapid immune response. The findings have implications for using NK cells as immunotherapy in cancer treatment and cell therapy.
The West Virginia Clinical and Translational Science Institute Project ECHO program has been recognized as an ECHO Superhub, enabling outreach support to healthcare providers nationwide. With this designation, WVCTSI can offer training and expertise to establish new ECHO programs, reducing health disparities in underserved areas.
A study in fruit flies and rat models reveals that traumatic brain injury disrupts nuclear transport machinery, leading to protein build-up and neurodegenerative diseases. Researchers identify a key enzyme and molecule involved in the process, highlighting a potential target for new treatments.
Researchers aim to create a sustainable material design framework to mitigate pathogen exposure in drinking water. They will examine graphitic carbon nitride, a non-metal material with antimicrobial properties, to develop a cost-effective solution for treating drinking water.
A clinical trial found an implantable device is more than three times more effective in detecting atrial fibrillation in ischemic stroke patients. The device could prevent disabling strokes by almost 70% if detected early.
Scientists have discovered a climate pattern in the Arctic that drives co-occurrences of European heatwaves and large-scale wildfires with air pollution. The circum-Arctic wave (CAW) pattern is linked to exceptionally high PM2.5 levels and organic carbon aerosol concentrations.
A study found that exposure to negative news stories about science without context can damage public perceptions of trust and confidence in scientific work. The researchers tested the effects of different narratives on a large group of U.S. adults and found that those who read problem-focused stories were less likely to believe that sc...
Researchers at the University of Bath have discovered a new mechanism that enables magnetism and superconductivity to coexist in iron-based materials. The study found that RbEuFe4As4 exhibits both properties below -258°C, which could lead to breakthroughs in green energy technologies and next-generation computer hardware.
Researchers developed algorithms to solve curvature-dependent image processing problems using convex optimization, inspired by Euler's elastic curves and Gestalt laws of perception. The new models perform as well as current deep-learning algorithms but provide a deeper understanding of the structures learned.
A new study found that healthy lifestyles are associated with lower cognitive impairment risks in adults over 80, regardless of APOE ε4 status. The analysis confirmed that individuals with healthier lifestyles had a 55% and 28% lower risk of cognitive impairment compared to those with unhealthy lifestyles.
Researchers found that men are more likely to exhibit extreme behaviors in various areas, such as altruism, trust, fairness, and risk-taking. The study suggests that policies aimed at regulating these behaviors should be tailored towards men.
The Hi-CO technology provides high-resolution genome structural analyses combined with large-scale simulations, showing the arrangements of the genome's spool-like structures affect gene expression. Nucleosome folding influences the inner workings of genes, impacting accessibility of molecules to DNA.
Researchers at TUM have conducted comprehensive measurements of sea level rises in the Baltic Sea and North Sea with millimeter accuracy. The new method provides reliable forecasts on sea level trends, enabling planning of protective measures such as flood protection structures.
A new state-of-the-art method for controlling AI image generation has been developed by researchers at North Carolina State University. The approach allows users to retain certain characteristics across a series of images and manipulate specific elements while maintaining their identifiability. This technique has applications in fields...