Researchers at MD Anderson Cancer Center have discovered a novel triple immunotherapy combination targeting checkpoints in T cells and myeloid suppressor cells, improving anti-tumor responses and survival rates in preclinical models of pancreatic cancer. The study found that neutralizing specific immunosuppressive mechanisms dramatical...
APS patients often experience internal feelings of poor health despite normal lab values, with significant impairments in physical and cognitive function linked to lifestyle factors and mental health medications. Researchers are now working to better understand these impacts through systematic patient-reported outcomes measures.
Researchers used seafloor video and carbon dating to determine that an underwater landslide scar is too old to be associated with the 1918 earthquake and tsunami. Instead, they propose a rupture of a two-segment fault along the eastern wall of the Mona Rift as the source of the tsunami.
Research finds that black carbon aerosols from South Asia contribute to the melting of glaciers on the Tibetan Plateau, reducing precipitation and mass gain. The study reveals a 11% impact on average glacier mass loss in Tibet and 22% in the Himalayas since 2007.
Researchers have made a breakthrough in precision oncology for patients with metastatic urothelial carcinoma, identifying that certain cell surface molecules decrease or are absent in these patients, making them resistant to the new drug enfortumab vedotin.
Researchers discovered that ketamine increases background noise, impairing the function of thalamo-cortical neurons and affecting sensory perception. This finding may contribute to a better understanding of psychosis in schizophrenia.
Researchers developed intelligent programmable meta-imagers that generate learned illumination patterns to pre-select relevant details during measurement, improving high-accuracy sensing with reduced measurements. The system adapts to different types and levels of noise, outperforming conventional compressed sensing.
Researchers genetically engineered mitochondria to convert light energy into chemical energy, increasing ATP production and lifespan by 30-40%. The study provides new insights into mitochondrial function and offers a platform for studying age-related diseases.
Despite a significant increase in integrated plastic surgery residency positions, applications have remained unchanged. The number of applicants per available training slot decreased by about half, making it easier for accepted candidates to secure spots.