Researchers gathered vision data on hundreds of vertebrates and invertebrates, determining that land animals can see a wider range of colors. The study found that evolutionary history influences which colors a species sees, with invertebrates better suited to detecting short wavelengths of light.
Researchers successfully developed neutron-transmutation doping for 2D layered Indium Selenide (InSe) phototransistors, narrowing the bandgap and increasing electron mobility. The technique improved responsivity by about fifty times, opening up new opportunities in materials-based technologies.
Researchers found that a bridge therapy approach prior to consolidation therapy can improve event-free survival in patients with stable metastatic cancer after induction therapy. Patients who received this treatment had significantly better outcomes compared to those who underwent direct consolidation or post-induction therapy alone.
A study found epigenetic differences in airway cells of patients with asthma who have asthmatic mothers, suggesting impaired immune responses and potential new therapies for this subtype of asthma. The research was conducted in a diverse population and replicated in independent children's cells.
Scientists found that certain dynamical defects help explain the allowed vibrational modes inside amorphous solids, like glasses. These findings may lead to controlling the properties of amorphous materials.
Researchers at Purdue University have developed edible fluorescent silk tags with QR codes to verify whiskey authenticity, which can be activated with a smartphone scan. The technology has the potential to combat fake medications and address counterfeiting issues worldwide.
Researchers at Purdue University found that the presence of salt in seawater can impact a planet's habitability, with saltier oceans tending to result in warmer climates. This discovery may allow life beyond our solar system to exist further from its host star than previously thought.
A nationally representative study found that menthol cigarettes increase frequency of smoking among US youth, leading to higher nicotine dependence. The study suggests a strong case for the FDA's proposed ban on menthol flavoring in cigarettes to protect young smokers.
Researchers developed a simple physical model to explain DNA deformations caused by ions and temperature changes. The model reveals that salt-induced twist changes are driven by electrostatic interactions, while temperature-induced changes are related to DNA diameter variation. These findings provide new insights into the molecular mec...
A novel all-optical switching method has been developed to make optical computing and communication systems more power-efficient. The method utilizes the quantum optical phenomenon of Enhancement of Index of Refraction (EIR) to achieve ultrafast switching times, ultralow threshold control power, and high switching efficiency.
Researchers at MD Anderson Cancer Center found distinct gut microbiome signatures associated with immunotherapy response in patients with newly diagnosed glioblastoma. The study identified a link between gut microbiome signatures and immune checkpoint blockade response in melanoma, NSCLC, and sarcoma.
A new study by University of Chicago researchers found epigenetic differences in airway cells of patients with asthma who have asthmatic mothers, contributing to the development of severe asthma. The findings suggest that impaired immune responses may be an underlying cause of lack of therapeutic response to corticosteroids.
Researchers developed a fluorogenic probe that binds to the promoter region of influenza A virus RNA, creating a significant light-up response to identify its presence. This technique has shown promise for detecting influenza A more easily and may lead to the development of new antiviral drugs.
A new study finds that polar bears and brown bears have a complicated evolutionary history due to interbreeding. The analysis of modern bear genomes and ancient DNA from a 115,000-year-old tooth reveals gene flow from brown bears into polar bears, challenging previous hypotheses.
Scientists develop a method to suppress the crosstalk effect in top-emitting micro-LED-based displays by filling the space between each chip with a light-blocking matrix. The resulting full-color display prototype achieves a color gamut of up to 122% NTSC, surpassing conventional displays.
Researchers found that short-term cover crop use cannot reverse decades of soil microbial dynamics in response to unsustainable practices. Long-term fertilization disrupted nitrogen cycling communities, while cover crops enhanced biodiversity but had both positive and negative effects on soil microbes.
Archaeologists discovered a critical storage site for food and items in the Mugharat al-Kahf cave, revealing how inhabitants adapted to a mobile lifestyle after a significant aridification event. The findings provide new insights into non-funerary characteristics of communities during this period.
A new study found that patients with multiple myeloma who received a three-drug combination therapy had improved progression-free survival if they underwent an autologous stem cell transplant soon after treatment. The use of maintenance lenalidomide also conferred substantial clinical benefit.
A randomized study of temozolomide or temozolomide and capecitabine found the combination to be effective in treating advanced pancreatic neuroendocrine tumors, with a median overall survival of 53.8 months. Patients with MGMT deficiency showed greater odds of response.
The study found increases in screen time, alcohol use, and poor sleep among Australian girls during the pandemic. However, overall sleep improved, and some dietary choices improved during lockdown.
Researchers at Queensland University of Technology have developed a new method for controlling chemical reactions using intersecting light beams, paving the way for faster and more efficient 3D printing. This technology enables the simultaneous activation of multiple molecules, leading to the formation of solid materials.
A team from the Institute for X-ray Physics at the University of Göttingen has developed a new method for X-ray microscopy that uses imperfect lenses to achieve higher image quality and sharpness. The researchers used a lens consisting of finely structured layers deposited on a thin wire and adjusted it between the object to be imaged ...
A recent study published in the New England Journal of Medicine found that dostarlimab was effective in treating a subtype of rectal cancer, showing remarkable responses and resolving difficult symptoms. The treatment offers a more effective and less toxic alternative to traditional chemotherapy and radiation.
A new electrode design boosts carbon dioxide electroreduction, converting CO2 to CO with 54% efficiency and stable large current densities. The results demonstrate a promising approach for scalable CO2 abatement and renewable energy consumption.
A third dose of COVID-19 vaccine may be essential for kidney transplant patients in Japan to prevent severe disease and infection. Researchers found that only a third of patients developed sufficient antibodies after two doses, highlighting the need for additional protection.
Researchers at KAUST developed a new exhaust catalyst concept that can effectively remove NOx from vehicle emissions, resolving an ongoing debate over additive atoms in the catalyst mix. The team identified the ideal atomic recipe to catalytically remove NOx from diesel car tailpipes.
Research suggests that mothers-to-be on high-salt diets may increase their children's risk of developing hypertension and cardiovascular conditions. The study found that offspring exposed to a high-salt environment in utero had higher blood pressure and increased predisposition to hypertension, even after weaning.
Researchers at Yale University have discovered a potentially effective treatment for advanced pancreatic neuroendocrine tumors, with a combination of capecitabine and temozolomide yielding longer progression-free survival rates and higher response rates than temozolomide alone.
A new study reveals that red pandas are being driven closer to extinction due to human activities such as infrastructure projects and habitat fragmentation. The research suggests that minimizing human-induced disturbances is crucial for the survival of this species.
Babies born to mothers infected with COVID-19 show differences in motor function and relaxation, especially when held. Preliminary analysis suggests increased risk of neurodevelopmental changes compared to uninfected babies.
A nationwide study found a significant association between excessive BMI in late adolescence and the development of type 1 diabetes in young adulthood. The researchers analyzed data from over 1.4 million adolescents and found that those with obesity had double the risk of developing type 1 diabetes compared to those with optimal BMI.
A pregnant woman battled COVID-19 for 22 days before receiving life-saving ECMO treatment. After a successful delivery of a healthy baby boy via emergency C-section, the mother made a full recovery with extensive physiotherapy.
A Phase II study found that immunotherapy before surgery improved median progression-free survival and overall survival for undifferentiated pleomorphic sarcoma and recurrent dedifferentiated liposarcoma patients. The treatment also showed an association between intratumoral B-cell receptor repertoire and survival.
A new study found that circulating tumor DNA can identify stage II colon cancer patients who benefit from chemotherapy, sparing others the need for treatment. The study showed reduced use of chemotherapy without compromising survival rates.
A review at the Euroanaesthesia congress recommends that doctors and nurses take 20-minute power naps during night shifts to improve staff and patient safety. This is due to the risks of fatigue-induced accidents, decreased cognitive function, and impaired teamwork, which can lead to poor patient care.
A Phase 3 clinical trial is investigating the effectiveness of a combination of two immunotherapy drugs, nemvaluekin alfa and pembrolizumab, compared to standard chemotherapy for patients with platinum-resistant ovarian cancer. The trial aims to provide a novel treatment option with better efficacy and safety profiles.
Researchers designed artificial peptides that can bind to viral proteins, blocking entry into cells and causing viruses to clump together. These 'miniproteins' were found to be thermostable and safe for use in humans, with promising results in lab tests and animal models.
A customized WeightWatchers program has been shown to effectively manage Type 2 diabetes by lowering blood glucose levels and promoting significant weight loss. Participants in the six-month clinical trial experienced improved glycemic control and overall well-being, with clinically meaningful and statistically significant results.
A German study has found a link between long-term exposure to air pollution and the severity of COVID-19 disease. The research, presented at the Euroanaesthesia Congress in Milan, Italy, found that counties with higher levels of nitrogen dioxide had more ICU beds occupied and mechanical ventilation needed for COVID-19 patients.
The UK Maternal Mortality Reports show that heart disease remains the leading cause of death among women during pregnancy, followed by epilepsy and stroke. Anaesthetists are working to improve outcomes through better risk assessment, anti-clotting medication, and multidisciplinary training.
Researchers found that mouth-to-mouth ventilation while wearing a face mask is effective in reducing the risk of COVID-19 transmission. The study used a breathable face mask and found that over 90% of breaths into the mouth were judged effective.
A study by Kobe University researchers found significant socio-economic disparities in physical activity during the COVID-19 pandemic, with vulnerable populations experiencing reduced levels of activity. The findings highlight the need for continuous monitoring to address widening health disparities stemming from economic circumstances.
A combination of ramucirumab and pembrolizumab reduced the risk of death by 31% compared to standard care in advanced non-small cell lung cancer patients who had previously failed immunotherapy. The study found that these patients lived significantly longer, with a mean overall survival time of 14.6 months.
A recent study found that local DNA motion remains steady throughout interphase, allowing cells to conduct routine tasks like RNA transcription and DNA replication under similar nuclear environments. This steady-state motion provides a robust cellular system, unaffected by various nuclear changes.
A study by researchers at the University of Oldenburg found that spider webs are contaminated with varying levels of microplastic particles, including PET and PVC. The team discovered that the amount of plastic particles in the webs depends on location, with roads having high traffic volumes producing more microplastics.
Researchers at Massachusetts General Hospital discovered a novel immunotherapy mechanism that uses CD4+ T helper 2 cells to suppress breast cancer development. These cells force breast cancer cells to revert to benign breast gland cells, providing new insights into the treatment of this disease.
A Mayo Clinic study found that disparities in opioid treatment access persist among women, Black and Hispanic populations. Despite increased access, these groups continue to face systemic barriers, including racism, mistrust of healthcare professionals, and lack of clinicians able to prescribe buprenorphine.
Researchers at Tokyo Institute of Technology developed a computational DNA droplet that can recognize specific combinations of chemically synthesized microRNAs as biomarkers of tumors. The droplet can perform logic computing operations and detect multiple cancer biomarkers simultaneously.
A new drug combination of ramucirumab and pembrolizumab significantly extended overall survival in advanced non-small cell lung cancer patients who had progressed on prior immunotherapy. The study found a 31% reduction in risk of death compared to standard therapy, with median overall survival times of 14.5 months.
Researchers developed a wood-based insulating material that offers superior thermal performance to existing plastic-based materials. The new aerogel-integrated wood material is created without adding additional substances and has the potential to replace fossil-based aerogels for energy efficiency and sustainable development.
The study found that combination chemoimmunotherapy with ibrutinib improved progression-free survival over standard chemoimmunotherapy in patients with previously untreated mantle cell lymphoma. The median PFS was 80.6 months with the ibrutinib combination versus 52.9 months in the control arm.
From 2004 to 2020, there was a notable increase in actions taken against physician licenses due to substance use and psychological or physical impairment. The study found that these issues were affecting the medical community, emphasizing the need for improved support systems and policies.
A team of researchers from Rice University has modeled the dynamics of grain boundaries in polycrystalline materials using a rotating magnetic field technique. The study shows that grain boundaries can change readily in response to shear stress, and voids in these structures can act as sources and sinks for their movement.
Researchers analyzed 140 complete autopsies of COVID-19 patients and found the most frequent profile is men aged 60-77 with acute lung injury, often accompanied by vascular disease, heart disease, and diabetes. This profile was associated with a shorter time to death.
A new data-driven model, SOURCE, tracks the opioid crisis over 21 years to better understand its evolving nature and guide policy response. The model projects that deaths from opioid overdose will increase before trending downward as opioid use disorder decreases.
A recent study of 7,600 adults found that higher levels of light- and moderate-to-vigorous intensity physical activity were associated with a reduced risk of stroke. Conversely, greater sedentary time was linked to an increased risk of stroke.
Researchers argue that the Glasgow Leaders' Declaration on Forests and Land Use is too vague regarding gross vs net deforestation. This distinction matters for carbon dioxide emissions. Stopping gross deforestation would significantly reduce emissions.
Researchers found that plesiosaurs used a unique swimming motion, twisting their flippers to create lift and propel themselves through the water. This was achieved by using muscles to twist the flippers around their long axis, allowing for efficient swimming without rotating the upper arm and thigh.
A new study by Carnegie Mellon University analyzed the impact of the COVID-19 pandemic and George Floyd's murder on crime rates in 28 US cities. The study found that homicides and auto thefts increased, while robberies and larcenies declined. The authors suggest that social unrest, economic conditions, and changed police behavior may b...
A 58-year-old woman from Armenia suffered from severe finger pain for over 40 years when knitting, which was later revealed to be caused by a rare benign glomus tumor under her fingernail. The tumor was successfully removed in a 30-minute operation, restoring the patient's quality of life and allowing her to return to her hobby.