New research reveals that expanded alternative licensure pathways can lead to attenuated pay for new elementary school teachers. The study found that districts hiring more than 50% of their new teachers through alternative routes experienced stagnating teacher pay after policy implementation.
Researchers propose a new method of clustering colorectal cancer patients using differential presence of exons (DPE) sequencing, which can provide valuable information on CRC progression and response to therapy. This analysis may also reduce costs and time required for staging CRC patients.
Researchers at Mayo Clinic Arizona have developed a new intravesical chemotherapy delivery system called TAR-200, which is safe and shows initial evidence of effectiveness in treating muscle-invasive bladder cancer (MIBC) in frail patients. The treatment has been shown to limit cancer growth while minimizing toxic effects.
A Rutgers study found that nearly one in five LGBTQ people experienced an increase in intimate partner violence after the COVID-19 pandemic began. Those living in the southern US were more likely to report this increase, with intimate partner violence also linked to greater depressive symptoms.
A national-level analysis found substantial adverse maternal outcomes among pregnant patients with COVID-19 infection during the early pandemic period. The study highlights increased odds of severe respiratory complications among these patients at delivery.
Researchers at Binghamton University and Brookhaven Lab used advanced spectroscopy techniques to study the effects of peroxides on copper oxide surfaces. They found that peroxides significantly enhanced CuO reducibility in favor of H2 oxidation, while acting as an inhibitor to suppress CO oxidation.
Researchers at Johns Hopkins University discovered how histone H3 controls cell specialization in worms, offering insights into cell differentiation and potential links to diseases. The study used CRISPR gene-editing technique to track the role of histones in development.
Researchers created the integrated-gut-liver-on-a-chip platform to examine how gut and liver cells interact, particularly in relation to non-alcoholic fatty liver disease. The study showed significant changes in gene expression and DNA damage when free fatty acids were introduced, leading to cell death similar to severe cases of NAFLD.
The labor force participation rate for people with disabilities increased to a record 40.2% in March 2023, surpassing the rate for those without disabilities (77.6%). This growth reflects an ongoing recovery from the COVID-19 pandemic and may be driven by factors such as increased job opportunities and family needs.
Researchers have found that a strong electric field can create hydroxide, which reacts with pollutants and greenhouse gases, altering our understanding of atmospheric chemistry. This new mechanism changes how scientists build computer models to forecast air pollution.
Researchers developed an ASO treatment that improves bile duct development and prevents fibrosis and cell death in animal models of Alagille syndrome. The study offers a potential therapeutic option for patients with this condition, potentially bypassing the need for liver transplant.
A randomized controlled trial of High School FLASH, an LGBTQIA+ inclusive evidence-based sex education curriculum, found that the program reduced homophobic and transphobic beliefs among both LGBTQ and straight/cisgender students. The study also showed improved feelings of safety and connection to peers among LGBTQ students.
Researchers compared woolly mammoth genomes with modern-day elephants to find unique traits. They identified genes responsible for small ears, fat metabolism, and cold perception, which became more defined over time.
A study led by Dr.Ningli Wang and Dr.Yuan Xie found that retinal microvasculature alterations can predict acute mountain sickness (AMS). The researchers used optical coherence tomography angiography to measure retinal capillary blood flow density, revealing increased perfusion pressure as a key mechanism in AMS pathogenesis.
Researchers at Trinity College Dublin have discovered a new process that explains why cells have unique identities. By studying Polycomb protein complexes, the team found that different forms of these proteins recruit distinct complexes to DNA, shedding light on cellular identity and its potential impact on cancer treatments.
A new study calls for internet access to be declared a basic human right to address socio-economic disparities. In developing countries, internet access can determine education, healthcare, housing, and employment outcomes. The study advocates for free internet access and digital skills training to ensure equal opportunities.
A team led by Prof. ZHANG Kaiming solved six conformations in the second-step self-splicing of Tetrahymena ribozyme, revealing its mechanism on an atomic level. The researchers used cryo-EM to resolve RNA structures, providing insights into the advantages of this technique for studying heterogeneous molecules.
A new study reveals that targeting the SWI/SNF protein complex can disrupt PU-1-directed enhancer programs in AML cells, leading to therapeutic responses and rapid tumor regression. The findings also show that these inhibitors have manageable side effects on normal blood cells.
Researchers find that changes in wind patterns caused by warmer tropical waters are steering storms closer to the US East and Gulf coasts, increasing risk for residents. The study reveals that this phenomenon is linked to stronger hurricane frequency due to climate change.
A comprehensive review of e-nose methods and algorithms aims to improve smell detection capabilities. The study highlights limitations of current gas sensors and provides an outlook on algorithm design.
A new study reveals a steady decline in native leaf-litter ants and simultaneous increase in nonnative ants in Florida, even in protected natural areas. Nonnative ants are most likely arriving with goods transported to the state from around the world.
A Dartmouth College study found that more than 500 home runs since 2010 can be attributed to higher-than-average temperatures due to climate change. Rising temperatures could account for 10% or more of home runs by 2100, with some stadiums experiencing significant spikes in home run totals.
Researchers at Argonne National Laboratory and University of Chicago developed a hybrid simulation process using IBM quantum computers to solve electronic structure problems. The new method uses classical processing to mitigate noise generated by the quantum computer, paving the way for future improvements.
A new research approach suggests integrating biodiversity auditing into conservation plans to effectively support a wider range of important species. This method has been successfully tested in the UK's East Anglia region and could benefit biodiversity nationally, including the European Union's 2030 Biodiversity Strategy.
A recent study led by Children's Hospital of Philadelphia identifies two different regulatory T cell populations, one related to autoimmunity and the other to protective immunity. The findings could pave the way for new treatments that target the immune system selectively.
The Princeton-led team measured the dark matter's 'clumpiness,' finding a value of 0.776 that conflicts with the Cosmic Microwave Background's value of 0.83. The discrepancy suggests the standard model might be incomplete or has an error, prompting further investigation.
Research from Amsterdam UMC reveals that all prominent migrant groups are suffering more from long-covid than the native Dutch population, with rates ranging from 26-50% higher. The study highlights the need for awareness and accessible healthcare services in ethnic minority and migrant communities.
A UC Riverside-led study found that reduced PTPN2 activity in intestinal epithelial cells leads to decreased Paneth cell antimicrobial peptide production, disrupting the gut microbiota and increasing E. coli. This loss can serve as a marker of IBD disease.
A team of scientists at MUSC identified a key gene that plays a role in the link between long-term stress and a common type of depressive behavior in mice. The study suggests that there may not be one central mechanism by which stress causes depression, but rather multiple pathways connecting stress with different symptoms.
A new UC Davis study found that high blood pressure in young adulthood is associated with lower regional brain volumes and worse white matter integrity, both factors linked to dementia. The research also showed sex differences in the negative brain changes, with men exhibiting stronger effects than women.
A randomized clinical trial found that anakinra did not prevent mechanical ventilation or reduce mortality risk in hospitalized patients with severe COVID-19 pneumonia. Future research is needed to assess anakinra in less severe cases.
Psychiatrists at Indiana University School of Medicine found deaths by suicide increased during the week of a full moon, especially in people over age 55. They also identified 3-4 p.m. and September as peak times for suicides.
A new equation and 3D imaging technology have been developed to score pancreatic cancer patients for surgical removal of their tumor. The method provides a precise way to determine which patients are eligible for surgery, with the potential to improve treatment outcomes.
A team at the University of Pittsburgh has created a framework to analyze the influence of online conspiratorial content on individuals and communities. The project aims to identify sociodemographic and psychometric factors that contribute to the spread of such messages.
A new study from Weill Cornell Medicine has identified four clinically distinct groups of people with autism spectrum disorder, each with unique brain connection patterns and behavioral traits. The findings highlight the potential for personalized therapies tailored to individual subgroups, which may lead to more effective treatments.
A new UCLA study identifies sex-specific brain signatures associated with obesity in men and women, revealing differences in brain networks related to early life adversity, mental health, and sensory stimulation. The findings suggest the need for tailored interventions based on an individual's sex.
A recent study has found that the fungus Candida auris uses a genetic agent called the Hil family to adhere to host tissue and form biofilms, making it difficult for humans to fight off infections. This adaptation allows the fungus to evade the human immune system and become resistant to anti-fungal drugs.
African provinces' inclusive wealth per capita rose modestly by 1% between 2012 and 2018, signaling weak sustainability performance. The study highlights the tradeoffs between income and natural capital growth, emphasizing the importance of harmonizing national and subnational interventions.
A German-Chinese research team has developed a general method to produce two-dimensional nanoparticles, which have high catalytic potential. The synthesis process is carried out in a simple aqueous solution without toxic additives or high temperatures.
A survey of science journalists in Latin America and the Caribbean reveals key ethical priorities, protections, and violations. The report aims to establish guiding principles for science journalism globally.
A population-based study found that pregnancy-associated cancers have a higher overall 5-year mortality rate compared to non-pregnancy associated cancers. The study highlights the need for improved cancer screening and treatment options during pregnancy.
A new type of meta-optics, developed at Harvard, has been successfully tested at Graz University of Technology, allowing the observation of ultra-fast physical processes. The lens uses extreme ultraviolet radiation to track charge carriers in space and time, enabling optimization of modern transistors and optoelectronic circuits.
A team of investigators created embryo-like structures from monkey embryonic stem cells and transferred them into female monkeys, which implanted and elicited a hormonal response similar to pregnancy. The study provides new tools and perspectives for exploring primate embryos and reproductive medical health.
Researchers from George Mason University found that anti-tobacco campaigns on Facebook discussing the risks of second-hand smoking to pets received the most user engagement. The studies analyzed factors influencing effective antismoking campaigns and user interaction.
A clinical study has shown that vaccination during pregnancy can effectively prevent severe respiratory syncytial virus (RSV) disease in infants. The vaccine was found to be well-tolerated and provided over 80% protection against RSV illness, with benefits expected for vulnerable populations worldwide.
A recent study by England Hockey star Tess Howard found that 70% of teenage girls in the UK dropped out of sports due to body image concerns related to their clothing. The research led to the introduction of new, more inclusive uniform policies allowing athletes to choose between skirts and shorts.
Regular third trimester ultrasound scans can help identify undiagnosed breech pregnancies, allowing for better care before and during labor. This could lead to improved perinatal outcomes and reduced rates of undetected breech pregnancy by 71%.
Residual carbon emissions are a major obstacle to achieving net-zero greenhouse gas emissions by 2050. According to University at Buffalo researcher Holly Jean Buck, the world must reach net-zero this century to limit temperature increase, but residual emissions pose significant challenges.
A toolkit for coral gardening could accelerate reef recovery in Saudi Arabia and globally. The Maritechture TM system includes tiles, stackable crates, and coral pods to create artificial reefs that attract natural coral settlement.
Users appreciate automation's ability to learn personal preferences, reducing tedious tasks. However, they also desire user control and consent for system engagement, leading to a delicate balance of interactivity and automation.
Researchers from Chinese Academy of Sciences have doubled lithium storage capacity in hard carbon anodes by exploring lithiation boundary parameters. The study reveals the dual effect of lithium intercalation and reversible lithium film as key to high-reversible capacities.
A new study published in the New England Journal of Medicine found that doxycycline can reduce the incidence of syphilis, gonorrhea, and chlamydia by two-thirds when taken within 72 hours after condomless sex. The research also highlighted a slight increase in antibacterial resistance, emphasizing the need for further exploration.
A team of scientists from City University of Hong Kong and HKUST discovered novel, tridimensional compounds with high anticancer activity and low toxicity. These compounds can overcome drug resistance in cancer cells by inducing a different cell death pathway.
A study by Beth Israel Deaconess Medical Center found that climate change-related natural disasters have increased since 1980 and cost the US over $2 trillion in recovery costs. The analysis suggests that rising CO2 levels and temperatures will lead to more frequent and severe disasters, with exponentially increasing costs.
A new reputation-based consensus mechanism is proposed to improve blockchain node deployment on vehicles and RSUs, reducing block propagation time and increasing efficiency. The proposed mechanism is verified through simulation results in a 12km×12km square region.
A blood draw can provide valuable information on the effectiveness of peptide receptor radionuclide therapy for neuroendocrine cancer patients. Blood-based biomarkers PPQ and NETest were found to predict PRRT response with 96% and 90% accuracy, respectively. The study opens possibilities for tailoring treatment to individual patients.
A team of Cornell University scientists has dusted off an ancient electrochemical equation to better understand the conversion of carbon dioxide. The Cottrell equation enables researchers to control experimental parameters and produce useful carbon products like ethylene, ethane, or ethanol.
A study from the University of East Anglia found that environmental impact assessments often fail to account for species movement between sites, leading to underestimated impacts on wildlife. The research highlights a planned airport development in Portugal that could affect over 10 times the number of Black-tailed Godwits estimated by...
Researchers found that even low levels of glyphosate herbicide residues harm endophytic microbes in garden strawberry, which promote plant nutrition, disease resistance, and stress tolerance.
Researchers replaced reactive hydrogens in PHA plastics with methyl groups, enhancing thermal and mechanical properties. This approach enables closed-loop chemical recyclability, a crucial step towards increasing sustainable use of PHAs.