Researchers developed guidelines to enhance accuracy of spike-in normalization, a widely-used molecular biology technique. The study highlights common pitfalls and provides recommendations for improving results.
A phenomenological study explores the lived experiences of autistic adults misdiagnosed with BPD, highlighting challenges in distinguishing between autism and BPD. Participants reported harmful treatments and stigma, but found validation and improved mental health after receiving an autism diagnosis.
The UK's first menopause education and support programme, InTune, will trial two new courses to help individuals before and during the menopause. The Be Prepared for Menopause course covers what menopause is, symptoms, diagnosis, and management, while the Perimenopause Programme provides peer support and education for those experiencin...
Researchers from Okayama University successfully controlled the population of the thorium-229 isomeric state using X-rays, a crucial step towards building a compact and portable nuclear clock. This achievement demonstrates the potential for nuclear clocks to advance fundamental physics research and other applications such as GPS systems.
Scientists have developed a comprehensive evaluation of spatiotemporal fusion techniques for monitoring eutrophic lakes. By addressing processing and modeling errors, they can generate high-resolution data on chlorophyll-a concentration, providing guidelines for future studies.
A novel mullite anti-gyroid/SiC gyroid composites are fabricated through DLP 3D printing, demonstrating significant improvement in mechanical properties and EMW absorption. The metastructure's gyroid structure design enables tunable EMW absorption and impedance matching.
A pioneering method for soil moisture retrieval using satellite navigation systems has been introduced, significantly boosting the accuracy and efficiency of global data collection. This research tackles the challenges posed by geographical disparities in soil moisture assessment.
The Tibetan Plateau plays a crucial role in atmospheric synergy between westerly and Asian monsoon systems. Research efforts, such as the Second Tibetan Plateau Scientific and Research program, have improved understanding of water vapor changes and land–atmosphere interactions.
Scientists at Brigham and Women's Hospital have created a strategy to boost mitochondrial activity in T cells, improving their ability to penetrate and kill tumor cells. The new approach helps to overcome a major barrier in immunotherapy by increasing the energy capacity of T cells.
Researchers found that high-pressure homogenization enhances paprika oleoresin solubility and stability, allowing for greener and safer use in food products. The technique also broadens the potential uses of natural colorants and nutrients.
Researchers have developed a lithium-sulfur battery with improved iron sulfide cathode, retaining capacity over 300 charge-discharge cycles. The battery also withstands physical stress, including folding or cutting, making it safer and more efficient.
A new study published by UNM Department of Psychology Assistant Professor Jeremy Hogeveen and colleagues found that adolescents who experienced a mild traumatic brain injury (TBI) showed no significant increase in depression compared to those without a history of TBI. The study, using data from the Adolescent Brain Cognitive Developmen...
A study published in Brain Communications found that heatwaves can trigger more seizures in individuals with severe epilepsy. Researchers used intracranial electroencephalography to track brain activity during heatwaves and non-heatwave periods, revealing a significant increase in seizure frequency during hot weather.
A novel catalyst Au/BiOx-TiO2 enhances oxidative methane coupling by activating C-H bonds and preventing overoxidation, yielding 97% selectivity for C2+ products. The photocatalyst demonstrates stable performance up to 50 hours and outperforms previous catalysts.
Researchers found that regrowing tropical forests on pastureland can reduce soil carbon emissions by nearly two-fold, offering a quick win in the fight against climate change. This unexpected finding is attributed to warmer temperatures experienced by soils in pastureland, which may explain higher carbon dioxide emissions.
Researchers at Tohoku University developed a new electrocatalyst by doping cobalt oxide with erbium, achieving high oxygen evolution performance and stability in acidic conditions. The Er-doped Co3O4 catalyst surpassed the performance of many precious metal-free catalysts.
New research finds that employees who feel pressure to work while sick experience deviant behaviors like theft and mistreatment of coworkers. The cost of such behavior, known as 'presenteeism,' can be staggering, with annual losses estimated at up to $150 billion.
The RESILIENCE clinical trial explores the effectiveness of remote ischemic conditioning to prevent cardiotoxicity in lymphoma patients undergoing anthracycline-based chemotherapy. The trial aims to reduce heart failure prevalence and improve quality of life for cancer survivors.
A team of UBC Okanagan researchers has created a new mechanical heart valve that combines the strengths of both mechanical and tissue replacement technologies, offering improved performance and durability.
A new dynamic anti-counterfeiting application has been developed based on fluorescent electrophoretic display technology. The device exhibits multifunctional anti-counterfeiting capabilities with a fast response time, high contrast ratio, and bright green fluorescence.
Researchers used mathematical modeling to calculate the likelihood of successfully scheduling a meeting based on several factors. As the number of participants grows, the probability of scheduling a successful meeting decreases sharply, with a critical point where the likelihood drops significantly.
A new study reveals that plant-derived SOAs can activate defences in nearby plants, persisting even after oxidation. The elemental composition and quantity of SOAs determine their biological functions, allowing plants to tailor their defenses based on different types of chemical cues.
The study evaluated 7 guidelines for the diagnosis and treatment of HEV infection, finding significant variability in quality and consistency. The guidelines scored poorly in areas such as stakeholder involvement, rigor of development, and applicability, highlighting the need for improvements.
A Cleveland Clinic study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide. The study found that medication's active agent, dosage, treatment indication, and persistence with the medication were associated with weight change.
A new study examines the relationship between the 2024 M7.6 Noto Hanto earthquake and a preceding earthquake swarm in Japan's Noto Peninsula. The research highlights the importance of monitoring seismic swarms and understanding fluid migration patterns to enhance predictive models for future seismic events.
The study reveals significant spatial differences in diversity, structure, and function of microbial communities in the rhizosphere of Boehmeria nivea L. Volcanic soil plays a key role in forming microbial community diversity. Bacterial generalist species dominate, while fungi show greater ability to break down complex organic polymers.
Rice University researchers developed ElasticDiffusion, a method that separates local and global signals to create non-square aspect ratio images without visual imperfections. The new approach can improve consistency and realism in AI-generated images, but still requires significant computational power.
Researchers at ETH Zurich have developed a new method to degrade perfluorooctane sulfonates (PFOS), a subgroup of forever chemicals. Using piezocatalysis, the team was able to break down 90.5% of PFOS molecules in water samples, offering a potential solution to environmental pollution.
Researchers have developed a lab-made pouch battery using scaled-up polymer at an approximate cost of $20 / kg, achieving a capacity of nearly 70 mAh g’ and a middle discharge voltage of 1.4 V. This breakthrough paves the way for producing low-cost alternatives to lithium-ion batteries.
A new study from Aarhus University has developed a method to extract more information from fingerprints, improving forensic analysis. The technique uses chemical imaging and can separate overlapping fingerprints and enhance faint ones.
The number and scope of forest ecology/forestry research are expanding, with a shift towards more applied topics and the use of advanced statistical tools. Publications in eight ecology journals increased from 820 in 2010 to 2,354 in 2021.
Researchers found that neoself-antigens, presented on MHC-II, induce an immune response and lead to autoimmunity in lupus patients. EBV reactivation increases the presentation of these antigens, triggering T cell activation and autoimmune disease development.
Researchers tested tivozanib with nivolumab in patients with advanced clear cell renal cell carcinoma and found no benefit from combining the two treatments. Repeat ICI therapy should be discouraged due to lack of improvement in overall survival or response rates.
The development of vaccine adjuvants has evolved significantly, shifting from empirical methods to a more structured approach grounded in rational drug design. This new era emphasizes the importance of understanding structural and functional traits of adjuvants.
The Einstein-led PROVIDENT consortium will conduct four projects to develop countermeasures against a wide range of emerging viruses, with a focus on three virus families: nairoviruses, hantaviruses, and paramyxoviruses. The grant aims to quickly respond to emerging viruses with existing research and tools.
Hassan's research focuses on creating advanced techniques for collecting and integrating data provenance to enhance threat detection. The project also includes educational initiatives to prepare the next generation of cybersecurity professionals.
A new ERC grant will support research into the dietary practices of ancient people, revealing their identities and social connections. The study will analyze biomolecular samples from at least 150 ancient burials, combining methods to identify relations and uncover nuanced dietary data.
A study from Ann & Robert H. Lurie Children's Hospital of Chicago found that nearly 80% of transgender and gender diverse youth screened positive for suicide risk, with one out of four having active suicidal thoughts. The study highlights the importance of universal suicide screening for all youth, regardless of reason for seeking care.
A team of researchers from China successfully created plant-based simulated yellow croaker meat tissues using dual-nozzle 3D printing. The study found that the texture characteristics, moisture distribution, and nutrient content of the simulated fish were close to those of real fish, with a printing accuracy of over 90%.
Children with asthma exposed to high levels of indoor allergens are at increased risk of developing respiratory viral infections. The study found that these allergens contribute to more severe pulmonary outcomes, including reduced lung function and increased inflammation.
Genethon has developed an innovative gene therapy vector that effectively targets muscle tissue while reducing the risk of liver penetration. The new capsid design uses AI predictive methodology to improve efficacy and safety, paving the way for more effective treatments for neuromuscular diseases.
The UAB researchers propose a multilayer structure of DNA that is fully compatible with the structural and functional properties of chromosomes. This organization can be explained by weak interactions between nucleosomes, which are repetitive blocks that fold the DNA double helix.
A new report by the Earth Commission warns that inequalities and overconsumption of finite resources are key drivers of the shrinking 'Safe and Just Space', which is expected to collapse unless urgent transformations take place. The paper calls for changes in economy, resource management, and investment in sustainable technologies to r...
Research reveals that crude oil pollution dramatically reduces sea otter fur buoyancy, placing newborn pups at risk due to their larger surface area relative to body mass. After cleaning, the buoyancy of the fur improves but not fully recovers, highlighting the need for thorough detergent rinsing.
A new species, Senecio squalidus, emerged in the UK after crossbreeding of two plants native to Mount Etna. Genetic analysis shows a rapid reorganization of its genome, driving its unique survival in challenging environments.
A landslide in remote Greenland caused a mega-tsunami that sloshed back and forth across a fjord for nine days, generating vibrations throughout the Earth. The study used mathematical models to recreate the event and demonstrate how the sloshing of water would have continued, matching global seismic recordings.
Researchers found that coastal dams can either increase or decrease flood risks, depending on the duration of a surge event and friction from water flow. The study, published in the Journal of Geophysical Research: Oceans, analyzed data from Charleston Harbor and other estuaries to make this surprising discovery.
A groundbreaking study has provided novel insights into the molecular underpinnings of gastric cancer peritoneal spread, paving the way for more effective treatments. The research also demonstrated the safety and potential efficacy of a new treatment approach in a clinical trial.
A newly discovered ancient primitive Devonian coelacanth fish, Ngamugawi wirngarri, has provided significant insights into the early anatomy of this lineage that eventually led to humans. The fossil, dating from the Devonian Period, reveals that tectonic plate activity had a profound influence on rates of coelacanth evolution.
A nationwide study found that over 840,000 new residential properties were built in floodplains across the US, with about 398,000 in Florida. Despite this, many communities have taken proactive measures to limit floodplain development through smart regulations and practices.
The new Corporate Lab aims to advance collaboration between industry and public sector researchers to address real-world challenges in sustainable living and digital technologies. It will develop and trial novel digital technologies prioritizing sustainable ecosystems and lifestyles, including energy-efficient AI algorithms, green clou...
A new study from the University of California Rady School of Management finds that most US states with food waste bans have seen little to no reduction in landfill waste, except for Massachusetts. Researchers highlight three key features of Massachusetts' law as effective in reducing waste.
Researchers analyzed ancient human bones to assess puberty stages in 13 Ice Age teens, ages 10-20. Most entered puberty at 13.5 and reached adulthood between 17-22 years old.
Researchers have developed a new diagnostic algorithm using positron emission tomography (PET) to distinguish between Alzheimer's disease and primary tauopathy. The biomarkers enable doctors to identify the presence of a 4-repeat tauopathy with high accuracy, facilitating earlier diagnosis and personalized treatment strategies.
Repeated antibiotic use can cause defects in the gut's protective mucus barrier, even months after treatment. This is due to changes in the microbiota or direct effects of antibiotics on the mucus layer. The findings suggest that antibiotics should be used responsibly to prevent long-lasting damage.
Associate Professor Justine Tigno-Aranjuez received a $1 million NSF CAREER Award to study the impact of the NOD2 pathway on inflammation. Her research aims to understand how lipid mediators are produced and how they influence inflammation.
USC Keck School of Medicine has received a $12.5 million gift from Jerre Stead to support neurological surgery innovation and entrepreneurship. Dr. Aaron Cohen-Gadol, a renowned neurosurgeon, has joined the faculty, bringing his education and innovation platform, Neurosurgical Atlas.
Researchers found that biological condensates, previously overlooked cellular structures, play a significant role in modulating cell activity and influencing global traits such as antibiotic resistance. These 'blobs' can separate or trap proteins and molecules, affecting cellular behavior and electrochemical processes.
Climate change exacerbates agricultural environmental harm, requiring sustainable practices to stabilize global food supply. Researchers identify new methods like precision farming and crop rotation to reduce greenhouse gas emissions and prevent feedback loops.
The researchers used noncontact atomic force microscopy to analyze the surface structure and found that the surface rearranges to allow aluminum atoms to penetrate into the material. This rearrangement reduces energy and stabilizes the structure without changing its composition.