An AI-based imaging tool predicts reduced coronary blood flow, measured with CT-derived fractional flow reserve (FFR-CT), to diagnose angina and predict future cardiovascular events. The study shows that FFR-CT adds incremental value to traditional cardiovascular risk factors in predicting cardiovascular outcomes.
Daily scans taken during prostate cancer radiotherapy can identify changes linked to future rectal bleeding as early as one week into treatment. This allows doctors to adapt radiotherapy to limit side effects while maintaining cancer control.
A team of researchers has reconstructed how the cerebellum establishes its connections with the rest of the brain during earliest stages of life. The work describes the phases in which these neural connections emerge, expand, and are refined, offering a comprehensive map of cerebellar projections across the mouse brain.
A study found that a global pandemic is quietly wiping out sea urchins around the world, with populations nearing local extinction in the Canary Islands. The 2022-2023 mass mortality event affected the entire population of the species across the archipelago, causing a 74% decrease in La Palma and a 99.7% decrease in Tenerife.
A study has uncovered a promising three-lncRNA signature that could improve early diagnosis and treatment strategies for non-metastatic hepatocellular carcinoma. The lncRNAs HEIH, MIAT, and HOTAIR were found to be significantly elevated in cancerous tissues.
Researchers develop a cohesive framework for designing high-performance flexible vdW electronic and optoelectronic systems, exploiting strain engineering to tune physical properties. The approach enables devices with improved mobility, sensitivity, and functionality, including sensing, memory, and computation capabilities.
Researchers at Tohoku University and Indian Institute of Technology Indore developed a Cu14 nanocluster with a single exposed Cu site, exhibiting high ammonia selectivity and production rate. The findings support the creation of efficient metal nanocluster catalysts for green energy production.
Researchers discovered high concentrations of Benzothiazoles in outdoor airport PM10, indicating significant input from airport activities. The findings suggest specific chemical markers for tracing airport non-exhaust emissions into the air.
Researchers found that nanoplastics entered the bloodstream and accumulated in organs within days of ingestion, potentially leading to disorders in nervous and reproductive systems. The particles were primarily expelled through the intestine, but some remained trapped for a long time.
A study of over 10,000 women aged 65 and older found that moderate tea consumption was associated with higher bone mineral density, a key indicator of osteoporosis risk. In contrast, excessive coffee consumption, particularly in those who drink alcohol, may be detrimental to bone health.
Researchers found that adding formic acid to traditional UV-based oxidation systems boosts PFOA defluorination rates from 27% to 89%, leveraging reductive radicals for efficient degradation. Acidic conditions and oxygen-free environments enhance performance.
A new Cochrane review found that free or subsidized school meals slightly improve math achievement and enrolment rates in low- and middle-income countries. School feeding programs also likely contribute to small gains in physical growth indicators, but evidence from high-income countries is limited.
Researchers at the National Institute for Fusion Science used high-precision diagnostic instruments to measure temperature, turbulence, and heat propagation in a plasma. The experiments revealed two types of turbulence: a mediator-type that connects distant regions quickly, and another type that carries heat outward more slowly.
A landmark UK study reveals that around £13 million is spent annually on hospital admissions and post-discharge care for acute heavy menstrual bleeding. The study suggests that many cases can be managed in the community or by outpatient services, reducing the need for expensive hospital admissions.
Teenagers who struggle with their bodies are at risk of developing eating disorders and depression in early adulthood, according to a new study. The research, which followed over 2,000 twins, found that body dissatisfaction at age 16 predicted greater symptoms of mental health issues well into the twenties.
A new study published by the University of Cambridge reveals that medieval Augustinian saints performed 'green-fingered' miracles, such as restoring swampy areas to fertility and healing diseased livestock. The research challenges major assumptions about the Catholic Church's forgotten early history.
A new study identifies genetic variants influencing both addiction risk and lower educational attainment. The researchers found a subset of genetic variants linked to substance use disorders and poorer health outcomes.
A UK-based study found that epilepsy can be a primary cause of death in people with intellectual disabilities, with those from ethnic minorities living in the UK being particularly at risk. The research highlights significant disparities in care and service provision, calling for systemic changes to prevent avoidable deaths.
A systematic review and network meta-analysis of 76 randomised controlled trials found that slow tapering of antidepressants combined with psychological support prevented relapse over the following year to a similar extent as remaining on an antidepressant. This approach could change how coming off antidepressants is managed globally.
A global survey of ECT recipients found that 84% reported childhood adversities, but only 32% had mental health services address these issues. Similarly, 81% reported recent stressors, with only 34% being asked about them.
A new seaweed-based carbon catalyst has been developed that can rapidly break down antibiotic norfloxacin in water without using toxic metals or sulfur chemicals. The catalyst, made from kappa carrageenan and doped with nitrogen and sulfur, shows high specific surface area and degrades antibiotics through non-radical pathways.
A new report highlights the surge in child sexual exploitation and abuse online, with AI-generated material increasing by 1,325% in a year. The WeProtect Global Alliance's Global Threat Assessment 2025 provides a practical tool for technology companies and governments to tackle the crisis.
Researchers developed an AI tool to identify patients with undiagnosed Alzheimer's disease using electronic health records, addressing underdiagnosis and healthcare inequities. The model achieved sensitivity rates of 77-81% across diverse populations, promoting fairness while maintaining high accuracy.
Researchers developed a non-invasive blood test to detect genetic material shed by tumors, which can identify adverse events related to immune checkpoint inhibitor therapy. The test found evidence of multi-organ injury in patients with immune-related adverse events, suggesting that the clinical syndromes may represent only a small frac...
Researchers used satellite data to study the 2025 Myanmar earthquake, which struck along a geologically 'mature' fault. The study found that the energy released by the earthquake was highly focused and came right to the surface, potentially leading to more intense ground shaking near the fault line.
The company's AI tool, RECTIFIER, uses generative AI to screen patients for clinical trial eligibility, significantly outperforming manual screening in accuracy and efficiency. The tool has been shown to more accurately identify eligible patients and reduce the burden of manual chart review in various healthcare settings.
A Montana State University economist's research found that wetland restoration through the Agricultural Conservation Easement Program can reduce ammonia and nitrogen concentrations in local waterways, resulting in decreased costs for communities. This can lead to tangible savings of up to $17,000 per year in smaller rural towns.
A new Mayo Clinic study found that an off-the-shelf dual-antibody therapy generates deep and durable responses in extramedullary multiple myeloma. In a trial of 90 patients, 79% responded to treatment, with nearly two-thirds maintaining disease control at one year.
Researchers used CRISPR technologies to discover previously unannotated DNA stretches in the 'dark genome', which control cell response to mechanical properties of their environment. This work could lead to new therapeutic targets for illnesses involving changes to tissue mechanics, including fibrosis and cancer.
A new mathematical model developed by University of Maryland researchers can help public health officials design effective vaccination and cancer screening policies for HPV-related cancers. The model suggests that expanding vaccine access, particularly to boys, could eliminate the disease in South Korea within 60-70 years.
Researchers developed multimodal models integrating imaging, clinical, and molecular data from TAILORx tissue biorepository for early-stage breast cancer. The models demonstrated enhanced prognostic performance compared to existing methods, highlighting their potential for personalized treatment decision-making.
The Institute for Quantum Innovation aims to accelerate discoveries from research to the real world, driving advancements in energy, national security, health, insurance, logistics, and critical infrastructure. The collaboration will provide best-in-class learning and research opportunities for students and faculty, putting Vanderbilt ...
Researchers in Australia and Aotearoa New Zealand will have expanded open access publishing options through a new three-year agreement. The partnership supports fully open access journals and enables the expansion of AI use in teaching and research.
Researchers have created a new crystalline material with unusual magnetic patterns that could be used for breakthroughs in data storage and quantum technologies. The team used structural frustration to generate complex patterns of spins, leading to the discovery of skyrmion-like spin textures.
Researchers at NYU Abu Dhabi have developed Spheromatrix, a platform that enables tumor models to be grown, frozen and stored for future use in cancer drug testing. The technology is made from specially engineered filter paper patterned to support the growth of tumor spheroids in a controlled manner.
Liu's project aims to translate optoretinography into a sensitive clinical biomarker for retinal disease assessment. The fellowship supports interdisciplinary problem-driven research and translation of new technologies into clinical practice.
The Association for Computing Machinery has named 61 new Distinguished Members, recognized for their contributions to AI for healthcare, data management, human-computer interaction, and other areas. The recipients include experts from top universities, corporations, and research institutions worldwide.
The Fuster Prevention Forum will teach clinicians effective ways to educate children, parents, and educators in their communities on nutrition, physical activity, and emotional well-being. The program aims to create a culture of prevention and promote sustainable, community-based initiatives.
A study of over 3,200 terrestrial mollusk species found that nearly half were described by non-local researchers, highlighting a neocolonial practice. This 'helicopter science' or 'parachute science' harms local researchers and can lead to less robust studies.
Researchers from Brazil confirm the safety and efficacy of Alternanthera littoralis (Joseph's Coat) in reducing inflammation and modulating inflammatory mediators. The study's findings support the plant's medicinal potential and suggest a safety profile at therapeutic doses.
A new study reveals that 16% of teens exposed to both phases of the Russo-Ukrainian war experience PTSD symptoms, while over 10% experience severe depressive symptoms. The study highlights the need for immediate and sustained attention to support Ukrainian youth's mental health needs.
A field experiment on Reddit examines what distinguishes passive from active users, testing interventions to increase participation. The results show that a heated environment can motivate the active minority to comment, while financial incentives and positive feedback increase activity.
Researchers at Ohio State University developed a new approach to immobilize extracellular vesicles in a way that mimics their interactions with tissues. This allows for the study of these particles and their complex interactions with cells, enabling potential applications in disease detection, drug delivery, and biomarker discovery.
A recent study by Tufts University researchers found that locally available foods with low monetary cost can also meet basic nutritional needs with minimal greenhouse gas emission. The study challenged the assumption that climate-friendly healthy eating requires paying more for premium products.
The American Academy of Neurology has issued a new guideline for the management of functional seizures, which are episodes that can look or feel like epilepsy or fainting. The guideline recommends psychological interventions such as cognitive behavioral therapy to increase the likelihood of achieving freedom from functional seizures.
A preliminary study suggests that GLP-1 drugs, used for diabetes and weight loss, may be linked to a lower risk of developing epilepsy. Researchers found an association between the use of these drugs and a reduced risk of epilepsy, with semaglutide showing the strongest correlation.
Recent research articles explore innovative methods for rehabilitating coral reefs, new observations of masquerading behavior in deep-sea squids, the rapid expansion of Sphagnum peat patches across Alaska's North Slope, trade-offs between protected areas and sustainable development goals, and a surprising first-time observation of moth...
Overleaf is introducing a new AI assistant that combines advanced capabilities with its intuitive editor. The tool helps researchers spend less time coding and more time producing high-quality work. The new features are available in Overleaf Labs and provide a research-focused writing assistant and a first-of-its-kind citation reviewer.
Researchers distinguish between medical and community-based approaches to safe supply, proposing a framework for better describing care models. The study aims to inform policy changes and improve access to care, decrease overdoses, and reduce stigma around people who use drugs.
Researchers model Baraitser-Winter syndrome using human brain organoids, finding altered actin genes lead to reduced brain growth and smaller size. The study reveals a single mutation in the cytoskeleton causes disruption in early brain development.
The MicroBooNE collaboration has ruled out the possibility of a light sterile neutrino, a hypothetical particle that had long been speculated as a solution to open questions in particle physics. This result narrows the field of possibilities for explaining one of today's biggest puzzles in neutrino physics.
The study reveals a new method to harness stray laser scatter to cancel out unwanted multi-photon emission, leading to a more efficient and secure single-photon line. This breakthrough could enable the development of advanced quantum computers and communication networks.
A new study by the University at Buffalo found that 12th graders who use two or more cannabis products are more likely to engage in binge drinking. The study suggests that certain modes of cannabis consumption, such as smoking and vaping, may be linked to higher risks of binge drinking.
A comprehensive review reveals AI's potential to predict resistance patterns, optimize antibiotic use, and strengthen early detection and intervention strategies. Machine learning and deep learning algorithms are transforming surveillance, diagnosis, treatment optimization, and drug discovery.
Researchers have identified two previously unknown circoviruses in short-finned pilot whales and orcas from the Caribbean region of the North Atlantic Ocean. The newly discovered viruses, named shofin circovirus and orcin circovirus, represent a distinct clade within the genus Circovirus.
A case report describes a woman with radiation-induced cellular changes in her Pap smear that mimicked cancer recurrence. The study emphasizes the importance of recognizing these changes to prevent misdiagnosis and unnecessary medical procedures.
This innovative module combines vibration-assisted penetration and real-time force sensing to reduce tissue damage and inflammation risks. The device achieves high precision and accuracy, making it suitable for biomedical applications such as neural probe implantation and single-cell puncture.
Researchers have uncovered clues about the ancient Hjortspring boat's origins, including a partial human fingerprint and carbon-dating results indicating it was built in the 4th or 3rd century BCE. The findings suggest that the boat may have come from the Baltic Sea Region, where pine forests were more abundant.
A newly developed wearable sensor uses polarized light to improve photoplethysmography (PPG) signal accuracy across different skin tones. The device splits light into two channels, detecting co-polarized and cross-polarized signals to filter out superficial scattering and capture stronger signals from deeper tissue.
The Universidad Carlos III de Madrid has been awarded two prestigious ERC Consolidator Grants to tackle major challenges in space propulsion and social mobility. The ROCINANTE project will develop more efficient space thrusters, while the EXKIN project will study intergenerational mobility and inequality.