Researchers have identified Rb1 as a predictive biomarker for a new therapeutic strategy in some breast cancers. The study found that simultaneous inhibition of ATR and PKMYT1 triggers cell death in Rb1-deficient breast cancer models, leading to tumor shrinkage and improved survival.
A recent international study coordinated by the Sant'Anna School of Advanced Studies found that preserving bilateral cardiac vagal innervation is an anti-aging factor. The right cardiac vagus nerve helps preserve cardiomyocyte health independently of heart rate, suggesting a new strategy for long-term heart protection.
A recent survey of pediatric surgeons reveals that AI adoption is hindered by ethical concerns over accountability, informed consent, and data protection. Despite potential benefits, only one-third of respondents have used AI in clinical practice, with most focusing on tasks like literature searches.
A study found that prescription stimulants primarily affect brain's reward and wakefulness centers, rather than attention circuitry. This leads to improved focus through increased motivation and reduced sleep deprivation effects.
Professor Keisuke Fujii, a researcher at The University of Osaka, has been selected as one of the Quantum 100 for his work on quantum computing. He was honored with this recognition in 2025, the centennial year of quantum mechanics.
Researchers developed a computational framework to identify effective catalysts for producing hydrogen peroxide from water and electricity. The approach successfully predicted key reaction properties across diverse materials, leading to the discovery of promising candidate lithium scandium oxide.
HSE economists found that AI models like ChatGPT and Claude tend to play 'too smart' and lose in strategic thinking games by assuming a higher level of logic in people than is actually present. The study replicated results from previous human participant experiments, showing LLMs adapt to opponents with varying levels of sophistication.
Researchers reviewed magnetic materials preparation, structural design and actuation systems for medical applications, highlighting potential in targeted drug delivery, minimally invasive surgery and disease diagnosis. Despite challenges, the authors emphasize magnetic soft robots' potential to reshape future healthcare practices.
Researchers propose a theoretical model to analyze adhesion and escape phenomena during low-velocity impacts between charged dust particles and spacecraft. The study focuses on the interaction between charged particles and spacecraft within a plasma sheath, considering significant size differences.
A newly developed AI model accurately predicts blood loss in patients undergoing high-volume liposuction, showing excellent agreement with estimated volumes. The model's 94% accuracy may help make surgery 'smarter and safer' by informing perioperative management and reducing the risk of complications.
The NSLLM framework transforms conventional LLMs into neuromorphic models by performing integer spike counting and binary spike conversion, enabling analysis of information processing. This approach achieves significant energy efficiency and improved interpretability through the use of neural dynamical representations and biologically-...
A team of HSE researchers has created a comprehensive map of quadruplexes, unstable DNA structures involved in gene regulation. The study reveals that quadruplexes function in pairs, regulating tissue-specific genes in healthy tissues and cell growth and division in cancerous tissues.
A study analyzing corporate ESG reporting through data mining reveals a significant trend toward the homogenization of reports, with greater emphasis on social and governance issues. The findings suggest that companies are adopting similar ESG frameworks, which can enhance legitimacy but limit innovation.
Researchers discovered that MHP films exhibit triboluminescence when scraped with metals like copper, gold, or platinum, due to friction-induced charge transfer. This phenomenon is universally observed across commonly studied MHP films. The enhancement of PL is attributed to the accumulation of positive charges on the perovskite surfac...
Researchers develop experimental drugs that encourage mitochondria in cells to work harder and burn more calories. The findings offer a framework for designing safe and effective weight-loss treatments with potential benefits for metabolic health and neurodegenerative diseases.
A team of researchers at Osaka Metropolitan University has created two models to detect and fix common labeling errors in large radiographic collections. The models achieved high accuracy rates for body-part classification and projection/orientation detection, showing promising results for improving deep-learning models in medical AI.