Researchers discover that tau protein and beta-amyloid, key pathological hallmarks of Alzheimer's, affect brain circuits in distinct yet synergistic ways. This study suggests a potential breakthrough in treatment strategies by highlighting the need for dual-targeted therapies.
A study by University of Texas at Austin professor Lisa De Simone found that internal disclosure laws lead to more jobs and save taxpayers. External disclosure laws have little to no impact on job creation. The research analyzed data from 27 states and 48,243 subsidies.
Researchers at UC Davis have successfully synthesized ibogaine and its related compounds using a new, efficient method. The study's findings suggest that these analogues may be useful in treating substance use disorders and other conditions, and highlight the potential for safer and more effective medicines.
New research highlights the connection between income inequality and health and education disparities, increasing support for economic reform. The study reveals that understanding these disparities can lead to a greater willingness to reduce inequality.
Researchers at UC3M developed a new soft joint model that enables versatility of movement, adaptability, and safety in robots. The asymmetrical triangular structure allows for greater bending angles with less force, providing operational protection and increased safety in human-robot interactions.
Researchers at Tampere University developed a new method to detect congestive heart failure using inter-beat intervals measured by smartwatches and heart rate monitors. The accuracy of the method was found to be 90% in distinguishing patients with congestive heart failure from healthy control subjects.
Researchers developed a highly efficient and powerful SOT-MRAM solution using Orbital Hall Effect, eliminating rare materials. This innovation offers a transformative step forward for technologies from smartphones to supercomputers.
The Micro Immune Response On chip (MIRO) replicates tumours and their environment, allowing researchers to study the efficacy of immunotherapy treatments. This technology has been tested with breast cancer samples and shows promise in understanding how the immune system interacts with tumours.
Researchers tracked Painted Lady Butterflies' migration patterns, finding distinct behaviors between northern and southern populations. The study suggests environmental factors influence migratory behavior, with some butterflies traveling up to 4,000 kilometers across the Sahara Desert.
A new study reveals that 93.2% of pediatric allogeneic hematopoietic stem cell transplantation (HSCT) recipients experience infections post-transplant, with viral infections being the most common. The study identifies key risk factors and highlights the importance of personalized approaches in infection management.
Researchers Rob Martienssen and Thomas Gingeras analyzed maize and teosinte genomes to identify regulatory regions controlling gene expression. They found hundreds of thousands of enhancers and super enhancers that were strongly selected during domestication 9,000 years ago.
Research on Earth's frozen places reveals severe changes due to climate change, including ice-free Arctic Oceans and quadrupled melt zones in Greenland.
Researchers at ETH Zurich discovered tiny ice quakes deep inside ice streams, explaining the discrepancy between simulations and satellite measurements. The findings impact sea-level rise estimates and may reveal fault planes in ice cores, providing a better understanding of ice stream deformation.
Residents of Ontario with cannabis use disorder had a significantly higher risk of death compared to the general population. The findings highlight the importance of addressing cannabis use disorders, especially as global trends toward cannabis legalization continue.
Research by University of Washington oceanographers found that whale excrement contains significant amounts of iron, a vital element for phytoplankton growth. The study suggests that the decimation of baleen whale populations may have had larger biogeochemical implications for the Southern Ocean ecosystem.
A global 'sisterhood' of citizen scientists sheds light on the complex vaginal microbiome, highlighting associations between microbial composition and clinical conditions like preterm birth and urinary tract infections. The study emphasizes the importance of considering whole complexity and continuity in vaginal microbiota composition ...
A team of researchers at Mass General Brigham has discovered that granzyme K activates the complement system against own tissues, driving inflammation and tissue damage. Inhibiting this pathway could preserve anti-microbial functions while targeting chronic inflammatory diseases.
Researchers created a tool to target agroforestry where it provides the greatest environmental benefits while being economically viable, socially acceptable. The map identifies areas with high impacts on soil erosion, water quality, climate, and profitability for lands not suitable for other crops.
Researchers found consistent insect damage on fossil leaves from Argentina and modern gum tree leaves from Australia, suggesting insects tracked their food source through time. The study provides insight into the ecology of ancient forests and could lead to the discovery of new insect species.
The Rising Black Scientists Awards recognize four winners who have harnessed features of their lives to inspire their career and uplift communities. The awardees include Jheannelle Johnson, Victor Ekuta, Kenna Gloria Agbugba, and Nyasha Milanzi, who will receive $10,000 for their science and a travel grant.
Researchers used neutrons to study the magnetic structure of layered perovskites, resolving a long-standing mystery. The study reveals a spiral magnetic structure, which is essential for understanding the material's promising magnetic and electric properties.
A new method called periodic cooking optimally cooks both the yolk and white of a boiled egg, resulting in an evenly-cooked egg with higher nutritional content. The approach involves alternating the egg between boiling water and a cooler temperature, yielding soft yolks similar to sous vide eggs.
A new study by IIASA scientists suggests that a mix of policy measures and behavioral changes can significantly reduce GHG emissions from energy use in buildings and transport. The strategies could reduce CO2 emissions from buildings by 51-85% and transport by 37-91% compared to current policies.
Arati Dasgupta, a leading atomic and plasma physicist at NRL, has been elevated to IEEE Fellow for her groundbreaking research in high-energy density plasmas, atomic physics, and radiation materials. Her work has significantly advanced our understanding of extreme environments and their applications.
A study by the University of Tokyo reveals that fine particulate pollution PM2.5 exacerbates pre-existing conditions in elderly populations, leading to higher hospitalization rates and premature mortality, with significant socioeconomic challenges for rural regions with limited medical resources.
A new single-photon time-of-flight LiDAR system can acquire high-resolution 3D images of objects or scenes up to 1 kilometer away, offering improved surveillance and monitoring capabilities. The system uses a superconducting nanowire single-photon detector and achieves a higher spatial resolution than previous systems.
Research shows that front-of-package food labels professing 'healthy' contents can decrease consumers' willingness to pay unless supported by FDA backing and explanation. The study found a 18% discount for yogurt labeled as 'healthy', while both 'healthy' and 'great taste' labels led to a 25% discount.
A Virginia Tech research team has made significant progress in understanding the role of physical properties in tuning the body's immune responses. By modifying biomaterials' size, shape, and stiffness, they aim to enhance immune cell behavior and stimulate antitumor immune responses.
Researchers used CRISPR/Cas9 to study the gene function of adenine phosphoribosyl transferase in beans. They found two functional mutants with distinct roles: one affects adenine recycling and the other regulates cytokinins, essential for root growth and nodules.
A University of Liverpool-led study found that climate warming causes a 28% decline in tree growth since 2005 due to temperature-driven changes in seed production. The study also reveals that under warmer temperatures, beech trees shift resource allocation from growth to reproduction.
A groundbreaking research project is exploring the unique role of kittiwakes in urban ecology, aiming to establish a governance framework that promotes harmonious coexistence between humans and wildlife. The study will employ various tools, including machine learning and GIS, to assess the impacts of urban development on biodiversity.
Researchers at Case Western Reserve University developed a method to detect inflammation using antibodies, potentially leading to blood tests for disease-specific biomarkers. The breakthrough also holds promise for drug discovery.
Researchers at TUM found that cystic fibrosis causes changes in the immune system as early as birth, leading to frequent inflammation and infections. These changes are not affected by CFTR modulator therapies.
Researchers at Arizona State University propose a unifying explanation for Alzheimer’s disease, focusing on the role of chronic stress granules in disrupting gene activity. The condition causes massive changes in gene expression, affecting every known neuropathology and clinical manifestation.
Physicists have built a new type of digital-analogue quantum simulator that can study physical processes with unprecedented precision and flexibility. The simulator combines both digital and analogue operating modes, enabling it to be applied to various problems in solid-state physics, astrophysics, and more.
A comprehensive map of Plasmodium knowlesi genes essential for blood infections has been generated, providing insights into drug resistance and informing the development of new therapeutics. The study identified molecular requirements for parasite growth and pinpointed specific genes causing resistance to current antimalarials.
In Japan, breast cancer screening participation rates dropped significantly during the pandemic, affecting specific subgroups such as those aged 45-49 and living in towns/villages. The overall rate declined from 48.3% to 47.1%, with municipalities seeing a decrease but worksites an increase.
Researchers analyzed data from python contractors to identify regions and conditions that increase python removals, providing guidelines for targeted surveys. The study found optimal conditions, including time, temperature, and survey duration, leading to improved efficiency in python detection and removal efforts.
Scientists have discovered a way to turn ordinary liquids into epsilon-near-zero (ENZ) materials by interacting them with intense femtosecond laser pulses. This creates a new class of materials with tunable light propagation properties, opening up possibilities for advances in optical sensing and communication.
Farmers in African mountains report alarming changes in local weather patterns, leading to reduced crop yields and food insecurity. The study highlights the need for tailored adaptation strategies that consider environmental, social, and political dynamics of each region.
Researchers developed a one-page medication handout that quantifies a drug's risk and benefits, improving patient understanding and decision-making. The study compared this handout with the FDA's version and found it to be more effective in conveying complex information.
A Mississippi State University scientist has discovered 16 new species of grasshoppers living in the thorny scrubs of U.S. and Mexican deserts, showcasing the thriving biodiversity in arid ecosystems. The newly uncovered species are native to the southern U.S. and Mexican deserts and were described in a recent scientific journal article.
Researchers tracked 131 juvenile sea turtles and found they may be active swimmers during their early life stage, challenging existing hypotheses. The study provides important data for assessing risks from human activity and informing conservation efforts.
The Physicians Committee for Responsible Medicine is urging lawmakers to phase out federal support for animal research and reinvest funds into human-based models. Over 80% of respondents agree that animal-based research should be phased out in favor of more effective approaches.
Researchers mapped the precise brain mechanisms that enable animals to overcome instinctive fears, revealing two key components in this learning process. The study found that a brain structure called the ventrolateral geniculate nucleus (vLGN) stores learning-induced memories and is triggered by the release of endocannabinoids.
Researchers at KAIST have discovered a molecular switch that can induce cancer reversal by capturing the moment of critical transition before normal cells become irreversibly cancerous. The technology uses single-cell RNA sequencing data and computer simulation analysis to identify the molecular switch.
The ISSCR International Symposium will commemorate the 20th anniversary of iPSC discovery, highlighting breakthrough achievements and new research advances. The event aims to celebrate the transformative power of scientific curiosity and its potential to unlock cures for previously untreatable diseases.
Researchers discovered that mantis shrimp's armored clubs selectively block high-frequency sound waves to prevent damage. The layered patterns act as a shield against vibrations, enabling the shrimp to preserve its striking ability over multiple impacts.
A team of physicists has successfully described the inside of a proton using quantum information tools, revealing maximal entanglement and predicting particle production. The new formalism correctly reproduces all available experimental data, providing insights into the complex interactions within protons.
The American Heart Association and the National Football League are awarding $1,000 grants to support physical activity in local schools. The grants aim to encourage students to move for at least 60 minutes each day through the NFL PLAY 60 app, available on iOS and Android devices.
Researchers found a high agreement between EEG and fMRI in identifying brain regions activated during language tasks. EEG-guided tDCS improved picture-naming speed in participants, suggesting its potential for innovative therapies.
A new genetic mutation, RUFY1-RET fusion, was discovered in a patient with stage IV CD-74-ROS1 fusion NSCLC who developed resistance to lorlatinib. The finding highlights the importance of ongoing genetic testing to guide therapy decisions.
A new study using single-cell transcriptome analysis investigated the expression and dysregulation of RNA-binding proteins in rheumatoid arthritis. The research found that RBP regulation differs between RA and osteoarthritis, with specific RBPs involved in alternative mRNA splicing and translational control.
A study published in JAMA Network Open found that young adults with Type 2 diabetes and low income have a significantly higher mortality risk compared to those with high income. The research team analyzed over 600,000 patients and found that patients under 40 with low income had a 2.88 times higher mortality risk.
A novel underwater light system, UZELA, enhances local zooplankton density and increases feeding rates of coral, making them stronger and more resilient against environmental threats. The device can be powered for half a year on a single battery and can optimize a coral's feeding time by operating for one hour after dusk.
A multinational research project, led by UC Merced and BioSCape, used NASA aircraft to collect data on ultraviolet, visual, thermal and other images over South Africa's Greater Cape Floristic Region. The data provided a comprehensive look at the region's biodiversity and ecosystem function.
A recent study published in Nature Communications reveals polarized global landscape and 'orphaned' SDG indicators affecting nations' trajectories toward sustainable development. The research provides insights into the progress and disparities of countries toward achieving the Sustainable Development Goals, highlighting areas where act...
Scientists have discovered a distant, two-lobed radio jet that spans an astonishing 200,000 light-years at least, twice the width of the Milky Way. The team used a combination of telescopes to detect the jet and measure its properties, including the mass of the quasar producing it.
The Minoritised Life Scientists Future Forum conference will take place in March 2025 at ICC Birmingham, aiming to foster an inclusive space for underrepresented life scientists. The event offers mentorship schemes, networking opportunities, and inspiring speakers from diverse backgrounds.
The Kraft Center for Community Health at Mass General Brigham is awarding the Kraft Prize to recognize transformative organizations or innovations making a measurable impact on community health. The $100,000 prize includes travel accommodations and support from Mass General Brigham's Innovation MESH Network.