A University of Barcelona study has identified the RBFOX1 gene as a central hub regulating nearly 20 genes linked to depression, anxiety, irritability, and neuroticism. This genetic overlap could help explain why these disorders often appear together in the same person.
A noninvasive DNA blood test can identify patients with metastatic castration-resistant prostate cancer most likely to benefit from <sup> 223 </sup> Ra radiopharmaceutical therapy and monitor their progress. The test showed associations between ctDNA profiles and clinical outcomes, including biomarker response and overall survival.
A new study reveals that Republican lawmakers sponsored 86% of antivaccine bills introduced in state legislatures after the COVID-19 pandemic. Meanwhile, Democratic lawmakers supported provaccine bills, highlighting partisan polarization's impact on vaccine access and public health.
A large retrospective study found that semaglutide and other GLP-1 drugs did not increase or decrease the risk of developing a blinding eye condition in adults with type 2 diabetes. The study analyzed data from over 200,000 patients and found no significant difference in the risk of neovascular age-related macular degeneration.
The CLEVER project aims to create a comprehensive fungal EV atlas, investigating the role of extracellular vesicles in communication between pathogenic fungi and the human body. The research may lead to more accurate diagnosis and improved treatment of fungal infections.
Researchers have made significant breakthroughs in targeted radiation therapy for pancreatic cancer, PARP inhibitor treatment, and Alzheimer's disease detection. New PET-based scores may predict prostate cancer outcomes, while blood cell mutations are associated with side effects in advanced prostate cancer patients.
A new study identifies the ecological conditions necessary for biodiversity offsetting to achieve conservation goals. The research highlights the importance of large-scale restoration areas and protected landscapes in achieving long-term biodiversity outcomes. Successful compensation requires policies aligned with ecological reality, p...
Researchers are exploring innovative technologies to improve disease diagnosis and treatment. AI models have shown promise in speeding up detection and treatment discovery for rare diseases. Meanwhile, electronic noses are being developed for non-invasive cancer screening.
A long-term study of 1,200 women in eastern Massachusetts found that those living in disadvantaged neighborhoods faced faster declines in heart health and worse cardiovascular risk before menopause. The research highlights the importance of addressing socioeconomic factors in preventing heart disease.
The Lurie Children's Mood, Anxiety, ADHD Collaborative Care (MAACC) program prepares pediatricians to manage mental health conditions on their own. This enables more children to access care despite the shortage of pediatric mental health professionals.
Researchers at USF Health Morsani College of Medicine have identified a promising strategy to protect cardiac function in people with Duchenne muscular dystrophy. The study found that the experimental drug Setanaxib preserved cardiac function and reduced scarring, suggesting NOX4 as a potential therapeutic target for future treatments.
A new enzyme-free test strip detects mosquito-borne viruses with high sensitivity, promising rapid field testing and infection control in resource-limited regions. The multisite bridging-mediated lateral flow immunoassay outperforms conventional methods, offering a promising diagnostic platform for outbreak surveillance.
A new study by Queen Mary University mathematician Professor Ginestra Bianconi proposes a perspective on the deep question of how the Universe can become increasingly structured while obeying the second law of thermodynamics. The Gravity from Entropy theory suggests that gravity and spacetime may have an intrinsic thermodynamic and inf...
Researchers successfully edited the genome of Culicoides biting midges using CRISPR-based technique, enabling new research on disease transmission and control. The method provides a practical approach for genetic manipulation in these insects.
A University of Bonn study finds that government regulations and financial incentives can significantly improve land quality and mitigate soil degradation. Effective policies also rely on strong government institutions and sufficient funding to monitor compliance and enforce regulations.
A new study assesses the long-term effects of China's Shan-Shui Initiative, finding that vegetation greenness increased significantly in 14 project areas. The integrated remote-sensing index revealed more nuanced regional responses, with forests and grasslands playing distinct roles across different ecological contexts.
The ESA's 2026 Annual Meeting will present new findings on wildlife ecology, focusing on the ecological relationships between animals, habitats, and human activities. Researchers will examine topics such as predator recovery, species declines, and rewilding, highlighting how wildlife ecology informs conservation strategies.
A growing number of European countries are detecting gonococcal strains resistant to ceftriaxone, posing a significant challenge for treatment options. Early detections are associated with importation from South-East Asia, and strengthening prevention is essential.
Elena Zinchenko joins ULRI with extensive experience in program development, stakeholder engagement, and mission-driven innovation. She aims to strengthen the organization's ability to prevent harm and save lives through safety science research excellence.
Research reveals that job characteristics, including schedule flexibility and indispensability, influence how couples balance work and family responsibilities. The study found that women were more likely to make adjustments to support family needs, but this effect was attributed to differences in job characteristics rather than gender.
Researchers at ICTA-UAB developed a public tool to explore climate gentrification vulnerability across 36 municipalities in the Barcelona metropolitan area. The map shows that greener, less densely populated areas are at higher risk due to rising temperatures and heat exposure.
A new study published in Chinese Neurosurgical Journal found that real-time MRI and brain function monitoring during neurosurgery can improve the removal of tumors affecting the corpus callosum more effectively and safely. This multimodal approach gave patients about 30 extra months after treatment before the tumor grew back or worsene...
A new study uses a thermal analysis technique to distinguish between different sources of organic carbon transported by rivers after extreme events, such as earthquakes and storms. The findings show that these events can continue to influence carbon transport in river systems for over a decade.
A study found that many weight-loss clinics and medical spas continue to offer compounded GLP-1 medications after FDA shortages ended. Researchers identified some suppliers lacking sterile compounding licenses or recent disciplinary actions related to sterile compounding practices.
Researchers from the University of Osaka have found a way for cells to quickly reactivate gene expression after being stressed by heat. They discovered that the CLK1 protein is regulated by phosphorylation and dephosphorylation, which controls its localization to nuclear stress bodies.
Scientists at HZDR have developed two new processes to degrade PFAS: one uses hydrodynamic cavitation and the other employs cold atmospheric plasma. These methods show promise for reducing PFAS release into water bodies, a significant step towards securing Germany's drinking water supply.
Researchers identified a ROS-dependent Jak2/Stat3 pathway that triggers hepatic inflammatory responses in chronic HBV infection. Mitochondrial respiratory dysfunction leads to elevated ROS, which activates the Nrf2–IL-6/IL-8–Jak2/Stat3 axis.
Helical carbon nanotubes offer unique geometrical characteristics, enabling improved mechanical entanglement with host-resins. Chemical functionalization enhances their molecular interactions and dispersion-uniformity, leading to enhanced composites properties.
A joint research team from SNU and University of Seoul developed a programmable photonic integrated circuit that can slow light on demand. This innovation enables the storage, delay, and control of light within a single photonic chip, overcoming limitations in optical computing technologies.
Researchers from HKUST have developed a molecular interface engineering approach to improve the efficiency and durability of perovskite tandem solar cells. The new strategy enables precise control over crystallization, reduces energy loss, and promotes charge transport, leading to higher power conversion efficiencies.
Same-day naloxone availability differs across pharmacy types, with independent and medical-affiliated pharmacies facing challenges in rural and underserved areas. Expanding pharmacist education is crucial to improve naloxone access following OTC approval.
The article reports on the preparation of ZnO nanoflakes modified with noble metals Au, Pt, and Pd via UV reduction, resulting in enhanced gas-sensing properties. The Au/ZnO material demonstrated superior response to isopropanol and investigated potential sensing mechanisms.
Researchers from Peking University have reviewed the role of synthetic aperture radar (SAR) imaging geodesy in monitoring glacier velocity, which helps assess how glaciers respond to climate change. SAR offers a non-contact alternative to field-based approaches, providing high-resolution measurements over large and difficult-to-access ...
A cohort study found that increased problematic social media use during mid-adolescence was directly associated with higher ADHD symptoms. The association was strongest among male participants.
Researchers introduced an opto-thermoviscous strategy to generate stable 3D helical thermoviscous flows, allowing robust out-of-plane rotation and manipulation of various micro-objects. This method enables multiview 3D microscopy by leveraging kinematic nature of thermoviscous manipulation.
Researchers at Tohoku University have developed high-performance silk with 50% greater tensile strength and reduced shrinkage after wetting. By altering silkworm diets, they added plant-derived cellulose nanofibers to improve silk fibers' properties.
The Herbularyo card game combines Filipino folk healing traditions with organic chemistry, teaching students about medicinal plants and their therapeutic properties. The game has been shown to be an effective learning tool, increasing student engagement and understanding of the subject.
Researchers have identified a sensitive isotopic biomarker for early anemia detection using copper stable isotope ratios (δ⁶⁵Cu) in pediatric serum. The study also uncovered distinct serum metallomic patterns linked to body mass index (BMI), including a strong positive association between serum lead levels and increasing BMI.
Researchers developed a class of senary Fe–Co–Ni–Si–B–Y MPEAAs with high saturation magnetization, exceptional thermal stability, enhanced microhardness, and acceptable corrosion resistance. These materials have potential applications in soft magnetic alloys for offshore wind power systems.
The GLP-1 RA market experienced a surge in demand following the semaglutide and tirzepatide shortages. Compounded GLP-1 RAs sourced from unlicensed facilities pose clinical and regulatory challenges.
A technology has been developed that allows artificial intelligence to inversely determine process conditions for quantum-dot light-emitting diode devices. The technology roughly doubled efficiency and extended operational lifetime more than 40-fold when applied to actual devices.
Researchers developed smart hydrogels with tunable mechanical properties, environmental responsiveness, and biodegradability for tissue regeneration. These advanced scaffolds have potential in emerging areas like drug delivery systems and wound dressings.
A team of researchers has identified an accelerator of extremely high-energy cosmic-ray protons, called a proton PeVatron, in the Milky Way galaxy. The discovery was made possible by combining data from multiple experiments, including Tibet AS gamma, LHAASO, Fermi-LAT, and Chandra X-ray Observatory.
The IRP1/ARID3A complex suppresses ferroptosis and promotes chemoresistance in pancreatic cancer by epigenetically silencing cytoglobin (CYGB). Restoration of CYGB expression reverses these effects, sensitizing tumor cells to ferroptosis and improving treatment outcomes.
Researchers developed a controllable assembly strategy to create BaCrO4@B core-shell energetic microspheres with precisely engineered spatial structures. The new method achieved uniform elemental distribution, preserved crystal structure, and continuous shell coverage, resulting in enhanced combustion stability and energy output.
The research team developed a novel X-type quasi-two-dimensional perovskite emitter that enables thermodynamically controlled crystal growth and precise crystallization control in vacuum deposition. This enabled the creation of highly uniform, high-efficiency, and high-color purity PeLEDs.
Researchers traced fire origins using network analysis of satellite observations, finding large fires often started from multiple locations. The study highlights the role of environmental conditions in determining where fires originate, which may challenge previous understanding of tropical forests' resilience.
Researchers developed DMCGuard to address inconsistent security policies across various IoT management channels. The framework provides a robust solution for preventing unauthorized access in smart environments without modifying underlying protocols.
A research team led by Prof. Jun Won Choi of Seoul National University College of Engineering independently developed SafeDrive, an end-to-end autonomous driving AI model. The work has been recognized for its impact on the field of autonomous driving technology.
A new study reveals critical fine-scale spatial heterogeneity of mesozooplankton across three brackish bays of the Central and Eastern Baltic Sea. Salinity and temperature drive distinct zooplankton assemblages, with clear inter-bay community separation emerging.
Researchers developed an ultrasensitive SERS-based method for Pb2+ detection using L-cysteine-functionalized bismuth nanoparticles. The method achieves a low detection limit of 0.005 nmol⸱L−1, outperforming conventional lead ion detection techniques.
Researchers developed an attention-guided Transformer model that learns unique strengths of each satellite mission, preserving differences in constellation design and observation geometry. The approach achieved high correlation coefficients and low RMSE values against references, especially in arid regions.
At CPIC 2026, Insilico Medicine's Dr. Alex Zhavoronkov and Dr. Feng Ren presented on their approach to AI-driven life sciences, leveraging the Pharma.AI platform for agile translation and closed-loop validation. The duo emphasized the importance of technological breakthroughs and clinical validation in shaping the future of R&D.
A new DNA-based strategy has been developed to tackle gum disease, which is one of the most common chronic inflammatory diseases worldwide. The multifunctional nanotherapy effectively targets bacterial infection, suppresses oxidative stress, and promotes bone formation, showing promising results in preclinical studies.
A new layered crystal, TlFe1.6Se2, combines high thermoelectric power factor with exceptionally low thermal conductivity, offering a promising strategy for designing next-generation thermoelectric materials. The material's unique electronic properties and Fe-vacancy ordering enhance its performance.
Researchers developed a perception-driven display strategy that balances real-world brightness and virtual image quality. The technology improves real-world visibility while maintaining convincing appearance for virtual content under different lighting conditions.
Researchers found that tau buildup in PSP affects brain networks involved in thinking, including the prefrontal cortex and anterior cingulate cortex. The study suggests that symptoms arise from both local tau-related damage and remote disruption of a broader cognitive network.
Researchers found that repetitive neuronal stimulation transforms the identity of mature neurons, inducing cellular dematuration and widespread chromatin accessibility changes. The study suggests an 'intermediate state' of high plasticity, where specific configurations may depend on how strongly and often neuronal activity is applied.
Researchers found that as salinity increases in freshwater environments, microbial communities lose diversity due to faster-growing strains taking over, but maintain overall growth rates. This effect is also observed in natural ecosystems across different environments.
Kyushu University researchers have developed prototype thin-film electronic modules that can automatically connect and disconnect with each other. The modules use a kinetic electronics approach, integrating actuators and circuits on the same thin-film to create an electromechanical docking mechanism.