Researchers at Uppsala University recalculated the Sun's silver content using a new model that predicts 55% more silver than previous estimates. This resolves a long-standing problem of missing silver in the solar system and improves our understanding of how elements are produced in stars and incorporated into planets.
The Osaka Metropolitan University, K.K. DNAFORM, and INRB have developed a portable rapid diagnostic system for Ebola virus disease caused by Bundibugyo virus. The system utilizes the GenPad POCT platform and can be used near outbreak sites without power infrastructure.
Researchers studied six royal mummies from the Middle Kingdom and found evidence of strong muscle attachments and healed fractures, indicating the princesses were skilled archers. The study provides insight into the daily lives of these royal women, revealing they faced hardships despite their high status.
Researchers have developed NovoTags, synthetic fluorescent protein tags that can bind to bright fluorescent dyes with high specificity and affinity. These tags enable multicolor imaging of proteins inside cells, expanding the toolkit for advanced light microscopy techniques.
Researchers discovered that only three water molecules are sufficient to trigger a configuration transformation of the core skeleton from Sr2(μ2-OH)2(HO)1 to Sr2(μ2-OH)3, providing new insights into hydration mechanisms. This structural transition is driven by deformation energy and stabilizes the structure through rearrangement of hyd...
Researchers developed defect-rich silicon-carbon composite anodes with initial discharge capacities exceeding 6,500 mAh g⁻¹, outperforming conventional silicon-anode expectations. AI-assisted design optimized the formulation, revealing a trade-off between capacity and efficiency.
Researchers from Tohoku University have created a stable version of boron graphene on the surface of a three-dimensional crystal, revealing a new quantum state. The discovery could lead to more energy-efficient electronic devices and unlock entirely new quantum phenomena.
Researchers developed a new monitoring method for Sea-Based Joint Precision Approach and Landing System (SB-JPALS) using multiple reference receivers and a Boolean collaborative decision rule to detect ionospheric gradients. The approach improved monitoring sensitivity by 12.0% compared to conventional methods.
Research based on China's Chang'e-6 samples reveals that Earth's magnetosphere has shaped the difference in solar wind speeds and energies striking the Moon's two hemispheres. The study found that the lunar far side underwent stronger isotopic fractionation, resulting in preferential enrichment of the heavier isotope.
A new MoS2-based catalyst has been developed to overcome the limitations of conventional MoS2 catalysts in hydrogen evolution reactions. The catalyst, created using a dual-site substitution strategy, achieves outstanding performance at large current densities in acidic electrolytes.
Scientists at Tohoku University identified an optimal lithium concentration that allows for even lithium deposition and a stronger protective layer on the battery's surface. This discovery enables the development of safer, longer-lasting, high-energy-density rechargeable batteries.
A study by Pompeu Fabra University, ONT, and Vall d'Hebron Hospital reveals that public investment in liver transplants not only improves patient survival but also generates a positive social and economic return. The study estimates that liver transplant patients contribute over 100 million euros to the Spanish economy annually.
Researchers at Tohoku University have discovered a previously unknown pathway for B-cell development in chickens, bypassing the bursa of Fabricius. The discovery reveals that B cells originate in the bone marrow and migrate to the cecal tonsils, establishing an IgA-mediated intestinal barrier.
Researchers discovered that phosphorus plays a synergistic promoter role in evolving NiFe phosphides, accelerating oxygen evolution and suppressing dissolution of iron ions. The breakthrough catalyst delivers exceptional OER activity, achieving low overpotentials and superior reaction kinetics.
Researchers at Adelaide University developed a laser-based technology to detect toxic methanol in sealed spirit bottles, even through colored glass. The system uses Raman spectroscopy to identify the unique chemical 'fingerprint' of a liquid through its packaging.
The book offers practical, research-informed strategies to help pre-service and early career teachers navigate professional challenges. It explores how teachers can prepare for new roles, embed Aboriginal perspectives, and design inclusive learning opportunities.
Researchers used trans-tympanic infrared laser stimulation of the cochlea to evoke reliable auditory-guided behaviour in awake animals, without invasive procedures or genetic modification. The study found that laser-evoked perception was processed through auditory pathways and could be controlled by changing radiant energy.
A new strategy for boosting the performance of layer-by-layer organic photovoltaics (LOPVs) has been developed by incorporating a high-mobility crystallinity material into the acceptor layer. This approach achieved a power conversion efficiency (PCE) of 19.81%.
A comprehensive review introduces a pioneering exergy-based loss function for Physics-Informed Neural Network-Digital Twins, promising real-time optimization and accurate prediction of complex thermal systems. The study provides a definitive roadmap for industries seeking to minimize energy consumption while maximizing output in the In...
University of Oregon researchers engineer molecules and control regenerative cue release to improve healing outcomes for complex injuries. A staggered sequence approach shows better blood vessel regeneration, and the method is being applied to bone healing, muscle repair, and spinal cord regeneration.
A new drug, daraxonrasib, has been identified as a potential treatment for patients with NRAS-driven melanoma. The therapy targets and inhibits RAS protein, which drives cancer growth when mutated. Early results from preclinical models suggest the drug may be effective in treating advanced disease.
Researchers argue that EU and UK wildlife protection frameworks are fragmented, selective, and exception-based, threatening biodiversity. The authors propose strengthening laws to recognize animal sentience and introducing 'ethical continuity' into the legal framework.
Researchers at Wayne State University and Indiana University have developed a new class of drugs that target the Ku70/80 DNA-binding complex, a critical enzyme in DNA damage response. This approach aims to sensitize cancer cells to radiation and improve radiotherapy outcomes for lung cancer patients.
A study by Nooshin L. Warren found that small changes in sexual misconduct and gender portrayals can affect box office revenue, with adjustments adding or subtracting $8-13 million. Meanwhile, public expectations of gender roles seemed to regress after #MeToo, indicating a slower adoption of new norms.
A recent study found that human activities are fundamentally altering the chemical makeup of local coral reefs, leading to decreased coral health and resilience. The research team discovered that 25 contaminants from agricultural, industrial, and pharmaceutical sources accumulated in the soft tissues of coral around Maui, Hawai‘i.
A new study reveals that forest-dominated rivers in China regulate nitrogen removal through a combination of microbial activity, water and sediment conditions, altitude, and land use. Denitrification was the dominant nitrogen-removal pathway, accounting for up to 95% of total measured nitrogen removal in winter.
Combined exposure to copper and glyphosate causes stronger stress responses in earthworms than individual contaminants. Biochar reduces these effects, improving soil habitability and reducing earthworm response to contamination.
Researchers at Baylor College of Medicine identified a vulnerability in triple-negative breast cancers with LIG1 loss and used it to develop a new therapy for chemotherapy-resistant TNBC tumors. A combination of olaparib and ceralasertib showed significant effectiveness in reducing tumor growth in animal models.
A novel biological pathway has been uncovered that can lead to seizures when disrupted, providing a new approach for improved diagnosis. The study identifies an association between defective genes and increased glutamatergic transmission, which can increase the risk of seizures.
A new study found that baseball players with high school track experience performed better at the professional level than those who specialized solely in baseball. The research suggests that track development skills like speed and explosiveness translate directly to success in baseball, particularly in base running and fielding.
A global study analyzed 16.5 million DNA sequences from 23 cities across five continents, revealing a clear distance-decay pattern for bacterial communities. The findings show that port size, wastewater discharge, geography, and maritime activity closely associate with the structure of bacterial communities worldwide.
A University at Buffalo study has identified a link between Canadian wildfire smoke and decreased bird sightings in New York State. Analyzing air quality data with birdwatching reports, researchers found that nearly half of the studied species were less likely to be observed when PM2.5 levels rose, including many migratory forest songb...
The Endocrine Society recommends a diagnosis of hypogonadism based on low testosterone levels and symptoms. Testosterone replacement therapy (TRT) can improve quality of life for men with appropriately diagnosed hypogonadism, but its long-term safety is uncertain. Standardized testing and monitoring are crucial to minimize risks.
The coalition aims to facilitate innovative use of NAM tools, closing the gap in regulatory adoption. Crown Bioscience brings expertise in patient-derived models and biomarker analysis to support standardization of NAMs for regulatory acceptance.
Researchers at UT MD Anderson Cancer Center have made significant progress in treating rare brain infections with a virus-specific T cell therapy, achieving an overall response rate of 56.8% in patients with progressive multifocal leukoencephalopathy (PML). The center also introduced a novel CAR T cell therapy for hard-to-treat kidney ...
Researchers at Texas Children's Hospital have uncovered a novel biological pathway that can lead to seizures when disrupted. This finding provides a new approach for improving genetic diagnosis and treatment for epilepsy cases with unknown origins. The study also reveals that specific combinations of defective genes can cause seizures,...
A recent study reveals that occupations with more women pay less due to inherent societal biases, contrary to previous assumptions. The research suggests that employers can combat biases by standardizing pay criteria based on education, experience, and other factors.
Researchers expand potential of using bacterial spores for chemical reactions, biofuel production, and pollutant breakdown. New proteins fused to spore coat enable storage under extreme conditions without refrigeration.
A study published in Cancer Research identified an immune pathway that promotes the progression of oral precancerous lesions into head and neck squamous cell carcinoma. The researchers found that targeting a key inflammation signal known as interleukin-1 alpha (IL-1α) could help restore immune surveillance and prevent high-risk lesions...
Dr. Kaja Falkenhain receives the Peter J. Reeds Early Career Investigator Award for her groundbreaking work on human nutrition and metabolism. Her research focuses on cardiometabolic health and glycemic control, highlighting the impact of nutritional exposures on energy expenditure.
A clinical trial showed semaglutide improved liver scarring in patients with advanced fatty liver disease and early-stage cirrhosis. Non-invasive blood tests reflected treatment-related improvements more clearly than liver biopsies, which could reduce reliance on invasive procedures.
Researchers at UCLA have demonstrated a way to integrate terahertz functions onto a single chip using quantum well structures, paving the way for compact and scalable systems. This breakthrough could enable practical and widespread use of terahertz technology in applications such as ultrafast wireless communication, security screening,...
A new study suggests venture capital is playing a significant role in driving innovation in radiology, particularly in medical devices and artificial intelligence. The study found $11.4 billion was invested across 646 companies between 2000-2023, with funding peaking in 2021.
A new study has identified two naturally occurring microRNAs, microRNA-15a and microRNA-16, which can significantly reduce the growth and protein synthesis of non-small cell lung cancer cells. This finding suggests that these microRNAs could serve as targets for therapies designed to slow cancer progression.
A University of Houston professor is using artificial intelligence to connect roadway crash data, identifying pavement conditions associated with elevated crash risk. The study assesses pavement structure, surface condition, road geometry and crash records, helping transportation agencies select candidate pavement-safety projects.
The widespread implementation of driverless truck technology in the US could reduce transportation costs by 35%, resulting in significant increases in total interstate trade value. The impact would vary across states, with specific regions exhibiting higher percentage increases in exports.
Current federal rules based on plant age and leaf count are ineffective in predicting biological traits of American ginseng. Replacing these rules with size-based limits could better protect the wild population and simplify regulations for harvesters and forest farmers.
Researchers at Tufts University have developed thread-based integrated circuits that can bend, coil, stretch and conform to the body's contours. These devices could track biomarkers or environmental conditions, providing insights for fitness, healthcare and recovery from injury or disease.
Research on Southwest Florida cyanobacterial blooms shows that airborne cyanobacterial toxins contain the neurotoxin 2,4-DAB, which is linked to Alzheimer's disease and ALS. The study suggests chronic low-level exposure through breathing may be a significant risk factor for these diseases.
Researchers analyzed phone data from Marshall Fire evacuees, finding they chose destinations based on social connections and community resemblance. Those with stronger social networks were more likely to return home over time.
Researchers at Oregon Health & Science University mapped six major conformations of a membrane protein related to learning, memory and fear behavior. The findings provide a blueprint for designing new drugs to inhibit this channel in cases of stroke.
The Lancet Haematology Commission reports on global female health challenges, focusing on hematologic health across multiple stages of life. The report outlines recommendations for improving outcomes, particularly for women with under-recognized, underdiagnosed, and stigmatized heavy menstrual bleeding.
New research suggests dropping standardized testing requirements can expand access to underrepresented groups but worsen academic merit assessments, especially for nontraditional applicants. The study found that removing the test score requirement can have nuanced effects on diversity and merit outcomes.
A new atlas has been developed to map the potential of genes in predicting adverse drug reactions, utilizing a comprehensive analysis of genetic data from the Million Veteran Program. This genomic-led strategy aims to anticipate drug safety effects by identifying key genetic variants associated with adverse reactions.
The OU College of Medicine has received a $10.7 million NIH grant to study how cells sense their environment and respond to diseases that occur when this process malfunctions.
Researchers at the University of Arizona have demonstrated a new application for graphene nanoribbons, a material that can withstand extreme environments. The team integrated GNRs into semiconductor devices and exposed them to gamma radiation, showing that they can serve as radiation sensors for fusion reactors and in deep space.
A portable, airpod-size fluorescence analytical device has been designed to provide timely home molecular testing. The VPodDuo can measure fluorescent signals generated by various detection chemistry formats and detect quantities of genetic material from several pathogens and human cancer markers.
The HIV/AIDS response program in Brazil has lost momentum as the social movement becomes depoliticized, with activists focusing on basic issues like access to food and housing. The study suggests that technological advances and medicalization of policies have contributed to this trend.
Researchers developed an advanced generative model called ALADYNOULLI to uncover underlying disease processes and predict individual outcomes. The model reduced complex patient histories into 21 reproducible 'latent' disease signatures, which were highly similar across datasets and reproduced known disease processes.
Researchers used PET imaging to find significantly lower muscarinic acetylcholine M1 receptor availability in schizophrenia patients compared to healthy individuals. This study provides the first in vivo evidence of widespread M1 receptor deficits in schizophrenia, supporting the development of muscarinic-based therapies.