Rock art discovered in northwest Arnhem Land reveals up to 14 new images of the Tasmanian tiger, challenging the theory that it became extinct around 3,000 years ago. The artwork, created using red ochre and white pipe clay, provides rare insight into the cultural importance of thylacines in everyday life.
Researchers discovered that even tiny amounts of PFDA cause visible facial changes and increase risk by 10% at low exposure levels. PFDA blocks key enzyme CYP26A1, disrupting retinoic acid metabolism and leading to abnormal facial development.
Early and continuous acoramidis treatment resulted in sustained incremental reductions in all-cause mortality, cardiovascular-related mortality, and first cardiovascular hospitalization. The findings support the importance of early and continuous long-term treatment with acoramidis in transthyretin amyloid cardiomyopathy.
A Mayo Clinic study found that AI-derived heart fat measurement can predict cardiovascular events more accurately when combined with traditional risk assessment approaches. The measurement significantly improved long-term risk prediction, especially among patients at low-risk categories.
A new study reveals that improving surrounding landscape quality can increase bird species survival in forest remnants, with modest increases in nearby tree cover substantially boosting numbers. This contradicts traditional views on habitat fragmentation and highlights the importance of a more hospitable matrix for conservation.
Researchers develop CAR T cells designed to target both cancer cells and supportive cells in the tumor microenvironment, bearing the surface protein uPAR. The new approach shows significant power to fight cancer with limited impact on other healthy tissues and cells.
Researchers at Osaka Metropolitan University identified the tegmentum region as the area where light signals from the eyes and pineal organ are integrated. This integration enables fish to swim up or down based on differences in light wavelength, aiding survival decisions.
Researchers at NIST have developed a new way to package photonic integrated circuits, allowing them to operate in extreme environments. The HCB technique creates an inorganic bond between the optical fiber and the photonic chip, enabling precise alignment and efficient light coupling.
A study found that elevation of artemin could serve as a disease marker and potential therapeutic target for osteoarthritis in cats. The researchers confirmed that TRP channels commonly associated with osteoarthritis pain were expressed and functional in healthy cat DRG neurons, and increased artemin blood concentrations were correlate...
A new study found that over 40% of children who experienced peer victimization showed clinically significant trauma symptoms. Researchers tracked 250 students' experiences with peer victimization and found that trauma-related symptoms persisted for more than six months.
Researchers developed a perovskite-type ceramic catalyst that maximizes ethanol-to-hydrogen conversion through exsolution of nickel nanoparticles. The study demonstrated the importance of calcination temperature in controlling catalyst performance.
A new study found that modern genetic testing can identify clinically significant genetic explanations for schizophrenia in about 6% of patients, or roughly 1 in 16 individuals. Early age of onset and co-occurring neurodevelopmental disorders are associated with a higher likelihood of finding a genetic explanation.
A large-scale computational study found that point-of-origin effects significantly influence protein diversification, with relatively small divergence seen from ancestral proteins. The research reinforces existing theories on initial protein formation and highlights the limitations of modern AI protein design methods.
A new AI-based system analyzing blood vessels at the back of the eye has been shown to identify people at risk of heart problems with strong correlation. The system, called CLAiR, received Breakthrough Device designation and demonstrates promise as a noninvasive screening method.
Researchers at UMass Amherst have made a breakthrough in shrinking the size of quantum computers by integrating laser systems onto photonic chips. This technology has the potential to enable large-scale quantum computing and make optical clocks portable, with applications in fields such as deep space navigation and GPS.
A recent study found that discontinuing beta-blockers in stable, low-risk patients who have had a heart attack is non-inferior to continuing them. The results suggest that lifelong beta-blockers may be unnecessary for some patients. Discontinuation was associated with similar outcomes and quality of life compared to continued therapy.
Researchers have developed copper-loaded starch nanoparticles that can be broken down by specific bacteria to release antibacterial copper molecules. These nanoparticles were effective against Staphylococcus aureus and Bacillus subtilis, with improved targeting capabilities compared to previous studies.
A team of researchers has created a 3D model of pediatric brain tumors using biopsy-derived organoids, allowing for more accurate testing of new drugs. The model, which accurately reproduces the human environment, preserves the molecular characteristics of the original tumor and maintains cellular heterogeneity.
Researchers have developed a highly sensitive electronic 'skin' using tiny devices that can measure force applied over an area. This technology has the potential to improve prosthetic limbs and robotic manipulation, allowing robots to accurately track hand movements and grasp delicate objects.
Researchers found a 38% higher risk of diabetes in adults with HIV who switched from protease inhibitors to integrase inhibitors. The study suggests that medication changes may have adverse metabolic impacts, warranting close monitoring, regardless of weight gain.
Two studies suggest that loneliness is not just a lack of connection, but how people experience those connections, with increased risk of disease and death associated with feelings of lonelier-than-objective isolation. Daily life perceptions of social threat also contribute to self-reinforcing sequences of emotional states, behaviors, ...
A study reveals dermcidin, a human body natural molecule, exhibits antiviral activity against the influenza virus. Higher baseline levels of dermcidin in individuals who don't develop flu-like symptoms may be associated with lower susceptibility to infection.
Researchers found that the ICM's mathematical predictions are due to a flaw in standardization and lack of evidence supporting inhibitory growth processes. The model was applied to non-sequential traits, contradicting its sequence-based development claim.
Researchers at University of Michigan Engineering and Michigan Medicine used protein nanoparticles to genetically modify several types of human cells, including liver cancer and immune cells. The goal is to develop a safer method for delivering gene therapies without using modified viruses.
Frangopol and his team develop a framework to optimize seismic retrofit strategies for deteriorating bridge columns, balancing risk and cost. The approach integrates time-dependent risk assessment, economic evaluation, and real options analysis to identify optimal intervention timing under uncertainty.
NRG Oncology has appointed Dr. John Nakayama as Vice Chair of the NRG Ancillary Projects Committee, Dr. Ibrahim Nassour as Vice Chair of the Surgical Oncology Committee, and Dr. Scott Okuno as Vice Chair of the Sarcoma Subcommittee. Dr. Angeles Alvarez Secord was also appointed Chair of the Investigator & Career Development Committee.
Researchers from UCSB and UMass Amherst successfully integrated stabilized laser chips with a room temperature trapped ion qubit, enabling compact and portable quantum systems. This breakthrough paves the way for applications in quantum sensing, computing, and fundamental science.
Researchers have designed a system that releases algaecide steadily over weeks or months, making it less expensive and more efficient than existing options. The buoys removed nearly all cyanobacteria without the need for frequent reapplication.
Researchers analyzed 48 isolates of P. griseola and found a potential symbiotic relationship between the fungus and endophytic bacterium Achromobacter xylosoxidans, influencing disease severity. The study sheds light on how the pathogen evolves and may point to new strategies for breeding disease-resistant crops.
Researchers have discovered how a disease-causing bacterium uses a single protein to interfere with the body's defenses in multiple ways, offering a clearer picture of how infections take hold at the cellular level. This discovery highlights the importance of targeting specific interactions between bacterial proteins and human cells in...
A study calls for increased coral assisted evolution research to help reefs cope with rapidly warming oceans. The international team identified nine research priorities, including expanding large-scale field-based research and long-term funding to understand coral biology.
The collaboration aims to improve manufacturing of silicon carbide ceramics, a strong material that can withstand high heat and radiation. Researchers will combine 3D printing and digital technologies to enhance production efficiency and reduce defects.
Researchers have developed a reconfigurable textile interface that supports flat touch, folded 3D manipulation, and shape-change commands. The 'one cloth, many states' framework reduces the need to swap props and recalibrate alignment, making it promising for constrained-space operation training and human-machine interaction scenarios.
Researchers develop ISAMFP, a computational framework that leverages natural target motion to enable super-resolution imaging of dynamic non-cooperative targets. By exploiting angular diversity and phase modulation, the method achieves high-frequency information recovery from sub-aperture intensity measurements.
Researchers have found that targeted ultrasound can aid in unlearning fear more efficiently by stimulating the amygdala, a key region in processing emotions. Participants who received ultrasound stimulation showed reduced fear responses to previously frightening stimuli.
A research team discovered that a protein complex consisting of SMG1, SMG8, and SMG9 ensures the efficient execution of nonsense-mediated mRNA decay (NMD). The study found that this complex is essential for maintaining the stability of NMD under various conditions.
A new systematic review found that screen time use among children and adolescents has dramatically risen over the past three decades, with a clear increase occurring after the onset of the COVID-19 pandemic. The review analyzed 60 peer-reviewed studies and found that older children and adolescents reported higher screen time than young...
A study published by HKUMed found that Resmetirom, a drug approved for treating metabolic dysfunction-associated fatty liver disease, demonstrates potential in preventing and suppressing liver cancer caused by fatty liver disease. The treatment also reduces liver fat, improves metabolic health, and modulates the tumour microenvironment.
Researchers at Tohoku University developed a method to transform regular surfaces into keyboards for AR/MR technology, using the blanching phenomenon to detect fingertip contact. The system requires no special sensors or devices and allows users to rest their fingers on the surface during operation, promoting comfortable interaction.
Scientists have discovered that a fast-rising strep bacterium comes in more forms than expected, with distinct variants linked to specific types of infections. The study provides critical genetic data to improve diagnosis, infection control, and future vaccine planning for this growing bacterial threat.
The new study introduces a comprehensive framework for conducting umbrella reviews in education, providing a structured and accessible guide for researchers. The study's findings highlight the potential of this method to provide high-quality evidence syntheses and strengthen educational research.
Researchers identified a bacterium strongly linked to noma, a deadly disease that affects young children in extreme poverty. Early detection through diagnostic tools could save lives and prevent severe disfigurement.
A study found that dentists have a higher prevalence of vision-related problems due to prolonged exposure to artificial lighting. Chronic dental lighting caused retinal damage, disruption of the blood-retinal barrier, and inflammation, ultimately impairing visual health.
Research in mice reveals direct gene regulation by alcohol metabolites, with varying effects on brain regions and exposure durations. Short-term exposure influences more genes and epigenetic programs compared to lengthy exposure.
Research using high-density EEG recordings found that infant brain activity changes rapidly between 3-6 months, reflecting synaptic connection growth and neural network maturation. This study provides a new method for early diagnosis of neuropsychiatric conditions.
Boehringer Ingelheim and EMFRET Analytics have partnered to advance the GPVI-blocking antibody EMA601 for acute stroke treatment. The substance targets platelet surface receptor glycoprotein VI, blocking thrombosis and inflammation while preserving normal blood coagulation.
The report, prepared by BioAgora, highlights the benefits of building-integrated greenery for biodiversity, climate resilience, energy efficiency, and human wellbeing. It offers actionable guidance for local authorities to integrate green roofs and walls into spatial planning and building codes.
A new policy brief from the University of Bonn and Vodafone Institute highlights Europe's hidden trade deficits with the US and China, which threaten its digital autonomy. The study advises strengthening manufacturing industry competitiveness and reducing dependence on China for digital goods.
Burst stimulation effectively mitigates decline in turning response decay, preserving stable frequency-response relationship and improving closed-loop locomotion control. The proposed navigation system achieves reliable path following with a success rate of 73% and average tracking error of approximately 12 mm.
Family physicians experiencing burnout are more likely to change practices or stop practicing entirely, with 43.5% reporting burnout in a recent study. This can lead to poorer patient outcomes, including increased ER visits and lower care satisfaction.
A global meta-analysis of animal activity found that wildlife shapes landscapes through everyday activities like burrowing and feeding. The study revealed a significant influence on geomorphic processes, with animal activity altering the porosity of soils and sediments by up to 136% in freshwater ecosystems.
The programme aims to nurture youth engagement in marine conservation and strengthen Hong Kong's environmental stewardship by providing hands-on training and empowering students as the next generation of ocean stewards. Students gain experience with advanced research techniques and build leadership and advocacy skills.
A sociologist's research focuses on personal stories behind assisted death decisions, challenging the assumption that choosing death is a rational decision. The study introduces concepts like biographical contraction and closure to understand the complex process of end-of-life choices.
A new study from the University of Oulu suggests that large swings in bedtime could double the risk of serious cardiac events. Inconsistent bedtimes were strongly associated with a higher risk of major cardiovascular events, especially among those who get less than eight hours of sleep.
A new study by UNSW Sydney and published in Carcinogenesis suggests that nicotine-based vapes are likely to cause cancers of the lung and oral cavity. The research, led by Adjunct Professor Bernard Stewart AM, analyzed global research and found consistent findings across multiple disciplines.
Researchers at the University of Bristol found that gentle human interactions trigger positive emotions in young chickens. The study's results suggest that early-life handling can shape animals' affective experiences and improve their welfare.
A study by IBEC reveals how thousands of amylin mutations influence its tendency to form toxic aggregates in the pancreas, linked to type 2 diabetes. The researchers created a mutational map using deep mutational scanning, identifying variations that promote or hinder amyloid formation.
The BD² Integrated Network Longitudinal Cohort Study combines clinical, biological, neuroimaging, and real-world behavioral data to transform understanding of bipolar disorder. The release includes data from 615 participants, covering mood, cognition, brain structure, wearable sensor data, and biological samples.
A new study from Boston University School of Medicine has discovered distinct blood metabolite patterns in centenarians that diverge from typical age trends. The findings suggest unique higher levels of certain primary and secondary bile acids and preserved levels of several steroids, linked to lower death risk. These metabolic signatu...
A new study found that parental academic pressure is linked to four distinct forms of motivational cost: effort, opportunity, psychological, and emotional. These costs are associated with school burnout and academic achievement, but not in the same way.