Researchers have found that screening for early-stage type 1 diabetes in children can be implemented sustainably in general pediatric practice, identifying most children who will later develop stage 3 clinical type 1 diabetes. The study suggests that families without a family history of the disease should also be screened.
A new Ohio State University study aims to raise awareness of the link between alcohol consumption and breast cancer risk among young women. The study uses targeted messages to educate participants about the risks and encourage reduced drinking habits.
A recent study found that social living is associated with longer lifespan in mammals, but the benefits of group-living level off after pairs. The researchers analyzed life-history traits and body mass, finding that both pair- and group-living species live longer than solitary ones.
A new preclinical study suggests that targeting tumor-specific inflammatory processes could enhance the efficacy of some anticancer therapies and prevent drug resistance. The researchers found that tumors treated with KRAS inhibitors often developed inflammation-related gene expression changes, which contributed to drug resistance.
A study by EHU researchers found that exercising outdoors can help combat vitamin D deficiency and strengthen the immune system. The study suggests that taking vitamin D supplements has no direct effect on physical performance, contrary to popular belief.
Researchers at the University of Malaga demonstrate that organic farming enriches specific groups of soil microorganisms, particularly bacteria from the genus Bacillus, which help plants cope with drought. This sustainable agricultural management system can lead to more resilient crops in dry areas and reduce fertilizer use.
Scientists at OIST create well-ordered antiferromagnetic crystal with controlled chemical disorder, tracking evolution from order to disorder. They clarify the definition of spin glass, offering a new baseline for studying exotic materials.
Research finds gestational diabetes significantly increases risk of type 2 diabetes in women with normal pre-pregnancy weight. The study, published in eClinicalMedicine, analyzed over 1.15 million Swedish mothers and found elevated blood sugar levels predict future type 2 diabetes.
A long-term study identifies dozens of previously overlooked cultural behaviors in wild chimpanzees, doubling previous estimates. Chimpanzees learn basic skills like foraging and grooming through social learning, with a focus on identifying and processing food, suggesting that cultural transmission plays a key role in their development.
A new EdUHK study shows that adolescents with lower digital literacy levels are more vulnerable to cyberbullying. Those who develop stronger digital literacy skills after experiencing cyberbullying tend to navigate threats and protect themselves effectively.
A new study reveals that nitrosylcobalamin, a vitamin B12 analog, selectively crosses the blood-brain barrier and targets glioblastoma tissue, demonstrating broad antitumor activity. The therapy also shows synergistic activity with existing treatments, offering a promising new strategy for treating this deadly brain cancer.
Researchers have discovered that precursor lesions in the pancreas, often considered a step towards cancer, do not undergo malignant transformation if they lack a specific microenvironment. The team used advanced technologies to isolate and analyze single cells from over 150 donated pancreases, finding that the microenvironment surroun...
Researchers developed a new eye drop treatment that significantly reduced dry eye disease characteristics, such as inflammation and loss of goblet cells. The treatment uses a rexinoid compound that boosts the protective role of resident macrophages, promoting debris-clearing and immune balance.
A recent study by WSU researchers reveals nearly 30% of rodents in the Palouse region showed evidence of past infection with Sin Nombre virus, a deadly respiratory disease. The study also produced the first full genome sequences of SNV strains from the Northwest, highlighting high genetic diversity and viral reassortment.
Researchers developed a new 9-question test to evaluate preschool children's social skills. The test was found to be stable and reliable, with correlations between teachers' assessments being good.
A nationally representative survey of empaneled adults found that most Americans understand how STIs spread, but there are significant gaps in public knowledge about which infections can be prevented through vaccination. The survey also revealed strong awareness of common transmission pathways and some basic facts about STIs.
Researchers developed an optimized extended precision cut liver slice (PCLS) culture system maintaining viable human liver tissue for up to two weeks. The model captures regeneration, fibrosis, and biliary remodeling in intact human liver tissue.
A study by Norwegian University of Science and Technology found that private health insurance uptake is linked to poorer health in the population, particularly among those with low education levels. The researchers suggest that policymakers should implement strategies to mitigate this negative effect.
The new edition of the Wiley Registry of Mass Spectral Data 2026 expands compound coverage to over 915,500 reference spectra, strengthening a foundational layer of scientific data and research intelligence. This expansion enables researchers to identify unknown chemical compounds and materials faster with confidence.
Binghamton University has achieved a gold star rating through the Association for the Advancement of Sustainability's STARS program. The university excelled in research, public engagement, and coordination and planning, with notable initiatives including smart energy research and environmental justice efforts.
A machine-learning guided lifestyle coaching program based on data collected via personal devices reduced depressive symptoms by six weeks. Participants who implemented the program experienced significant reductions in depressive symptoms and the treatment effect persisted during three months after the intervention ended.
Researchers have developed a single device that can harvest light and emit bright visible light, achieving high efficiency in both power conversion and electroluminescence. The device uses a novel organic semiconductor material with controlled energy flow, enabling it to operate at standard lithium-ion battery voltages.
Researchers identified a vitamin K-dependent GAS6 pathway that controls osteoclast maturation and bone resorption in mice. Osteoblasts use Vitamin K signals to regulate osteoclast fusion via the GAS6 pathway.
A new study maps how 29 factors influence one another in young adults aged 18-40, revealing self-reinforcing loops that worsen depressive symptoms and disrupt sleep. The model highlights the complexity of these interactions and suggests a nuanced approach to breaking the cycles.
The 2025 Impact Report showcases tangible progress made by CURE SYNGAP1, including almost $1.8M in grants and the most successful SYNGAP1 Science Conference ever. The report highlights the organization's focus on Collaboration, Transparency, and Urgency, driving momentum for clinical trials and treatments.
Researchers found that structured lifestyle programs with coaching and accountability can reduce frailty in older adults by promoting healthy habits. The two-year US POINTER trial showed significant improvements in overall health and frailty scores among participants who followed the structured program.
The Restore-1 clinical trial aims to modify the small intestine's lining with steam energy to restore natural blood-sugar control in patients with type 2 diabetes. The procedure, if successful, could prevent patients from advancing to insulin-dependent diabetes.
A new study finds that investing in cleaner alternatives for the steel sector before 2030 can prevent 73 gigatonnes of CO2 emissions by 2070. This would be more cost-efficient than reducing emissions through other sectors or carbon removals.
Researchers found that atoms on certain gold surfaces naturally rearrange themselves into protective patterns that suppress reactions with oxygen. This discovery helps explain why gold jewelry and objects can remain untarnished for centuries.
Researchers identified a key protein called PERM1 that is restored in patients whose hearts recover after left ventricular assist device (LVAD) support. PERM1 regulates energy production and contractile function in heart cells, and its normalization is associated with improved cardiac function.
Professor Hannah Cloke's appointment as Regius Professor of Meteorology and Climate highlights the importance of human imagination in understanding and mitigating extreme weather. Her research has already helped communities prepare for floods and extreme weather, and she aims to empower people to take charge of their own futures.
A new study of over 1 million young Swedish men found that the risk of atrial fibrillation is less than previously calculated, and the benefits of high fitness levels outweigh the risks. After age 40, the balance shifts in favor of higher fitness levels, suggesting that the benefits of exercise may be more significant.
Researchers have created a gene expression map of seed development in Arabidopsis thaliana, revealing the role of specific genes and cell types in shaping seed traits. The study identifies key regions where hormones regulate growth and nutrient storage, providing insights into how seeds develop and can be improved for crop productivity.
A new study replicated patient- and sex-specific hallmarks of Inflammatory Bowel Disease (IBD) in a human organ chip, identifying stromal fibroblasts as key drivers of inflammation, fibrosis, and enhanced cancer risk. The model also recapitulated the impact of pregnancy hormones on IBD severity in female patients.
A new study highlights the potential of AI tools in soil science, enabling researchers to better understand soil ecosystems and adapt to climate change. The system successfully generated hypotheses on how soils store carbon and what controls their storage limits, with outputs aligning with expert research.
New AI tools can accelerate soil science by speeding up early-stage work, improving predictions to support decisions on land-use, carbon, and climate adaptation. The system successfully mimicked key parts of the scientific process, with outputs beyond what's currently being used that strongly align with expert research.
Researchers from EPFL have developed a new holographic approach to volumetric 3D printing, enabling cell-compatible, high-resolution printing at near-clinical scales. The method uses phase control to produce higher-fidelity objects in light-scattering media, such as those containing living cells.
A new study found irisin reduces clinical symptoms and neuron loss in a mouse model of MS. Irisin also protects neurons from inflammation-driven neurodegeneration.
Researchers developed an AI system called CMR-CLIP that can interpret complex heart scans without manual labels, outperforming existing models by up to 35%. The system learned from over a million images and hundreds of thousands of motion sequences collected from Cleveland Clinic.
A team from Graz University of Technology has developed a prefabricated brick wall system that can be dismantled and re-used without being destroyed. The system reduces CO2 emissions by up to 60% compared to conventional construction methods, offering significant environmental benefits.
Researchers at ISTA uncovered why keratin plays an essential part in embryonic cell movement and organization. Without keratin, the process slows dramatically, leading to tissue collapse and loss of cellular alignment. Keratin helps maintain the structural integrity and cohesion of cells during early development.
Europe's bacterial STI cases reached record highs in 2024, driven by gonorrhoea and syphilis, with men who have sex with men disproportionately affected. The near doubling of congenital syphilis cases highlights the need for improved antenatal screening protocols to prevent transmission to newborns.
A study analyzed over 300,000 citizen science observations to identify patterns influencing participation rates. Regional data from the Hungarian Central Statistical Office was combined with citizen science data to examine the relationship between socio-economic and environmental factors on observation density.
Researchers from OIST have reported the first full structural characterization of a doubly ring-slipped reaction intermediate in metallocene formation. This discovery provides new evidence on how metallocenes form and react, presenting opportunities for designing tunable structures for applications such as drug delivery systems, cataly...
A lower CA19-9 cutoff of 7 units/mL can identify patients with pancreatic cancer who have high-risk disease despite low biomarker levels. This dual-threshold model helps distinguish between true low tumor burden and Lewis antigen-negative status, improving prognostic assessment.
Researchers at Cornell University have developed a robotic collective that exhibits coordinated motion and adaptability without centralized control. The Cross-Link Collective consists of small robots that can entangle and move collectively, self-organizing into shifting configurations.
A new study found that air pollution can disrupt insect communication by chemically altering pheromones. Ozone pollution degrades pheromone signals in moths, reducing mating success and threatening pheromone-based pest control strategies.
Researchers at the University of Guelph developed a faster way to identify potential drug targets against Candida albicans using CRISPR interference. The new system reduced the time from laboratory discoveries to clinical applications by years, focusing on hundreds or thousands of genes simultaneously.
Tahiyat Rahman, a physics Ph.D. holder, will work on policy investing in workforce and training for quantum technologies and materials manufacturing. As a Congressional Fellow, they aim to build public consensus around science policy.
Research shows that intrinsic motivations, such as enjoying physical activity and feeling healthy, consistently matter most in predicting aerobic fitness. Teenagers who value these factors are significantly fitter at 17 than those motivated primarily by winning or external rewards.
New research from the University of Otago has uncovered a specific biomarker in blood plasma associated with Alzheimer's disease. The study found that elevated levels of ptau181 were linked to subjective cognitive concerns, but not objective decline or structural brain integrity measures.
Researchers used cryo-EM to investigate the molecular basis of functional diversity in alcohol oxidase isozymes. The study found structural differences in cofactor binding and amino acid residues that affect enzyme stability and catalytic performance, ultimately resulting in distinct roles among the variants.
Researchers developed Cel-T plastic, a novel cellulose-based supramolecular plastic with high mechanical strength, thermal stability, and versatile shapeability. The material combines the strengths of polylactic acid, polymethyl methacrylate, acrylonitrile-butadiene-styrene, and polyethylene terephthalate.
CURE SYNGAP1 partners with RARE-X to accelerate ProMMiS study's Patient-Reported Outcome measure data collection. This investment enables the centralized collection of high-quality PROs, essential for regulatory approval and therapy development.
The Lancet MedZero platform offers product-level carbon data for hospitals and health systems worldwide, enabling evidence-based decision-making and supporting climate action. With over 14,000 entries launched, the platform aims to help healthcare institutions reduce waste, improve patient care, and tackle climate change.
Researchers identified CREP1, a pectinase-like effector protein from Fusarium lateritium, as a key regulator of plant immunity. CREP1 interacts with receptor protein NbEIX2 to activate immune responses, including ROS burst and cell death.
Research identifies a novel narnavirus, TmNV1, as a potent virulence attenuator in Talaromyces marneffei. Coinfection with TmPV1 amplifies hypovirulent phenotypes, reducing fungal burden and inflammation.
Researchers from The University of Osaka discovered that only a small proportion of CD8 T cells undergo sustained clonal expansion in multiple myeloma immunotherapy, leading to the strongest anti-tumor response. Early immune activity could help predict which cells will become effective cancer fighters.
Recent advancements in microwave dielectric ceramics research focus on property characterization, theoretical mechanisms, sample preparation, applications, and data-driven discovery. Key findings include the development of standardized resonant methods for evaluating low-loss materials and advanced cold sintering processes enabling co-...
A new study from Edith Cowan University found that music listening habits vary greatly among university students. For some, music boosts motivation and enhances focus, while others find it distracting. The research highlights the importance of individual differences in music engagement in studying.