Research in Canadian Medical Association Journal found that babies born to mothers with endometriosis are at a higher risk of congenital anomalies. The study included over 1.4 million births and found an increased risk of cardiovascular, gastrointestinal, genital, and musculoskeletal anomalies as well as neoplasms and tumours.
Researchers found that glutamic acid induces two transcriptional repressors, StbZIP53-like2 and StERF091, which suppress polyphenol oxidase genes linked to browning. This cooperative regulatory module alleviates browning in fresh-cut potatoes.
This innovative material combines the mechanical flexibility of an organic hydrogel with exceptional microwave absorption properties. The synergy between MXene and carbon dots provides a powerful tool for managing electromagnetic pollution in wearable electronics.
Researchers have developed an electrochemical route to produce hydrogen peroxide directly from oxygen and water under ambient conditions. Single-atom electrocatalysts play a crucial role in steering oxygen reduction chemistry towards the desired two-electron pathway.
Researchers develop hemoglobin-based nanoparticles to deliver tigecycline directly to Klebsiella pneumoniae infection sites, improving survival rates and reducing bacterial burden. The novel strategy overcomes dose-limiting toxicity and enhances pharmacokinetics of the antibiotic.
The HF-REVERT trial found that CDR132L improved secondary endpoints, including LVEF and NT-proBNP, but not the primary endpoint of LVESVI. Target engagement was confirmed by decreased plasma levels of microRNA-132. The therapy was well-tolerated with no significant safety concerns.
The summit brought together endocrine leaders to identify opportunities to work closely together on increasing the visibility of endocrine health in policy decisions. Early findings from a workforce survey revealed challenges including long patient waiting times and retention concerns among early-career clinicians.
Researchers found that low-dose digoxin and digitoxin reduced worsening heart failure events in patients with mild-to-moderate heart failure and reduced ejection fraction. The treatment was generally well-tolerated and safe, offering a cheap and effective option for managing the condition.
The APOE2 gene variant is linked to exceptional longevity and reduced Alzheimer's risk, thanks to its ability to help human neurons keep their DNA intact and resist cellular senescence. This study reveals a previously underappreciated function of the gene, shifting attention away from its role in cholesterol transport.
A new international study found that genetic variations in the PAM gene can reduce the effectiveness of GLP-1 receptor medications, such as Ozempic. Researchers discovered that 44% of people with these genetic variants experienced reduced glucose lowering properties, and only 11% achieved recommended glucose levels.
The study introduces a triboelectric-driven framework that unifies visual, tactile, auditory, olfactory, and gustatory inputs within a self-powered architecture. The system demonstrates high-accuracy cross-modal recognition and adaptive sensory reconfiguration, offering a new pathway toward energy-autonomous robotic cognition.
Researchers develop a light-driven antenna-reactor photocatalyst that achieves highly efficient alkyne semihydrogenation under ambient conditions. The system promotes efficient hydrogen dissociation while steering the reaction toward selective semihydrogenation, enabling near-complete conversion with excellent selectivity.
The 'Ozempic Era' suggests a paradigm shift in understanding obesity, blaming commercial food systems rather than individual failings. Emerging medical data on GLP-1 agonists may drive policy responses to regulate ultra-processed foods.
A new study found that reducing annual working hours by 1% is linked to a small decline in obesity rates across 33 OECD countries, with the impact being stronger for men than women. Higher income levels and urbanization also showed significant correlations with lower obesity prevalence.
A pooled analysis of trials reveals semaglutide's safety and efficacy in individuals aged 65 years and older with obesity. The study found significant reductions in body weight and improvements in cardiometabolic risk factors, with a lower proportion of adverse events compared to placebo.
A new post-hoc analysis examined daily oral orforglipron treatment for obesity, with or without diabetes, in users aged 65 years and over. The study found that orforglipron significantly reduced body weight and improved blood sugar markers compared to placebo, with a similar safety profile to the overall ATTAIN clinical trial population.
A study of 65 countries found that consuming food away from home is consistently associated with obesity. Eating out is driven by sociodemographic factors such as sex, age, income, and education, and is linked to higher energy intake and body mass index.
Researchers have mapped the structure and mechanics of a critical cellular machine that malfunctions in people with rare genetic disorders. The discovery could lead to new treatments and faster diagnoses for children with conditions like infantile encephalopathy, corpus callosum hypoplasia, and Kenny-Caffey syndrome.
A new study reveals Antarctica's sea ice collapse is driven by a triple whammy of climate chaos, resulting in record-breaking lows. The Southern Ocean's transformation led to the loss of vast areas of ice equivalent to Greenland, destabilizing global ocean currents and accelerating global warming.
Researchers have discovered that plants utilize two forms of cyclic adenosine monophosphate (cAMP) to regulate normal cellular functions and respond to stress, while maintaining cross-talk between the pathways. This redundancy enables plants to adapt more robustly to a wider range of environmental factors.
Pompeu Fabra University has awarded the title of Doctor Honoris Causa to Helga Nowotny and Maria Leptin for their contributions to consolidating a European research model. The award highlights the importance of fundamental research, interdisciplinarity, and scientific independence in achieving European values.
The book captures the AI moment through a chorus of perspectives from science, business, art, journalism, and media, challenging and complementing each other to reveal tensions and contradictions. It paints a vivid picture of how AI is reshaping our self-understanding and what it discloses about us.
A new study found that nearly every person in the US has multiple man-made chemicals, known as PFAS, in their system. The study examined over 10,500 samples and found that 98.8% contained at least one PFAS, with many carrying multiple types.
Scientists have successfully demonstrated atomic spin qubit interaction with a single-quantum sound wave, opening up new possibilities for quantum information storage and sensing applications. The experiment uses phonons to interact with atomic defects in diamond, enabling precise measurement of forces and temperatures.
Researchers developed a deep learning method that optimizes both material layout and fiber direction for continuous fiber composite structures, reducing design time by up to 99.7% while maintaining strong accuracy. The ResUNet-GAN framework produces high-performance structural layouts directly from design parameters.
Researchers develop irreversible CRISPR base editing system to permanently block microbial survival, reducing environmental risk and genetic instability. The technology has broad applications in industrial biotechnology and biopharmaceutical fields.
A research team has successfully removed the primary obstacle to post-silicon computing by creating a record-breaking electronic connection for atomic-thin materials. The new GaOx layer enables 'hybrid tunnelling' mechanism, reducing contact resistance and allowing transistors to operate at much lower voltages without sacrificing speed.
A new photocatalyst was developed that can efficiently reduce nitrate, CO₂, and water under visible light. The catalyst achieved high reductions in efficiency, with selectivities for nitrogen gas, methane, and hydrogen reaching 80%, 70%, and 60%, respectively.
Researchers at Seoul National University developed a new mechanical system that amplifies motion and remembers external triggers through magnetic attraction and elastic restoring force. The system, called Elasto-Magnetic Instability (EsMI), enables large-amplitude vibration and efficient energy conversion.
Researchers present a comprehensive numerical simulation of atmospheric pressure non-equilibrium plasma discharge in CO₂–H₂O plasmas. The study reveals dominant reaction pathways, including electron-impact dissociation and ionization, which affect streamer dynamics and reaction pathways.
Researchers identify three major bottlenecks: multiscale modeling complexity, operational multi-stability, and scale-up difficulties in autothermal reactors for CO₂ hydrogenation to methanol. This mismatch can produce multiple operating regimes, making temperature control challenging.
A clinical trial found that adding molecular tests on urine and stool samples did not speed up treatment initiation or reduce mortality in hospitalized patients with HIV. The study showed no significant difference in treatment initiation within 72 hours between the expanded screening group and the standard group.
The SNU research team created an LCE-based artificial muscle that integrates sensing and actuation functions, mimicking biological muscle-tendon complexes. This breakthrough technology enables robots to delicately manipulate objects and recognize their properties.