About The Study: In contrast to earlier studies, this meta-analysis found significantly higher treatment failure and major complication rates within a year with nonoperative management among children and adolescents. The meta-analysis provides pediatricians and pediatric surgeons with up-to-date data to inform shared decision-making with families and encourage individualized, patient-centered treatment.
Corresponding Author: To contact the corresponding author, Isabella Faria, MD, email imdefrei@utmb.edu .
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(doi:10.1001/jamapediatrics.2025.4091)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented at the American College of Surgeons Clinical Congress 2025.
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JAMA Pediatrics