About The Study: In this multicenter randomized clinical trial, a nontargeted screening approach was superior to targeted screening for identifying new hepatitis C virus infections among patients seen in 3 urban emergency departments. The substantial decrease in patients who went from diagnosis to sustained virologic response at 12 weeks highlights an urgent need for innovative models of hepatitis C virus treatment.
Corresponding Author: To contact the corresponding author, Jason Haukoos, MD, MSc, email jason.haukoos@dhha.org .
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(doi:10.1001/jama.2025.10563)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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