About The Study: Treatment-emergent nirmatrelvir resistance mutations were commonly detected, especially in individuals who were immunosuppressed in this cohort study of 156 participants. However, these mutations were generally present at low frequencies and were transient in nature, suggesting a low risk for the spread of nirmatrelvir resistance in the community with the current variants and drug usage patterns.
Corresponding Author: To contact the corresponding author, Jonathan Z. Li, MD, MMsc, email jli@bwh.harvard.edu .
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(doi:10.1001/jamanetworkopen.2024.35431)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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