A team of researchers used computational analysis to identify a new therapeutic strategy for treating drug-resistant breast cancer. The study found that disrupting glucose metabolism is an effective approach, targeting existing drugs like Lapatinib. This discovery may offer improved treatments for breast cancer patients.
Jiri Friml received the EMBO Gold Medal for his groundbreaking research on auxin transport and gradient formation in plants, which has significant implications for plant development and agriculture. His work provides a basis for targeted engineering to develop plants that produce higher yields or are more resistant to drought.
Researchers have identified a naturally occurring protein involved in generating chronic pain in rats, which could lead to new therapeutic treatments. The discovery highlights the impact of molecular signalling events on nerve transmission and offers promising avenues for pain relief.
A special issue of the EMBO Journal marks three decades of Wnt/beta-catenin signaling research, revealing its crucial role in development and human disease. The pathway's importance is also highlighted in cancer biology.
EMBO welcomed 55 new members, including 13 female scientists, representing a broad cross-section of life sciences. The selected researchers will contribute to the direction of life sciences in Europe and beyond through their involvement with EMBO activities.
Researchers identify hormone Dilp8 as key player in regulating insect growth, ensuring proper body size and proportions. The protein helps slow down tissue growth, allowing organs to develop correctly and maintain symmetry.
The TARA OCEANS expedition mapped marine biodiversity across the world's oceans, understanding how microscopic organisms interact with their environment. The project aims to build a global systems biology map of these interactions, using advanced DNA sequencing and microscopy techniques.
Susan M. Gasser has been recognized for her outstanding scientific research on genome stability and epigenetics, as well as her commitment to mentoring women in science. She has made significant contributions to our understanding of chromatin biology and epigenetics, with implications for human disease, including cancer.
Matthias Mann's work on mass spectrometry revolutionized the analysis of proteins, enabling quantitative analysis of cancerous tumors. Fiona Powrie's research on bacterial intestinal flora and immune system interactions opens new perspectives for treating chronic inflammatory diseases.
EMBO has selected 22 young researchers for its prestigious Young Investigator Programme, aiming to support their promising careers. The programme provides funding, networking opportunities, and mentorship to help them advance their research.
Boulton's research highlights include discovering key genes and enzymes involved in DNA repair mechanisms, including RTEL1 and ALC1. His work has led to novel therapeutic approaches for cancer treatment, particularly liver cancer.
Carol V. Robinson has pioneered the use of electrospray mass spectrometry for structural studies of large protein assemblies. Her research has opened up a new area of mass spectrometry and inspired future generations of women in science.
Stefan Jentsch receives prize for discovery of ubiquitin's role in genome maintenance and DNA repair, while Edvard and May-Britt Moser win for grid cells discovery that enables spatial navigation and memory.
Six scientists from Croatia, Czech Republic, Poland, Portugal, and Turkey will receive the 2010 EMBO Installation Grants for 3 years. They will be integrated into the prestigious EMBO Young Investigator programme with networking opportunities and career development programmes.
The EMBO Young Investigator Programme has selected 21 talented young researchers from across Europe to join the network. These group leaders will receive financial support and benefits such as lab management training and networking events.
The European Molecular Biology Organization (EMBO) has recognized 63 life scientists for their outstanding research contributions. Among the new members are 12 female researchers who have made significant advancements in various fields of molecular biology, neuroscience, and cancer biology.
Jason W. Chin receives the EMBO Gold Medal for his groundbreaking work on reprogramming the genetic code, allowing molecular biologists to control and elucidate protein functions with unprecedented precision. His research enables the creation of designer amino acids, opening doors to new applications in protein therapeutics and materials.
Ingrid Grummt, a renowned geneticist, has been awarded the 2010 FEBS/EMBO Women in Science Award for her groundbreaking work on transcriptional regulation. The award recognizes not only her scientific achievements but also her commitment to mentoring and inspiring future generations of women in science.
EMBO has awarded 50,000 euro grants to 5 scientists to establish research groups in the Czech Republic, Poland, and Portugal. The grantees will join the prestigious network of EMBO Young Investigators and integrate into the European scientific community.
The EMBO Young Investigators Programme identifies top European young life scientists, offering academic and financial help to set up independent research labs. The selected 17 young group leaders work in nine countries, with an average age of 36 and four women, and will benefit from various activities including mentorship and networking.
EMBO has elected 66 top-life scientists with expertise in various molecular biology fields, including evolutionary and computational biology. The new members come from 16 countries and include 15 female researchers recognized for their contributions to life science research.
The EMBO organization has introduced a new private pension plan for its fellows, providing a benefit package tailored to the needs of highly mobile scientists. The plan allows contributors to continue in the plan as they move from country to country, offering flexibility and portability.
Lars Jansen, a young researcher from the Instituto Gulbenkian de Ciência, has been awarded an EMBO Installation Grant to establish a new research group in Portugal. The grant provides funding and support to help him develop his research infrastructures and integrate into the European scientific community.
Olivier Voinnet's groundbreaking research on gene silencing via RNA has opened new perspectives on controlling gene activity, with implications for medicine and genome integrity. His work has also shed light on the molecular arms race between hosts and parasites.
Anne Houdusse's work has established the molecular structure and function of myosins, a family of vital motor proteins involved in muscle contraction and cellular motility. Her research aims to develop therapeutic strategies against cancer by inhibiting specific motors responsible for metastasis.
The EMBO Installation Grants provide three years of funding and support to seven talented researchers from Croatia, Czech Republic, Estonia, Hungary, Poland, Portugal, and Turkey. The grants aim to strengthen science in selected member states and foster their scientific and professional development.
The EMBO Young Investigator Programme selects Europe's most talented young researchers. Over three years, they receive financial and academic support to advance their careers through networking events, lab management training, and PhD courses.
EMBO has honored 59 leading life scientists from Europe and around the world with membership, including eight Associate Members. This recognition highlights the significant contributions of these researchers to the field of molecular life sciences.
A study analyzing 300 newspaper articles reveals five main 'gene frames' used by media, from deterministic to evolutionary and playful metaphors. The findings aim to provide a tool for scientists and journalists to better communicate genetics to the public.
EMBO recognizes Juergen Tautz for his outstanding public communication activity on honeybees, exploring their life and evolution, and promoting research through various media and educational initiatives.
Axel Meyer, a prominent German evolutionary biologist, has won the 2008 EMBO Award for his efforts to communicate complex scientific topics to the general public. He is recognized for his concise and opinion-strong articles on current issues like brain drain and science funding.
Two scientists, Gergely Szakács from Hungary and Monica Bettencourt-Dias from Portugal, will receive annual funding of €50,000 for three to five years. This grant supports their establishment of research groups in Hungary and Portugal.
Briscoe's work revealed a novel mechanism that allows cells to integrate time of exposure and concentration of Shh to mount a graded response, leading to a paradigm shift in understanding cell identity specification. His research has far-reaching implications for the control of cell identity in various contexts.
Researchers have solved the structure of two proteins that enable bacteria to develop resistance to various types of antibiotics, providing insights into their evolution and design strategies for new drugs. This discovery could aid in developing effective treatments against antibiotic-resistant infections.
Naama Barkai receives the award for her work on chemotaxis, embryonic development, and cellular transcription programmes. Her research has revolutionised the field of systems biology and significantly changed how scientists think about complex biological processes.
A European Molecular Biology Organization study reveals that traditional gender roles and negative workplace cultures limit women's career advancement. Women publish less, have fewer mentoring opportunities, and are slower to advance due to family responsibilities.
Low-density lipoprotein (LDL) contributes to vascular diseases by activating VEGFR1, accelerating macrophage migration and plaque progression. The discovery could lead to a potential therapeutic target for medical applications.
The European Molecular Biology Organization (EMBO) has selected 18 young scientists from Europe to receive the prestigious Young Investigator Programme. The three-year programme aims to support outstanding young researchers in developing their professional skills and reputation in the scientific community.
A recent study found that TPPII stimulates the formation of fat cells in worms and mammalian cells, leading to decreased fat stores. Mice with lower levels of TPPII were thinner than their wild-type littermates despite comparable food intake.
A study published in EMBO reports reveals that AKAP18, a crucial regulator of protein kinase A, may help the heart beat faster in response to adrenaline or noradrenaline. This could lead to improved survival rates for patients with heart failure and heritable heart disease.
French scientists Christian Sardet and Ali Saib have won the EMBO Award for Communication in the Life Sciences. They use innovative media to educate researchers, students, and the broader public about science.
Jan Löwe's groundbreaking research elucidated the structure and function of proteins involved in bacterial cell division, showcasing the complexity and sophistication of bacterial cells. His work highlights the importance of structural biology in understanding fundamental biological mechanisms.
Researchers suggest targeting beta1-integrin to treat cancer by reducing tumour cell proliferation and inducing cellular senescence, potentially preventing metastases. Blocking this protein function in transgenic mice with pancreatic insulinomas resulted in tumour cells becoming senescent and unable to form new tumours.
Researchers identified a sodium transporter gene that helps plants grow better in low-nutrient conditions. The OsHKT2;1 transporter allows plants to take up sodium, reducing the toxic effects of salt stress and even enhancing growth under nutrient-poor soils.
Aging cells with dysfunctional telomeres can promote tumorigenesis, but p53-mediated senescence may suppress spontaneous cancer development. Activating the senescence pathway is sufficient to prevent tumorigenesis in mutant mice with dysfunctional telomeres.
Researchers have identified a novel pathway in Trypanosoma brucei parasites that can be triggered to shut down the synthesis of a crucial RNA molecule, leading to parasite death. This discovery has implications for eradicating other parasitic diseases such as Leishmania and Chagas disease.