A recent study by Emory University and CDC found a significant increase in sepsis cases and deaths in the US over a 22-year period. The study suggests that factors such as antibiotic resistance, invasive procedures, and improvements in care among immunocompromised individuals are contributing to this trend.
A study of 1,383 cancer patients found that uninsured patients paid more for healthcare services but received significantly fewer treatments and services compared to insured patients. The disparity was attributed to various factors, including age at diagnosis and insurance coverage by race and ethnicity.
Emory researchers found that neurointensive care specialists can reduce mean length of stay by 34% for subarachnoid hemorrhage patients and 30% for ischemic stroke patients. Ventilator use also decreased by 76%, with a significant increase in opportunity days, indicating improved quality of care.
A study by Emory researchers found that controlling blood glucose levels through aggressive insulin therapy can significantly reduce mortality in critically-ill neurological patients. The research, conducted in a neurointensive care unit, used continuous intravenous insulin drip to achieve tighter control of glucose levels.
A two-year follow-up study shows participants with advanced PD experienced improvements in tremor, stiffness, slow movement, and balance. The new cell therapy, Spheramine, provided a source of increased dopamine production, maintaining initial gains up to 24 months post-treatment.
A new Emory University study reveals that depression has a negative impact on CABG outcomes, with depressed patients experiencing less improvement in physical function. The research emphasizes the importance of treating symptoms of clinical depression aggressively in cardiovascular disease patients.
A study of 1,045 patients found that depression significantly impaired physical function after CABG surgery. Patients with depression showed less improvement in physical function compared to non-depressed counterparts.
Researchers at Emory University have developed an innovative technique for biventricular resynchronization that minimizes risks and eliminates ionizing radiation. The new approach uses tiny incisions and specialized tools to connect leads to the heart, offering a safer and more efficient alternative to traditional methods.
Researchers examined 945 patients after coronary artery bypass grafting (CABG) and found that social support levels had little impact on rehab participation. Patients who participated in rehab were younger, better educated, more often worked, and less financially strained, but these factors alone could explain the difference.
At the ACC's 52nd Annual Scientific Session, Emory Heart Center physicians will share information on the latest advances in cardiovascular medicine. Dr. Douglas Morris will present on new biological insights and approach to post-bypass patients, highlighting recent achievements in cardiac rehabilitation.
Functional nanoparticles are being developed for molecular imaging, cancer treatment, and tissue engineering. Scientists can engineer nanoparticles to have multiple functions, including tagging proteins or genetic sequences in a process called multiplexing.
Dr. Nie constructs smart nanoparticle probes to recognize DNA sequences and genetic mutations, enabling early cancer diagnosis and personalized medicine. The nanobeacons can profile multiple genes and proteins simultaneously, allowing for individualized cancer treatments based on molecular differences.
A $10 million grant will fund a new prostate cancer research consortium led by Emory University, comprising 13 universities from eight states. The consortium aims to identify new therapeutic targets for advanced prostate cancer treatment.
A recent study found that adolescents with high exposure to rap music videos were 3 times more likely to hit a teacher and twice as likely to have multiple sex partners. The researchers also discovered that frequent viewers of rap videos were more likely to acquire an STD, use drugs, and engage in other risky behaviors.
Adverse experiences in early childhood can lead to changes in brain structure, gene expression, and neurotransmitter function, increasing sensitivity to stress. This increased stress sensitivity is a significant risk factor for mood disorders and medical diseases.
Researchers found a connection between HIV antiretroviral therapy and impaired triglyceride metabolism, increasing risk of atherosclerosis. Elevated ApoC-III levels were associated with higher triglycerides in both treatment groups.
Researchers found a significant inverse correlation between circulating endothelial progenitor cells and cardiovascular risk factors. They also discovered that individuals with higher cardiovascular risk factors experience premature aging of these cells.
A new AIDS vaccine strategy has been developed by Emory University researchers and is now moving to human clinical trials. The vaccine, which employs two different components, aims to induce the immune system to recognize HIV's distinguishing features, providing a safer alternative for HIV prevention.
Researchers found that the absence of the SAP gene impairs the immune system's ability to recognize and react to infection, leading to impaired long-term antibody responses. The study has implications for vaccine development and may offer therapeutic benefits in treating X-linked lymphoproliferative disease.
A study of over 40,000 individuals reveals that non-physician clinicians are increasingly providing preventive services and working with physicians to care for patients. The findings highlight the importance of effective communication and coordination between physician and non-physician clinicians to improve care quality.
A study by Emory University scientists identified the MAP kinase signaling pathway as a key player in early melanoma development. The researchers found that this pathway is abnormally activated in early melanomas, but not in precancerous moles. This finding has implications for diagnosis and treatment of melanoma.
A recent Emory University study reveals that the majority of baby-boomers fall short of good health, with 62.2% categorized as 'incompletely healthy'. The research emphasizes the need for healthcare providers to adopt a more holistic approach, focusing on disease prevention and health promotion rather than just treating illness.
Lymphatic filariasis is a leading cause of permanent and long-term disability, resulting in physical suffering and psychosocial problems. Continued research is essential to measuring LF elimination efforts and making adjustments as the program moves into new challenges.
The Emory Center for AIDS Research (CFAR) has received a five-year grant from the National Institutes of Health to further HIV/AIDS research and prevention efforts. With $33.5 million in NIH funding, the CFAR will build on recent advances in immunology, vaccines, and drug development.
A study estimates that US HIV prevention efforts saved between 204,000 to 1.585 million lives and resulted in cost savings of at least $11 billion since the onset of the epidemic, with a cost per infection prevented ranging from under $50,000 to $6,400.
A new model developed by Emory University researchers suggests that targeted smallpox vaccinations could be an effective intervention against deliberate attacks. The study found that rapid response and targeted vaccination strategies can significantly reduce the spread of smallpox, particularly when pre-existing immunity is considered.
Researchers at Emory University Health Sciences Center found that early, aggressive treatment for acute coronary syndromes is more cost-effective over time due to decreased medical and other expenses. This approach offers the best prognosis for patients and reduces major cardiac events.
Researchers have developed a new surgical procedure for Parkinson's disease, bilateral subthalamotomy, which has shown promising results in improving motor symptoms and activities of daily living. After two years of follow-up, patients exhibited approximately 50% improvement in motor symptoms and significant reduction in medication doses.
A landmark study shows that high doses of coenzyme Q10 can slow the progression of Parkinson's disease, measured by movement difficulty or disability. The study found significant reductions in motor disabilities, mental function, and mood among participants taking the nutrient.
The National Lung Screening Trial will enroll 50,000 current or former smokers in the US to compare the effectiveness of CT scans and chest X-rays in detecting lung cancer. The trial aims to determine if early detection can lead to a reduction in lung cancer deaths.
A study by Emory University Health Sciences Center found that many young men have trouble using condoms correctly, with errors including not checking expiration dates and putting on condoms during sex. The research emphasizes the importance of providing adequate condom use education to prevent HIV and other STDs.
Emory University will lead a new center studying the relationship between environmental agents and Parkinson's disease, with research focusing on pesticides, organochlorine insecticides, and genetic causes of PD. The center aims to develop strategies for prevention and treatment.
Researchers at Emory University's Winship Cancer Institute are studying cellular responses to environmental stress to better understand how it contributes to cancer development. The team aims to characterize networks of systems that operate during exposure to DNA-damaging events, with a focus on DNA repair and damage tolerance pathways.
A recent study found a significant change in the types of bacteria involved in early-onset sepsis in low-birth-weight infants, with an increase in E. coli cases and antibiotic-resistant strains. The shift raises concerns about the impact of increasing antibiotic use during labor on these vulnerable infants.
The study found that cooperative behavior is intrinsically rewarding to the human brain, activating areas linked to reward processing. Mutual cooperation was common in games played with presumed human partners, even when a player was maximally rewarded for defecting.
A recent study by Emory University Health Sciences Center found that lower levels of social capital are associated with higher rates of sexually transmitted diseases. The research, which analyzed data from 48 US states, discovered that social capital is a significant predictor of infectious diseases including AIDS and STDs.
A retrospective study of 222 patients with HIV found that women experienced higher rates of neurologic complications and lipodystrophy after two years of HAART therapy. The study's findings suggest that while women may respond similarly to treatment as men, they experience more side effects.
A new study by Emory University and CDC reveals a surge in sepsis cases across the US, with significant increases in hospitalizations among specific demographics. The incidence of sepsis rose in both children and adults over a 20-year period, with gram-positive infections becoming more prevalent.
Researchers at Emory University Health Sciences Center are launching a three-year pilot study to evaluate the effectiveness of progesterone in treating traumatic brain injury. The study aims to determine whether giving progesterone to victims of moderate to severe traumatic brain injury can save lives and preserve mental function.
Emory University is conducting a clinical trial to evaluate an improved anthrax vaccine regimen with reduced injections and muscle administration. The study will enroll 1,560 volunteers across six sites and aim to simplify the existing dosing schedule while providing more data on safety.
A new pneumococcal vaccine has been shown to significantly reduce the incidence of pneumonia and invasive disease in children in Soweto, South Africa. The vaccine, which includes two additional strains of pneumococcus prevalent in developing countries, reduced pneumonia by over 20% and invasive disease by 50-80%.
Chronic alcohol abuse can lead to life-threatening lung disease due to glutathione depletion. Glutathione depletion leaves the lungs vulnerable to injury when a serious illness such as sepsis or pneumonia occurs. Effective therapies for preventing and treating chronic alcohol abuse-related lung damage are still being designed.
Researchers have found that MMP enzymes recruit circulating inflammatory cells to form atherosclerotic plaques, which can lead to acute cardiovascular events. The study also reveals the complex roles of MMP enzymes in remodeling the extracellular matrix, suggesting new therapeutic strategies to limit plaque growth.
Researchers discovered two mechanisms by which adenoviruses establish persistent infections: interfering with apoptosis signaling and preventing apoptosis through the Receptor Internalization and Degradation complex. This knowledge could improve the usefulness of adenovirus vectors in gene therapy.
A study by Emory University researchers found that the atypical antipsychotics quetiapine and clozapine reduced hallucinations in patients with advanced Parkinson's disease. The medication group also showed a lower risk of nursing home placement, suggesting long-term benefits.
A Phase I trial has shown that retinal cell implantation can improve motor function in advanced Parkinson's disease patients by nearly 50 percent, according to researchers at Emory University. The implanted cells provide a source of increased dopamine production, helping to alleviate symptoms such as tremors and stiffness.
Researchers at Emory University Health Sciences Center have found a potential link between low testosterone levels and non-motor symptoms of Parkinson's disease in men. Testosterone replacement therapy showed significant improvement in patients with refractory symptoms, including fatigue, depression, anxiety, and decreased libido.
Researchers found that ropinirole slowed the loss of dopamine function in early stages of Parkinson's disease by over 30 percent compared to levodopa. The REAL-PET study used positron emission tomography (PET) brain imaging and showed significant slowing of dopamine loss, which could lead to a better quality of life for patients.
The new center will explore various initiatives toward insulin independence without long-term immunosuppression. Researchers will investigate less toxic drugs and test donor islets protected by a sheath-like membrane to reduce immune response.
The Emory study uses the COGNIShunt device to drain off toxins from the cerebrospinal fluid, a potential breakthrough in treating Alzheimer's disease. The 18-month trial aims to assess the effectiveness of the treatment and its impact on patients' symptoms.