A new clinical trial is investigating the combination of high-dose calcitriol and docetaxel in treating advanced prostate cancer, with the goal of reducing PSA levels by 50% or more. The study builds on promising preliminary results from a previous Oregon Health & Science University trial.
Scientists are developing a new space weather model that can mimic solar explosions, auroras, and geomagnetic storms. The National Center for Atmospheric Research (NCAR) will provide a computer model of Earth's upper atmosphere to aid the effort.
Researchers found diatoms use glass to facilitate photosynthesis, which benefits the planet by reducing carbon dioxide levels. This discovery links carbon cycles and silicon chemistry, providing insights into historical climate variations and greenhouse gas emissions.
The NIH Autism Coordinating Committee has selected two new centers to conduct autism research, expanding the agency's commitment to the field. The centers will focus on understanding the causes, diagnosis, and treatment of autism, with a goal of advancing knowledge about this devastating condition.
Climate change is expected to increase winter temperatures, leading to greater risks for perennial forage crops in Eastern Canada. The study used agro-climatic indices to analyze the effect of climate conditions on winter survival, finding increased risks due to warmer winters and reduced cold hardiness.
Researchers have found an enzyme that activates specific RNAs outside the nucleus, enabling them to carry out important steps of germ line development. The discovery provides an important piece of the puzzle in understanding how genes are controlled and may lead to new ways of regulating genetic information.
The National Lung Screening Trial will enroll 50,000 current or former smokers in the US to compare the effectiveness of CT scans and chest X-rays in detecting lung cancer. The trial aims to determine if early detection can lead to a reduction in lung cancer deaths.
Duke University psychologists found that infants who used 'sticky mittens' had more sophisticated abilities to explore objects and showed increased cross-sensory exploration. The study suggests that providing rich opportunities for infant learning is crucial for development.
A study published in Biochemistry found significant alterations in white matter tissue of Alzheimer's patients, suggesting a potential initiating step for the disease. White matter degeneration may be caused by a disease of oligodendrocytes, leading to axon damage and cognitive impairments.
A study by Georgia Tech reveals that individuals with optimistic outlooks, high self-esteem, and conscientious personalities tend to have more success in their job searches. Additionally, a change in daily routine can positively affect re-employment prospects, particularly for older workers.
Drs. Gerald DiBona and John Hall have overturned the medical community's long-held understanding of kidney function, revealing that increased nerve activity leads to high blood pressure. Their research shows that abnormal kidney function causes salt and water excretion to decrease, resulting in hypertension.
A new study by Stanford University geophysicists challenges the widely used time-predictable recurrence model, which estimates the time when an earthquake will occur. The researchers found that the model failed to predict a magnitude 6 quake on the San Andreas Fault in Central California.
Researchers at the University of Florida have demonstrated a novel approach to overcoming gene therapy hurdles by attaching viruses to tiny manufactured balls coated with iron oxide. The microspheres can be targeted using magnets, allowing for more efficient delivery of corrective genes to specific organs or tissues.
Research by Dr Michal Lyons examines the experiences of would-be home-owners in seven cities, revealing that delays in getting a foothold are worst in London and major metropolitan areas. Parental home ownership is crucial for young people's chances of becoming homeowners.
Researchers identified a green tea compound that may block a key cell receptor involved in allergic responses, potentially providing an anti-allergenic effect. The study found that the compound, methylated EGCG, is more potent than previously discovered compounds and may work against various allergens.
Researchers at TSRI have uncovered a mechanism by which plants adjust their flowering cycles to optimize productivity. By manipulating the timing of plant development, crops may be able to produce faster and more nutritious yields.
HHMI has selected 20 'million dollar professors' to promote groundbreaking research in STEM fields and enhance undergraduate education. These experts, including Sarah Elgin, will develop innovative teaching tools and curricula to address the growing demand for interdisciplinary knowledge.
A study found that mentally ill individuals are vulnerable to victimization in conflict situations, particularly those with substance abuse disorders or delusional beliefs. Counseling services can help family members and professionals cope with these individuals while avoiding conflicts.
Researchers have identified two compounds, NAP and SAL, that can prevent ethanol's disruption of L1-mediated cell adhesion, a critical process for brain development. These findings bring the study of fetal alcohol syndrome closer to effective interventions.
A new class of composites has been developed that can store electric charge more efficiently, enabling the creation of artificial muscles and tendons with improved motion. The material also has potential applications in microfluidic systems for drug delivery and smart skins for drag reduction.
The National Lung Cancer Screening Trial (NLST) is a randomized, controlled study aiming to determine the effectiveness of spiral CT scans versus chest X-rays in reducing deaths from lung cancer. Participants will receive annual screenings for three years and their health will be monitored until 2009.
The Robert Wood Johnson Foundation has awarded grants to ten dental schools to expand community-based education programs and increase enrollment of underrepresented minority students. The goal is to reduce gaps in dental care for underserved populations and create a more diverse dental workforce.
Researchers at Stanford University broke the learning process down into smaller steps for adult owls, allowing them to adjust their mental maps more accurately. This method showed promise in overcoming the age-related decline in learning abilities, with implications for treating brain injuries and improving physical therapy outcomes.
The HHMI Professors, 20 research scientists at 19 universities, will focus on engaging and effective approaches to undergraduate science education. They will develop new high-tech teaching tools, provide early research experiences, and mentor minorities to promote diversity in STEM fields.
Researchers have solved the structure of the pre-budding complex, a set of proteins that plays a key role in forming vesicles on the cell's endoplasmic reticulum. The study reveals how the complex assembles on the ER membrane and initiates the process of membrane cargo capture and vesicle budding.
A study by Texas A&M University found that even small amounts of alcohol can impair driving skills and increase the risk of accidents. Drivers with a blood alcohol concentration as low as .04 (half the legal limit) showed significant impairment in their abilities, highlighting the dangers of drinking and driving.
Research by Dugatkin and colleagues shows that observing fights in swordtail fish affects their likelihood of winning. Psychological factors play a significant role in animal societies, predicting the outcome of interactions between group members. These findings have implications for understanding human social dynamics.