A study of 34,708 postmenopausal women found that compliance with the Dietary Guidelines reduced overall cancer incidence by 5-15% across quintiles. Regular exercise and weight management also played a significant role in reducing breast, colon, and uterine cancer risk.
A study published in Science reveals a new risk factor for colon cancer, associated with the Bloom syndrome gene mutation. Researchers found that individuals carrying the mutated gene had nearly three times the risk of developing colon cancer compared to those without the mutation.
A 10-week study found that participants consuming artificial sweeteners lost an average of 1 kg, while those consuming sucrose gained 1.3 kg of fat mass and rose in blood pressure. The authors suggest overweight individuals consume beverages with artificial sweeteners to prevent weight gain.
The study found that hormone replacement therapy (HRT) increases the risk of breast cancer, pulmonary embolism, and stroke in women, while reducing the risk of colorectal cancer and hip fractures. HRT may also increase the risk of cardiovascular disease among older women.
A randomized controlled trial found that sildenafil reduced pulmonary blood resistance, a key indicator of pulmonary hypertension. The study suggests sildenafil could be a promising candidate for long-term treatment of secondary pulmonary hypertension in lung fibrosis. Controlled trials are needed to confirm the findings.
African-American patients are 71% as likely as white patients to receive a referral for coronary angiography, but only 63% actually undergo the procedure. Private insurance and patient preference may play roles in the disparity.
The UCI-based center will utilize mass spectrometry to measure radiocarbon in plants, soils and ocean coral, providing insights into the global carbon cycle. This technology enhances Earth system science research and strengthens UCI's interdisciplinary scientific study capabilities.
Researchers discovered a possible novel pathway for colon cancer in humans, associated with a single BLM mutation. The study found that almost two percent of patients with colon cancer carried the BLMAsh mutation, compared to less than one percent of healthy individuals.
Scientists at Oregon State University have made a groundbreaking discovery about the role of micro-RNA in regulating gene expression. Micro-RNAs are found to cut messenger-RNAs in half, interfering with their function and controlling the process of cell differentiation.
The award recognizes Laing's successful implementation of diversity strategies, including promoting women to management roles and supporting part-time employees. With nearly 25% of unit managers being women, his work has significantly altered the demographic makeup of Xerox's supplies delivery unit.
Researchers found thicker, denser storm clouds over warmer waters, covering wider areas of the tropics and releasing more moisture as rain. This contradicts the 'Adaptive Iris' theory, which suggests cloud cover decreases with rising ocean temperatures.
The newly revealed hieroglyphs at Dos Pilas shed new light on a critical period of Maya history, revealing a complex web of alliances and conflicts between Tikal and Calakmul. The inscriptions clarify the political and military relationships between these two superpower blocs, which dominated the region in the seventh century.
A new experimental technique called adoptive transfer has shown significant promise in treating metastatic melanoma by replacing immune cells with those specifically designed to destroy tumors. The treatment resulted in at least 50% tumor shrinkage in six patients, with no growth or appearance of new tumors.
The Sister Study aims to investigate the causes of breast cancer by recruiting 50,000 sisters of women with breast cancer. The researchers will collect biological and environmental samples, as well as questionnaires about health histories, environmental exposures, and lifestyles.
A Cincinnati ossuary has been discovered to feature a unique image of a massive Jerusalem tomb from the first century, associated with early Rabbi Hillel and Jesus of Nazareth. The ossuary's distinctive three pyramids have garnered attention from scholars, providing new insights into ancient Jerusalem's architecture.
Penn researchers have identified a key gene, Hop, that plays a vital role in regulating the development of heart cells. By inhibiting the expression of another important regulator, serum response factor (SRF), Hop protects cardiac muscle cells from over-development and fatal abnormalities.
A new therapy boosts the immune system's targeted assault on tumors, shrinking melanoma in human patients. The approach involved suppressing the patients' immune systems to make room for new cells that attacked and killed tumor cells.
Researchers at UT Southwestern Medical Center have discovered a protein called Homeodomain-Only Protein (HOP) that regulates heart growth from fetal stage to adulthood. HOP helps control the balance of cardiac cell proliferation and differentiation, with disrupted levels leading to abnormal heart development.
Active mountains, despite constant uplift, do not get taller because of erosion forces balancing uplift and sediment transport. Researchers found that river erosion rates closely match the rate at which rocks move up, with abrasion by suspended particles doing most of the down cutting.
A team of researchers, led by Josef Penninger, found that the PTEN and PI3K alpha and gamma proteins work together to regulate heart size. They also discovered that when these proteins are shut down, large hearts can pump more efficiently than normal-sized hearts.
Researchers used the GISS SI2000 climate model to simulate past and future global temperature changes, finding that human-made forcings are mainly responsible for recent warming. The study suggests that reducing air pollution and stabilizing carbon dioxide emissions could limit warming to 0.75°C over the next 50 years.
The new 800 MHz magnet will enable researchers to study larger and more complex biological systems, including protein folding and complex formation. This advancement is expected to significantly improve understanding of normal biological function and regulation, as well as the development of diseases and drug response.
In a 6-month study, black women experienced a 26% decrease in daily energy expenditure after weight loss, while white women saw a 16% increase. The authors conclude that black women's decline in physical activity increases their risk of weight relapse.
A study of 58 children with high cholesterol found that girls with hypercholesterolemia were more likely to become overweight or obese by age 11-12 compared to their peers. The researchers propose that abnormally high cholesterol may be a marker of an altered metabolism leading to excess adiposity.
A genetic mutation common among Ashkenazi Jews can double the risk of colorectal cancer. Researchers discovered this relationship through an international study analyzing DNA from nearly 3,100 individuals.
The laser technique, called LIBS, can detect various explosives and identify close relatives of anthrax in instant detection. A portable LIBS system could continuously monitor air for signs of chemical or biological agents, alerting officials to potentially hazardous substances.
A recent study published in New England Journal of Medicine found that genetically identical twin pairs had similar breast densities, while non-identical pairs had breast densities about half as similar. This suggests that genetic factors play a major role in explaining why women of the same age have different breast density.
A study of 9019 participants found that waist circumference correlates better than BMI with most CVD risk factors. The authors propose WC
The top-ranked company, Genentech, is praised for its alignment of work culture and personal values, as well as its commitment to translating scientific discoveries into medicine. Millennium Pharmaceuticals ranks second, with a strong focus on attracting leading scientists and providing them with the tools to practice their science.
A recent study found that breastfeeding had no significant effect on the risk of developing asthma or allergies in childhood. In fact, children who were breastfed for more than four weeks were twice as likely to develop allergic disease or asthma compared to those who were not breastfed.
Researchers found that Nocaine is a weak reinforcer, providing some of cocaine's effects but at a lower level. This makes it less likely to be abused and have abuse-related toxicity.