A recent study found that women undergoing bypass surgery experience less improvement in depression, shortness of breath, and health-related physical limitations compared to men. Women also reported a more negative evaluation of their surgery and recovery process.
Researchers found that atropine drops can work just as effectively as patching in treating amblyopia, a condition of poor vision in one eye. Compliance is key, and the drops offer a convenient and stigma-free option for children and older patients.
A new office at Emory University aims to strengthen public health infrastructure and capacity to address emerging infectious diseases and those caused by terrorism. The office, led by Dr. Ruth Berkelman, will coordinate with public health officers on a county and statewide level.
Researchers discovered that Nox1 enzyme generates reactive oxygen molecules that trigger angiogenesis and tumor growth. Inhibiting Nox1 activity or reducing hydrogen peroxide levels may decrease cancer cell growth and increase sensitivity to chemotherapy.
Researchers at Emory University Health Sciences Center revealed the architecture of MAO B's active site and membrane binding sites, enabling improved drug design with increased specificity and fewer side effects. The study also highlights potential applications in treating depression and neurodegenerative diseases.
Researchers at Emory University Health Sciences Center have identified specific genes in the brain associated with Fragile X Syndrome, a genetic disorder causing mental retardation and related problems. The study used DNA microarray technology to discover 251 dysregulated mRNAs in cells from patients with fragile X syndrome.
Researchers used gene transfer to increase vasopressin receptor density in the ventral pallidum of prairie voles, leading to increased pair bonding. The study shows that higher levels of vasopressin receptor expression are associated with more affiliative behavior and stronger pair bonds.
The study found that traditional medical school curricula have failed to promote humanism in physicians-in-training. In contrast, bedside interactions and hands-on experience are seen as key to fostering positive attitudes and skills.
Researchers at Emory University found that growth factor BDNF stimulates the production of new neurons in several areas of the adult brain, including the striatum and hypothalamus. This discovery suggests a more profound capacity for neurogenesis in the adult forebrain than previously thought.
Researchers at Emory University found that temporal lobectomy significantly reduces complex partial seizures in patients with temporal lobe epilepsy (TLE) who cannot be controlled by medication. However, the procedure is less effective in reducing generalized tonic-clonic seizures, also known as grand mal seizures.
Despite an increasingly difficult patient population, Emory's success rate in angioplasty has progressively increased, while complications have decreased. The institution's 20-year experience shows reduced hospital stay lengths and lower costs.
Emory researchers discovered that abnormal gene silencing, caused by overexpression of methyltransferase enzymes, can lead to breast cancer progression. The silencing of the TMS-1 gene, responsible for programmed cell death, may contribute to tumor growth and resistance to conventional therapies.
The Emory-led research group aims to use naturally occurring sphingolipids to develop more effective compounds for cancer prevention and treatment. Sphingolipids have shown promise in controlling certain types of cancer, and the grant will focus on developing these compounds into new anti-cancer treatments.
Researchers from Emory University Health Sciences Center have identified three HIV-positive chimpanzees that are progressing to AIDS, offering insights into how the disease develops and may be resisted. The chimps' unique genetic profile could hold key to developing an HIV vaccine and new treatments for AIDS.
A DNA-based flu vaccine has shown promising results in a mouse study, generating high levels of neutralizing antibodies and providing protection at a lower dose. The vaccine combines C3d with HA glycoprotein, priming the immune system against influenza.
Researchers have discovered that synthetic superoxide dismutase and catalase can extend the lifespan of C. elegans nematode worms by approximately 50%. These catalytic drugs convert oxygen radicals into water, reducing oxidative stress and protecting mitochondrial function.
Researchers at Emory University Health Sciences Center discovered that non-pathogenic bacteria in the GI tract can block an immune system pathway called NF-KB, preventing cells from responding to potential threats. This mechanism may play a crucial role in the pathogenesis of inflammatory bowel disease and other intestinal diseases.
Scientists have discovered that mutant protein fragments selectively accumulate in the nuclei and axon terminals of neurons in the brain affected by Huntington's disease. This accumulation is thought to inhibit neurotransmitter release, causing the death of specific neurons.
A study by Emory University researchers found that women who experienced childhood abuse have elevated hormonal responses to stress, which may contribute to greater vulnerability to depression and anxiety disorders in adulthood. The study suggests that early-life trauma plays a major role in the development of mood and anxiety disorders.
A study published by Emory University researchers found that a naturally occurring neurotransmitter called CART peptide produces behaviors associated with cocaine and methamphetamine. The finding suggests a role for the brain chemical in modulating or mediating the actions of drugs and potentially treating addiction.
Scientists at Emory University Health Sciences Center have discovered that the oxytocin gene is necessary for forming social memories, allowing individuals to recognize familiar faces. The study found that mice lacking this gene exhibited social memory deficits, which were restored with oxytocin treatment.
A study by Emory University neurologists found that pallidotomy surgery significantly improves motor function in patients with Parkinson's disease, with persistent benefits extending to both sides of the body. The long-term effectiveness of this treatment has been confirmed through a 36-month follow-up.
A study of 50 patients at the Veterans Affairs Medical Center in Atlanta found that rectally administered lidocaine gel significantly reduced pain during transrectal prostate biopsy. Patients who received lidocaine rated their pain as moderate to severe, while those without anesthetic experienced more discomfort.
A new software program developed by Emory researchers uses data from 840 previous patients to predict outcomes in new patients. The genetic adaptive model has an accuracy rate of 76 percent and can help determine a patient's chances of cancer recurrence after treatment, guiding doctors towards the best treatment option.
Emory University researchers suggest that glutathione could be used as a flu preventive by exposing it directly to the tissues lining the mouth and upper airway. Studies have shown that glutathione reduces cellular damage caused by reactive oxygen, but its effectiveness in preventing disease has been unclear.
Capuchin monkeys have been found to cooperate in obtaining food by working together and sharing the rewards. This study by Frans de Waal and Michelle Berger suggests that reciprocity is a fundamental feature of human society and has implications for understanding evolutionary cooperation.
Researchers at Emory University have uncovered a significant connection between mast cells and the development of multiple sclerosis. Mast cells, previously only studied in respiratory tract diseases like hay fever and asthma, are now linked to nerve damage in MS.
A study by Emory University researchers found that Wernicke's area, a region of the brain known for language processing, also monitors nonverbal predictability. This suggests that our ability to acquire language may stem from our subconscious recognition of predictable events.
Researchers successfully demonstrated the effectiveness of a new oral form of ganciclovir to treat CMV retinitis, a blinding disorder that affects AIDS patients. The experimental valganciclovir offers a simpler treatment option with fewer pills needed per day.
Emory researchers verify the role of visual cortex in processing sensory information, including touch. The study reveals that visual imagery facilitates tactile discrimination tasks, such as distinguishing orientation via touch.
Scientists at Emory University discovered a new family of enzymes linked to abnormal cell growth in cancer and cardiovascular disease. The Mox1 enzyme converts oxygen into reactive oxygen molecules that instruct cells to divide more rapidly.
Scientists at Emory University create transgenic mice with a prairie vole vasopressin receptor gene, showing increased social behavior and adopting gregarious behaviors. The study provides an explanation for the species difference in receptor distribution and its impact on social behavior.
The NSF award establishes a Center for Behavioral Neuroscience, focusing on complex social behaviors and emotions. The center will study brain mechanisms and develop powerful new technologies.
The study found that aggressively lowering 'bad' cholesterol with atorvastatin reduced ischemic events by 36% compared to balloon angioplasty, delaying cardiac events in patients with stable coronary artery disease. Researchers concluded that this therapy is a safe and effective initial strategy for reducing ischemic events.
Chimpanzees demonstrate ability to visually recognize and match portraits of female relatives, potentially aiding kinship decisions and alliances. This skill may have played a role in the evolution of complex societies among primates.
Scientists have developed a new marking system that allows them to visualize and track immune memory cells for the first time. This breakthrough has significant implications for vaccine development, organ transplantation, and the treatment of autoimmune diseases.
A new study found that early t-PA treatment can have a long-lasting benefit for patients who experienced a stroke. Within three hours of symptoms onset, patients treated with tissue plasminogen activator (t-PA) were at least 30% more likely to have minimal or no disability at 12 months compared to placebo-treated patients.
Researchers found that low doses of Tacrine hydrochloride reduced motor and vocal tics in adults with Tourette syndrome. The study also showed dose-related improvement in comorbid symptoms such as attentional difficulties, hyperactivity, and obsessive thinking.
The American Psychiatric Association is establishing the first comprehensive guidelines for treating persons with HIV infection and AIDS. The new guidelines will focus on access to care, treatment adherence, education, prevention, and direct mental health services.
Researchers at Emory University found that 25 patients with depression failed to respond to conventional treatment showed significant improvement after receiving electromagnetic stimulation. The study suggests that rTMS may be a viable option for patients with treatment-resistant depression.
A DNA vaccine developed by Emory University researchers protects monkeys against HIV challenge infections, demonstrating a promising step towards an effective AIDS vaccine. The vaccine uses a two-step approach, priming the immune system with a DNA vaccine and followed by booster immunizations with a pox virus.
Researchers identified a mechanism by which cytosine substitution can occur in non-dividing cells, leading to the production of mutant proteins. This process has significant implications for understanding age-related cell death, neurodegenerative diseases, and malignant transformation.
The Emory-led WASID study aims to compare the effectiveness of warfarin and aspirin in preventing stroke and vascular death in patients with intracranial stenosis. The five-year trial will evaluate 806 high-risk patients at 50 sites across North America.
A study by Emory University infectious disease specialists found that most inner-city HIV patients hospitalized for HIV or AIDS had not received outpatient care or HAART therapy in six months prior. Despite the effectiveness of combination drug therapy, patients often fail to take advantage of available resources.
Research by Frans de Waal suggests that chimpanzees resolve conflicts through cooperative behaviors, such as food sharing, which can inform our understanding of human aggression. By studying chimp societies, de Waal's research provides insights into the complex social system and reconciliation mechanisms that repair relationships.
Researchers at Emory University Health Sciences Center discovered that the visual experience of one eye influences the growth and quality of vision in the fellow eye. The study found that environmental factors play a significant role in eye development, suggesting a potential cure for myopia and related eye problems.
A new study by Emory researchers found that HIV patients treated with protease inhibitors are more likely to engage in risky sex, including inconsistent condom use. The study also reveals significant differences in condom use among men who had sex with men (MSM) and heterosexual men or women.
A recent study found that teenage girls who engaged in HIV-related sexual risk taking and were currently pregnant viewed more television programs depicting violence, women's abuse, or demeaning behavior. This suggests the need for TV networks to decrease violent content and promote healthy sexual behaviors.
Emory University researchers suggest that high estradiol levels increase MPO, which oxidizes LDL and clears it via the liver. This mechanism may explain estradiol's protective effects on cardiovascular disease.
Researchers at Emory University found that vitamin E supplementation decreased autoantibodies associated with oxidation of lipoproteins in healthy women. The study suggests that antioxidants like vitamin E may help attenuate oxidation and reduce the risk of atherosclerosis.