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Microbiology Society


Targeting hit-and-run cancer viruses

Scientists at the University of Cambridge have developed a vaccine to stop cancer-causing viruses that invade host cells, initiate cancer, and then disappear. The vaccine has been shown to protect against subsequent cancer development in mouse models, holding promise for preventing human cancers.

SourceMicrobiology Society·JournalJournal of General Virology·DateAug 18, 2010

New breakthrough in fight against lethal CCHF virus

Scientists have developed an immune-deficient mouse model to study CCHF virus behavior in humans, a significant step towards vaccine and antiviral development. The model can help evaluate the safety and effectiveness of potential treatments, addressing the lack of suitable animal models for testing.

SourceMicrobiology Society·JournalJournal of General Virology·DateMay 17, 2010

UTIs becoming harder to treat

Researchers discovered an identical gene for antibiotic resistance in human and animal samples, suggesting its transfer between bacteria species. This finding poses a risk to the treatment of common human infections like UTIs, which are increasingly difficult to treat due to rising antibiotic resistance.

SourceMicrobiology Society·JournalJournal of Medical Microbiology·DateMay 17, 2010

Rare toxic algae identified

Scientists have identified a rare species of pathogenic algae causing human skin infections and septicemia. The discovery may lead to better treatment protocols and economic benefits for the dairy industry.

SourceMicrobiology Society·JournalINTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY·DateMay 10, 2010

Fly gut bacteria could control sleeping sickness

A new bacterial species found in the fly that transmits African sleeping sickness has been identified as a potential tool for controlling the disease. The bacterium, named Serratia glossinae, has shown promise in killing the parasite that causes the disease and could lead to new treatment strategies.

SourceMicrobiology Society·JournalINTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY·DateMay 10, 2010

Fighting fungal infections with bacteria

Researchers found that Pseudomonas aeruginosa bacteria can inhibit Candida albicans biofilm formation on silicone surfaces. This discovery could lead to the development of new antimicrobial drugs and additives to prevent hospital-acquired fungal infections.

SourceMicrobiology Society·JournalMicrobiology·DateMay 1, 2010

Flu jab for bacteria

Bacteria have a CRISPR defence system that can be passed down to future generations, providing immunity against viral attacks. This system could be exploited to give bacteria 'flu jabs' to protect them against real-world threats, increasing industrial productivity and reducing costs.

Stem cell therapy to tackle HIV

A novel stem cell therapy has been developed to arm the immune system against HIV, potentially improving quality of life and life expectancy for those who have failed antiviral drugs. The therapy involves delivering antiviral DNA to patient immune cells, which can block viral gene production using RNA interference.

Bile sends mixed signals to E. coli

Bile helps E. coli O157:H7 bacteria survive by increasing iron uptake, while reducing attachment to host cells in the large intestine. This study could lead to better protection of food from contamination and a deeper understanding of bacterial disease mechanisms.

Essential oils to fight superbugs

Researchers found that thyme essential oil can almost completely eliminate bacteria within 60 minutes, with high efficacy against Staphylococcus species. The study suggests that essential oils could be a cheap and effective alternative to antibiotics, reducing the risk of new strains of antibiotic-resistant micro-organisms.

Fat clue to TB awakening

Researchers have discovered that Mycobacterium tuberculosis stimulates macrophages to accumulate fat droplets, turning them into 'foamy' cells that can reawaken the latent TB infection. This cellular transformation allows the bacteria to leak out into the airways and progressively destroy lung tissue.

Bacteria toxic to wound-treating maggots

Researchers found that maggot 'biosurgeons' used to treat chronic wounds are vulnerable to deadly bacteria Pseudomonas aeruginosa, which can kill the maggots within 20 hours. This discovery could lead to more effective treatment of wounds and development of novel antibiotics.

SourceMicrobiology Society·JournalMicrobiology·DateFeb 4, 2010

How clean is your knife?

Researchers developed a rapid-acting disinfectant that kills bacteria, viruses and fungi on surgical instruments, including those resistant to conventional disinfectants. The new formula is safer, cheaper and more effective than existing treatments against prions, which cause deadly illnesses.

SourceMicrobiology Society·JournalJournal of General Virology·DateJan 19, 2010

Taking the stress off yeast produces better wine

Researchers have identified genes in yeast that enable it to respond to stress and are investigating ways to improve its performance by modifying its stress response mechanism. By manipulating these genes, they found a family of enzymes called sirtuins plays an important role in controlling wine yeast lifespan.

Using insects to test for drug safety

Researchers use insects like fruit flies and moths to test new drugs, reducing animal testing by up to 90% and speeding up results. The study finds that insect immune cells are structurally and functionally similar to those in mammals, offering a promising alternative for drug development.

Designing probiotics that ambush gut pathogens

Researchers have designed probiotics that can bind toxins in the gut, preventing them from interacting with host intestinal cells. These receptor-mimic probiotics offer a promising treatment for diseases such as cholera and traveller's diarrhoea, and may also be used to prevent outbreaks following natural disasters.

Using waste to recover waste uranium

Scientists have recovered uranium from polluted waters using bacteria and inositol phosphate, a cheap waste material. The process is economically viable, especially as the world price of uranium is likely to increase, offering an environmental protection benefit.

Making more efficient fuel cells

Researchers have discovered a strain of bacteria with pilin proteins that can conduct electricity, leading to increased power output in microbial fuel cells. This breakthrough could enable the use of microbial fuel cells in remote environments and monitoring devices, such as ocean floor sensors, to convert waste into electricity.