Half of patients with advanced CKD delay AVF creation, often starting with temporary vascular access despite education. Researchers found that beliefs about the value of vascular access predict intentions to prepare for hemodialysis and access outcomes.
Starting RASi lowers KRT risk while maintaining similar cardiovascular risks as CCB in advanced CKD patients. This nationwide study suggests RASi may slow kidney disease progression and offer cardiovascular protection.
A study assessing US nephrology fellows' perceptions on home dialysis training found moderate preparedness for peritoneal dialysis and low confidence in home hemodialysis. The majority of trainees participated in continuity clinics and education, yet desired more focused teaching on PD and HHD.
Combination therapy of verinurad and febuxostat significantly lowers urinary albumin excretion and uric acid levels in people with chronic kidney disease and type 2 diabetes. The treatment is generally well-tolerated, with minimal adverse events reported.
Researchers analyzed 1,347 nephrectomy specimens to understand kidney histopathological findings. They found that more scarring in glomerulus, tubules/interstitium, and vessels is associated with worse kidney function.
Higher serum creatinine-to-cystatin C ratios are associated with lower mortality rates in patients initiating continuous renal replacement therapy for acute kidney injury. This simple tool may improve mortality risk assessment in critically ill patients developing AKI.
A study of US hospitals found that children with chronic kidney disease (CKD) experience longer hospital stays and incur higher healthcare expenses due to the complexity of their medical needs. Further investigation is needed to understand the healthcare needs of this population.
A study of 3,503 patients found beta blocker use reduced mortality by 21% among those starting dialysis. This association supports the routine use of beta blockers for heart failure patients initiating dialysis.
This study compares native arteriovenous fistula (AVF) patencies across countries, revealing significant variation in rates and predictors of long-term function. New AVFs that fail to mature successfully associate with increased mortality risk, emphasizing the need for individualized access selection and clinical pathways.
A recent study found that being physically active can significantly reduce the risk of developing chronic kidney disease (CKD). The study, which followed over 15,000 middle-aged adults for 24 years, showed that even moderate physical activity can lower the risk of CKD by up to 11%.
A cardiac biomarker was found to have stronger associations with kidney disease progression than blood pressure in both diabetic and nondiabetic individuals. Higher levels of NTproBNP, urine NGAL, and troponin T were linked to increased rates of CKD progression.
Obesity, as measured by body mass index and abdominal fat content, is associated with an increased risk of heart disease and progression of kidney disease in patients with chronic kidney disease. Lower physical fitness levels are also linked to a higher cardiovascular risk.
A study of 9,029 adults found that cystatin C-based kidney function was associated with lower odds of frailty, falls, and cardiovascular disease events. The difference between cystatin C- and creatinine-based kidney function could be used to predict adverse outcomes in older adults.
A decision support system within the EHR system significantly increased provider awareness of CKD among primary care providers. The study demonstrated that implementation of such a system can lead to improved processes of care, including blood pressure management and medication prescribing.