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Princeton University


Biologists track down central cause of lupus

Researchers at Princeton University have pinpointed what appears to be a central cause of lupus, an autoimmune disease that affects 1.4 million Americans. The discovery highlights a specific mechanism in B cells that produces disease-fighting antibodies, which can mistakenly attack the body's own DNA.

Mathematical analysis could aid flu vaccine selection

Researchers at Princeton University developed a mathematical method to predict the coming year's flu strain based on previous years' genetic sequences. The approach identified clusters of genetically similar viruses that tend to dominate in each season, with an accuracy rate comparable to existing methods.

SourcePrinceton University·JournalProceedings of the National Academy of Sciences·DateApr 22, 2002

Neuroscience contest prompts 'thinking about thinking'

A Princeton scientist created a computer model of a mouse brain that can recognize spoken words, challenging conventional views on sensory perception. The model uses sensitive timing of electrical signals to perform calculations, potentially leading to faster and more sophisticated brain functions.

SourcePrinceton University·JournalProceedings of the National Academy of Sciences·DateDec 13, 2000

Scientists create smart mouse

Researchers at Princeton University genetically modified mice to have improved learning and memory by adding a single gene, NR2B. The results show that the brain uses a common biochemical mechanism for forming associations, and this finding could lead to human gene therapy for dementia.

SourcePrinceton University·JournalNature·DateSep 2, 1999