Combining trastuzumab and ZD1839 has been shown to be more effective in inhibiting breast cancer cell growth than using either treatment alone. The findings suggest a potential new approach for treating multiple types of cancers, including those with HER2 and EGFR gene mutations.
Recent studies suggest that modulating glial inflammation may be an effective approach to delaying onset or slowing progression of neurodegeneration. New compounds described in a study selectively block production of IL-1B, iNOS and NO by activated glia without diminishing the production of other glial proteins.
A new combination of MabThera and standard chemotherapy has shown a significant increase in overall survival rate and complete remission rates in patients with aggressive non-Hodgkin's lymphoma. This treatment offers hope for improved outcomes in this increasingly common form of blood cancer.
Scientists at the University of Illinois have developed a family of fluorescent silicon nanoparticles in various sizes and colors, which can be used for electronic displays, flash memories, and biomedical imaging. The particles are photostable and bright, allowing for non-invasive detection and study of biological phenomena.
The study reveals the structure of edema factor, a toxin that causes fluid accumulation and disrupts immune function. The researchers found that calmodulin binds to edema factor, changing its shape and making it more potent, providing an ideal drug target for developing anti-anthrax drugs.
Researchers at Idaho National Laboratory are testing the effectiveness of ozone technology to sterilize mail by delivering high concentrations of ozone through potato conveyor belts. Preliminary results indicate that a 60-minute exposure to high levels of ozone inactivates anthrax spores, providing a potential tool against terrorism.
Researchers at UC Riverside have identified a chicken chemokine, cCAF, that plays a critical role in wound healing and may help accelerate the process in humans. The discovery has potential for treating wounds in diabetics, people with pressure ulcers, and those with bedsores.
Researchers discover antimicrobial peptides in plants and animals, which target bacterial membranes to defend against infections. The study reveals these molecules provide a natural solution to combat growing antibiotic resistance.
A Princeton University study reveals that South American forests offer a glimpse into pre-industrial US ecosystems, showing complex organic compounds as the main form of nitrogen in unpolluted ecosystems. The findings suggest that high levels of inorganic nitrogen in the US are mainly due to acid rain and agricultural fertilizers.
Researchers found that severe head injury survivors can learn implicitly, despite impaired explicit learning and memory. This discovery holds promise for new approaches to remediation for CHI survivors, who often struggle with cognitive impairments.
The Society for Women's Health Research has published proceedings from its Second Annual Conference on Sex and Gene Expression. The conference explored topics such as sex differences in embryonic development, cognitive functions, and mitochondrial DNA. Researchers from various backgrounds shared their findings contributing to the emerg...
Researchers found vitamin C prevents inhibition of gap-junction intercellular communication induced by hydrogen peroxide. However, quercetin in apples has even stronger anticancer activity than vitamin C.
Researchers have identified aquaporin-1 protein's role in regulating water movement into and out of cells, a fundamental requirement for life. In a study comparing normal lungs to those without the protein, scientists found increased airway wall thickness and fluid leakage in those with aquaporin-1.
A multi-center study led by Dr. Jay Iams found that home uterine monitoring has no clinical value in predicting early birth, despite its widespread use for high-risk women. The study's results reinforce previous findings that ambulatory monitors are not more effective than other diagnostic tools or surveillance programs.
A recent study published in the New England Journal of Medicine found that predicting preterm birth remains challenging due to low predictive value of current tests such as ultrasound and fetal fibronectin. The study suggests that prematurity in America is on the rise, with a 23% increase in premature births since the 1980s.
A recent study published in Hormone Research found that individuals born with a micropenis who were raised as males reported higher satisfaction rates and more positive body image compared to those raised female. The study also highlighted the importance of testosterone replacement therapy for male participants.