Research found that obese people who are metabolically healthy still face an increased risk of developing diabetes and cardiovascular disease. The study analyzed data from over 5,700 participants and found that normal weight individuals with multiple metabolic abnormalities also faced a higher risk of cardiovascular disease.
A study published by The Endocrine Society found that older men with optimal testosterone levels lived longer, while those with high or low levels had a higher mortality risk. Higher DHT levels were also associated with reduced ischemic heart disease mortality.
A new Clinical Practice Guideline recommends that all pregnant women with no prior diagnosis of diabetes be tested for the condition at their first prenatal visit. Early detection can help prevent complications and ensure a healthy pregnancy. The guideline also provides recommendations for testing, treatment, and follow-up care for wom...
A new testing approach can better detect parathyroid hormone imbalances in end-stage kidney disease patients, which are linked to higher mortality rates. The study found that patients with higher levels of non-oxidized parathyroid hormone had a lower risk of death.
A study found that older individuals with low thyroid hormone levels, particularly T3, have a higher risk of death from all causes and cardiovascular disease. The research suggests that thyroid hormone levels could be a useful predictor of survival rates in hospitalized elderly patients.
A recent study published in The Endocrine Society's journal refutes the long-held belief that a protein is necessary for producing steroid hormones like testosterone. Researchers found that male mice with a specific protein deficiency produced normal levels of testosterone, challenging the existing scientific understanding.
The Endocrine Society publishes a Clinical Practice Guideline for diagnosing and treating polycystic ovary syndrome (PCOS), a leading cause of infertility in women. The guideline provides clear criteria for diagnosis and treatment recommendations, aiming to address the complexities of this hormone disorder.
A recent study found a modest connection between low testosterone and an increased risk of developing or dying from heart disease. However, treating low testosterone with hormone replacement therapy did not have any beneficial effect on cardiovascular health.
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that vitamin D supplements do not reduce bone turnover or protect bone health in postmenopausal women. In contrast, calcium supplements significantly reduced bone turnover and decreased the risk of osteoporosis.
A recent study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that young women are better equipped to deal with the negative effects of insulin resistance. This biological ability may explain why women typically develop heart disease 10 years later than men.
Researchers developed an animal model simulating eye complications associated with Graves' disease, paving the way for better treatments. The condition causes the thyroid gland to become overactive and produce too much thyroid hormone, leading to eye problems like swelling of tissue behind the eyes causing them to bulge outward.
A recent study found that intensive lifestyle changes and metformin treatment reduced cholesterol levels and improved triglyceride profiles, lowering the risk of heart disease. The Diabetes Prevention Program analyzed over 1,600 participants, showing positive changes in blood particle distribution.
A recent study found that reduced levels of inflammation may explain how some obese individuals remain metabolically healthy. Inflammation is associated with a higher risk of diabetes and heart disease, but some obese people do not develop high blood pressure or unfavorable cholesterol profiles.
A recent study found that glucagon, a hormone involved in regulating appetite, fails to induce feelings of fullness in obese individuals. However, it successfully suppresses hunger pangs in people with type 1 diabetes, according to researchers from The Endocrine Society.
A recent study found a strong association between gestational diabetes and sleep apnea in pregnant women. Women with gestational diabetes lost an hour of sleep each night, increasing their risk for stroke, cardiovascular disease and heart attacks.
Research links perfluorinated chemical (PFC) exposure to changes in thyroid function, particularly in women, with elevated levels of T3 and T4 hormones. PFCs found in various products may increase the risk of mild hypothyroidism without triggering a natural hormonal response.
A recent study found that vitamin D-deficient older individuals are more likely to struggle with everyday tasks and experience physical decline. The researchers suggest that vitamin D supplementation could help prevent these issues, but further studies are needed to confirm the findings.
Researchers developed a new risk assessment scoring system that better identifies high-risk adults, especially African Americans, for developing type 2 diabetes and heart disease. The scoring system considers sex and racial-ethnic differences, leading to earlier prevention and treatment.
A multicenter European study found that short-term hormonal therapy for transsexualism is effective and safe, with few side effects. The treatment, which involves large doses of male or female sex hormones, was shown to be effective in changing the external characteristics of trans individuals.
Researchers found that taking calcium before exercise results in less of a decrease in blood calcium levels and slightly lower parathyroid hormone levels compared to taking it after exercising. This could help maintain stable blood levels during exercise and potentially mitigate bone loss.
A meta-analysis study found that insulin degludec has a similar or reduced risk of recurrent hypoglycemia compared to insulin glargine. The study, involving nearly 3,400 adults with type 2 diabetes, suggests that insulin degludec may offer benefits in reducing the major side effect of insulin therapy.
A large study found similar genetic variations in overweight newborns and obese adults, suggesting a common genetic background. This discovery may lead to earlier identification of high-risk newborns and interventions to prevent obesity later in life.
Research suggests prenatal BPA exposure causes increased inflammation in fat tissues after birth, leading to obesity and metabolic syndrome. The study found that prenatal BPA exposure interacts with postnatal diet to modulate inflammatory mechanisms in fat deposits.
A new study in mice finds that low testosterone worsens obesity-related brain damage, increasing the risk of type 2 diabetes and Alzheimer's disease. Obese mice with low testosterone showed more body fat, higher blood sugar levels, and poorer glucose tolerance than those with normal testosterone.
A study found that patients taking tasimelteon had a significantly higher rate of re-synchronization of their body clock, leading to improved night-time sleep and reduced daytime drowsiness. The medication addresses the root cause of Non-24 Hour Sleep-Wake Disorder in blind individuals by synchronizing their circadian clock.
A new study by The Endocrine Society finds that early exposure to BPA significantly increases the risk of both prostate cancer and a precancerous condition known as prostate epithelial neoplasia. The study used human prostate stem cells from organ donors to grow prostate tissue in a mouse model.
A new study published in The Endocrine Society's Annual Meeting found that testosterone therapy improved verbal learning and memory in postmenopausal women compared to placebo. Testosterone levels increased with treatment but remained within normal female range, with no major side effects reported.
Researchers identified a key brain enzyme, prohormone convertase 2 (PC2), involved in opioid addiction. PC2 regulates endogenous opioids in the brain, leading to increased mu opioid receptor expression.
A new study suggests that testosterone therapy can reduce pain perception and tolerance in men with low testosterone levels caused by opioid pain relievers. The study found significant improvements in pain sensitivity during laboratory pain testing after testosterone administration compared to placebo.
A high-fat diet in pregnant monkeys resulted in permanently changed brain cells controlling food intake, leading to increased body weight and preference for fatty foods in their offspring. This study suggests a potential long-term impact on human health.
A new drug called pyrvinium pamoate inhibits aggressive prostate cancer resistant to standard drugs by binding to a different site on the AR and inhibiting its activity without preventing androgen binding. This unique mechanism of action has the potential to treat cancers resistant to currently approved therapies.
Researchers found that vitamin D deficiency is linked to early onset of puberty in girls, with 44% having severe deficiencies. Vitamin D supplementation may help delay pubertal onset and progression.
A new study found a link between fetal exposure to bisphenol A (BPA) and lower levels of insulin-like peptide 3, a key testicular hormone. This could be a co-factor in the development of cryptorchidism, a common birth defect in boys.
A clinical study found that kisspeptin effectively induces egg maturation in women undergoing IVF treatment, reducing the risk of ovarian hyperstimulation syndrome. The hormone triggers natural reproductive hormone release, resulting in healthy babies.
A new study finds desiccated thyroid extract (DTE) to be a safe and effective alternative to standard T4 therapy for hypothyroid patients. DTE caused modest weight loss and nearly half of the study patients preferred it over L-T4.
A new study has found that the directed in vitro technique, ICSI, may increase the risk of insulin resistance among children. The study used metabolomics to assess the risk of developing obesity and metabolic syndrome, finding significant differences in 38 metabolites between ICSI and non-ICSI conceived children.
A study found that combining metformin and liraglutide results in greater weight loss and improvements in body mass index and waist circumference for women with polycystic ovary syndrome. This combination therapy also leads to higher chances of conception, improved pregnancy outcomes and improved metabolic profile.
A study found that exposure to triclocarban during lactation in rats can affect the early development of their offspring. The researchers found that pups exposed to triclocarban were significantly lighter and had a lower survival rate compared to those not exposed.
A new drug has been found to increase the amount of energy burned by fat tissue, leading to significant weight loss and improved metabolic health. The drug, GC-1, mimics the activity of thyroid hormone and has been shown to promote thermogenesis in white adipose tissue.
A new animal study finds that short-term use of antidepressants, combined with stress and a high-fat diet, leads to long-term increases in body weight. The study suggests that the medication, rather than the diet alone, contributes to the weight gain, which is accompanied by increased bone and spleen weights.
A clinical study found that insulin resistance is associated with weakened bones and a higher risk of bone fractures. The study, presented at The Endocrine Society's annual meeting, showed that bone strength decreased by 10-14% for every doubling of insulin resistance.
A clinical study found that high-dose testosterone significantly improves sexual function among women who have had their uterus and ovaries removed. Women receiving 25mg of testosterone experienced improved blood concentrations of free testosterone, related to increased sexual encounters.
A new study has found that skipping breakfast can lead to acute insulin resistance in overweight women, a condition that increases the risk of developing type 2 diabetes. After just one day of skipping breakfast, insulin levels were significantly higher and glucose levels more elevated than after eating breakfast.
A new study in mice found that fathers' diets before conception impact their offspring's body weight and fat content. Male offspring of paternal mice with diet-induced obesity had higher body weight and increased body fat compared to control mice.
A new study suggests that vitamin D deficiency may play a role in the increased allergy and asthma risk in overweight and obese adolescents. Researchers found significant correlations between the severity of obesity, adipokine levels, and biochemical measures of allergic disease.
A new clinical trial shows that whole body vibration therapy increases bone-mineral density and muscle mass in adolescents with cerebral palsy, allowing for improved walking ability and overall health. The therapy significantly enhances leg and spine bone-mineral density, while also increasing muscle mass in the legs.
A new study found that participants who received the dietary supplement Juven experienced significant increases in lean body mass, while those who received a placebo did not. Blood concentrations of IGF-1 also increased among Juven recipients, but the correlation with improved muscle mass was not statistically significant.
Researchers discovered a molecular switch, Steroidogenic Factor 1, that stimulates steroid hormone production and cell multiplication in aggressive prostate cancers. This factor increases tumor growth and resistance to hormone treatment.
A study shows that bazedoxifene, an approved osteoporosis drug, inhibits estrogen-induced gene expression and cell proliferation in breast cancer cells. The medication also reduced estrogen activity and estrogen receptor levels in cultured human breast cancer cells.
A new study published by The Endocrine Society found that weight loss improves memory function in older, overweight women. After six months of dieting, their brain activity changed in the regions important for memory tasks, with improved performance and altered brain activity detected.