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Wiley


Vascular risk linked to long-term antiepileptic drug therapy

Researchers found that patients with epilepsy on long-term antiepileptic drugs, especially phenytoin, carbamazepine, and valproic acid, are at increased risk for developing atherosclerosis. The study suggests that newer AEDs like lamotrigine may minimize metabolic disturbances and reduce this risk.

SourceWiley·JournalEpilepsia·DateNov 15, 2011

Poor sleep habits linked to increased risk of fibromyalgia in women

A longitudinal study published in Arthritis & Rheumatism found a strong association between poor sleep habits and the risk of developing fibromyalgia in women. The study, which followed over 12,000 women for ten years, found that women with severe sleep problems were at increased risk of developing fibromyalgia.

SourceWiley·JournalArthritis & Rheumatism·DateNov 14, 2011

Adolescent alcohol consumption and breast cancer

A new study found a significant association between adolescent alcohol consumption and increased risk of benign breast disease among girls with a family history of breast cancer. Consuming more alcohol was linked to a higher risk, particularly in those with rapid height growth spurts.

SourceWiley·JournalCancer·DateNov 14, 2011

Secluding aggressive young offenders is always the last resort says 4-country study

A four-country study published in the Journal of Psychiatric and Mental Health Nursing found that verbal intervention was the favoured technique for dealing with aggressive episodes involving young offenders. The research team also recommended continuous education, sufficient resources, and further studies to improve practices.

SourceWiley·JournalJournal of Psychiatric and Mental Health Nursing·DateNov 3, 2011

Successful pregnancy possible after kidney transplant

A new study published in the American Journal of Transplantation reveals that women who undergo a kidney transplant can successfully carry a pregnancy with a live birth rate of 73.5%. However, pregnancy complications such as preeclampsia and preterm delivery are common, especially among those pregnant within two years of the transplant.

SourceWiley·JournalAmerican Journal of Transplantation·DateOct 20, 2011

How learning more about mass nesting can help conserve sea turtles

Researchers have gained insights into the synchronised mass nesting of female olive ridley sea turtles, shedding light on their reproductive behaviour and population dynamics. The study's findings suggest that this small population in French Guiana has increased its nest number three-fold over the past decade, but also makes them more ...

SourceWiley·JournalJournal of Animal Ecology·DateOct 18, 2011

Miscarriage diagnosis guidelines questioned

Research published in Ultrasound in Obstetrics and Gynecology found that current definitions for miscarriage diagnosis can lead to incorrect diagnoses. The studies also revealed a 20% variation in gestational sac sizes reported by different clinicians, which can cause false conclusions about pregnancy growth.

SourceWiley·JournalUltrasound in Obstetrics and Gynecology·DateOct 13, 2011

Drug prevents bone loss side effects of breast cancer medication

A new study has found that zoledronic acid can prevent and treat bone loss in postmenopausal breast cancer patients taking aromatase inhibitors. The five-year study showed significant increases in bone density when the drug was administered upfront, but also found that initiating treatment even after bone loss developed was beneficial.

SourceWiley·JournalCancer·DateOct 10, 2011

Neural stem cell transplant may tackle diabetes

Researchers have discovered a method to harness patient-derived neural stem cells as an alternative source of insulin-producing beta cells for regenerative treatments. This breakthrough could potentially overcome the shortage of donor pancreatic beta cells and provide a safer, more accessible way to treat diabetes.

SourceWiley·JournalEMBO Molecular Medicine·DateOct 6, 2011

Frequently used weight-loss method is light on evidence

A newly published Cochrane systematic review reveals that the transtheoretical model stages of change (TTM SOC) method is ineffective in achieving significant weight loss. The study found that TTM SOC resulted in only 2kg or less weight loss, and no conclusive evidence of sustained weight loss was observed.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateOct 4, 2011

Culling can't save the Tasmanian devil

A new study suggests that culling Tasmanian devils cannot control the spread of facial tumour disease and may even increase its transmission. Alternative strategies such as setting up insurance populations, finding genetic resistance, and developing a vaccine are being explored to save the iconic marsupial

SourceWiley·JournalJournal of Applied Ecology·DateOct 4, 2011

Alcohol-related behavior changes -- blame your immune system

A new study found that blocking Toll-like receptors reduces the effects of alcohol on the brain, which could lead to treatments for alcohol dependence and acute overdoses. This shift in understanding may help identify individuals at risk of brain damage after long-term drinking.

SourceWiley·JournalBritish Journal of Pharmacology·DateSep 28, 2011

End-of-life discussions do not affect survival rates, study shows

A new study published in Journal of Hospital Medicine found that discussing end-of-life care with physicians does not affect survival rates. Patients who have advance directives in their medical records also have similar survival rates as those without these discussions and documents.

SourceWiley·JournalJournal of Hospital Medicine·DateSep 28, 2011