A $6.5 million nanomedicine center at Yale University aims to design, model, synthesize, and fabricate nanomedical devices based on natural and synthetic ion transporters. The center will focus on developing biobatteries for implantable devices, including an artificial retina.
Peter A. Raymond, Yale assistant professor of ecosystem ecology, has received the 2005 Cronin Award for his research on rivers, estuaries, and coastal systems' role in carbon budgets. He studies climate and land use's impact on river carbon transfer and collaboration with researchers on air-water CO2 exchange.
Researchers at Yale have identified a genetic link to Tourette's Syndrome in a rare DNA sequence mutation. The study found an abnormal DNA sequence in one family and identical, very rare changes in two unrelated individuals, suggesting the gene plays a role in regulating gene expression through microRNAs.
Researchers found that hypothermia significantly reduced brain injury and death from oxygen loss in newborns. The study, led by Seetha Shankaran, M.D., at Wayne State University, showed a 44% lower rate of moderate to severe disability or death in infants treated with cooling compared to those in the control group.
The incidence of preterm birth and low birthweight infants are pressing obstetrical issues, according to Michael Paidas. He emphasized the need for risk assessment with fetal fibronectin and cervical length to prevent adverse pregnancy outcomes.
Researchers at Yale University found innovative approaches to ensuring rapid treatment of patients, including management techniques and flow charts. The study identified key success factors for improving quality care in hospitals, with a focus on proper organization, planning, and communication.
Researchers at Yale School of Medicine found that expanded physician and residency training in telephone medicine is necessary to prevent medical mishaps. The lack of visual cues indicating emotions may lead physicians to assume patients take news better than they actually do.
A community-level intervention program targeting young adolescents delays early intercourse, increases condom use, and reduces high-risk sexual behavior. The program successfully delayed sexual debut and increased condom use among participants.
This study shows that expressed attitudes can be modified by providing consensus information about the beliefs of others. The researchers found that a peer group's influence is more significant than a non-associated group in shaping attitudes towards obesity.
Researchers at Yale University found that myelin physically limits axonal growth and regeneration after traumatic injury. Blocking vision in one eye normally alters ocular dominance only during critical development, but mutations in the Nogo-66 receptor affect abnormal plasticity later in life.
T.P. Ma, Yale University professor, receives IEEE Andrew S. Grove Award for his pioneering work on CMOS gate dielectrics, a crucial technology in modern silicon chips. He has made significant contributions to increasing integrated circuit operating speed and reliability while lowering cost per function.
The MRSEC research program will focus on oxide materials and their interfaces, exploring new electronic, magnetic, and chemical behavior. The Center aims to increase diversity in STEM fields and provide educational opportunities for students of all levels.
A Yale University team has confirmed the existence and location of the long-speculated Maya city Site Q in Guatemala. The discovery was made by Marcello Canuto's team, who found an in-situ panel carved with over 140 hieroglyphs that match the style and historical chronology of the Site Q texts.
A study published by Yale University scientists analyzed the genetics of quagga and plains zebra populations to understand how the quagga evolved its distinctive stripes. The research found that the quagga diverged from Plains zebra around 120,000-290,000 years ago during the Ice Age.
A study by Yale researchers found that a combination of platinum-based chemotherapy and vaginal radiation significantly reduces the recurrence of uterine papillary serous carcinoma (UPSC). The procedure increases survival rates among women with this aggressive form of uterine cancer, which affects about seven percent of new cases at Yale.
In rats with spinal cord injury, third order neurons in the thalamus abnormally fire signals without incoming stimuli. Targeted molecular agents suppress these rogue neurons' activity, reducing phantom pain.
Researchers at Yale University have developed two ways to induce MS symptoms in mice, revealing a key distinction between disease-causing and non-disease antibodies. The study brings the team closer to pinpointing accurate diagnostic tools for individual MS patients.
A recent study by Yale University researchers has discovered a gene that controls the severity of asthma, finding that high production variants of the macrophage migration inhibitory factor (MIF) gene are associated with severe disease. The study used mice models and human data to support an important role for MIF in asthma pathogenesis.
A study published in Nature Neuroscience reveals that AgRP neurons play a crucial role in regulating eating behavior and body weight. The research found that these neurons are essential for acute regulation of eating, and their destruction leads to anorexia and changes in blood glucose levels.
A new Yale study reconciles two long-standing models of schizophrenia: the dopamine hypothesis and the PCP Model. Researchers found that drugs like ketamine, which block glutamate receptors, produce a more complete schizophrenia-like state than amphetamine.
Researchers found that MXC alters estrogen-regulated gene Hoxa10 in the reproductive tract, reducing embryo implantation ability. Exposure to MXC has been shown to induce abnormalities in female reproductive tract development and function.
A study by Yale University researchers found that most embryos produced during IVF do not result in live births. The study aimed to identify methods for screening viable embryos and improve egg production techniques.
Research by Yale University scientists reveals GABA's role in regulating neural stem cells. The study suggests that enhancing GABA's function may limit neurogenesis and increase the risk of glioma, a type of brain tumor.
A multi-center clinical trial found that an oral contraceptive containing drospirenone was effective in improving productivity, enjoyment of hobbies, and social activities among women with PMDD. The study showed that the low-dose oral contraceptive was roughly as effective as serotonin reuptake inhibitors in reducing symptoms.
A new study published in Psychopharmacology suggests repeated nicotine exposure can increase motivation for food weeks after the last exposure, counteracting its appetite-suppressant effect. This finding has significant implications for smoking cessation and weight gain concerns.
The study reveals inhibitory systems play a crucial role in controlling the timing of action potentials and network synchronization. This fine-tuning affects cognitive functions and may underlie problems in psychiatric disorders like schizophrenia.
New study finds that women and black patients with a heart attack are less likely to receive recommended treatments, including aspirin and reperfusion therapy. The researchers also found that cardiac catheterization was used less frequently in these patient groups.
A Yale University study found that early use of hormone therapy is linked to fewer wrinkles and firmer skin. The researchers compared 11 non-users with nine long-term hormone therapy users and found significant decreases in wrinkle severity and rigidity.
Researchers at Yale University have identified a potential new target for treating vascular disease by inhibiting the protein kinase Akt1. The study found that Akt1 plays a crucial role in the formation of new blood vessels, which is essential for improving blood flow to muscles during exercise.
Research by Yale University found that insulin-resistant individuals' mitochondria produce less ATP, a key energy molecule. This defect may explain the link between inherited type 2 diabetes risk and reduced insulin signaling.
Researchers from Yale University and the Imperial College have digitally reconstructed a fossilized brachiopod complete with its pedicle and lophophore, revealing new insights into extinct forms. The discovery sheds light on the evolution of brachiopods and challenges previous assumptions about their similarities to modern examples.
A team of biologists has discovered that plumed feather structures involve the coordination of at least two genes that activate and inhibit barb growth. This finding provides the best experimental evidence for a classical theory of growth in complex biological structures.
A study by Yale University researchers found that delayed treatment for heart attacks treated outside regular hours leads to increased mortality rates. PCI therapy, which opens narrowed coronary arteries, is more effective when administered promptly, but delays result in reduced survival benefits.
Dr. Holford's research focuses on applying statistical methods to public health and medicine, analyzing disease trends and developing strategies for controlling cancer. He was recognized as a fellow of the ASA, one of only 0.33% of members elected each year.
Researchers aim to investigate whether starting hormone therapy early can prevent atherosclerosis and heart attacks. The KEEPS trial, led by Yale University, seeks healthy women aged 42-58 for a double-blind study exploring the effects of early menopausal hormone therapy.
A new database, The Canary Database, tracks animal diseases linked to human health threats, such as mercury poisoning and West Nile Virus infection. The project aims to improve human health decision-making by analyzing animal sentinel data.
A Yale University study will examine dietary calcium insufficiency in inner city infants, highlighting the alarming trends of decreased calcium intake over the past 30 years. The research aims to establish guidelines for calcium in infants below age three and predict a 10-20% prevalence of abnormal biomarkers.
A Yale University study found that drinking alcohol may lower the risk of non-Hodgkin's lymphoma, particularly for Burkitt's lymphoma subtype. The study analyzed data from 15,175 individuals and found no significant association between age, sex, family history, or cigarette smoking with reduced risk.
A collaborative project developed a way to study the function of genes in mice and humans using a moveable genetic element from moths. The technique, called piggyBac, allows for efficient genetic manipulation in vertebrates and mammals, enabling researchers to systematically understand the functions of mammalian genes.
A study by Yale University and NOAA finds that direct sunlight affects weather balloon temperature probes, leading to discrepancies in global warming estimates. This correction reveals an increase of 0.2 degrees Celsius per decade in average global temperature over the last thirty years.
Researchers at Yale and Cold Spring Harbor Laboratory have identified 80 genes active in petal and stamen development using gene trapping. These findings provide insights into how gene activity is allocated during flower development, shedding light on critical roles in plant reproduction like cross-pollination and seed production.
Researchers at Yale University have found that varying oxygen concentrations in alligator eggs alter growth patterns and affect bone development, suggesting a link to fossil records of prehistoric atmospheric oxygen levels. The study provides new insights into the complex interaction between vertebrate development and oxygen levels.
Researchers found that riluzole, a glutamate modulating agent, reduced symptoms in 35% of patients with OCD. The study suggests that riluzole may represent a novel treatment intervention for certain anxiety and mood disorders.
Researchers at Yale University discovered that male birds produce unique songs by rubbing their wings together. The wing song is as loud as a typical bird vocal and can be heard tens of meters away. This unusual behavior supports the theory that sounds made by feathers evolved through sexual selection.
A team of scientists led by Michael Russello has discovered a new taxon of Galápagos tortoise, characterized by distinct genetic features. The discovery highlights the importance of accurate taxonomy for effective conservation policy and preservation of genetic diversity in these endangered species.
A study found that hospitalised older patients with delirium had a 13% shorter lifespan compared to those without delirium. The researchers estimate that this equates to approximately one year of life lost per patient.
Research reveals that high TRAIL-R2 expression in breast cancer patients is associated with poorer survival outcomes. The AQUA TM system was used to analyze tissue microarray specimens and identify correlations between receptor expression levels and clinical variables.
This special issue examines the role of consumption in shaping the environment, exploring its impact on water use, energy consumption, and product life spans. Researchers analyze household and global consumption patterns to better understand the pivotal role of consumption in environmental management.
Researchers at Yale University have identified unique infrared laser spectrum signatures for free protons associated with one to three water molecules. The study reveals that the proton's vibrations are driven by changes in its hydration environment, leading to significant shifts in spectral signatures.
A study published by Yale researchers found that 17 members of a family carried a specific mutation in the sodium channel Nav1.7 gene, which is associated with intense burning pain in the hands and feet triggered by heat and exercise. The discovery suggests the possibility of rational therapies targeting this affected channel.