A new tool, INSPECT-SR, has been developed to assess the trustworthiness of randomized controlled trials (RCTs) and identify problematic studies. This tool, which has been endorsed by the Cochrane community, provides a rigorous and transparent method for reviewers to evaluate the integrity of trial data.
The ASPIRE trial aims to enroll 1,200 participants with advanced prostate cancer and assess the impact of chemotherapy on overall survival and disease progression. Genetic profiling is included to identify patients who benefit most from intensified treatment.
Researchers found evidence of Native American dice making and use dating back 12,000 years, with binary lots crafted from bone featuring markings for counting sides. This discovery challenges traditional views on the origins of probability theory.
A new clinical trial will investigate whether adding the oral medication vorasidenib to standard chemotherapy improves progression-free survival for people with newly-diagnosed, grade 3 IDH-mutant astrocytoma. The study aims to recruit 400 individuals with this type of brain cancer and evaluate the safety and side-effect profile of the...
Princeton Chemist Salvatore Torquato and astrophysicist Oliver Philcox applied statistical mechanics to find similarities in galaxy distribution across length scales. They used new descriptors to characterize structural data, revealing a correlated disorder in the spatial relationships between galaxies.
A new key review by Gotelli and McGill provides an overview of the current status of neutral models in ecology, highlighting their role relative to older ecological models. The paper demonstrates parallels in theory development between neutral models and null models, shedding light on community patterns and species interactions.