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ATP-binding cassette transporter defects and their roles in hepatic diseases

ABCA–ABCG transporters play a crucial role in biliary secretion, with mutations leading to various hepatobiliary disorders. Next-generation genetic testing enables tailored management, while emerging therapies hold promise for cholestatic diseases. Genetic counseling is recommended for family planning and risk assessment.

SourceXia & He Publishing Inc.·JournalJournal of Clinical and Translational Hepatology·DateJan 28, 2026

Common eye ointment can damage glaucoma implants, study warns

A new study from Nagoya University in Japan has found that petrolatum-based eye ointments can cause MicroShunt glaucoma implants to swell and potentially rupture. The study suggests that clinicians should avoid using these ointments on patients with the implant, particularly when it is exposed outside the conjunctiva.

SourceNagoya University·JournalGraefe s Archive for Clinical and Experimental Ophthalmology·DateJan 13, 2026

Clinical characteristics and outcomes of portal vein thrombosis in patients with porto-sinusoidal vascular disease

A study of 169 patients with porto-sinusoidal vascular disease found that portal vein thrombosis was associated with higher rates of esophageal variceal bleeding, ascites, and antithrombin III deficiency. The study also reported a higher risk of mortality in patients with PVT compared to those without.

SourceXia & He Publishing Inc.·JournalJournal of Clinical and Translational Hepatology·DateNov 11, 2025

Fats help tag medical implants as friend or foe

Researchers discovered that lipid deposition on medical implant surfaces can signal to the immune system whether to attack or ignore the implant. This knowledge could help develop biomaterials that deflect host immune aggression, reducing malfunction rates for devices like pacemakers and surgical mesh.

SourceRice University·JournalAdvanced Materials·TypeExperimental study·DateMar 14, 2023

Surgeons refine procedure for life-threatening congenital heart defect

Researchers analyzed 43 patients with hypoplastic left heart syndrome (HLHS) who underwent either an arterial or venous shunt as part of the hybrid palliation procedure. The study found that the arterial shunt group showed better pulmonary arterial growth, shorter surgical times, and higher oxygen saturations at discharge. However, no ...

SourceAmerican Association for Thoracic Surgery·JournalJournal of Thoracic and Cardiovascular Surgery·DateAug 13, 2015