Research on treating disease with medication. Covers psychedelics, combination cancer therapy, opioid treatment in pregnancy, and personalized guidelines.
Researchers have discovered a way to quickly determine if women with advanced breast cancer are responding to hormone therapy using positron emission tomography (PET). The finding could reduce the need for harsher chemotherapy and improve quality of life for patients.
A new study by Thomas Jefferson University finds that traditional criteria for stroke-preventing surgery may overestimate men's risk and underestimate women's risk due to smaller carotid arteries. The 70% blockage threshold may need to be adjusted to account for these differences.
A study found that only 5% of rural adults seeking treatment for illegal drug use have adequate resources. Rural drug users often hesitate due to cost, lack of insurance, and concerns about maintaining anonymity at treatment centers. This gap highlights the need for targeted interventions in rural areas.
A study found that HIV remains in a dormant state within CD4+ lymphocytes even after treatment with triple-drug cocktail therapy. This persistence suggests individuals must continue multiple-drug therapy to prevent reactivation of the infection.
A study found that women, minorities, elderly, and those with severe heart attacks are less likely to receive clot-busting drugs and other medical procedures. Strong regional variations were also observed in the use of these therapies.
The study reveals a family of selenium-based compounds that can lower blood pressure without toxic side effects. These compounds could lead to the development of new therapeutic agents, expanding knowledge on selenium's role in human health.
A Duke University Medical Center study of patients from 57 hospitals found that treating a heart attack with direct angioplasty fails to save substantially more lives than therapy with clot-busting drugs. The rate of death or second heart attack was not statistically different between the two therapies.
Researchers found that estrogen replacement therapy accelerated wound healing in elderly postmenopausal women, outperforming those not on hormone therapy. The study suggests that hormone replacement therapy may benefit chronic wounds in older patients.
Targeted alpha-particle therapy using Bismuth-213 has shown very encouraging results in leukemia patients, with no significant uptake outside the target areas. The therapy appears safe and feasible, with high linear energy transfer and reduced damage to normal tissue.
The MiCK assay measures how light scatters off of leukemia cells to determine the effectiveness of drugs being used to attack the cells. This technique allows for more accurate identification of which drugs will be most effective for each patient, revolutionizing leukemia therapy.
Scientists at Case Western Reserve University have created artificial human chromosomes, offering a powerful tool for studying human genetics and potentially treating genetic diseases. The synthetic microchromosomes demonstrate normal centromeric activity, genetic stability, and continued gene expression.
A long-term trial found that treating hypertension reduces heart failure risk, even in those with severe heart disease. The study showed significant benefits for patients over 80 and those who had a heart attack before the trial.
A three-step program has been shown to keep drug offenders cleaner and out of prison, with graduates staying straight longer than those who received no treatment. The study compared prisoners who completed a prison-based treatment program with those who participated in a community-based program.
A new study shows that giving the drug for a longer period can significantly improve recovery over the standard treatment. About 60% of patients treated with 48-hour methylprednisolone starting at three to eight hours recovered a substantial degree of independence.
The Cook GR II Coronary Stent has received FDA clearance for treatment of acute or threatened vessel closure in patients with failed interventional therapy. The stent features a flat metal design and low profile for improved radial strength and trackability.
Only 36% of the U.S. population would have access to this therapy, with regions including rural areas and distant locations having limited emergency access. Researchers found that increasing treatment availability through helicopter transport could extend the treatment radius to 200 miles, benefiting up to 95% of the nation's population.
A study found that only 39% of stroke patients and 27% of the general population could identify a single warning sign of stroke, highlighting a need for education on recognizing symptoms and risk factors. The researchers also noted that controllable risk factors such as high blood pressure are not being adequately addressed.
The National Institute on Alcohol Abuse and Alcoholism's Project MATCH trial found one confirmed match between low psychiatric severity patients and 12-step facilitation therapy, showing improved abstinent days and decreased drinks per day
Researchers found that patients who received chemotherapy and radiation after surgery lived longer than those who did not. Additionally, 7% of patients had inherited mutations in the BRCA2 gene, which is linked to breast and ovarian cancer.
A University of Washington study found no significant difference in mortality rates between patients treated with anti-clotting drugs or balloon angioplasty after a heart attack. The study compared over 3,000 patients and showed that medical costs were lower for those treated with thrombolytic therapy.
A very low protein diet with amino acid supplements has been shown to cure severe kidney disease in some individuals. The study suggests that this dietary therapy should be tried before drug treatment for nephrotic syndrome, which often leads to kidney failure.
A Duke University study of 934 patients found that those treated with bypass surgery or angioplasty had better long-term survival rates compared to medication alone. Patients who underwent revascularization showed a significant increase in three-year survival rates, with bypass surgery resulting in the greatest percentage of survivors.