Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
Research found that green tea supplements can reduce facial dysmorphology in children with Down syndrome, especially when administered during the first three years of life. The study also suggests that high doses may disrupt facial and bone development, highlighting the need for further research and caution.
A combination of deep brain stimulation and exercise has potential benefits for treating ataxia by rescuing limb coordination and stepping. The study reports that stimulating mice with early-stage ataxia showed the most dramatic improvements, suggesting that early treatment may provide the biggest benefit for patients.
Researchers found significant changes in patients' personality profiles after effective anxiety therapy, scoring lower on neuroticism and becoming more extroverted. Metacognitive therapy produced the greatest effect on both symptoms and personality.
Research suggests that cognitive behavioral therapy (CBT) can help unemployed individuals find a new job or transition to full-time work within 16 weeks. The treatment also improves productivity and reduces negative beliefs associated with depression.
Researchers found that delayed treatment improved surgical outcomes and reduced complications for facial bone injuries. The 'Critical Revascularization Period' allows for healing and formation of new blood vessels, improving oxygen supply and reducing morbidity.
A large-scale study from Lund University found that psychotherapy for panic disorder produces lasting improvements in symptoms and quality of life. Two years after treatment, 70% of patients were clearly improved and 45% were remitted.
A new analysis published in The Lancet Psychiatry found that current psychological therapies for treating anorexia nervosa do not significantly differ from expert treatment as usual. This highlights the need for further research into more targeted therapies to improve patient outcomes.
Research from Charité - Universitätsmedizin Berlin shows that dispatch of mobile stroke units is linked to improved survival and reduced risk of disability. STEMOs enable timely thrombolysis and treatment, leading to better functional outcomes for patients.
Global wastewater treatment rates have improved to about half, but developing countries still lag far behind. The study highlights the need for increased financial resources and creative reuse opportunities to improve wastewater treatment practices.
Researchers at the University of Cambridge have developed a new method called Multi-Organoid Patterning and Fusion (MOrPF) to grow miniature versions of organs. The technique enables faster assembly of organoids into airway tubes with uninterrupted passageways, retaining their shape even in the absence of external support.
A sequential approach to treating comorbid PTSD and major depressive disorder has shown promising results in a randomized control trial. The study found that combining Cognitive Processing Therapy (CPT) and Behavioral Activation Therapy (BA) led to meaningful reductions in PTSD and depression severity.
A study by Beth Israel Deaconess Medical Center and Brigham and Women's Hospital found that ECMO therapy reduced mortality by 45% among critically ill COVID-19 patients. The analysis of over 5,000 patients revealed that those treated with ECMO had better odds of survival than those who were not treated.
Researchers have identified stable antimicrobial peptides as a potential solution to address citrus greening, a major threat to the global citrus industry. Multiple SAMP injections into infected trees increased tree growth, reduced bacterial levels and prevented disease symptoms.
Vertebral fractures often remain undetected despite their significance as risk factors for future fractures. Routine use of VFA in fracture liaison services helps physicians detect unrecognized fractures and inform treatment decisions. The IOF position paper emphasizes the potential of improved detection of vertebral fractures within FLS.
A new study by University of Texas at Austin researchers has found that trauma-focused psychotherapy reduces brain communication between emotion and logic regions, promoting symptom recovery. The study's findings suggest this restructuring of brain connections may be a key signature of PTSD recovery.
Researchers found that adolescent borderline pathology can improve with treatment, challenging previous assumptions about its intractability. The study of 500 adolescent patients over 18 months showed a significant downward trend of BPD features despite not undergoing specialized treatment.
A recent study from the University of Pennsylvania School of Nursing analyzed various dietary approaches and clinical trials to better understand how to optimize adherence and subsequent weight reduction. The findings suggest that there is not convincing evidence that one diet is universally easier to adhere to than another, highlighti...
ADG2 demonstrates comparable or higher neutralization potency against SARS-CoV-2 than leading antibodies in development for COVID-19. It binds effectively to all commonly circulating SARS-CoV-2 variants and shows broad neutralizing activity against SARS-CoV and related coronaviruses.
Researchers explore ECMO and CRRT treatment in critically ill SARS-CoV-2 pneumonia patients, achieving a 100% survival rate for those with cardiopulmonary failure. The combined therapy is deemed an important treatment technique for critically ill patients.
Researchers developed a new heat-based treatment that eliminates pathogens without harming plants, using a two-step process involving conditioning and lethal temperatures. This method reduces phytotoxicity and dispersal of pathogens, increasing fruit quality and yield while minimizing pesticide applications.
Researchers have found a compound isolated from the leaves of Inula viscosa that can kill brain-eating amoebae by causing them to undergo cell suicide. The compound, inuloxin A, has shown promise in lab studies and may be more effective than current treatments at crossing the blood-brain barrier.
A new report warns of significant increases in osteoporosis patients and fragility fractures in Eurasian countries, with expected demographic changes and poor diagnostic resources exacerbating the problem. The report highlights the need for urgent action to address this growing health issue.
Two multi-year studies will investigate patient experiences with mental-health teletherapy services, including effects on engagement and treatment outcomes. Researchers aim to identify traits of individuals who benefit most from digital therapy, and develop personalized entry points to teletherapy.
A comprehensive analysis by RAND Corporation reveals that transforming the US mental health care system is possible. The report emphasizes the need to integrate behavioral health into general health care settings, provide supportive housing for the homeless, and promote comprehensive mental health education.
A NIH-supported workshop reveals gaps in knowledge about the effects of traumatic brain injury (TBI) in women, including sex-based differences in outcomes and responses to treatment. Research opportunities include imaging studies, examination of brain tissue, and longitudinal studies on military-related TBI in female servicemembers.
Researchers have identified six distinct subtypes of prediabetes, differing in disease development and risk. These subtypes can be used to predict individual risk of developing diabetes and secondary diseases, enabling targeted prevention measures.
Researchers review cognitive testing studies and propose using computer simulations to gauge behavioral problems in children with ADHD. The approach aims to provide more information on the complexity of symptoms, enabling clinicians to make life easier for kids with ADHD.
Researchers at TUM found that nocturnal respiratory rates can help predict the success of ICD treatment in heart patients, with a 31.3% survival advantage observed in those with lower breathing rates. The study demonstrates the predictive value of breathing frequency for therapeutic efficacy.
Kaiser Permanente has found that patients are more receptive to using mental health and wellness apps when referred by a clinician. Digital therapeutics such as mental health apps can offer significant help for patients with mild-to-moderate anxiety or depression, reducing stress and anxiety, and improving sleep.
A study found that a traffic light system reduced clinical uncertainty by 70% and improved treatment decisions for doctors. The system, which uses green, yellow, and red lights to indicate risk levels, was shown to decrease pupil dilation and improve treatment outcomes.
A University of Bath expert cautions that digital trackers for mental health are not yet fit for purpose due to unclear links between online and offline behavior. The researcher highlights concerns over privacy, data protection, and the potential impact on vulnerable populations.
Aerosol-generating medical procedures are a concern due to their high SARS-CoV-2 transmission risk. Four key factors discussed in the article highlight the importance of understanding and mitigating these risks.
Researchers used neuroimaging techniques to reveal that severe oxygen deprivation is the biggest cause of malaria deaths in adults. The study found no correlation between brain swelling and death in adult patients, unlike children, who die from respiratory arrest caused by brain swelling.
Researchers developed an AI that can detect the type of post-stroke depression (PSD) in patients, which is crucial for providing the right treatment. The study used a probabilistic artificial neural network to analyze data from 274 patients and found that early detection is key to improving functional recovery.
A recent study by an international team of researchers has discovered a novel link between tRNA fragments and the immune response following stroke. The findings suggest that tRNA fragments may replace microRNAs in monocytes, regulating homeostasis and potentially working in synergy.
A new study published in the Journal of Bone and Mineral Research found that exercise can help minimize bone loss after weight loss surgery. Participants who attended structured exercise sessions had higher bone mineral density measurements compared to those in the control group.
A new study found that DNP treatment in zebra finches reduced their lifespan by 20% over four years. The birds showed no short-term adverse effects but suffered from accelerated aging, highlighting the need for more research on DNP's long-term safety.
A new study has found that short telomeres may contribute to the cause of idiopathic pulmonary fibrosis (IPF), a devastating lung disease affecting thousands in the UK. The research also suggests that reducing stress and increasing exercise may help prevent or treat IPF.
Researchers developed wearable electroanalytical sensors for monitoring chronic skin wounds, detecting biomarkers such as pyocyanin, nitric oxide, and uric acid. The sensors showed high sensitivity and selectivity in simulated wound environments and cell cultures.
A landmark study led by the University of Sydney found that cannabidiol (CBD) in cannabis does not affect driving ability. In contrast, moderate amounts of tetrahydrocannabinol (THC) produce mild impairment lasting up to four hours.
A new review from the European Society of Anaesthesiology and Intensive Care examines COVID-19 intensive care treatment allocation in Italy. The review concludes that using age alone to determine who receives ICU treatment is not fair, emphasizing the need for a more nuanced approach considering comorbidity and functional status.
A new study finds that Medicaid expansion increases health insurance coverage, ability to see a physician, and foot examinations among patients with diabetes. However, it does not improve follow-up examinations, care, or treatment for diabetes, highlighting the need for additional structural changes.
A new algorithm developed by Rensselaer Polytechnic Institute uses chest CT images and non-imaging data to predict COVID-19 patient outcomes. The algorithm was tested on 295 patients from three hospitals and showed promising results in determining the need for ICU intervention.
David T. Felson, a renowned Boston University rheumatologist, has been honored with the Lee C. Howley Prize from the Arthritis Foundation for his groundbreaking research on osteoarthritis (OA). His work has led to significant advances in understanding OA risk factors, treatments, and outcome measurement.
A study from Indiana University School of Nursing and IU Center for Aging Research at Regenstrief Institute found that nursing home residents with POLST forms had a concordance rate of 59% compared to 35% without POLST forms, indicating better matching of care preferences
A case study reveals the effectiveness of calcium channel blockers like diltiazem in treating acute myocardial infarction due to variant angina. Nitrates are also found to be efficient therapy, inhibiting smooth muscle proliferation and arterial matrix protein synthesis.
The OU College of Medicine has partnered with the US Department of Defense to develop training materials and resources to address problematic sexual behavior in youth within the military. Effective treatments, such as cognitive behavioral therapy and family engagement, have shown recidivism rates less than 2%.
A new study published in PLOS ONE describes the use of functional near-infrared spectroscopy (fNIRS) to objectively detect tinnitus. The technology revealed differences in brain connectivity between people with and without tinnitus, and accurately differentiated patients with mild from moderate/severe cases using machine learning.
Researchers emphasize the positive impact of culture and arts on health, citing World Health Organization benefits like social influence, children's development, and mental health support. Integrating art into healthcare services can promote more ethical care and improve trust among staff.
A retrospective study of over 2,800 children with Type 1 diabetes reveals racial disparities in treatment modalities, clinical outcomes, and appointment attendance. Non-Hispanic Black children are more likely to have poor glycemic control and reduced long-term complications due to inadequate technology use.
A new protein marker, neurofilament light protein (NFL), has been found to predict stroke severity and long-term outcomes. The levels of NFL in blood correlate with more severe brain damage and poorer survival rates after stroke.
A large-scale study found that electrical stimulation of the throat improved swallowing problems in patients with neurological conditions, allowing them to be discharged from hospital. The treatment was safe and easy to use, with most patients showing significant improvement in their ability to swallow.
A recent study suggests that formal 'green prescriptions' to spend time in nature for people with mental health conditions may actually undermine some of the benefits. Research found that visits were associated with emotional and wellbeing benefits when done by choice, but not when pressured by others.
A new form of computerized brain-training called Cognitive Bias Modification (CBM) has been shown to reduce early relapse by 17% in individuals undergoing inpatient alcohol withdrawal treatment. The CBM smartphone app SWiPE is designed to train the subconscious brain to avoid alcohol cues and promote healthier behaviors.
Researchers have created a novel, allergen-depleted fragrance with anti-inflammatory properties that soothes xerotic skin. The fragrance, integrated into new Eucerin products, reduces skin redness and improves patient adherence to treatment.
Researchers have improved consistency assessment in meta-analysis by considering statistical power. This new measure can alter the interpretation of meta-analyses. Studies with high statistical power should have stronger effects on results.
A randomized clinical trial found that electroacupuncture significantly reduced pain severity among adults with chronic low back pain. The study compared the effects of electroacupuncture to a placebo treatment, with results indicating a notable decrease in pain severity.
A new research effort led by the University of Tennessee Institute of Agriculture seeks to enhance communication between healthcare providers and rural patients, enabling them to discuss costs and treatment options. The project aims to improve health outcomes for those living in poverty or with limited financial resources.
Researchers found that apigenin improved cognitive and memory deficits in mice with Down syndrome-like characteristics, reducing inflammation and increasing brain growth. This study raises the possibility of a prenatal treatment to lessen cognitive deficits in fetuses diagnosed with Down syndrome through prenatal testing.
A new study has found that establishing a positive clinical rapport between doctors and patients can relieve pain during acupuncture treatment. Patients who mirrored their doctor's facial expressions experienced less pain, while stronger brain alignment was associated with improved treatment outcomes.