Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
Researchers at POSTECH developed a remote magnetic-sensitive artificial catalyst called MAG-NER, which shows high catalytic efficiency within living cells. The catalyst transforms non-fluorescent reactants into fluorescent products through implanting MAG-NER into living cells and applying alternating magnetic fields.
A new treatment option shows promise in improving survival rates for babies with a rare cerebrovascular disorder. The study found that endovascular treatment can reduce the severity of pulmonary hypertension, allowing babies to cross the critical line on their way to survival.
Researchers at LSU Health have discovered a crucial mechanism in brain cell communication that can help protect against stroke. They found that DHA, an omega-3 fatty acid, promotes the survival and integrity of neuronal cells by regulating key proteins involved in this communication.
Researchers at Michigan State University found that nondeceptive placebos can reduce self-reported emotional distress and brain activity related to emotional events. The study showed a significant reduction in brain markers of emotional distress within just a couple of seconds, suggesting genuine psychobiological effects.
A study of 552 older adults found 80% had at least one skin disease requiring treatment, with fungal infections and eczema being the most prevalent. The research also revealed that more than a third had multiple simultaneous skin diseases, highlighting the importance of whole body skin evaluations in this age group.
The NIH Medical Imaging and Data Resource Center (MIDRC) is a collaborative effort to develop new AI-powered diagnostic tools for COVID-19. The center aims to accelerate the development of personalized therapies by analyzing medical images and clinical data, leading to improved patient outcomes.
Researchers explore how women with SE-AN experience it as profoundly embodied, highlighting why treatment becomes more difficult. A new holistic approach is proposed to improve quality of life.
The Society of NeuroInterventional Surgery's 17th Annual Meeting will discuss advances in stroke triage and management, artificial intelligence, robotics, and new findings on racial disparities in stroke treatment. The event will also cover the neurologic impact of COVID-19.
Treatment of unruptured intracranial aneurysms has become substantially safer over the past decade due to advancements in microsurgical techniques and endovascular technology. Endovascular embolization has shown a higher rate of favorable clinical outcomes compared to microsurgical clipping.
Countries in US, Europe struggle with funding, workforce shortages, and technology limitations to address growing demand for Alzheimer's disease treatment. Despite these challenges, initiatives like telehealth models and memory clinics are being implemented to improve access to care.
A pilot study of a combination of platelet-rich plasma (PRP) injection and home-based exercise program showed encouraging results in reducing shoulder pain in wheelchair users with spinal cord injury. Participants reported decreased pain levels, with three describing their pain as 'much improved', after the treatment.
New research map highlights huge variation in ADHD services across the UK, with only 12 dedicated services providing full NICE-recommended treatment. The study found patchy provision of dedicated ADHD services and disparity in service labelling, affecting service users and healthcare workers.
A new study quantifies the effect of a recent sentinel fracture on 10-year fracture probability using data from Iceland's fracture register. The findings provide probability ratios to adjust conventional FRAX estimates by site, enabling early identification and treatment of high-risk individuals.
Researchers analyzed data from the Framingham Osteoporosis Study to explain the decline in hip fracture rates in the US. Lifestyle factors such as reduced smoking and excessive alcohol consumption contributed to the decrease, highlighting the importance of public health interventions.
A RAND Corporation report highlights shortcomings in treating veterans with co-occurring disorders, emphasizing the need for standardized evidence-based treatments and regular evaluations. The study recommends incorporating veterans' preferences into care decisions and exploring telehealth options during the pandemic.
Researchers at Flinders University warn that family members can be the first to detect early signs of a problem gambler. Chronic hypervigilance, relationship conflict, and exhaustion are common consequences for partners and families.
A study published by Norwegian University of Science and Technology found that mindfulness training can effectively help men manage their anger and reduce violent behavior towards their partners. The treatment group showed a significant decline in physical violence, from 85% to 10%, after completing the program.
A clinical trial by Newcastle University found that levothyroxine does not improve cardiac function in patients who have had a heart attack and are suffering from mild or subclinical hypothyroidism. The treatment, which is commonly recommended for these patients, may actually be of no benefit.
Researchers found that men are now more likely to visit clinics for Peyronie's disease and low sexual desire, while erectile dysfunction cases have declined. The study suggests a growing awareness of these conditions, possibly driven by increased openness and access to treatments.
A new study by The George Institute for Global Health found that prediabetes is associated with a higher risk of cardiovascular disease and death. Researchers analyzed over 10 million people and found that early detection and proper treatment can have significant benefits in reducing the burden of these conditions.
A new, evidence-based guideline has been created to treat patients with NTM lung disease. The guidelines, developed by experts from leading international societies, provide thirty-one recommendations for the treatment of patients suffering from NTM pathogens.
Researchers found potential benefits of meditation and yoga in reducing stress and inflammation, which can aid in immune system enhancement. These practices may provide additional counteracting effects against certain infectious challenges associated with COVID-19.
A new simplified protocol for treating acute malnutrition in young children shows similar recovery rates as the standard approach but is more cost-effective. The streamlined protocol resulted in $123 less per child recovered and reduced ready-to-use food required, providing a potential solution to addressing the issue of nearly 50 mill...
A study aimed to develop and validate tools for assessing delirium severity in older patients, which could lead to improved prevention and treatment. Researchers identified a set of items capturing the severity of delirium and developed a new instrument for quick and easy administration.
Recent trials of COVID-19 treatments often use time to a positive outcome as a key endpoint, but this may not be suitable when death is a competing risk. The authors propose alternative methods for interpreting treatment effects in COVID-19 studies.
A prospective study of 69 couples found that female partners overestimated their IVF live birth rates by 34%, while male partners expected a 54% higher rate. The study highlights the need for clinics to set realistic expectations and provide individualized prognosis to avoid disappointment.
Researchers at Charité - Universitätsmedizin Berlin have identified a specific nerve bundle as the optimal target for deep brain stimulation in obsessive-compulsive disorder. The study's findings may improve treatment outcomes for patients with severe OCD, which affects over 2% of people worldwide.
A collaborative study has identified NPHS1 as a disease-susceptibility gene for steroid-sensitive nephrotic syndrome in children. Variants in this region of chromosome 19 were found to be associated with the disease, and their impact on nephrin mRNA expression was confirmed.
Academics urge government to introduce statutory levy to deliver reductions in gambling harms, citing industry influence and current lack of regulation. They also highlight the need for independent research funding to prevent gambling harms.
A new survey found that 53% of Americans know some or a lot about burn injuries and treatment, but many are unaware of common risks like applying ice to burns. The survey highlights the importance of being aware of fire-related hazards during summer activities like grilling and using fireworks.
A nationwide study led by Rutgers researchers presents clinical characteristics, treatments, and outcomes of multiple inflammatory syndrome (MIS-C) in children. The study found that symptoms typically appear two to four weeks after COVID-19 exposure and affect the heart and digestive system more frequently.
Researchers at UMBC develop independent vector analysis (IVA) for common subspace extraction (CS) to analyze fMRI data, identifying subgroups of schizophrenia patients with significant clinical significance. The method preserves nuances in data while rendering statistically significant groupings.
A 60-year-old man presented with pseudovesicular papules on the trunk after COVID-19 treatment. The case study provides insights into the clinicopathologic aspects of this rare skin condition. Key findings include the patient's rapid development of symptoms and the distinctive appearance of the lesions.
Research suggests the UK's COVID-19 track and trace system should identify around 36 close contacts for every infected person and detect fewer than 1 in 6 untraced cases. However, it also predicts that a significant proportion of infected individuals may not be identifiable due to shorter encounters.
A recent study published in the American Heart Association found that rural stroke patients are more likely to die from stroke-related complications and receive inadequate treatment. Compared to urban patients, rural patients had lower rates of receiving clot-busting medication and undergoing endovascular thrombectomy, leading to highe...
Researchers found that infecting patients with a safe dose of Necator americanus induces immunoregulatory responses and boosts regulatory T cells, which help control the immune system. The study showed that more than half of patients receiving the hookworm had no new lesions at all.
The American College of Physicians has updated its practice points on the use of chloroquine and hydroxychloroquine for COVID-19 treatment. Despite recent studies, there is still no conclusive evidence to support the use of these medications for either prophylaxis or treatment of coronavirus disease.
A new study analyzed data from over 825 trauma centers in the US to identify factors associated with withdrawing life-supporting treatment in patients with severe traumatic brain injury. The findings suggest that demographic and clinical characteristics play a significant role in these decisions.
A study of high-risk adolescents found those with callous-unemotional traits were more likely to carry and use guns in crimes. These traits, characterized by reduced empathy and emotional regulation, are associated with aggressive behavior and poor treatment outcomes.
A new Health Affairs blog post proposes a three-part strategy to address the impact of sustained psychological and moral distress on healthcare workers. The plan includes prevention measures, building behavioral health treatment capacity, and managing long-term effects, in an effort to prioritize both physical and mental health.
Patients with multiple family members suffering from severe mental disorders require more intensive treatment, but respond equally well as those without a family history. The study found that family mental health affects patients' lives beyond the disorder itself.
A new study suggests that early treatment can help prevent permanent nerve damage and improve recovery in children with less severe forms of spinal muscular atrophy (SMA). German researchers recommend early screening for SMA using newborn screening programs to identify children who may benefit from earlier treatment.
Scientists have found that baboons exhibit a steep age-related cognitive decline, similar to humans, making them a potentially useful model for testing early therapeutic interventions. The findings provide insight into the breakdown of brain systems and may lead to better treatments for Alzheimer's disease.
A new study from Massachusetts General Hospital identifies modifiable and behavioral risk factors that can lead to burnout and suicide among healthcare providers. The research highlights the need for increased screening and treatment to address civil legal issues, mental health concerns, and cultural stigma.
A recent meta-analysis found that the treatment gap between men and women for stroke has narrowed to 13%, with most studies showing differences of less than 1% in thrombolysis treatment rates. The study suggests that additional research is needed to understand why a gap persists and whether it continues to decrease.
A new MRI scan algorithm can detect small changes in knee joints over time, enabling researchers to develop new treatments for arthritis. The algorithm creates a three-dimensional model of an individual's knee joint and automatically identifies areas of cartilage breakdown.
Researchers have identified a new inflammatory syndrome in children linked to COVID-19, characterized by symptoms similar to Kawasaki disease but affecting older children and presenting more often with abdominal pains and diarrhoea. The condition, PIMS-TS, requires close monitoring and early treatment to prevent severe complications.
Researchers found that RSV manipulates two gene receptors in cells to gain entry and infect. The discovery sheds light on how the common respiratory syncytial virus breaks into cells, a key step in infection. Current treatment options are limited, but blocking the interaction of the virus with the receptor may prevent infection.
A recent study found that N-BPs like alendronate are associated with a 24% lower risk of pneumonia and 35% lower risk of pneumonia mortality compared to no treatment. The results suggest that N-BP treatment may also protect against pneumonia, warranting further investigation into its potential for treating COVID-19 symptoms.
A Texas A&M team is developing a microfluidic device called PRESCIENT to rapidly identify antibodies that can neutralize SARS-CoV-2 infection. The device has been successfully tested with the hepatitis virus and can conduct hundreds of tests per second.
Researchers at Medical University of South Carolina report that adding a compound to reduce inflammation improves learning, memory and motor recovery after stroke. The treatment may also extend the treatment window by reducing risk of hemorrhage.
Academic emergency departments have a legal, historical, and ethical obligation to provide safe evaluation and care to anyone in need. The Federal Emergency Medical Treatment and Labor Act (EMTALA) prohibits EDs from turning away patients, ensuring access to medical screening and care for all 120 million ED visitors annually.
A new study published in the Journal of NeuroInterventional Surgery found that ischemic stroke patients are arriving at hospitals and treatment centers an average of 160 minutes later during the COVID-19 pandemic compared to a similar timeframe in 2019. This delay has severe consequences, including impacting survival and recovery.
Researchers found that people who believe depression is biologically caused tend to think it is more severe and long-lasting, but are also more optimistic about treatment. Those with a genetic or brain-related perspective on depression are less likely to hold negative attitudes towards individuals with the disorder.
The COVID-19 pandemic has exacerbated mental health issues among healthcare workers, particularly those at higher risk for chronic stress. A recent commentary recommends that healthcare professionals prioritize their own mental well-being by seeking support from colleagues and resources.
The Harvard Data Science Review special issue delves into the COVID-19 pandemic's complex issues, incorporating data-driven insights to better understand its effects. The rolling publication series offers a unique perspective on the crisis, combining multiple disciplines for a comprehensive understanding.
A study published in Lancet Psychiatry found that adding cognitive behavioral therapy (CBT) to standardised medical care significantly reduced the frequency of dissociative seizures, improved functioning, and enhanced quality of life. Researchers recommend incorporating CBT into specialist care for patients with dissociative seizures.
Researchers found that COVID-19 patients with ischemic strokes tend to be younger and have more severe strokes compared to non-COVID stroke patients. Additionally, the rate of imaging-confirmed acute ischemic stroke in hospitalized patients with COVID-19 is lower globally than for non-COVID patients.
A global study published in The Lancet found that women are less likely to develop cardiovascular disease and experience heart attacks and strokes compared to men. Despite this, women tend to receive more preventative treatments but invasive procedures like bypass surgery are more common among men with similar disease severity.
Adding CBT to standard medical care gives patients with dissociative seizures longer periods of seizure freedom and a greater quality of life. This study suggests that CBT combined with specialist care can improve symptoms and satisfaction for those affected by this condition.