Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
Experts warn that increased alcohol harm during lockdown will have long-term consequences for individuals, families, and communities. The UK's recovery from COVID-19 requires addressing the nation's addiction crisis, which costs the NHS over £3.5bn annually.
A new study found that mindfulness training can help multiple sclerosis patients regulate their negative emotions and improve their processing speed. The four-week program showed benefits over adaptive cognitive training and a waitlist control group.
Research finds that people with Type 2 diabetes experience worse cognitive performance after a stroke compared to those without the condition. However, prediabetes is not associated with similar cognitive decline, emphasizing the importance of early diagnosis and treatment.
Researchers report that vitamin B3 niacin boosts energy metabolism and slows disease progression in mitochondrial myopathy patients by increasing NAD+ levels in blood and muscle tissue. The study reveals niacin's therapeutic effect in delaying disease progression, offering a promising treatment option for this progressive muscle disease.
A randomized noninferiority clinical trial found that internet-based cognitive behavioral therapy for health anxiety had similar effects to traditional face-to-face treatment. The study involved 204 adults with health anxiety and showed that online therapy was effective despite limited therapist-patient interaction.
The American College of Physicians has issued new Practice Points stating that hydroxychloroquine and azithromycin do not support COVID-19 prophylaxis or treatment. However, they may be used in clinical trials with informed decision-making. Additionally, research suggests that RT-PCR tests for SARS-CoV-2 have low sensitivity, particula...
Surgically treated patients fared better than those with functional bracing, showing faster recovery and improved outcomes one year after the injury. However, problems were observed in bracing-treated patients, including 30% requiring reoperation due to fracture union failure.
Researchers found no clinically significant changes in metabolite levels after transcranial direct current stimulation (tDCS) treatment. The study's results support the understanding of tDCS as a safe treatment option, even when considering metabolic effects.
The exclusion of children from COVID-19 clinical trials has significant implications for treatment options in this population. Experts argue that including children in these trials is crucial to develop effective treatments tailored to their needs.
Experts recommend prioritizing patient safety with telemedicine and remote monitoring, while minimizing exposure to COVID-19. Delaying treatment by just 15 minutes can significantly impact recovery outcomes.
Women have a good chance of having a second child with IVF, according to new study. The chances of a second ART baby decrease with maternal age, but successful pregnancies are more likely if treatment is continued and frozen embryos are used.
NAFLD affects 5.7% of adults in the US, progressing to cirrhosis in 39% over 8 years, with risk factors including cardiovascular disease and high cholesterol.
Scientists at RCSI University of Medicine and Health Sciences have discovered a potential new treatment for Sjögren's Syndrome, a disease that causes severe dry eyes and mouth. By reducing the levels of microRNA-744, they were able to reduce inflammation and damage to the eye.
A new study published in Journal of the American Heart Association has found that women and men experience overlapping and distinct symptoms when presenting with acute coronary syndrome. Women are more likely to present with fatigue, pain between the shoulder blades, and shortness of breath, while both sexes often experience chest pain.
A recent study by the University of Georgia found a slower uptake of Medicaid enrollment among low-income obese individuals compared to non-obese counterparts. The study revealed a 5.6% increase in coverage for obese individuals versus 7.4% for non-obese individuals.
A new study from the University of Gothenburg finds that weighted vests can lead to a reduction in body weight and fat mass, particularly when wearing heavy weights, while maintaining muscle mass. The researchers suggest that this is due to a built-in energy balance system that endeavors to keep body weight constant.
Researchers from the University of Cincinnati have published recommendations for stroke therapy during the pandemic, emphasizing that a COVID-19 diagnosis should not prevent patients from receiving life-saving treatment. The guidelines aim to balance patient care with staff safety and scarce resources.
Researchers found that patients with type 2 diabetes have blood vessels resistant to insulin, leading to elevated oxidative stress and vessel dysfunction. A new therapy combining insulin treatment with DPP4 inhibitors shows promise in reversing damaging vascular effects.
Ethicists from Carnegie Mellon and McGill universities recommend prioritizing rigorous research approaches, such as master protocols, to ensure high-quality clinical trials. They argue that crises like the COVID-19 pandemic heighten the responsibility of key actors in the research enterprise to uphold scientific standards.
A new randomized control trial will examine the effectiveness of Goal Management Training, a cognitive remediation strategy, in improving functional outcomes among first responders with PTSD. The study aims to understand changes in brain structure and function using magnetic resonance imaging.
A £100,000 project is harnessing Artificial Intelligence to accelerate ADHD diagnosis in UK adults, addressing the growing wait times for treatments. The AI-powered system can identify clear-cut cases, reducing the need for further assessment and enabling clinicians to prioritize those who require additional support.
The Aalto University-developed decision model helps policymakers balance utilitarian and egalitarian objectives, allocating resources to achieve different population-level objectives. The model is not directly adapted to contagious diseases, but its relevance to testing remains unchanged.
A study found that UK healthcare policies restricting access for non-UK born patients may lead to delays in TB diagnosis and treatment. The median time to treatment increased by 20 days after the policy was introduced.
Researchers found that forty percent of women who suffer from postpartum psychosis do not become ill again. Women with isolated postpartum psychosis may not require medicinal treatment outside the postpartum period, according to a new study published in Journal of Clinical Psychiatry.
A recent study found that young adults in Australia are leaving it 'too late' to seek help for eating disorders due to various barriers. Concerns about autonomy, fear of being a burden, and perceptions of the illness's severity prevent many from seeking professional advice.
A new clinical trial aims to find effective alternative solutions for critically ill COVID-19 patients, reducing the need for treatment with a ventilator and improving patient outcomes. The RECOVERY-RS Respiratory Support trial will compare standard care with non-invasive treatments using masks or high-flow oxygen.
A study found that more than a third of medical staff in China suffered from insomnia during the COVID-19 epidemic, with those experiencing sleeplessness also more likely to feel depressed and anxious. Factors such as uncertainty about disease control and lower education levels were correlated with increased risk.
The American Gastroenterological Association has released official guidance for patients with inflammatory bowel disease (IBD) during the COVID-19 pandemic. According to the AGA, patients with IBD should continue their medication, including scheduled infusions, and stop certain medications if they develop COVID-19 symptoms.
The collection of articles highlights the importance of neuropsychological and psychological applications in neurorehabilitation, addressing various etiologies and recovery outcomes. Innovative treatment methodologies such as solution-focused brief therapy and holistic milieu-oriented neurorehabilitation are also discussed.
Women with IBD had higher rates of Caesarean section and intrauterine growth retardation compared to those without IBD. Those with mild Crohn's disease did as well during pregnancy as women without IBD, but those with more severe disease experienced increased miscarriage and low birth weight.
Patients who undergo peroral endoscopic myotomy (POEM) may develop severe heartburn and regurgitation that requires antireflux surgery. Researchers report this complication, highlighting the need to identify which patients might still benefit from POEM.
A study from Madrid's Hospital Infanta Sofía of COVID-19 testing and treatment in children shows promising results, with over 90% of pediatric patients experiencing mild symptoms or no symptoms at all. The study's findings highlight the importance of early detection and treatment in managing childhood COVID-19 cases.
A new triage system using symptom severity and teleconsultation reduced the time to endovascular thrombectomy (EVT) from 65 minutes to 2 hours and 15 minutes in Stockholm region patients. This led to better patient outcomes, with 34% of EVT patients fully recovering their functional ability compared to 24% in the old system.
A new treatment, SPACE, has been found to be as efficacious as cognitive-behavioral therapy (CBT) in treating childhood and adolescent anxiety disorders. The study enrolled 124 children with existing clinical anxiety disorders and randomly assigned them to receive either SPACE or CBT.
New CT scoring criteria evaluate the progression of COVID-19 pneumonia by assessing both lobe involvement and changes in CT findings. The criteria suggest earlier diagnosis and treatment lead to shorter disease resolution times.
Researchers developed five language outcome measures using expressive language sampling (ELS) to assess treatment efficacy in individuals with fragile X syndrome and intellectual disabilities. The study found that ELS yielded valid and reliable measures for most participants, but were more challenging for younger or less able individuals.
A recent observational study found that opioid-related emergency department visits and hospitalizations decreased in states that implemented the Affordable Care Act's Medicaid expansion. The study suggests that improved access to outpatient treatment has contributed to this reduction.
Researchers have identified two crucial surface proteins, SpyAD and Isp2, that contribute to Group A streptococcus fitness in the female genital tract. This discovery may lead to the development of effective treatments and vaccines for puerperal sepsis.
A study in The Journal of Bone & Joint Surgery found that a fracture liaison service improved bone quality and function for patients with fragility fractures. Patients managed with the service had high rates of osteoporosis treatment and low risk of subsequent fractures.
The study found that farmers know less about pesticides applied to their seeds than those applied in other ways, due to seed treatments being exempt from labeling requirements. This lack of knowledge can lead to overuse of pesticides, harming the environment and farmers' health. The researchers recommend improved labelling of pesticide...
Research from the University of Cambridge found a link between inflammation and protein build-up in various types of dementia. The study suggests that neuroinflammation is a common factor across different neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.
A new study by MIT economists finds that doctors who have immunity from liability lawsuits perform slightly more C-section operations compared to those who are legally liable, about 4% more over a 10-year period. This challenges the common perception that defensive medicine leads to less treatment of patients.
A new study published in Circulation found that noncitizens in the US are less likely to receive treatment for cardiovascular disease risk factors due to lack of insurance coverage and a usual source of care. The disparities were significant, with only 16.5% of noncitizens receiving treatment for high cholesterol.
A new classification system for orofacial pain has been developed by international researchers, providing a common language for medical doctors and dentists to diagnose patients accurately. The system is expected to improve treatment outcomes for individuals suffering from chronic pain in the mouth, jaws, and face.
A recent survey-based study of health professionals from 68 countries found that inadequate treatment services for obesity are prevalent globally. Lack of clear care pathways, high costs, and stigma are among the factors attributed to the shortage of effective treatments.
A £500,000 NIHR grant will be used to investigate the effectiveness of NHS-funded obesity treatment programmes in the UK. The project, BE:COME, aims to determine which components of these programmes contribute to weight loss and identify the best combination for different groups of people.
A new AI-based device has been developed to help diagnose aggressive posterior retinopathy of prematurity (AP-ROP) in newborns. The study found that infants who developed AP-ROP were more premature and had lower birth weights, highlighting the need for early detection and monitoring.
Only 19.8% of Americans have rapid access to endovascular thrombectomy for stroke treatment, highlighting a significant unmet need in stroke care. Researchers evaluated two strategies to optimize access and found that the bypassing model could improve access by 16.7%, making it an optimal solution for resource-strapped areas.
The American Academy of Sleep Medicine recommends integrating AI into sleep medicine to improve diagnoses, predict disease outcomes, and personalize treatments. AI can automate sleep scoring, derive meaningful insights from sleep data, and optimize treatments for patients.
Researchers have developed an improved mobile phone app, QUiPP v2, to determine the risk of preterm birth in women. The app helps doctors identify women at high risk and offer timely interventions to prevent complications and improve survival rates for newborns.
Researchers at Karolinska Institutet in Sweden have discovered a link between cognitive impairment and lasting inflammation after intensive care. Elevated blood levels of HMGB1 protein were found in patients with post-intensive care syndrome (PICS), which can cause impairments in memory, attention, and problem-solving for years.
A study analyzing 5,000 non-surgical rhinoplasties found high efficacy and safety with low complication rates. The procedure involves targeting critical aesthetic points on the nose and using hyaluronic acid filler for reversibility and convenience. Long-lasting results were observed in approximately 32% of patients.
The Eating Disorders Genetics Initiative (EDGI) will help researchers better understand eating disorders and enable the design of new treatments. Up to 5% of the population will experience an eating disorder, with genetic factors involved in some cases.
The NIH Technology Accelerator Challenge aims to develop handheld, digital technologies for detecting diseases with high global impact. The challenge will focus on sickle cell disease, malaria, and anemia, addressing the need for accessible diagnostic tools in low-resource settings.
A new multi-sensor tool tracks subtle changes in multiple sclerosis (MS) patients, allowing for more frequent and quick assessments of disease status and progression. The device, which takes less than five minutes to use, uses a combination of sensors to capture MS-related disability and advancement.
A new study published in Cortex journal reveals that visual rehabilitation therapy improved vision in almost 80% of stroke and traumatic brain injury patients. The NeuroEyeCoach therapy was shown to improve daily activities, such as navigating surroundings, identifying obstacles, and avoiding collisions.
Research in mice finds that targeting overactive immune cells can improve TBI recovery, reducing inflammation and neurodegeneration. Quelling chronic inflammation may offer a new treatment option for long-term recovery from traumatic brain injuries.
Researchers have developed an edible coating using cranberry juice and citrus extract that makes noroviruses more sensitive to gamma irradiation, reducing treatment time by half while preserving food quality. This natural antimicrobial method can prevent cell breakdown and discolouration.
A new study found that two-thirds of patients with unchanged hypertension treatment had normal blood pressure readings at home, highlighting the effectiveness of therapeutic inertia. The study suggests that accepting home blood pressure metrics can improve healthcare quality metrics and patient education.
A new study reveals that patients' ratings of hospitals are more closely tied to hotel-like amenities and services than medical care quality. Hospitality scores have a limited impact on patient survival rates, while factors such as nurse responsiveness and room tidiness have a greater influence on satisfaction.