Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
A recent study reveals that metacognitive therapy significantly reduces the risk of depression relapse, with 67-73% of patients remaining healthy one year after treatment. The therapy teaches patients to recognize and manage negative thought patterns, leading to improved outcomes.
A new clinical trial funded by the National Eye Institute found that vision therapy for convergence insufficiency does not improve reading test scores in children. While in-office vision therapy can improve visual function, it fails to lead to better reading fluency and comprehension.
A Dartmouth study found that healthcare providers' expectations can influence patients' perceptions of treatment effectiveness, even with placebo treatments. Patients reported less pain and indicated higher efficacy when doctors expected the treatment to work.
A new study tracking STEMI patients in North India reveals lower rates of female representation among treated patients and significantly younger patient demographics. The registry aims to provide insights into risk factors, practice patterns, and prognosis to improve treatment outcomes for this underserved population.
A comprehensive register-based study from Aarhus University, Denmark, found a significant association between repeated febrile convulsions and the risk of developing epilepsy and psychiatric disorders. Children who suffered three or more febrile convulsions had a 15% risk of developing epilepsy within thirty years.
A new study found that a combination of oral and topical corticosteroids can effectively treat patients with severe chronic rhinosinusitis with nasal polyps. More than 60 patients experienced well-controlled symptoms without needing sinus surgery.
Treating moderate to severe obstructive sleep apnea with PAP therapy is associated with lower healthcare expenditures. Studies show that increased PAP usage per night leads to a significant decrease in inpatient visits, emergency department visits, and overall acute care costs.
A new phototherapy strategy has been shown to effectively remove carbon monoxide from the blood of rats with and without lung injury. The treatment increased CO elimination rates by threefold compared to ventilation alone, leading to improved survival rates among affected animals.
A recent study published in the Journal of the American Geriatric Society found that melatonin treatment did not reduce the risk of developing delirium following heart surgery. The study included 210 adults and showed a similar proportion of participants experienced severe episodes of delirium in both the melatonin and placebo groups.
Researchers developed a new non-invasive optical imaging system to diagnose and treat dry eye disease. The Tear Film Imager images layers of the tear film with speed and precision, providing nanometer-level insight into subtle changes in each layer.
Burt's Bees research highlights the effectiveness of natural ingredients like bakuchiol in addressing anti-aging concerns and protecting skin from environmental damage. Clinical studies demonstrate improved skin health, reduced sensitivity, and enhanced lip barrier function with nature-based skincare regimens.
A new metabolic discovery by researchers at Cornell University may hold the key to fighting heart disease and Type 2 diabetes. The study identifies two enzymes that convert glucose to erythritol, a sugar alcohol, in human metabolism.
A Rutgers-led study uses artificial intelligence to examine genetic signatures of Crohn's disease, revealing previously undiscovered genes linked to the illness. The AI method accurately predicted whether thousands of people had the disease, holding promise for improved diagnosis and treatment.
A new study found that mosquitoes are more likely to lay eggs in clusters of patches withstanding water, rather than dispersed patterns. This creates hotspots where mosquitoes can breed and transmit diseases like Zika, dengue, and chikungunya.
A new calculator developed by the University of Exeter will help clinicians classify patients with type 1 or type 2 diabetes, reducing complications and misdiagnosis. The calculator combines blood test results with age and BMI to provide a personalized medicine approach.
The Chan Zuckerberg Initiative funds I AM ALS to create open source digital tools for building a movement against ALS and other rare diseases. This support aims to connect patients, caregivers, and scientists to accelerate progress in finding treatments and cures.
Researchers developed a needle-free 'exosome' treatment that reduces wrinkles in UV-exposed mice, improving skin health and collagen production. The treatment uses a jet of air to deliver medications deep into the skin, providing a more youthful appearance.
This observational study found that insulin treatment was used less frequently among older adults (75-79 years) in poor health compared to those in good health. The study also revealed higher discontinuation rates of insulin treatment among those in poor health, suggesting potential implications for diabetes management.
A recent study reveals that dengue virus mutations in its E protein can render vaccines and treatments ineffective. The findings also suggest that lab-adapted strains may not accurately represent clinical strains, highlighting the need for further research.
The National Institute of Mental Health (NIMH) has awarded six research grants to develop a learning health care system for the treatment of early psychosis. The grants aim to improve quality of care and patient outcomes while speeding advances in early psychosis services and science.
A new study by University of Washington researchers found that fluoride varnish has modest anti-cavity effects in preschoolers, with a 12% decline in new cavities. The study calls for cost-effectiveness analyses to determine its value in dental services.
Researchers found that neurons use annexin A11 to ship internal housekeeping instructions via a 'hitchhiking' system, which may lead to new treatments for ALS. Disease-causing mutations tie up deliveries at the cell's loading docks, preventing RNA delivery to neurons.
The SPIRIT program at McLean Hospital offers a flexible protocol to address spiritual needs in patients with various mental health conditions. Studies show that over 80% of patients report using religion to cope with stress, highlighting the program's effectiveness and popularity among patients.
Scientists have gained a better understanding of how movements are generated in the spinal cord, revealing that it's a large network of cells rather than a single command center. This finding may lead to advances in treating neurological disorders such as ALS and spinal cord injuries.
Samantha Kleinberg is developing artificial intelligence that provides personalized information to patients, enabling them to actively manage their health. The research focuses on using wearable data and machine learning to identify causes of diseases and develop more usable algorithms that consider human factors.
A 16-week vegan diet was shown to increase the abundance of Faecalibacterium prausnitzii and Bacteoides fragilis, leading to significant reductions in body weight, fat mass, and visceral fat. Insulin sensitivity also improved in the vegan group.
The Warriors Research Institute, a Baylor Scott & White center, has received a $500,000 grant to expand its telehealth program for Texas veterans and their families. The program offers high-quality, accessible mental health treatment via live video conferencing, with significant improvements in quality of life reported by participants.
A new study by UMass Amherst researchers shows that out-of-state casino gambling among Massachusetts residents decreased significantly after the state's first slot parlor, Plainridge Park Casino, opened in 2015. The study found that only 3-10% of problem gamblers seek professional treatment, highlighting the need for alternative effect...
Researchers found that high blood pressure accelerates cognitive decline, but treating high blood pressure slows it down. Participants ages 55 and older with high blood pressure showed a more rapid rate of cognitive decline compared to those being treated for high blood pressure.
A new drug, BPN14770, has shown promise in protecting against memory loss and nerve damage associated with Alzheimer's disease. The drug inhibits phosphodiesterase 4D, an enzyme that plays a key role in memory formation and neuroinflammation.
A study found that Native Hawaiians who participated in a hula dance program significantly lowered their blood pressure compared to those who received standard education. The program, which was tailored to the community's cultural values and perspectives, showed promising results in reducing blood pressure and improving overall health.
Dr. Hossein Tavana's research aims to understand the fluid dynamics of surfactant in premature babies' lungs and improve surfactant replacement therapy for RDS. His lab will generate 3D physical models of airways to aid visualization of surfactant flow, leading to better design strategies.
A new study published in Lancet Gastroenterology and Hepatology found that cognitive behavioural therapy (CBT) tailored for IBS can provide effective, long-term relief despite patients having no further therapy. The research indicates that easily accessible treatment could be provided to a large number of patients with IBS.
Researchers discovered a receptor on brain cells that promotes resilience to stress and may be a useful biomarker for post-traumatic stress disorder (PTSD). The sphingosine-1-phosphate receptor 3 (S1PR3) protein was found to be associated with reduced symptoms of PTSD in human patients.
Researchers from The Westmead Institute for Medical Research have discovered how fatty liver disease develops in lean people. Lean patients tend to have worse outcomes due to an 'obesity-resistant' profile, despite having higher levels of bile acids and FGF19, which increase energy expenditure.
A survey of bereaved Danish parents suggests that doctors often inform them of their child's terminal illness too late, with over four in ten saying they were told just hours before death. The study highlights the need for improved education and training for healthcare professionals on how to break bad news to families.
Researchers investigated metabolic changes across organs in a large animal model of sepsis, identifying common and organ-specific alterations that could inform new therapeutic approaches. The study, published in The American Journal of Pathology, has the potential to reduce mortality and morbidity associated with sepsis.
Scientists at MSD and Francis Crick Institute are working together to better understand Motor Neurone Disease, a devastating disease with no current treatments. The collaboration aims to identify key mechanisms that can kill motor neurons and build scientific understanding for future treatments.
Researchers found that remote ischemic limb conditioning increased inflammatory cells in circulation, reducing brain tissue damage and swelling while improving motor function. The technique has potential for treating strokes of varying severity, offering hope for improved recovery outcomes.
A recent study by University of Edinburgh researchers found that nearly 20% of people waiting for hip replacements suffer from extreme pain or discomfort. The study also revealed that knee replacement patients face similar struggles, with 12% reporting severe health issues.
Researchers explore ultrasound therapy's effectiveness in treating various cardiovascular conditions, including hypertension and arrhythmia. The study highlights the benefits of acoustic intervention, including deep tissue penetration and minimal invasiveness.
Researchers are searching for genetic links to stuttering through a global study recruiting Australian stutterers aged seven and older. The study aims to develop treatments targeting the disorder's underlying cause, rather than just symptoms, with potential benefits for better treatment and prevention of stuttering.
Landos Biopharma has completed a $60 million Series B financing round to support global Phase 2 clinical trials of its lead product BT-11 for ulcerative colitis and Crohn's disease. The funding will also advance additional pipeline candidates, addressing an unmet clinical need for new therapies in inflammatory bowel disease.
The All of Us Research Program has made strong progress in advancing precision medicine by collecting diverse participant data. The program aims to include 1 million or more people from diverse communities, with over 230,000 participants enrolled and 80% from underrepresented groups.
A simple, electricity-independent device has been proven effective in reducing child diarrhea rates by up to 23% in developing countries. The Aquatabs Flo technology uses precise chlorine dosing to purify water without compromising taste, offering a promising solution to control the second-leading cause of death for children globally.
Patients transported by mobile stroke unit receive clot-busting procedure an average of 10 minutes faster than standard ambulance, potentially saving up to 270 million neurons per patient. The quicker treatment can restore blood flow and save neurological function.
Researchers found that smoking did not reduce flares, medication use, hospitalizations, or colon surgery in patients with UC. Smoking cessation also did not worsen the course of disease.
A new study suggests that outdoor light exposure may help prevent myopia in children by thickening the choroid behind the retina. The research aims to develop targeted treatment options to slow down myopia progression and improve eye health.
Researchers at Scuola Internazionale Superiore di Studi Avanzati have developed self-standing carbon nanotubes that can modulate the growth and activity of nerve cells. These innovative materials show promise for repairing spinal injuries by creating biosynthetic hybrids.
Researchers found that Edinburgh has the highest rate of inflammatory bowel disease globally, with one in 98 people expected to be affected by 2028. The study highlights the need for more resources to provide patients with research, treatment, and care.
A recent study published in The Lancet found an AI model can identify patients with intermittent atrial fibrillation using a 10-second ECG test. The technology achieved an overall accuracy of 83% and has the potential to aid doctors investigating unexplained strokes or heart failure.
A study found that smoking impairs the effectiveness of embolization treatment for pulmonary arteriovenous malformations (PAVMs) in patients with HHT. Smokers experienced a higher rate of PAVM persistence after treatment compared to non-smokers, with those who smoked more than 20 pack-years facing a fivefold increased risk.
Researchers investigated acupuncture as an added treatment to reduce frequency of angina attacks in patients with chronic stable angina. The study, conducted in China, involved approximately 400 adults and showed promising results for acupuncture as a complementary therapy.
A group of scientists recommends large-scale collaborative research to tackle dry macular degeneration, with proposed methods including integrated collaboration and biorepository development. The panel aims to bring about meaningful clinical results by promoting multidisciplinary investigator teams.
A global study found that EVT decisions differ significantly between regions and specialties under current local resources, but not under ideal conditions. The most important factors for EVT decisions include NIH Stroke Scale score, level of evidence, patient's age, and clinicians' experience in EVT use.
Researchers present a treatment program to guide effective control of sarcoptic mange disease in wombat populations, building on lessons learned from a previous outbreak at Narawntapu National Park. A longer-lasting treatment and improved delivery are proposed to improve capacity for controlling the disease.
A $1,825,742 NIH grant will fund a randomized controlled trial of strategy-based cognitive training in individuals with multiple sclerosis. The study aims to develop a treatment that improves everyday functioning and neuropsychological performance in those affected by the condition.
A new study from Massachusetts General Hospital's Tobacco Research and Treatment Center shows that daily e-cigarette use helps US smokers quit regular cigarettes. Smokers who used e-cigarettes every day were more likely to quit combustible cigarettes within one year and stay quit for at least another year.
A new NIH-funded study suggests that standard treatment of blood sugar levels after acute ischemic stroke is more effective than aggressive methods in improving patient outcomes. The study found that intensive glucose management increased the risk of hypoglycemia and required higher levels of care.
A new study found that cognitive-behavioral therapy (CBT) can be successful for youth with obsessive-compulsive disorder (OCD), regardless of whether they have hoarding symptoms. The presence of hoarding symptoms did not negatively impact treatment response to CBT in children and adolescents.