Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
Researchers at The University of Queensland have created a new animal model of schizophrenia that specifically targets elevated dopamine levels in the dorsal striatum. This model enables scientists to test potential therapeutics and explore the basic changes in brain circuitry that contribute to the disease.
Researchers use virtual reality to guide catheters through blood vessels with electromagnetic sensors, reducing radiation exposure and increasing precision. The technology has the potential to increase access to interventional radiology treatments in rural areas.
A virtual reality (VR) treatment called ZeroPhobia has been shown to significantly reduce fear of heights symptoms in individuals. By using cognitive behavioral therapy principles in a fully self-guided format, the study found that two to five percent of the population can benefit from this effective and affordable treatment.
A study presented at the Society of Interventional Radiology Annual Scientific Meeting found that training interventional radiologists to perform endovascular thrombectomies improves access to life-saving stroke care. The model expands access to quality, evidence-based care and reduces lifelong disability associated with stroke.
Researchers developed a device-sizing application for Google Home smart speakers to provide accurate medical information and recommendations during procedures. The technology aims to improve patient care by allowing physicians to concentrate on patient care while reducing device technicalities.
The Endocrine Society's Clinical Practice Guideline recommends simplifying medication regimens and tailoring glycemic targets to improve compliance and prevent complications in older adults with diabetes. The guideline prioritizes blood glucose targets over hemoglobin A1c tests, aiming to reduce cardiovascular disease outcomes.
A University of Maryland School of Medicine study has identified seven bacteria associated with increased risk of spontaneous preterm birth, while higher levels of a natural antimicrobial peptide may lower this risk. The findings hold promise for early diagnosis and prevention of premature births, particularly in African American women.
Researchers at the National Eye Institute have developed a new imaging method that uses fluorescent dye to track changes in the retinal pigment epithelium (RPE) layer. The technique reveals unique patterns in individual cells, providing insights into disease progression and treatment options.
Researchers found that individuals with more severe delusions sought more information before making a guess, supporting the idea of 'sticky' beliefs. The study suggests that cognitive training and neurostimulation may help shape inference-making and treat delusions.
A new study reveals that osteoarthritis (OA) and rheumatoid arthritis (RA) have comparable impacts on patients when first visiting rheumatologists. Treatment significantly improves RA outcomes, whereas OA experiences a higher burden of disease, highlighting an urgent need for improved treatments.
A study published in Journal of Neuroscience found that replacing expected aversive events with neutral tones can improve PTSD treatment outcomes. By changing how the brain learns to respond to fearful conditions, researchers hope to develop a new approach to exposure therapy.
The International Registry of Acute Aortic Dissection (IRAD) has gathered data from 9,000 patients, revealing nearly 90% of type A dissections now receive surgical repair. In-hospital mortality is down to 16.3%, and five-year survival remains around 85%. IRAD also shows improved outcomes for type B dissections with endovascular therapy.
Researchers found that using a CPAP machine consistently improved cognitive function for people with MCI, while inconsistent use accelerated decline. The study suggests that consistent CPAP adherence may be an effective strategy to slow memory loss in older adults.
Researchers at the University of Akron aim to understand how lipid mediators exacerbate asthma symptoms, hoping to discover new treatments. The study will combine leukotriene and prostaglandin blockers to create a more potent asthma treatment.
A new preclinical study published in JNeurosci found that switching mice from saturated fat-based diets to monounsaturated fat-rich diets restored and protected nerve function in obese mice. The results suggest that interventions targeting dietary fats may provide a new therapeutic avenue for the treatment of diabetic neuropathy.
Patients with heart failure and a leaking heart valve who underwent transcatheter mitral valve repair reported significant improvements in quality of life after two years. The study found that patients treated with the procedure had better rates of survival and fewer symptoms, leading to improved daily activities.
A recent study found that less than 10% of US doctors' treatment recommendations for heart patients are based on evidence from multiple large, randomized clinical trials. The majority rely on lower-quality data, with only 8.5% supported by Level A evidence.
Researchers found that a unique combination of light and sound improved cognitive and memory impairments similar to those seen in Alzheimer's patients. The treatment also greatly reduced amyloid plaques in the brains of mice, clearing large swaths of critical brain areas.
A study of 3000 IVF births found average birthweight increased by 180g, despite low initial risks. Embryo freezing may mitigate this risk, suggesting a lower health impact on newer IVF children.
Researchers are seeking to recruit 10,000 participants over 60 without Parkinson's for an annual online questionnaire and tests to develop a predictive algorithm. Early detection could lead to treatments that slow or prevent the condition's progression.
A team of scientists developed a machine learning algorithm that identifies children with juvenile arthritis with nearly 90% accuracy from a simple blood test. The new findings pave the way for improving diagnosis and predicting which patients respond best to different treatment options.
Researchers developed a machine learning model to predict recovery time from sports-related concussions based on symptoms like headache, dizziness, and fatigue. The study found that symptom-based prediction models demonstrated practical clinical value in estimating sport-related concussion recovery time.
Scientists discovered consistent brain activity patterns in people with autism that could be used to track treatment progress. The findings suggest that altering these patterns may help improve symptoms, but further studies are needed for confirmation.
A recent study found that disclosing bed bug infestations to potential tenants can lead to cost savings for landlords within five years. The legislation also aims to reduce the spread of bed bugs by promoting prompt treatment and respect for tenant rights, ultimately benefiting public health.
The partnership will provide insights into disease progression and responses to treatment, helping clinicians identify risk factors and inform personalized treatment planning. The project's goal is to promote proactive and tailored care to prevent disease deterioration and improve patient outcomes.
Researchers identified a brain circuit in singing mice that enables high-speed conversation-like exchanges, providing insights into the causes of speech disorders. The study uses Alston's singing mice as a novel mammalian model to examine brain mechanisms behind vocal turn-taking.
Scientists successfully demonstrated that electroencephalography can be used to accurately study activity in the deep areas of the brain. This breakthrough technique may lead to better understanding and treatment of diseases such as Parkinson's, Tourette syndrome, and obsessive-compulsive disorders.
A study found that chelated calcium improves leaf mechanical strength in poinsettias, enhancing their resistance to physical damage. This treatment is recommended for stock plants to improve postharvest quality during shipping and propagation.
The new WHO strategy aims to reduce the death and disability burden of snakebite by 50% by 2030 through delivering effective treatments and strengthening health systems. It also emphasizes empowering communities and building a global coalition to coordinate action and mobilize resources.
Chronic stable angina affects approximately 10 million Americans, primarily older adults and women. Common comorbidities like diabetes are associated with poorer outcomes in this subgroup. The study highlights the growing prevalence of recurring ischemia, its socioeconomic burden, and therapeutic targets for management.
Researchers have developed a new technique to simultaneously measure blood clotting and the formation of free radicals, shedding light on their role in blood vessel damage and disease development. The discovery could lead to better treatments for conditions like heart disease, stroke, and vascular dementia.
A virtual reality therapy called Blue Room has shown lasting effects on anxiety caused by autism phobias in both children and adults. The treatment, developed by Newcastle University, has been shown to be effective in reducing symptoms in 40% of treated children at two weeks and 45% at six months.
A four-year, $1.3 million grant from the National Institutes of Health will support the development of a decision-making tool to help care providers tailor treatments for intimate partner violence (IPV). The project aims to reduce inequalities in current treatment methods and improve outcomes for victims and perpetrators.
An estimated 7.7 million American children have at least one mental health disorder, with prevalence varying widely by state. Policy efforts are needed to improve treatment for children with mental health disorders, which affects up to 72% in some states.
The study found that mechanical clot removal is safe and effective for stroke patients with minimal brain tissue damage, but larger strokes and longer treatment times lead to worse outcomes. Functional independence rates decreased as stroke size increased, while complications like brain bleeds and deaths increased significantly.
Researchers at Rensselaer Polytechnic Institute have successfully applied their big data-based approach to evaluating possible treatments for autism. The findings have the potential to accelerate the development of successful medical interventions by analyzing correlations between metabolite concentrations and adaptive behavior.
Researchers developed a blood test to diagnose autism and applied a big data-based approach to evaluate potential treatments. They used machine-learning algorithms to analyze complex data sets, revealing correlations between metabolite concentrations and changes in behavior.
A new study published in JAMA Pediatrics found that adolescent athletes who underwent a supervised aerobic exercise regimen recovered more quickly from concussions. The research, which is the first randomized clinical trial of its kind, suggests that prescribed, progressive sub-symptom threshold exercise can be an effective treatment w...
A new study explores the treatment of aortic stenosis in older patients, revealing that frailty is a strong predictor of functional decline after surgery. The research highlights the need for patient-centered decision-making to balance quality of life with longevity.
A major Australian study has found that suicidal thoughts do not accurately predict suicide, challenging a widely held belief. The meta-analysis of 70 studies showed that only 1.7% of people with suicidal ideas died by suicide, while about 60% of those who did die had denied having suicidal thoughts.
The American Geriatrics Society recommends excluding feeding tube preference from Physician Order for Life-Sustaining Treatment (POLST) forms due to research showing that they harm patients with dementia. PEG tubes can increase discomfort and agitation, leading to restraints and bedsores.
Researchers developed an adaptive treatment strategy to identify patients at risk of treatment failure in Internet-delivered CBT. The study found that adjusting the treatment to accommodate individual needs can significantly improve outcomes for those at high risk.
A new AI-powered app will monitor patients' symptoms between medical appointments and predict flare-ups using video and thermal imaging technology. The Flare Profiler aims to provide earlier detection of issues, allow earlier clinical intervention, and reduce the need for costly acute treatments.
A randomized clinical trial involving 9,400 adults with hypertension found that intensive blood pressure control did not significantly reduce the risk of probable dementia. Early study termination and fewer than expected cases of dementia may have limited the power to detect a difference.
Researchers have identified distinct brain patterns that respond differently to learning danger and safety in individuals with varying levels of PTSD symptom severity. The study found that more severely symptomatic veterans exhibited greater corrections in physiological arousal and brain activity when faced with unexpected stimuli.
A computer-based decision aid did not alleviate symptoms of depression, anxiety, or post-traumatic stress for family caregivers making end-of-life decisions. The tool's recommendations were often disregarded in favor of more aggressive treatment options.
Researchers explore how AI can analyze words and phrases, turn-taking patterns, and tone to improve medical communications. The technology has potential to revolutionize patient care by providing clinicians with assessments of their communication skills at lower costs.
A recent study published in The BMJ found that wearing a cast for three weeks is just as successful as the conventional six-week treatment period for treating Weber B-type ankle fractures. This discovery could lead to shorter and more convenient treatment strategies, reducing patient discomfort and costs.
A new study finds that offspring whose mothers had complicated pregnancies may be at greater risk of heart disease later in life. The research suggests that the prenatal environment can directly influence long-term cardiovascular health. Antioxidant therapy during pregnancy could potentially protect against heart disease in offspring.
A University of Adelaide study found that orthodontic treatment has no long-term impact on dental health. The research followed 448 participants from age 13 to 30 and found that those with straight teeth still required regular brushing and check-ups to prevent decay.
Researchers at Vanderbilt University have made significant findings on how the brain processes visual information from both eyes. Contrary to previous Nobel Prize-winning research, they discovered that the brain combines dual signals in milliseconds, not later stages of processing.
International study finds MS treatments can delay secondary progressive stage of the disease by five years or more, improving quality of life. Early treatment is essential to prevent worsening disability and irreversible loss of function.
A study found that over two-thirds of patient organizations involved in assessing NHS treatments received funding from the manufacturer or a competitor, yet decision-makers were aware of less than a quarter of these interests. The researchers advocate for stronger policy on disclosure and greater transparency to reassure the public abo...
A new study published in The Lancet found that medically assisted reproduction does not increase the risk of preterm birth and low birth weight. Couples can now consider fertility treatment without worrying about harming their baby.
Among American Indians and Alaska Natives, 41% have lifetime alcohol use disorder; 34% seek alcohol-related treatment. Men aged 35-64 are most likely to receive treatment, with 20.5% of non-Hispanic Whites also seeking help.
The study reviewed comprehensive AIDS prevention programs in prisons, which have been shown to increase prisoners' awareness of AIDS and reduce HIV transmission. These programs also promote the use of condoms, improve healthcare access, and decrease the risk of disease transmission.
A comprehensive meta-analysis of adults with autism found significant impairments in four key domains: theory of mind, emotion perception and knowledge, processing speed, and verbal learning and memory. The study highlights the importance of a broader approach to treating autism in adults, including non-social cognitive domains.
A new neurostimulator, WAND, can stimulate and record electric current in the brain simultaneously, potentially delivering fine-tuned treatments to patients with diseases like epilepsy and Parkinson's. This closed-loop system allows for real-time adjustments, enabling improved outcomes and accessibility.
A new study found that reducing alcohol use can lower nicotine metabolite ratio in heavy drinkers trying to quit smoking. This biomarker is linked to nicotine metabolism and quitting difficulties.
Researchers at Osaka University have developed a method to make industrial polymers adhesive without the need for adhesives or corrosive chemical treatments. This breakthrough enables vulcanized rubber and plastic PTFE to adhere strongly to each other, or to glass and copper, using surface chemistry.