Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
The VERDICT trial found that postponing invasive examination and treatment for up to 72 hours is as good as a very early approach in patients with NSTE-ACS, particularly those with high risk. This contradicts ESC guidelines on immediate versus early invasive strategies.
A new catheter-based sclerotherapy technique is a safe and effective treatment for endometrial cysts, decreasing their size and relieving pain. The procedure also preserves ovarian function and improves future fertility outcomes.
Researchers found that reducing secondary mitral regurgitation in heart failure patients did not improve survival or symptoms, suggesting the procedure is futile. Despite successful procedure completion, there was no significant difference in primary endpoint outcomes between intervention and medical treatment groups.
A new study suggests that incorporating heart scans into routine care could save thousands of lives in the UK. The SCOT-HEART study found that patients who received a computed tomography angiogram (CTA) scan had a 40% lower risk of heart attack within five years.
A UCLA study reveals that magnetic stimulation of the lower spine can restore significant bladder control in people with spinal-cord injuries. The treatment improved patients' quality of life by an average of 60%, allowing them to urinate voluntarily for up to four weeks between treatments.
Diabetologists are filling a crucial gap in patient care, but their growth is hindered by resistance from payers and colleagues. The new medical specialty aims to provide comprehensive diabetes management, but challenges persist due to reimbursement issues and varying opinions on scope of practice.
Thrombospondin-1 plays a critical role in mechanotransduction and elastic fiber organization, contributing to the development of Thoracic Aortic Aneurysms. Deletion of Thbs1 prevents aneurysm formation, restoring aorta biomechanical properties.
Researchers emphasize social and trust-building measures for robots in rehabilitation, recognizing the importance of cooperation and adaptability. They highlight the need for robots to recognize patients' aims and motives and be tailored to individual needs to achieve successful therapy.
A Danish national register study found a higher risk of suicide among those with traumatic brain injury (TBI) compared to the general population. The risk was particularly high among those with severe TBI, multiple medical contacts, and longer hospital stays.
RCSI and Bayer are working together to create new, tailored treatments for people with severe haemophilia. The goal is to promote blood clotting with increased precision, improving the quality of life for those affected by this condition.
Recent MRI studies have revealed various neural manifestations of depression, including abnormal brain activities and white matter damage. These findings suggest that MRI biomarkers may be useful for early diagnosis and treatment outcome evaluation.
A new study finds that lesbian, gay and bisexual adults have similar rates of health insurance as their straight peers but are more likely to avoid necessary medical treatment due to cost. They also report higher levels of poor health days and mental health issues compared to their straight counterparts.
A three-week intensive outpatient treatment program reduced PTSD symptoms by more than half in military veterans, with over 90% sticking to the program. The program combined evidence-based therapies like Cognitive Processing Therapy with wellness interventions, showing that concentrating therapy over consecutive days can be an effectiv...
A highly flexible and stretchable sensor can measure blood flow in brain aneurysms, reducing the need for expensive diagnostic procedures. The sensor uses capacitance changes to detect fluid flow, enabling real-time monitoring of hemodynamics after surgery.
The recommendations aim to improve timely and accurate diagnosis of Alzheimer's disease by emphasizing a multidisciplinary evaluation approach. The guidelines also focus on compassionate communication with patients and caregivers, and establishing a structured assessment process.
A new study published by the American Thoracic Society found that supplemental oxygen eliminated the rise in morning blood pressure experienced by OSA patients who stopped using CPAP. The study suggests that intermittent hypoxia is the dominant cause of daytime increase in blood pressure in OSA.
A study of over 90,000 patients found women's heart failure mortality is higher and hospitalization rates have increased in women compared to men. The research highlights sex differences in heart failure outcomes, care delivery, and access in Ontario.
A study published in Neurology found that despite rapid diagnoses, diagnostic inaccuracy occurred in 6.9% of patients, but only worsened outcomes in 0.8% cases
A randomised controlled trial found that automated virtual reality therapy can be as effective as exposure to real-life heights in reducing fear, with participants reporting a significant reduction in fear levels after treatment. The study provides proof of concept for future psychological interventions and could increase access to men...
Researchers found that repeated testing in middle-age men produced a practice effect, obscuring true cognitive decline and delaying detection of mild cognitive impairment (MCI). This has significant clinical consequences, as it can lead to misdiagnosis and delayed treatment for Alzheimer's disease (AD).
A study from Lawson Research Institute and Western University found that patients experienced lasting improvements in managing symptoms, academics, work performance, and relationships. Patients credited a collaborative partnership with their care provider for keeping them engaged in treatment.
A combination treatment has safely enhanced the ability of the immune system to fight infections in the elderly, reducing their incidence by a year. The treatment, which inhibits TORC1 protein complex, showed improved immune response towards seasonal influenza vaccine, paving the way for therapies targeting infectious diseases.
A new study found that six out of eight state-level policies aimed at reducing alcohol use during pregnancy have unintended consequences, leading to worse birth outcomes. These policies included mandatory warning signs, child abuse laws, and civil commitment laws, which made women reluctant to seek prenatal care.
Researchers found Mindfulness based Cognitive Therapy (MBCT) significantly reduces tinnitus severity compared to relaxation-based treatments. MBCT teaches patients to 'allow' and 'accept' tinnitus, leading to a less intrusive experience.
Scientists successfully isolate and grow human follicles to 'biofunctionality' on a bioengineered ovarian scaffold made of decellularized tissue. The breakthrough uses early-stage follicles from patients with frozen ovarian tissue for fertility preservation.
Researchers report a higher incidence of PAH after cryolipolysis, with 15 events in 11 patients representing 0.72% of treatments, highlighting the need for caution and careful management when dealing with this complication.
A new study by MIT economists challenges the idea that most Medicare spending goes to patients who are unlikely to survive. The research found that less than 5% of Medicare spending is allocated to the top percentile of high-risk patients, with a predicted one-year mortality rate of just 46%.
A new study published in PLOS Medicine found that patients covered under Medicare's fee-for-service plan spent more time in nursing homes after hip fracture hospitalization, yet saw slightly worse health outcomes. In contrast, those covered under Medicare Advantage had shorter stays and similar or better health outcomes.
A new web-based 'Outcome Feedback' technology has been found to reduce the probability of NHS patients with depression deteriorating during psychological treatment by 74%. The study involved over 2,000 mental health patients across multiple NHS Trusts in England.
A pilot study found that a simple problem-solving task activated the region responsible for memory function in athletes with concussions, potentially improving symptoms of depression and anxiety. The research challenges current guidelines recommending total inactivity after a brain injury.
Researchers have developed a smart stent that continuously tracks blood flow through the artery, detecting subtle changes in its condition. This allows for early diagnosis and treatment of restenosis, reducing the risk of additional complications.
Researchers have discovered a pesticide-free way to limit mosquito populations by introducing hungry minnows into breeding areas. The study found that this method can reduce adult mosquito numbers capable of carrying the disease, providing a low-maintenance and cost-effective alternative.
A new algorithm detects subtle changes in arthritic joints using 3D CT images, outperforming current x-ray methods in sensitivity. This could lead to earlier osteoarthritis diagnosis and more accurate treatment assessments.
A study found that 46% of women with early rheumatoid arthritis did not achieve remission within a year, while 38% of men experienced the same issue. Lifestyle changes such as smoking cessation and weight reduction may facilitate rapid reduction of inflammation in early RA.
Researcher Phillip Owens aims to find better treatments for heart disease by studying PAR2 receptor's role in atherosclerosis. High cholesterol significantly increases risk of arterial thrombosis through modification of coagulation proteins.
A new study by University of Warwick found that high-tech negative pressure wound therapy devices do not improve patient recovery or reduce healthcare costs compared to standard dressings. The research suggests that the use of these devices may need to be re-evaluated in light of the findings.
A study by University of Seville researchers found that deep-freezing orange juice can increase the absorption of carotenoids, including phytoene and phytofluene. Freshly squeezed orange juice, however, had a higher concentration but lower bioaccessibility of these compounds.
A Northwestern University study found that carbon dioxide gas injections eliminate fat around the stomach, but modest changes were not sustained over six months. The technique is considered safe and non-invasive, offering an alternative to existing methods for fat reduction.
Research published in The Journal of Physiology shows adult offspring born to older mothers are more susceptible to heart risks. Older motherhood is linked to increased risk of complications during pregnancy and potential health issues for children later in life.
Researchers have identified a new less-invasive treatment option for patients with Acute Respiratory Distress Syndrome (ARDS), using ultra-protective mechanical ventilation. This approach may mitigate further lung injury and improve outcomes without requiring extracorporeal carbon dioxide removal.
A study published in the European Society of Anaesthesiology and Intensive Care suggests that nail treatments do not impact digital pulse oximetry readings. Experimental results found no significant variation in blood oxygen saturation levels, even under different physiological conditions. The findings contradict widespread concern and...
The new guidance, developed by experts at the University of Exeter Medical School, aims to improve quality of life for older adults with type 2 diabetes. For the first time, it provides guidance on stopping treatment in particularly frail adults, a move welcomed by Diabetes UK.
Researchers found that proxies more accurately predict length of life left and are less likely to agree to burdensome treatments for residents believed to have less than 6 months left. This discovery was published in the Journal of the American Medical Association Internal Medicine.
A study analyzing 3,006 patients found that those from lower socioeconomic backgrounds experienced longer delays in receiving hospital care for stroke or transient ischemic attack. This can lead to reduced efficacy of emergency treatments due to time constraints.
Research on permanent pacemaker implantation after TAVR shows a significant impact on patient outcomes, with those requiring implants experiencing poorer survival rates and longer hospital stays. The study's findings highlight the need for closer monitoring and management of conduction disturbances following TAVR procedures.
A new study published in Psychiatric Services found that a mobile health (mHealth) intervention was equally effective to a traditional clinic-based group intervention for individuals with serious mental illness. The mHealth approach, FOCUS, improved treatment engagement and recovery outcomes at six-month follow-up.
A new smartphone app has been shown to be equally effective in treating people with schizophrenia, bipolar disorder, and major depression as traditional clinical interventions. The app, called Focus, had a significantly better rate of treatment engagement and was more convenient for patients.
Researchers analyzed WASH and IPC data from two Ebola treatment centers in Sierra Leone, finding strong correlations between patient population size, disinfectant usage, and personal protective equipment use. The study's findings can aid planning and management of facilities for future Ebola outbreaks.
A new CDC study reveals that permethrin-treated clothing is effective in repelling disease-carrying ticks, with the insects experiencing sluggish movement after contact. The study found strong toxic effects on three primary tick species, including blacklegged and lone star ticks.
Boston Medical Center is conducting a study to test the efficacy of two different methods of delivering cognitive behavioral therapy - face-to-face or online - to children with anxiety. The study aims to determine which format is more effective for patients, particularly those in lower-income and minority families.
Researchers developed a microdialysis technique to measure brown fat's chemical make-up, discovering its activation under both cold and warm conditions. The findings offer potential targets for therapies boosting brown fat's energy-burning power for weight loss.
Under the new guideline, an estimated 31 million more US adults will have high blood pressure, requiring antihypertensive treatment. The revised definition of high blood pressure, above 130/80 mm Hg, may lead to increased treatment recommendations.
A novel index of coronary artery stenosis severity called resting full-cycle ratio (RFR) has been found to be diagnostically equivalent to instantaneous wave-free ratio (iFR). The study, presented at EuroPCR, suggests RFR could identify pressure-based stenosis severity independent of timing within the cardiac cycle.
A clinical trial of 179 patients found improvement in facial angiofibroma appearance with topical rapamycin treatment. The use of topical rapamycin is considered safe and effective for treating disfiguring growths in people with tuberous sclerosis complex.
Evolocumab treatment has been shown to effectively reduce lipoprotein(a) levels and decrease the risk of cardiovascular events. Patients with higher baseline lipoprotein(a) levels derived greater absolute benefit from evolocumab treatment, with a 24% decrease in risk of heart attack, stroke, or cardiovascular death.
A new scoring system, known as the Panzi Score, has been developed to assess and treat fistula injuries in women. The tool helps physicians predict surgical success and guides treatment decisions.
A randomized placebo-controlled study found that CPAP treatment significantly lowered resting heart rates during the day and night in patients with OSA and prediabetes. The effects were comparable to those of beta blockers, which block stress hormones and raise heart rates.
A study by UTHealth found that simple imaging on a non-contrast CT scan can be sufficient to determine thrombectomy treatment in stroke patients, achieving identical clinical outcomes as advanced imaging. This basic technique may broaden access to life-saving surgery for more patients, especially in remote areas.
A new clinical trial is underway to test two human monoclonal antibodies designed to treat MERS-CoV infection. The study will enroll 48 healthy adults and administer escalating doses of the experimental antibodies.
Researchers confirm that frontal cortical lesions moderate response to prism adaptation treatment, with improvement seen only in individuals with frontal lesions. The study suggests early identification of patients with hemiparesis and frontal lesions is crucial for optimal recovery.