Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
The study analyzed an insurance database of over 1 million patients with knee osteoarthritis treated between 2007 and 2015. Updated guidelines from the American Academy of Orthopaedic Surgeons led to a decline in hyaluronic acid injections, while steroid injection rates leveled off after a recommendation against its use was made.
A recent study found that 12.1% of end-of-life admissions received non-beneficial treatment, costing the public $153.1 million annually. The new collaboration aims to reduce such treatments and improve end-of-life care.
The study estimated high mortality rates among civilians in Mosul, Iraq, with a rate of 2.09 deaths per 1,000 person-months during the 9 months of military liberation, compared to 0.71 and 0.50 deaths per 1,000 person-months during ISIS control periods for males and females, respectively.
A study of over 800 women found that acupuncture administered prior to and following embryo transfer did not improve live birth rates compared to a sham control. However, the researchers reported psycho-social benefits from acupuncture for women undergoing IVF.
Researchers at Florida State University emphasize the importance of early depression diagnosis in patients with coronary artery disease. Studies have shown that individuals with both CAD and depression experience significantly poorer health outcomes, including a two-fold higher risk of mortality. The article provides criteria for major...
Chronic medical conditions are common in women with urinary incontinence, linked to increased cardiovascular risk. Pulmonary diseases like asthma also affected many women, highlighting the need for prevention and treatment efforts targeting modifiable conditions.
A recent study found that 56% of older Medicare beneficiaries are at high risk of obstructive sleep apnea, yet only 8% have been tested for it. Treatment was prescribed for 82% of participants after diagnosis.
A holistic, community-based approach to detection and case management improves disease prognoses in mycetoma patients. The study successfully trained over 300 care providers and implemented free treatment, reducing patient delay and dropout rates.
A recent study published in Nature found that the ventral midline thalamus (vMT) plays a crucial role in determining how animals respond to visual threats. The vMT sends information primarily to two brain areas, the basolateral amygdala and the medial prefrontal cortex, which turn out to be critical in determining reactions.
A new study found that over half of older adults (56%) have a high risk of OSA, but only 8% have been tested, highlighting the need for increased evaluation and treatment.
Crowdfunding campaigns for unproven stem cell interventions often convey misleading information about treatment efficacy and risks. The study analyzed 408 campaigns, finding that 44% made definitive claims, while 36 mentions of low-risk interventions were reported.
The VR-SRT System, a virtual reality-based treatment for spatial neglect after stroke, aims to enhance therapy participation through immersive training scenarios. This innovative intervention leverages 3D virtual environments to maximize improvement of health and function in stroke survivors with spatial neglect.
A new study published in PLOS Pathogens estimates that nearly 80% of dengue virus infections are caused by individuals with mild to no symptoms who do not seek medical attention. This finding highlights the importance of proactive disease prevention strategies to curb the spread of dengue fever.
The PRECISE4Q project aims to develop computer-based predictive modeling to personalize and optimize treatment strategies for stroke patients. The project will collect large data sets from different sources, integrating them into self-learning computer models to minimize the burden of stroke on individuals and society.
Researchers discovered tiny DNA fragments, mtDNA, in patients' blood samples that are associated with disease flare-ups. These molecules can trigger an inflammatory response and damage to healthy tissues, causing symptoms of bowel diseases like Crohn's and ulcerative colitis.
The QUT Design Lab has partnered with the Sleepy Burrows Wombat Sanctuary to develop an Australian-first 'hospital' burrow for treating manged wombats. The prototype design aims to improve treatment times and survival rates, with data collected in a field study helping refine the design.
A new study presents the world's first series of robot-assisted tracheobronchoplasty, a minimally invasive procedure that expands treatment options for patients with tracheobronchomalacia. The results show significant improvement in pulmonary function tests and patient satisfaction, with low morbidity and mortality rates.
A new study found that intermittent bright light exposure at night can cause significant phase shifts in the body's internal clock, but not necessarily melatonin suppression. This challenges the common assumption that one can be used as a proxy measure for the other.
The MitraClip device has demonstrated improved echocardiogram measurements and six-minute walk test outcomes, with significant reductions in left ventricle volume and NYHA classification. The study also showed substantial improvement in quality of life outcomes for patients with mitral valve regurgitation.
A study published in The Lancet found that excessive oxygen therapy increases mortality among critically ill patients. Data from over 16,000 adult patients with various acute conditions revealed a 21% higher risk of in-hospital death with liberal oxygen administration.
A new study from Case Western Reserve University found that certain PTSD therapies can effectively reduce symptoms for civilians and military veterans long-term. The study analyzed 32 PTSD-related studies and found that patients displayed less intense symptoms up to two years after treatment ended compared to six months post-therapy.
A new Quick Response (QR) code-based system allows patients with Addison's disease to receive urgent clinical management information, improving emergency care. Healthcare professionals expressed a preference for QR code-linked information, and the system has shown promise in preventing unnecessary deaths linked to adrenal crisis.
A study by Aarhus University finds that medical doctors' substance use disorders are exacerbated by legal and social sanctions, leading to a lack of help-seeking behavior. Doctors often turn to self-treatment or performance-enhancing medicine to cope with work pressure, resulting in worsening substance use disorders.
Researchers at Cedars-Sinai Medical Center have developed a new method to study the brain's role in obesity by recreating brain neurons from obese patients' cells. The study found significant differences between super-obese and normal-weight neurons, suggesting genetic mutations may contribute to weight gain.
Research reveals huge variation in gluten-free food prescribing practice in England, with the most deprived areas having the lowest rates. The study found that factors such as clinical commissioning group policies and deprivation levels play a significant role in determining prescribing patterns.
Researchers found that over one-third of patients denying a self-inflicted gunshot wound were likely trying to kill themselves. Hospitalized patients who denied a suicide attempt were nearly 11 times more likely to be discharged without inpatient psychiatric care. Brief psychological interventions can improve treatment outcomes.
A team of scientists, including those from Google, developed a computer program that can identify structures in unstained brain cells. The program learned to spot features such as cell nuclei, dead cells, and specific types of brain cells by analyzing stained images.
Donovan Argueta, a UC Riverside graduate student, has won a $25,000 Ford Foundation fellowship to continue his research on the biological mechanisms driving increased eating behaviors in obesity. The one-year fellowship will allow him to complete his doctoral degree and pursue a postdoctoral position.
The RoSE is a dynamic spine brace that measures 3-D stiffness of the human torso, enabling new treatments for children with spine deformities. The device applies controlled forces to correct abnormal curves, adapting to changes in the torso over time.
Families with elevated psychosocial risks, including parent mental health issues and child behavior problems, are more likely to drop out of weight management treatment. Psychosocial screening early in treatment may improve outcomes for children with obesity.
A new study found that Tai Chi is equivalent to pulmonary rehabilitation in improving respiratory function and quality of life for patients with COPD. The slow, methodical exercise was shown to be effective in reducing symptoms and improving physical performance after 12 weeks of treatment.
Scientists at Scripps Research Institute discovered a new aspect of the flu virus and its interaction with antibodies in the lungs. They found that IgA antibodies can protect against infections through two different ways.
Researchers found that individuals who rate their mental health as 'positive' despite symptoms are less likely to develop depression or psychological distress in the future. This suggests good mental health encompasses coping and adapting to life, not just symptom absence.
Researchers developed a new healthcare model to address both cardiovascular and non-cardiovascular comorbidities in heart failure patients. The study found that non-cardiovascular conditions had a greater burden on patients' quality of life, highlighting the need for an individualized treatment approach.
Researchers have created new metal alloy rods with laquosuperelasticity, capable of restoring shape against large deformation, and high corrosion resistance. These alloys offer promise as biomaterials for bone implants and potential solutions to scoliosis treatment
A Northwestern University-led team has developed a new way to manufacture proteins outside of a cell, which could have important implications for therapeutics and biomaterials. The team successfully produced high yields of proteins with non-canonical amino acids, opening up possibilities for decentralized manufacturing and distribution...
Researchers discovered a key step in blood digestion that can be targeted to disrupt hookworm development. Testing quinolones disrupted hemozoin formation, interrupting development and reproduction, offering promise for new treatments against human-infecting hookworms.
Researchers found that certain nutrient supplements, such as taurine and antioxidants, may improve mental health in young people with psychosis. The study suggests that these nutrients may be effective as an 'add-on' treatment for some patients.
A systematic review of eight clinical trials found that certain nutrient supplements, such as Taurine and antioxidants, may improve mental health in young people with psychosis. The review suggests that these nutrients could be effective 'add-on' treatments when used alongside standard treatment.
A pilot study demonstrates the safety and feasibility of freezing the posterior vagal trunk nerve, which carries hunger signals to the brain, resulting in significant weight loss. The procedure, known as cryovagotomy, showed a 3.6% average weight loss and nearly 14% decline in excess BMI.
Low back pain affects an estimated 540 million worldwide, causing disability and costing £10.7 billion to UK society. UK briefing notes reveal the condition is often mistreated against best practice guidelines, with a 12% increase in years lived with disability over two decades.
Research highlights music therapy's effectiveness in treating traumatic brain injury and posttraumatic stress disorder among military personnel. Studies show that music can rebuild damaged neural connections, promote motivation, and improve patient outcomes.
A new study by the European Association of Urology confirms that gender surgery significantly improves the quality of life for transgender individuals. The study found that 80% of male-to-female patients perceived themselves as women after surgery and experienced a high level of satisfaction with their outcomes.
The University of Texas Health Science Center at Houston (UTHealth) will use the grant to develop a technology-supported program that integrates care across its clinics. The program aims to expand screening, triage, referral, and behavioral healthcare services for patients with unmet post-Harvey needs.
A study by University of Leicester researchers has identified distinct biological variations in lung tissue samples that can help differentiate between mild and moderate/severe asthma. The findings may lead to the development of targeted treatments for specific subtypes of asthma, improving patient care.
Shifting physicians' roles from transactional tasks to personalized care would enhance patient outcomes. Physicians would diagnose and provide tailored care, synthesizing data and advocating for patients.
A study found that 79% of high school athletes with anterior shoulder instability achieved a full return to sport after nonoperative treatment. The Non-Operative Instability Severity Score (NSIS) tool helps identify higher-risk patients who may require other forms of treatment.
The wearable cardioverter defibrillator was associated with a 35% lower risk of death in patients recovering from a heart attack. While it didn't reduce sudden cardiac deaths, the device showed promise as an interim therapy for patients awaiting evaluation for implantable cardioverter defibrillators.
A leading cardiologist has criticized the new hypertension guidelines, which he says could lead to more harm than benefit for certain individuals. The guidelines recommend intensive treatment for patients at a higher risk of cardiovascular disease, but Dr. Robert Phillips argues that those with lower risk may face unnecessary harm.
A review in Journal of Psychiatric Practice recommends cognitive therapies as a favored approach to addressing trauma symptoms in human trafficking victims. Cognitive processing therapy (CPT) shows promise in treating trauma-related distress, with potential benefits including reduced feelings of guilt and shame.
A novel risk assessment tool has been developed to identify patients at higher risk of post-surgical hip replacement dislocations. The tool, used in conjunction with a treatment algorithm, resulted in a six-fold decrease in dislocation rates among high-risk patients.
Researchers have created an innovative method to alleviate common fears by reading out unconscious brain activity and associating feared objects with positive feelings. By using a mental exercise game and leveraging artificial intelligence algorithms, participants can become desensitized to phobic stimuli without encountering the feare...
Researchers identified five distinct subtypes of type 2 diabetes and one autoimmune type, each with unique characteristics and associated complications. These findings may enable tailored treatment approaches for patients with diabetes, moving towards precision medicine.
A new certification program for healthcare associates working with multiple sclerosis patients is now available. The MSHA Certification Examination covers fundamentals of MS and multidisciplinary management, including pharmacologic interventions and patient empowerment.
Researchers led by Kevin Messacar have found that Enterovirus D68 (EV-D68) is a likely cause of Acute Flaccid Myelitis (AFM), a rare illness affecting children. The study advances prevention and treatment efforts, with improved awareness, surveillance, and investigations underway.
In humans, a massive wave of electrochemical energy release in the brain occurs after oxygen deprivation, known as 'spreading depolarization', which can trigger pathophysiological cascades. Researchers have found that this event is similar to animal studies and that it remains reversible if circulation is restored before nerve cells die.
The NIH-led AMD Ryan Initiative Study (ARIS) will follow 500 people over five years to learn more about the natural history of early age-related macular degeneration (AMD). Researchers aim to identify biomarkers of disease progression and develop therapies to halt its progression.
A new Annals of Neurology study investigated the mechanisms and timing of events in the brain and circulation during the dying process. The findings suggest that spreading depolarization marks the loss of stored energy in brain cells, leading to death, but also highlight its reversibility with restored circulation.
A new study suggests that women in eating disorder treatment need more informative and personalized reproductive health advice, rather than vague warnings. The research found that participants felt fertility information was delivered as 'blackmail' or 'scaremongering', leading to feelings of self-blame and low motivation for recovery.
A groundbreaking new wearable device is being presented at the AAAS annual meeting, which uses stretchable electronics to monitor patients' swallowing ability, heart function, muscle activity, and quality of sleep. The sensor aids in aphasia diagnosis and treatment, providing a 'game-changer' for stroke recovery outcomes measurement.